Gene: ENSG00000135945 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000135945
Transcript Identifier
ENST00000258428
Gene Type
Coding gene
Location
2 : 99401241-99464975 : negative

Family Information

Homologous gene family
HOM02SEM002047
(32 genes in 25 species)
specific family

Descriptions

gene_descr
REV1, polymerase (DNA directed)

Identifiers

Type Value
pidENSP00000258428
HGNC14060
UniprotQ9UBZ9
RefSeq_mRNANM_016316.2
EMBLAB047646
EMBLAC018690
EMBLAF151538
EMBLAF206019
EMBLAF357886
EMBLAJ131720
EMBLAK002087

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0042276
TAS
Genome Projecterror-prone translesion synthesis
GO:0042276
TAS
Gene Ontologyerror-prone translesion synthesis1
GO:0019985
TAS
Genome Projecttranslesion synthesis
GO:0019985
TAS
Gene Ontologytranslesion synthesis
GO:0009411
IDA
Genome Projectresponse to UV
GO:0009411
IDA
Gene Ontologyresponse to UV1
GO:0006260
TAS
Genome ProjectDNA replication
GO:0006260
TAS
Gene OntologyDNA replication2
GO:0043504
IEA
PLAZA Integrative Orthologymitochondrial DNA repair SPBC1347.01c
GO:0006282
IEA
PLAZA Integrative Orthologyregulation of DNA repair FBgn0035150
GO:0080134
IEA
PLAZA Integrative Orthologyregulation of response to stress FBgn0035150
GO:0051052
IEA
PLAZA Integrative Orthologyregulation of DNA metabolic process FBgn0035150
GO:0080135
IEA
PLAZA Integrative Orthologyregulation of cellular response to stress FBgn0035150
GO:0000018
IEA
PLAZA Integrative Orthologyregulation of DNA recombination FBgn0035150
GO:0051171
IEA
PLAZA Integrative Orthologyregulation of nitrogen compound metabolic process FBgn0035150
GO:0050794
IEA
PLAZA Integrative Orthologyregulation of cellular process FBgn0035150
GO:0065007
IEA
PLAZA Integrative Orthologybiological regulation FBgn0035150
GO:2001020
IEA
PLAZA Integrative Orthologyregulation of response to DNA damage stimulus FBgn0035150
GO:0032042
IEA
PLAZA Integrative Orthologymitochondrial DNA metabolic process SPBC1347.01c
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization SPBC1347.01c
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis SPBC1347.01c
GO:0010224
IEA
PLAZA Integrative Orthologyresponse to UV-B AT5G44750
GO:0019219
IEA
PLAZA Integrative Orthologyregulation of nucleobase-containing compound metabolic process FBgn0035150
GO:0006302
IEA
PLAZA Integrative Orthologydouble-strand break repair FBgn0035150
GO:0048583
IEA
PLAZA Integrative Orthologyregulation of response to stimulus FBgn0035150
GO:2000779
IEA
PLAZA Integrative Orthologyregulation of double-strand break repair FBgn0035150
GO:0019222
IEA
PLAZA Integrative Orthologyregulation of metabolic process FBgn0035150
GO:0070987
IEA
PLAZA Integrative Orthologyerror-free translesion synthesis SPBC1347.01c
GO:0060255
IEA
PLAZA Integrative Orthologyregulation of macromolecule metabolic process FBgn0035150
GO:0000725
IEA
PLAZA Integrative Orthologyrecombinational repair FBgn0035150
GO:0000724
IEA
PLAZA Integrative Orthologydouble-strand break repair via homologous recombination FBgn0035150
GO:0006310
IEA
PLAZA Integrative OrthologyDNA recombination FBgn0035150
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization SPBC1347.01c
GO:0007005
IEA
PLAZA Integrative Orthologymitochondrion organization SPBC1347.01c
GO:0000002
IEA
PLAZA Integrative Orthologymitochondrial genome maintenance SPBC1347.01c
GO:0010569
IEA
PLAZA Integrative Orthologyregulation of double-strand break repair via homologous recombination FBgn0035150
GO:0050789
IEA
PLAZA Integrative Orthologyregulation of biological process FBgn0035150
GO:0080090
IEA
PLAZA Integrative Orthologyregulation of primary metabolic process FBgn0035150
GO:0031323
IEA
PLAZA Integrative Orthologyregulation of cellular metabolic process FBgn0035150

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0017125
TAS
Genome Projectdeoxycytidyl transferase activity
GO:0017125
TAS
Gene Ontologydeoxycytidyl transferase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 3 4
GO:0003684
IEA
Genome Projectdamaged DNA binding
GO:0003887
IEA
PLAZA Integrative OrthologyDNA-directed DNA polymerase activity AT5G44750
GO:0034061
IEA
PLAZA Integrative OrthologyDNA polymerase activity AT5G44750
GO:0140097
IEA
PLAZA Integrative Orthologycatalytic activity, acting on DNA AT5G44750

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005654
TAS
Gene Ontologynucleoplasm
GO:0090734
IEA
PLAZA Integrative Orthologysite of DNA damage SPBC1347.01c
GO:0015630
IEA
PLAZA Integrative Orthologymicrotubule cytoskeleton SPBC1347.01c
GO:0043228
IEA
PLAZA Integrative Orthologynon-membrane-bounded organelle SPBC1347.01c
GO:0043232
IEA
PLAZA Integrative Orthologyintracellular non-membrane-bounded organelle SPBC1347.01c
GO:0000228
IEA
PLAZA Integrative Orthologynuclear chromosome YOR346W
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part YOR346W
GO:0000785
IEA
PLAZA Integrative Orthologychromatin YOR346W
GO:0000790
IEA
PLAZA Integrative Orthologynuclear chromatin YOR346W
GO:0035861
IEA
PLAZA Integrative Orthologysite of double-strand break SPBC1347.01c
GO:0044454
IEA
PLAZA Integrative Orthologynuclear chromosome part YOR346W
GO:0005694
IEA
PLAZA Integrative Orthologychromosome SPBC1347.01c
GO:0005730
IEA
PLAZA Integrative Orthologynucleolus SPBC1347.01c
GO:0072686
IEA
PLAZA Integrative Orthologymitotic spindle SPBC1347.01c
GO:0044427
IEA
PLAZA Integrative Orthologychromosomal part SPBC1347.01c
GO:0005657
IEA
PLAZA Integrative Orthologyreplication fork YOR346W
GO:0005856
IEA
PLAZA Integrative Orthologycytoskeleton SPBC1347.01c
GO:0005737
IEA
PLAZA Integrative Orthologycytoplasm YOR346W
GO:0044430
IEA
PLAZA Integrative Orthologycytoskeletal part SPBC1347.01c
GO:0005739
IEA
PLAZA Integrative Orthologymitochondrion YOR346W
GO:0005819
IEA
PLAZA Integrative Orthologyspindle SPBC1347.01c

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001126UmuC domain
IPR001357BRCT domain
IPR012112DNA repair protein Rev1
IPR017961DNA polymerase, Y-family, little finger domain
IPR025527Domain of unknown function DUF4414
IPR031991DNA repair protein Rev1, C-terminal

No MapMan annotations defined for this gene.
KeggID Description
K03515REV1; DNA repair protein REV1 [EC:2.7.7.-]
No chloroplast target sequence found.