Gene: ENSG00000137474 (Homo sapiens)

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Gene Identifier
ENSG00000137474
Transcript Identifier
ENST00000409709
Gene Type
Coding gene
Location
11 : 77130635-77214696 : positive

Family Information

Homologous gene family
HOM02SEM000038
(396 genes in 24 species)
specific family
Orthologous gene family
ORTHO02SEM000037
(364 genes in 24 species)
specific family

Descriptions

gene_descr
myosin VIIA

Identifiers

Type Value
pidENSP00000386331
HGNC7606
UniprotQ13402
RefSeq_mRNANM_000260.3

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0060088
IEA
Genome Projectauditory receptor cell stereocilium organization
GO:0051904
IEA
Genome Projectpigment granule transport
GO:0050957
IMP
Genome Projectequilibrioception
GO:0050957
IMP
Gene Ontologyequilibrioception1
GO:0050953
IMP
Genome Projectsensory perception of light stimulus
GO:0050953
IMP
Gene Ontologysensory perception of light stimulus2
GO:0048563
IEA
Genome Projectpost-embryonic animal organ morphogenesis
GO:0042462
IC
Genome Projecteye photoreceptor cell development
GO:0042462
IC
Gene Ontologyeye photoreceptor cell development3
GO:0030048
IDA
Genome Projectactin filament-based movement
GO:0030048
IDA
Gene Ontologyactin filament-based movement4
GO:0007605
IMP
Genome Projectsensory perception of sound
GO:0007605
IMP
Gene Ontologysensory perception of sound1 2
GO:0007601
IMP
Genome Projectvisual perception
GO:0007601
IMP
Gene Ontologyvisual perception1
GO:0007040
IDA
Genome Projectlysosome organization
GO:0007040
IDA
Gene Ontologylysosome organization5
GO:0006886
IEA
Genome Projectintracellular protein transport
GO:0001845
IEA
Genome Projectphagolysosome assembly
GO:0030036
IEA
PLAZA Integrative Orthologyactin cytoskeleton organization FBgn0000317
GO:0050789
IEA
PLAZA Integrative Orthologyregulation of biological process WBGene00002039
GO:0051716
IEA
PLAZA Integrative Orthologycellular response to stimulus WBGene00002039
GO:0097435
IEA
PLAZA Integrative Orthologysupramolecular fiber organization FBgn0000317
GO:0008407
IEA
PLAZA Integrative Orthologychaeta morphogenesis FBgn0000317
GO:0003002
IEA
PLAZA Integrative Orthologyregionalization FBgn0000317
GO:0022416
IEA
PLAZA Integrative Orthologychaeta development FBgn0000317
GO:0007444
IEA
PLAZA Integrative Orthologyimaginal disc development FBgn0000317
GO:0035295
IEA
PLAZA Integrative Orthologytube development FBgn0000317
GO:0007165
IEA
PLAZA Integrative Orthologysignal transduction WBGene00002039
GO:0035293
IEA
PLAZA Integrative Orthologychitin-based larval cuticle pattern formation FBgn0000317
GO:0007560
IEA
PLAZA Integrative Orthologyimaginal disc morphogenesis FBgn0000317
GO:0048707
IEA
PLAZA Integrative Orthologyinstar larval or pupal morphogenesis FBgn0000317
GO:0035017
IEA
PLAZA Integrative Orthologycuticle pattern formation FBgn0000317
GO:0050896
IEA
PLAZA Integrative Orthologyresponse to stimulus WBGene00002039
GO:0035214
IEA
PLAZA Integrative Orthologyeye-antennal disc development FBgn0000317
GO:0048736
IEA
PLAZA Integrative Orthologyappendage development FBgn0000317
GO:0048737
IEA
PLAZA Integrative Orthologyimaginal disc-derived appendage development FBgn0000317
GO:0007552
IEA
PLAZA Integrative Orthologymetamorphosis FBgn0000317
GO:0007476
IEA
PLAZA Integrative Orthologyimaginal disc-derived wing morphogenesis FBgn0000317
GO:0007591
IEA
PLAZA Integrative Orthologymolting cycle, chitin-based cuticle FBgn0000317
GO:0008363
IEA
PLAZA Integrative Orthologylarval chitin-based cuticle development FBgn0000317
GO:0007154
IEA
PLAZA Integrative Orthologycell communication WBGene00002039
GO:0007472
IEA
PLAZA Integrative Orthologywing disc morphogenesis FBgn0000317
GO:0035220
IEA
PLAZA Integrative Orthologywing disc development FBgn0000317
GO:0035107
IEA
PLAZA Integrative Orthologyappendage morphogenesis FBgn0000317
GO:0023052
IEA
PLAZA Integrative Orthologysignaling WBGene00002039
GO:0002009
IEA
PLAZA Integrative Orthologymorphogenesis of an epithelium FBgn0000317
GO:0042303
IEA
PLAZA Integrative Orthologymolting cycle FBgn0000317
GO:0007469
IEA
PLAZA Integrative Orthologyantennal development FBgn0000317
GO:0048800
IEA
PLAZA Integrative Orthologyantennal morphogenesis FBgn0000317
GO:0007389
IEA
PLAZA Integrative Orthologypattern specification process FBgn0000317
GO:0048729
IEA
PLAZA Integrative Orthologytissue morphogenesis FBgn0000317
GO:0040003
IEA
PLAZA Integrative Orthologychitin-based cuticle development FBgn0000317
GO:0065007
IEA
PLAZA Integrative Orthologybiological regulation WBGene00002039
GO:0035114
IEA
PLAZA Integrative Orthologyimaginal disc-derived appendage morphogenesis FBgn0000317
GO:0035317
IEA
PLAZA Integrative Orthologyimaginal disc-derived wing hair organization FBgn0000317
GO:0035239
IEA
PLAZA Integrative Orthologytube morphogenesis FBgn0000317
GO:0035316
IEA
PLAZA Integrative Orthologynon-sensory hair organization FBgn0000317
GO:0050794
IEA
PLAZA Integrative Orthologyregulation of cellular process WBGene00002039
GO:0032529
IEA
PLAZA Integrative Orthologyfollicle cell microvillus organization FBgn0000317
GO:0032528
IEA
PLAZA Integrative Orthologymicrovillus organization FBgn0000317
GO:0042337
IEA
PLAZA Integrative Orthologycuticle development involved in chitin-based cuticle molting cycle FBgn0000317
GO:0002168
IEA
PLAZA Integrative Orthologyinstar larval development FBgn0000317
GO:0042335
IEA
PLAZA Integrative Orthologycuticle development FBgn0000317
GO:0002165
IEA
PLAZA Integrative Orthologyinstar larval or pupal development FBgn0000317
GO:0002164
IEA
PLAZA Integrative Orthologylarval development FBgn0000317
GO:0008586
IEA
PLAZA Integrative Orthologyimaginal disc-derived wing vein morphogenesis FBgn0000317
GO:0007455
IEA
PLAZA Integrative Orthologyeye-antennal disc morphogenesis FBgn0000317
GO:0007015
IEA
PLAZA Integrative Orthologyactin filament organization FBgn0000317
GO:0035120
IEA
PLAZA Integrative Orthologypost-embryonic appendage morphogenesis FBgn0000317
GO:1904970
IEA
PLAZA Integrative Orthologybrush border assembly ENSG00000169994
GO:0007010
IEA
PLAZA Integrative Orthologycytoskeleton organization FBgn0000317
GO:0060562
IEA
PLAZA Integrative Orthologyepithelial tube morphogenesis FBgn0000317

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0051015
IDA
Genome Projectactin filament binding
GO:0051015
IDA
Gene Ontologyactin filament binding4
GO:0047485
IEA
Genome Projectprotein N-terminus binding
GO:0043531
IEA
Genome ProjectADP binding
GO:0042803
IEA
Genome Projectprotein homodimerization activity
GO:0030898
IEA
Genome Projectactin-dependent ATPase activity
GO:0030507
IDA
Genome Projectspectrin binding
GO:0030507
IDA
Gene Ontologyspectrin binding6
GO:0019904
IEA
Genome Projectprotein domain specific binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0005516
IMP
Genome Projectcalmodulin binding
GO:0005516
IMP
Gene Ontologycalmodulin binding7
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding8 9
GO:0000146
IDA
Genome Projectmicrofilament motor activity
GO:0000146
IDA
Gene Ontologymicrofilament motor activity4
GO:0008134
IEA
PLAZA Integrative Orthologytranscription factor binding WBGene00002039
GO:0032027
IEA
PLAZA Integrative Orthologymyosin light chain binding FBgn0000317
GO:0017022
IEA
PLAZA Integrative Orthologymyosin binding FBgn0000317
GO:0045296
IEA
PLAZA Integrative Orthologycadherin binding FBgn0000317
GO:0050839
IEA
PLAZA Integrative Orthologycell adhesion molecule binding FBgn0000317

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1990435
IEA
Genome Projectupper tip-link density
GO:0045202
IDA
Genome Projectsynapse
GO:0045202
IDA
Gene Ontologysynapse3
GO:0042470
IEA
Genome Projectmelanosome
GO:0032420
IEA
Genome Projectstereocilium
GO:0032391
IEA
Genome Projectphotoreceptor connecting cilium
GO:0031477
IEA
Genome Projectmyosin VII complex
GO:0016324
IEA
Genome Projectapical plasma membrane
GO:0005938
IEA
Genome Projectcell cortex
GO:0005902
IEA
Genome Projectmicrovillus
GO:0005829
IDA
Genome Projectcytosol
GO:0005829
IDA
Gene Ontologycytosol7
GO:0005765
IDA
Genome Projectlysosomal membrane
GO:0005765
IDA
Gene Ontologylysosomal membrane5
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005737
IDA
Gene Ontologycytoplasm6
GO:0001917
IDA
Genome Projectphotoreceptor inner segment
GO:0001917
IDA
Gene Ontologyphotoreceptor inner segment3
GO:0001750
IDA
Genome Projectphotoreceptor outer segment
GO:0001750
IDA
Gene Ontologyphotoreceptor outer segment3
GO:0035324
IEA
PLAZA Integrative Orthologyfemale germline ring canal FBgn0000317
GO:0030312
IEA
PLAZA Integrative Orthologyexternal encapsulating structure FBgn0000317
GO:0099738
IEA
PLAZA Integrative Orthologycell cortex region FBgn0000317
GO:0005615
IEA
PLAZA Integrative Orthologyextracellular space ENSG00000169994
GO:0042600
IEA
PLAZA Integrative Orthologychorion FBgn0000317
GO:0044421
IEA
PLAZA Integrative Orthologyextracellular region part ENSG00000169994
GO:0044462
IEA
PLAZA Integrative Orthologyexternal encapsulating structure part FBgn0000317
GO:0070062
IEA
PLAZA Integrative Orthologyextracellular exosome ENSG00000169994
GO:0005576
IEA
PLAZA Integrative Orthologyextracellular region ENSG00000169994
GO:0035182
IEA
PLAZA Integrative Orthologyfemale germline ring canal outer rim FBgn0000317
GO:0070825
IEA
PLAZA Integrative Orthologymicropyle FBgn0000317
GO:0045180
IEA
PLAZA Integrative Orthologybasal cortex FBgn0000317
GO:0031941
IEA
PLAZA Integrative Orthologyfilamentous actin FBgn0000317
GO:0099513
IEA
PLAZA Integrative Orthologypolymeric cytoskeletal fiber FBgn0000317
GO:0099512
IEA
PLAZA Integrative Orthologysupramolecular fiber FBgn0000317
GO:0044448
IEA
PLAZA Integrative Orthologycell cortex part FBgn0000317
GO:0005884
IEA
PLAZA Integrative Orthologyactin filament FBgn0000317
GO:0045179
IEA
PLAZA Integrative Orthologyapical cortex FBgn0000317
GO:0099081
IEA
PLAZA Integrative Orthologysupramolecular polymer FBgn0000317
GO:0099080
IEA
PLAZA Integrative Orthologysupramolecular complex FBgn0000317
GO:0031476
IEA
PLAZA Integrative Orthologymyosin VI complex WBGene00002039
GO:0043230
IEA
PLAZA Integrative Orthologyextracellular organelle ENSG00000169994
GO:0045178
IEA
PLAZA Integrative Orthologybasal part of cell FBgn0000317
GO:0005903
IEA
PLAZA Integrative Orthologybrush border ENSG00000169994
GO:0045172
IEA
PLAZA Integrative Orthologygermline ring canal FBgn0000317
GO:0045171
IEA
PLAZA Integrative Orthologyintercellular bridge FBgn0000317
GO:1903561
IEA
PLAZA Integrative Orthologyextracellular vesicle ENSG00000169994

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000048IQ motif, EF-hand binding site
IPR000299FERM domain
IPR000857MyTH4 domain
IPR001452SH3 domain
IPR001609Myosin head, motor domain
IPR011993PH-like domain superfamily
IPR014352FERM/acyl-CoA-binding protein superfamily
IPR019748FERM central domain
IPR019749Band 4.1 domain
IPR027417P-loop containing nucleoside triphosphate hydrolase
IPR029071Ubiquitin-like domain superfamily

No MapMan annotations defined for this gene.
KeggID Description
K10359MYO7A, USH1B; myosin VIIa
No chloroplast target sequence found.