Gene: ENSG00000133265 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000133265
Transcript Identifier
ENST00000587922
Gene Type
Coding gene
Location
19 : 55262608-55279608 : negative

Family Information

Homologous gene family
HOM02SEM007719
(11 genes in 8 species)
specific family

Descriptions

gene_descr
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1

Identifiers

Type Value
pidENSP00000467574
HGNC24989
UniprotQ9NZL4
RefSeq_mRNANM_001297600.1

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0043086
IEA
Genome Projectnegative regulation of catalytic activity
GO:0032436
IDA
Genome Projectpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032436
IDA
Gene Ontologypositive regulation of proteasomal ubiquitin-dependent protein catabolic process1
GO:0031398
IDA
Genome Projectpositive regulation of protein ubiquitination
GO:0031398
IDA
Gene Ontologypositive regulation of protein ubiquitination1
GO:0006457
TAS
Genome Projectprotein folding
GO:0006457
TAS
Gene Ontologyprotein folding2
GO:0050896
IEA
PLAZA Integrative Orthologyresponse to stimulus AT3G09350
GO:0009628
IEA
PLAZA Integrative Orthologyresponse to abiotic stimulus AT3G09350
GO:0009408
IEA
PLAZA Integrative Orthologyresponse to heat AT3G09350
GO:0006950
IEA
PLAZA Integrative Orthologyresponse to stress AT3G09350
GO:0006970
IEA
PLAZA Integrative Orthologyresponse to osmotic stress AT3G09350
GO:0009651
IEA
PLAZA Integrative Orthologyresponse to salt stress AT3G09350
GO:0009266
IEA
PLAZA Integrative Orthologyresponse to temperature stimulus AT3G09350

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding3 4 5 6 7
GO:0004857
TAS
Genome Projectenzyme inhibitor activity
GO:0004857
TAS
Gene Ontologyenzyme inhibitor activity2
GO:0031625
IPI
Gene Ontologyubiquitin protein ligase binding8
GO:0030544
IEA
PLAZA Integrative OrthologyHsp70 protein binding AT3G09350
GO:0031072
IEA
PLAZA Integrative Orthologyheat shock protein binding AT3G09350

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005829
IEA
PLAZA Integrative Orthologycytosol SPBC3B9.01
GO:0043231
IEA
PLAZA Integrative Orthologyintracellular membrane-bounded organelle SPBC3B9.01
GO:0005737
IEA
PLAZA Integrative Orthologycytoplasm SPBC3B9.01
GO:0005634
IEA
PLAZA Integrative Orthologynucleus SPBC3B9.01
GO:0043227
IEA
PLAZA Integrative Orthologymembrane-bounded organelle SPBC3B9.01
GO:0005623
IEA
PLAZA Integrative Orthologycell SPBC3B9.01
GO:0005622
IEA
PLAZA Integrative Orthologyintracellular SPBC3B9.01
GO:0043226
IEA
PLAZA Integrative Orthologyorganelle SPBC3B9.01
GO:0044424
IEA
PLAZA Integrative Orthologyintracellular part SPBC3B9.01
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part SPBC3B9.01
GO:0044464
IEA
PLAZA Integrative Orthologycell part SPBC3B9.01
GO:0043229
IEA
PLAZA Integrative Orthologyintracellular organelle SPBC3B9.01

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR011989Armadillo-like helical
IPR013918Nucleotide exchange factor Fes1
IPR016024Armadillo-type fold

No MapMan annotations defined for this gene.
KeggID Description
K09562HSPBP1, FES1; hsp70-interacting protein
No chloroplast target sequence found.