Gene: ENSG00000136856 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000136856
Transcript Identifier
ENST00000373371
Gene Type
Coding gene
Location
9 : 127397231-127407249 : positive

Family Information

Homologous gene family
HOM02SEM000042
(378 genes in 26 species)
specific family

Descriptions

gene_descr
solute carrier family 2 (facilitated glucose transporter), member 8

Identifiers

Type Value
pidENSP00000362469
HGNC13812
UniprotQ9NY64
UniprotA0A024R871
RefSeq_mRNANM_014580.4
EMBLAJ245937
EMBLAL445222
EMBLBC019043
EMBLCH471090
EMBLY17801

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1904659
IEA
Genome Projectglucose transmembrane transport
GO:0061024
TAS
Genome Projectmembrane organization
GO:0061024
TAS
Gene Ontologymembrane organization
GO:0046323
IBA
Genome Projectglucose import
GO:0008286
IEA
Genome Projectinsulin receptor signaling pathway
GO:0007141
IEA
Genome Projectmale meiosis I
GO:0005975
TAS
Genome Projectcarbohydrate metabolic process
GO:0005975
TAS
Gene Ontologycarbohydrate metabolic process1
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0008645
TAS
Gene Ontologyhexose transmembrane transport
GO:0015791
IEA
PLAZA Integrative Orthologypolyol transport SPAC4F8.15
GO:0009791
IEA
PLAZA Integrative Orthologypost-embryonic development AT1G75220
GO:0048878
IEA
PLAZA Integrative Orthologychemical homeostasis AT1G75220
GO:0051094
IEA
PLAZA Integrative Orthologypositive regulation of developmental process AT1G75220
GO:0048518
IEA
PLAZA Integrative Orthologypositive regulation of biological process AT1G75220
GO:0007259
IEA
PLAZA Integrative OrthologyJAK-STAT cascade FBgn0036316
GO:0050793
IEA
PLAZA Integrative Orthologyregulation of developmental process AT1G75220
GO:0048522
IEA
PLAZA Integrative Orthologypositive regulation of cellular process FBgn0036316
GO:0051240
IEA
PLAZA Integrative Orthologypositive regulation of multicellular organismal process AT1G75220
GO:0098739
IEA
PLAZA Integrative Orthologyimport across plasma membrane SPAC4F8.15
GO:0035556
IEA
PLAZA Integrative Orthologyintracellular signal transduction FBgn0036316
GO:0070838
IEA
PLAZA Integrative Orthologydivalent metal ion transport AT2G48020
GO:0010030
IEA
PLAZA Integrative Orthologypositive regulation of seed germination AT1G75220
GO:0065008
IEA
PLAZA Integrative Orthologyregulation of biological quality AT1G75220
GO:1900140
IEA
PLAZA Integrative Orthologyregulation of seedling development AT1G75220
GO:0006970
IEA
PLAZA Integrative Orthologyresponse to osmotic stress AT5G26340
GO:0009967
IEA
PLAZA Integrative Orthologypositive regulation of signal transduction FBgn0036316
GO:0009845
IEA
PLAZA Integrative Orthologyseed germination AT1G75220
GO:0009966
IEA
PLAZA Integrative Orthologyregulation of signal transduction FBgn0036316
GO:0023056
IEA
PLAZA Integrative Orthologypositive regulation of signaling FBgn0036316
GO:0023051
IEA
PLAZA Integrative Orthologyregulation of signaling FBgn0036316
GO:0010029
IEA
PLAZA Integrative Orthologyregulation of seed germination AT1G75220
GO:0015798
IEA
PLAZA Integrative Orthologymyo-inositol transport SPAC4F8.15
GO:0015772
IEA
PLAZA Integrative Orthologyoligosaccharide transport FBgn0050035
GO:0009651
IEA
PLAZA Integrative Orthologyresponse to salt stress AT5G26340
GO:0015771
IEA
PLAZA Integrative Orthologytrehalose transport FBgn0050035
GO:0015770
IEA
PLAZA Integrative Orthologysucrose transport FBgn0050035
GO:0051707
IEA
PLAZA Integrative Orthologyresponse to other organism AT5G27350
GO:0009415
IEA
PLAZA Integrative Orthologyresponse to water AT5G26340
GO:0009414
IEA
PLAZA Integrative Orthologyresponse to water deprivation AT5G26340
GO:0006811
IEA
PLAZA Integrative Orthologyion transport AT2G48020
GO:0006812
IEA
PLAZA Integrative Orthologycation transport AT2G48020
GO:0016192
IEA
PLAZA Integrative Orthologyvesicle-mediated transport FBgn0037485
GO:0000041
IEA
PLAZA Integrative Orthologytransition metal ion transport AT2G48020
GO:0033993
IEA
PLAZA Integrative Orthologyresponse to lipid AT5G26340
GO:0030001
IEA
PLAZA Integrative Orthologymetal ion transport AT2G48020
GO:0015768
IEA
PLAZA Integrative Orthologymaltose transport FBgn0050035
GO:0015767
IEA
PLAZA Integrative Orthologylactose transport FBgn0050035
GO:0015766
IEA
PLAZA Integrative Orthologydisaccharide transport FBgn0050035
GO:0006829
IEA
PLAZA Integrative Orthologyzinc ion transport AT2G48020
GO:0010647
IEA
PLAZA Integrative Orthologypositive regulation of cell communication FBgn0036316
GO:0033500
IEA
PLAZA Integrative Orthologycarbohydrate homeostasis AT1G75220
GO:0010646
IEA
PLAZA Integrative Orthologyregulation of cell communication FBgn0036316
GO:0072511
IEA
PLAZA Integrative Orthologydivalent inorganic cation transport AT2G48020
GO:2000026
IEA
PLAZA Integrative Orthologyregulation of multicellular organismal development AT1G75220
GO:1904892
IEA
PLAZA Integrative Orthologyregulation of STAT cascade FBgn0036316
GO:1904894
IEA
PLAZA Integrative Orthologypositive regulation of STAT cascade FBgn0036316
GO:0098657
IEA
PLAZA Integrative Orthologyimport into cell SPAC4F8.15
GO:0015761
IEA
PLAZA Integrative Orthologymannose transmembrane transport YHR094C
GO:0046425
IEA
PLAZA Integrative Orthologyregulation of JAK-STAT cascade FBgn0036316
GO:0006897
IEA
PLAZA Integrative Orthologyendocytosis FBgn0037485
GO:0046427
IEA
PLAZA Integrative Orthologypositive regulation of JAK-STAT cascade FBgn0036316
GO:0097696
IEA
PLAZA Integrative OrthologySTAT cascade FBgn0036316
GO:0042592
IEA
PLAZA Integrative Orthologyhomeostatic process AT1G75220
GO:0042593
IEA
PLAZA Integrative Orthologyglucose homeostasis AT1G75220
GO:0098704
IEA
PLAZA Integrative Orthologycarbohydrate import across plasma membrane SPAC4F8.15
GO:0043207
IEA
PLAZA Integrative Orthologyresponse to external biotic stimulus AT5G27350
GO:0015850
IEA
PLAZA Integrative Orthologyorganic hydroxy compound transport SPAC4F8.15
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development AT1G75220
GO:1902531
IEA
PLAZA Integrative Orthologyregulation of intracellular signal transduction FBgn0036316
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development AT1G75220
GO:0090351
IEA
PLAZA Integrative Orthologyseedling development AT1G75220
GO:1904679
IEA
PLAZA Integrative Orthologymyo-inositol import across plasma membrane SPAC4F8.15
GO:1902533
IEA
PLAZA Integrative Orthologypositive regulation of intracellular signal transduction FBgn0036316
GO:0048584
IEA
PLAZA Integrative Orthologypositive regulation of response to stimulus FBgn0036316
GO:0009607
IEA
PLAZA Integrative Orthologyresponse to biotic stimulus AT5G27350
GO:0048583
IEA
PLAZA Integrative Orthologyregulation of response to stimulus FBgn0036316
GO:0048582
IEA
PLAZA Integrative Orthologypositive regulation of post-embryonic development AT1G75220
GO:0009605
IEA
PLAZA Integrative Orthologyresponse to external stimulus AT5G27350
GO:0097305
IEA
PLAZA Integrative Orthologyresponse to alcohol AT5G26340
GO:0010035
IEA
PLAZA Integrative Orthologyresponse to inorganic substance AT5G26340
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process AT1G75220
GO:0048580
IEA
PLAZA Integrative Orthologyregulation of post-embryonic development AT1G75220
GO:0009624
IEA
PLAZA Integrative Orthologyresponse to nematode AT5G27350
GO:0001101
IEA
PLAZA Integrative Orthologyresponse to acid chemical AT5G26340
GO:0009737
IEA
PLAZA Integrative Orthologyresponse to abscisic acid AT5G26340
GO:0042493
IEA
PLAZA Integrative Orthologyresponse to drug AT1G08930
GO:0006909
IEA
PLAZA Integrative Orthologyphagocytosis FBgn0037485
GO:0010200
IEA
PLAZA Integrative Orthologyresponse to chitin AT1G08930
GO:0051239
IEA
PLAZA Integrative Orthologyregulation of multicellular organismal process AT1G75220

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0055056
TAS
Genome ProjectD-glucose transmembrane transporter activity
GO:0055056
TAS
Gene OntologyD-glucose transmembrane transporter activity
GO:0005536
IEA
Genome Projectglucose binding
GO:0005355
TAS
Genome Projectglucose transmembrane transporter activity
GO:0005351
IBA
Genome Projectcarbohydrate:proton symporter activity
GO:0072509
IEA
PLAZA Integrative Orthologydivalent inorganic cation transmembrane transporter activity AT2G48020
GO:0015157
IEA
PLAZA Integrative Orthologyoligosaccharide transmembrane transporter activity FBgn0050035
GO:0015154
IEA
PLAZA Integrative Orthologydisaccharide transmembrane transporter activity FBgn0050035
GO:0005354
IEA
PLAZA Integrative Orthologygalactose transmembrane transporter activity YJL219W
GO:0005353
IEA
PLAZA Integrative Orthologyfructose transmembrane transporter activity YJL214W
GO:0005356
IEA
PLAZA Integrative Orthologyglucose:proton symporter activity AT5G26340
GO:0022883
IEA
PLAZA Integrative Orthologyzinc efflux transmembrane transporter activity AT2G48020
GO:0009679
IEA
PLAZA Integrative Orthologyhexose:proton symporter activity AT5G26340
GO:0005358
IEA
PLAZA Integrative Orthologyhigh-affinity glucose:proton symporter activity AT5G26340
GO:0046583
IEA
PLAZA Integrative Orthologycation efflux transmembrane transporter activity AT2G48020
GO:0015562
IEA
PLAZA Integrative Orthologyefflux transmembrane transporter activity AT2G48020
GO:0046915
IEA
PLAZA Integrative Orthologytransition metal ion transmembrane transporter activity AT2G48020
GO:0046873
IEA
PLAZA Integrative Orthologymetal ion transmembrane transporter activity AT2G48020
GO:0015146
IEA
PLAZA Integrative Orthologypentose transmembrane transporter activity YHR092C
GO:0015574
IEA
PLAZA Integrative Orthologytrehalose transmembrane transporter activity FBgn0050035
GO:0005385
IEA
PLAZA Integrative Orthologyzinc ion transmembrane transporter activity AT2G48020
GO:0015578
IEA
PLAZA Integrative Orthologymannose transmembrane transporter activity YJL214W

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0030665
TAS
Genome Projectclathrin-coated vesicle membrane
GO:0030665
TAS
Gene Ontologyclathrin-coated vesicle membrane
GO:0008021
IEA
Genome Projectsynaptic vesicle
GO:0005887
IEA
Genome Projectintegral component of plasma membrane
GO:0005886
TAS
Genome Projectplasma membrane
GO:0005886
TAS
Gene Ontologyplasma membrane
GO:0005765
IDA
Genome Projectlysosomal membrane
GO:0005765
Gene Ontologylysosomal membrane2
GO:0044431
IEA
PLAZA Integrative OrthologyGolgi apparatus part AT1G79820
GO:0009705
IEA
PLAZA Integrative Orthologyplant-type vacuole membrane AT2G48020
GO:0005634
IEA
PLAZA Integrative Orthologynucleus AT1G11260
GO:0005911
IEA
PLAZA Integrative Orthologycell-cell junction AT5G26340
GO:0031984
IEA
PLAZA Integrative Orthologyorganelle subcompartment AT1G79820
GO:0009536
IEA
PLAZA Integrative Orthologyplastid AT2G48020
GO:0000329
IEA
PLAZA Integrative Orthologyfungal-type vacuole membrane SPAC4F8.15
GO:0000325
IEA
PLAZA Integrative Orthologyplant-type vacuole AT2G48020
GO:0000324
IEA
PLAZA Integrative Orthologyfungal-type vacuole SPAC4F8.15
GO:0000322
IEA
PLAZA Integrative Orthologystorage vacuole SPAC4F8.15
GO:0005794
IEA
PLAZA Integrative OrthologyGolgi apparatus SPAC4F8.15
GO:0009507
IEA
PLAZA Integrative Orthologychloroplast AT2G48020
GO:0009506
IEA
PLAZA Integrative Orthologyplasmodesma AT5G26340
GO:0120025
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection AT5G26250
GO:0098791
IEA
PLAZA Integrative OrthologyGolgi subcompartment AT1G79820
GO:0030054
IEA
PLAZA Integrative Orthologycell junction AT5G26340
GO:0042995
IEA
PLAZA Integrative Orthologycell projection AT5G26250
GO:0005802
IEA
PLAZA Integrative Orthologytrans-Golgi network AT1G79820
GO:0005768
IEA
PLAZA Integrative Orthologyendosome AT1G79820
GO:0055044
IEA
PLAZA Integrative Orthologysymplast AT5G26340
GO:0005783
IEA
PLAZA Integrative Orthologyendoplasmic reticulum AT1G08930
GO:0090406
IEA
PLAZA Integrative Orthologypollen tube AT5G26250

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003663Sugar/inositol transporter
IPR005828Major facilitator, sugar transporter-like
IPR005829Sugar transporter, conserved site
IPR020846Major facilitator superfamily domain

No MapMan annotations defined for this gene.
KeggID Description
K08145SLC2A8, GLUT8; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8
No chloroplast target sequence found.