Gene: ENSG00000136861 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000136861
Transcript Identifier
ENST00000349780
Gene Type
Coding gene
Location
9 : 120389236-120579978 : negative

Family Information

Homologous gene family
HOM02SEM026220
(3 genes in 2 species)
specific family
Orthologous gene family
ORTHO02SEM019974
(2 genes in 2 species)
specific family

Descriptions

gene_descr
CDK5 regulatory subunit associated protein 2

Identifiers

Type Value
pidENSP00000343818
HGNC18672
UniprotQ96SN8
RefSeq_mRNANM_018249.5
EMBLAB046853
EMBLAF448860
EMBLAK001729
EMBLAK025867
EMBLAK027636
EMBLAL133161
EMBLAL138836
EMBLAL353736
EMBLAL391870
EMBLAL590642
EMBLBC004526
EMBLBX537421
EMBLBX537759

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0097711
TAS
Genome Projectciliary basal body-plasma membrane docking
GO:0097711
TAS
Gene Ontologyciliary basal body-plasma membrane docking
GO:0090231
IDA
Genome Projectregulation of spindle checkpoint
GO:0046600
ISS
Genome Projectnegative regulation of centriole replication
GO:0046600
ISS
Gene Ontologynegative regulation of centriole replication
GO:0045893
IDA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045893
IDA
Gene Ontologypositive regulation of transcription, DNA-templated1
GO:0045665
IEA
Genome Projectnegative regulation of neuron differentiation
GO:0045664
NAS
Genome Projectregulation of neuron differentiation
GO:0045664
NAS
Gene Ontologyregulation of neuron differentiation2
GO:0031023
IMP
Genome Projectmicrotubule organizing center organization
GO:0031023
IMP
Gene Ontologymicrotubule organizing center organization3
GO:0022008
ISS
Genome Projectneurogenesis
GO:0022008
ISS
Gene Ontologyneurogenesis
GO:0007420
ISS
NAS
Genome Projectbrain development
GO:0007420
ISS
NAS
Gene Ontologybrain development4
GO:0007099
IMP
Genome Projectcentriole replication
GO:0007099
IMP
Gene Ontologycentriole replication5
GO:0007098
IMP
Genome Projectcentrosome cycle
GO:0007098
IMP
Gene Ontologycentrosome cycle6
GO:0007059
IMP
Genome Projectchromosome segregation
GO:0007059
IMP
Gene Ontologychromosome segregation1
GO:0001578
IDA
Genome Projectmicrotubule bundle formation
GO:0001578
IDA
Gene Ontologymicrotubule bundle formation7
GO:0000226
IDA
Genome Projectmicrotubule cytoskeleton organization
GO:0000226
IDA
Gene Ontologymicrotubule cytoskeleton organization8
GO:0000132
ISS
Genome Projectestablishment of mitotic spindle orientation
GO:0000132
ISS
Gene Ontologyestablishment of mitotic spindle orientation
GO:0000086
TAS
Genome ProjectG2/M transition of mitotic cell cycle
GO:0000086
TAS
Gene OntologyG2/M transition of mitotic cell cycle
GO:0090266
IDA
Gene Ontologyregulation of mitotic cell cycle spindle assembly checkpoint1
GO:0031116
IMP
Gene Ontologypositive regulation of microtubule polymerization9
GO:0010389
TAS
Gene Ontologyregulation of G2/M transition of mitotic cell cycle
GO:0009790
IEA
PLAZA Integrative Orthologyembryo development FBgn0013765
GO:0007292
IEA
PLAZA Integrative Orthologyfemale gamete generation FBgn0013765
GO:0007494
IEA
PLAZA Integrative Orthologymidgut development FBgn0013765
GO:1903046
IEA
PLAZA Integrative Orthologymeiotic cell cycle process FBgn0013765
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction FBgn0013765
GO:0007405
IEA
PLAZA Integrative Orthologyneuroblast proliferation FBgn0013765
GO:0051321
IEA
PLAZA Integrative Orthologymeiotic cell cycle FBgn0013765
GO:0048565
IEA
PLAZA Integrative Orthologydigestive tract development FBgn0013765
GO:0045132
IEA
PLAZA Integrative Orthologymeiotic chromosome segregation FBgn0013765
GO:0042461
IEA
PLAZA Integrative Orthologyphotoreceptor cell development FBgn0013765
GO:0055123
IEA
PLAZA Integrative Orthologydigestive system development FBgn0013765
GO:0010457
IEA
PLAZA Integrative Orthologycentriole-centriole cohesion FBgn0013765
GO:0017145
IEA
PLAZA Integrative Orthologystem cell division FBgn0013765
GO:0036445
IEA
PLAZA Integrative Orthologyneuronal stem cell division FBgn0013765
GO:0048609
IEA
PLAZA Integrative Orthologymulticellular organismal reproductive process FBgn0013765
GO:0000904
IEA
PLAZA Integrative Orthologycell morphogenesis involved in differentiation FBgn0013765
GO:0008594
IEA
PLAZA Integrative Orthologyphotoreceptor cell morphogenesis FBgn0013765
GO:0007143
IEA
PLAZA Integrative Orthologyfemale meiotic nuclear division FBgn0013765
GO:0000902
IEA
PLAZA Integrative Orthologycell morphogenesis FBgn0013765
GO:0048646
IEA
PLAZA Integrative Orthologyanatomical structure formation involved in morphogenesis FBgn0013765
GO:0008356
IEA
PLAZA Integrative Orthologyasymmetric cell division FBgn0013765
GO:0007422
IEA
PLAZA Integrative Orthologyperipheral nervous system development FBgn0013765
GO:0007349
IEA
PLAZA Integrative Orthologycellularization FBgn0013765
GO:0055057
IEA
PLAZA Integrative Orthologyneuroblast division FBgn0013765
GO:0055059
IEA
PLAZA Integrative Orthologyasymmetric neuroblast division FBgn0013765
GO:0016321
IEA
PLAZA Integrative Orthologyfemale meiosis chromosome segregation FBgn0013765
GO:0019953
IEA
PLAZA Integrative Orthologysexual reproduction FBgn0013765
GO:0040016
IEA
PLAZA Integrative Orthologyembryonic cleavage FBgn0013765
GO:0008283
IEA
PLAZA Integrative Orthologycell proliferation FBgn0013765
GO:0061351
IEA
PLAZA Integrative Orthologyneural precursor cell proliferation FBgn0013765
GO:0007279
IEA
PLAZA Integrative Orthologypole cell formation FBgn0013765
GO:0009653
IEA
PLAZA Integrative Orthologyanatomical structure morphogenesis FBgn0013765
GO:0007276
IEA
PLAZA Integrative Orthologygamete generation FBgn0013765
GO:0007277
IEA
PLAZA Integrative Orthologypole cell development FBgn0013765
GO:0051301
IEA
PLAZA Integrative Orthologycell division FBgn0013765
GO:0032504
IEA
PLAZA Integrative Orthologymulticellular organism reproduction FBgn0013765
GO:0032989
IEA
PLAZA Integrative Orthologycellular component morphogenesis FBgn0013765
GO:0048103
IEA
PLAZA Integrative Orthologysomatic stem cell division FBgn0013765
GO:0072089
IEA
PLAZA Integrative Orthologystem cell proliferation FBgn0013765
GO:0051704
IEA
PLAZA Integrative Orthologymulti-organism process FBgn0013765
GO:0140013
IEA
PLAZA Integrative Orthologymeiotic nuclear division FBgn0013765
GO:0044703
IEA
PLAZA Integrative Orthologymulti-organism reproductive process FBgn0013765
GO:0035295
IEA
PLAZA Integrative Orthologytube development FBgn0013765
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process FBgn0013765
GO:0048667
IEA
PLAZA Integrative Orthologycell morphogenesis involved in neuron differentiation FBgn0013765
GO:0048666
IEA
PLAZA Integrative Orthologyneuron development FBgn0013765
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction FBgn0013765
GO:0022412
IEA
PLAZA Integrative Orthologycellular process involved in reproduction in multicellular organism FBgn0013765
GO:0030997
IEA
PLAZA Integrative Orthologyregulation of centriole-centriole cohesion FBgn0013765
GO:0046530
IEA
PLAZA Integrative Orthologyphotoreceptor cell differentiation FBgn0013765
GO:0098722
IEA
PLAZA Integrative Orthologyasymmetric stem cell division FBgn0013765
GO:0045165
IEA
PLAZA Integrative Orthologycell fate commitment FBgn0013765

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0044212
IDA
Genome Projecttranscription regulatory region DNA binding
GO:0044212
IDA
Gene Ontologytranscription regulatory region DNA binding1
GO:0019901
IPI
Genome Projectprotein kinase binding
GO:0019901
IPI
Gene Ontologyprotein kinase binding2
GO:0015631
IPI
Genome Projecttubulin binding
GO:0015631
IPI
Gene Ontologytubulin binding8
GO:0008017
IDA
Genome Projectmicrotubule binding
GO:0008017
IDA
Gene Ontologymicrotubule binding10
GO:0005516
IEA
Genome Projectcalmodulin binding
GO:0005516
IDA
Gene Ontologycalmodulin binding11
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 3 5 7 8 9 11 12 13
GO:0043015
IDA
Gene Ontologygamma-tubulin binding9

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0097431
IEA
Genome Projectmitotic spindle pole
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0070062
Gene Ontologyextracellular exosome14
GO:0048471
IDA
Genome Projectperinuclear region of cytoplasm
GO:0048471
IDA
Gene Ontologyperinuclear region of cytoplasm8
GO:0035371
IDA
Genome Projectmicrotubule plus-end
GO:0035371
IDA
Gene Ontologymicrotubule plus-end3
GO:0030054
IDA
Genome Projectcell junction
GO:0030054
IDA
Gene Ontologycell junction
GO:0005874
IDA
Genome Projectmicrotubule
GO:0005874
IDA
Gene Ontologymicrotubule7
GO:0005856
NAS
Genome Projectcytoskeleton
GO:0005856
NAS
Gene Ontologycytoskeleton2
GO:0005829
TAS
Genome Projectcytosol
GO:0005829
TAS
Gene Ontologycytosol
GO:0005813
IDA
Genome Projectcentrosome
GO:0005813
IDA
Gene Ontologycentrosome1 3 6 7 8 9 10 11 15 16 17
GO:0005794
IDA
Genome ProjectGolgi apparatus
GO:0005794
IDA
Gene OntologyGolgi apparatus11
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005737
IDA
Gene Ontologycytoplasm1 7 8
GO:0000922
IDA
Genome Projectspindle pole
GO:0000922
IDA
Gene Ontologyspindle pole1 8
GO:0000242
IDA
Genome Projectpericentriolar material
GO:0000242
IDA
Gene Ontologypericentriolar material8
GO:0008274
IDA
Gene Ontologygamma-tubulin ring complex9
GO:0005814
IEA
PLAZA Integrative Orthologycentriole FBgn0013765

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR012943Centrosomin, N-terminal motif 1

No MapMan annotations defined for this gene.
KeggID Description
K16542CDK5RAP2; CDK5 regulatory subunit-associated protein 2
No chloroplast target sequence found.