Gene: ENSG00000137033 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000137033
Transcript Identifier
ENST00000381434
Gene Type
Coding gene
Location
9 : 6241695-6256168 : positive

Family Information

Homologous gene family
HOM02SEM106143
(orphan gene)
specific family

Descriptions

gene_descr
interleukin 33

Identifiers

Type Value
pidENSP00000370842
HGNC16028
UniprotO95760
RefSeq_mRNANM_033439.3

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0097191
IEA
Genome Projectextrinsic apoptotic signaling pathway
GO:0090197
IDA
Genome Projectpositive regulation of chemokine secretion
GO:0090197
IDA
Gene Ontologypositive regulation of chemokine secretion1
GO:0061518
IEA
Genome Projectmicroglial cell proliferation
GO:0051607
IEA
Genome Projectdefense response to virus
GO:0051025
IEA
Genome Projectnegative regulation of immunoglobulin secretion
GO:0051024
IEA
Genome Projectpositive regulation of immunoglobulin secretion
GO:0050729
ISS, IBA
Genome Projectpositive regulation of inflammatory response
GO:0050729
ISS
Gene Ontologypositive regulation of inflammatory response1
GO:0045944
ISS
Genome Projectpositive regulation of transcription by RNA polymerase II
GO:0045944
ISS
Gene Ontologypositive regulation of transcription by RNA polymerase II1
GO:0043032
IDA
Genome Projectpositive regulation of macrophage activation
GO:0043032
IDA
Gene Ontologypositive regulation of macrophage activation1
GO:0042092
IBA
Genome Projecttype 2 immune response
GO:0032755
IEA
Genome Projectpositive regulation of interleukin-6 production
GO:0032754
IEA
Genome Projectpositive regulation of interleukin-5 production
GO:0032753
IEA
Genome Projectpositive regulation of interleukin-4 production
GO:0032736
IEA
Genome Projectpositive regulation of interleukin-13 production
GO:0032689
IEA
Genome Projectnegative regulation of interferon-gamma production
GO:0032436
IEA
Genome Projectpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0016579
TAS
Genome Projectprotein deubiquitination
GO:0016579
TAS
Gene Ontologyprotein deubiquitination
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0002830
IEA
Genome Projectpositive regulation of type 2 immune response
GO:0002826
IEA
Genome Projectnegative regulation of T-helper 1 type immune response
GO:0002686
IEA
Genome Projectnegative regulation of leukocyte migration
GO:0002282
IEA
Genome Projectmicroglial cell activation involved in immune response
GO:0150078
TAS
Gene Ontologypositive regulation of neuroinflammatory response2
GO:0038172
TAS
Gene Ontologyinterleukin-33-mediated signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding3 4
GO:0005125
IDA
Genome Projectcytokine activity
GO:0005125
IDA
Gene Ontologycytokine activity1

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0030133
IEA
Genome Projecttransport vesicle
GO:0005829
IDA
Genome Projectcytosol
GO:0005694
IEA
Genome Projectchromosome
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005654
TAS
Gene Ontologynucleoplasm
GO:0005615
IEA
Genome Projectextracellular space
GO:0005576
TAS
Genome Projectextracellular region
GO:0005576
TAS
Gene Ontologyextracellular region

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR026145Interleukin-33

No MapMan annotations defined for this gene.
KeggID Description
K12967IL33; interleukin 33
No chloroplast target sequence found.