Gene: ENSG00000133119 (Homo sapiens)

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Gene Identifier
ENSG00000133119
Transcript Identifier
ENST00000380071
Gene Type
Coding gene
Location
13 : 33818179-33836295 : positive

Family Information

Homologous gene family
HOM02SEM001937
(33 genes in 26 species)
specific family
Orthologous gene family
ORTHO02SEM002205
(31 genes in 26 species)
specific family

Descriptions

gene_descr
replication factor C (activator 1) 3, 38kDa

Identifiers

Type Value
pidENSP00000369411
HGNC9971
UniprotP40938
UniprotA0A024RDQ8
RefSeq_mRNANM_002915.3
EMBLCH471075

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1901796
TAS
Genome Projectregulation of signal transduction by p53 class mediator
GO:1900264
IDA
Genome Projectpositive regulation of DNA-directed DNA polymerase activity
GO:1900264
IDA
Gene Ontologypositive regulation of DNA-directed DNA polymerase activity1
GO:0070987
TAS
Genome Projecterror-free translesion synthesis
GO:0070987
TAS
Gene Ontologyerror-free translesion synthesis
GO:0046683
IEP
Genome Projectresponse to organophosphorus
GO:0046683
IEP
Gene Ontologyresponse to organophosphorus2
GO:0042769
TAS
Genome ProjectDNA damage response, detection of DNA damage
GO:0042769
TAS
Gene OntologyDNA damage response, detection of DNA damage
GO:0042276
TAS
Genome Projecterror-prone translesion synthesis
GO:0042276
TAS
Gene Ontologyerror-prone translesion synthesis
GO:0033683
TAS
Genome Projectnucleotide-excision repair, DNA incision
GO:0033683
TAS
Gene Ontologynucleotide-excision repair, DNA incision
GO:0019985
TAS
Genome Projecttranslesion synthesis
GO:0019985
TAS
Gene Ontologytranslesion synthesis
GO:0006297
TAS
Genome Projectnucleotide-excision repair, DNA gap filling
GO:0006297
TAS
Gene Ontologynucleotide-excision repair, DNA gap filling
GO:0006296
TAS
Genome Projectnucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006296
TAS
Gene Ontologynucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006283
TAS
Genome Projecttranscription-coupled nucleotide-excision repair
GO:0006283
TAS
Gene Ontologytranscription-coupled nucleotide-excision repair
GO:0006271
TAS
Genome ProjectDNA strand elongation involved in DNA replication
GO:0006271
TAS
Gene OntologyDNA strand elongation involved in DNA replication3
GO:0006260
IDA
TAS
Genome ProjectDNA replication
GO:0006260
IDA
TAS
Gene OntologyDNA replication4
GO:0000731
TAS
Genome ProjectDNA synthesis involved in DNA repair
GO:0000731
TAS
Gene OntologyDNA synthesis involved in DNA repair4
GO:0000722
TAS
Genome Projecttelomere maintenance via recombination
GO:0032201
TAS
Gene Ontologytelomere maintenance via semi-conservative replication
GO:0030154
IEA
PLAZA Integrative Orthologycell differentiation FBgn0028700
GO:0048869
IEA
PLAZA Integrative Orthologycellular developmental process FBgn0028700
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction AT5G27740
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process AT5G27740
GO:0006272
IEA
PLAZA Integrative Orthologyleading strand elongation YBR087W
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process AT5G27740
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process AT5G27740
GO:0071478
IEA
PLAZA Integrative Orthologycellular response to radiation SPBC83.14c
GO:0034644
IEA
PLAZA Integrative Orthologycellular response to UV SPBC83.14c
GO:0016070
IEA
PLAZA Integrative OrthologyRNA metabolic process YBR087W
GO:0009411
IEA
PLAZA Integrative Orthologyresponse to UV SPBC83.14c
GO:0009416
IEA
PLAZA Integrative Orthologyresponse to light stimulus SPBC83.14c
GO:0007399
IEA
PLAZA Integrative Orthologynervous system development FBgn0028700
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development AT5G27740
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development AT5G27740
GO:0104004
IEA
PLAZA Integrative Orthologycellular response to environmental stimulus SPBC83.14c
GO:0048731
IEA
PLAZA Integrative Orthologysystem development AT5G27740
GO:0071482
IEA
PLAZA Integrative Orthologycellular response to light stimulus SPBC83.14c
GO:0048608
IEA
PLAZA Integrative Orthologyreproductive structure development AT5G27740
GO:0070914
IEA
PLAZA Integrative OrthologyUV-damage excision repair SPBC83.14c
GO:0010154
IEA
PLAZA Integrative Orthologyfruit development AT5G27740
GO:0007062
IEA
PLAZA Integrative Orthologysister chromatid cohesion YBR087W
GO:0098813
IEA
PLAZA Integrative Orthologynuclear chromosome segregation YBR087W
GO:0071214
IEA
PLAZA Integrative Orthologycellular response to abiotic stimulus SPBC83.14c
GO:0009628
IEA
PLAZA Integrative Orthologyresponse to abiotic stimulus SPBC83.14c
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction AT5G27740
GO:0061458
IEA
PLAZA Integrative Orthologyreproductive system development AT5G27740
GO:0022008
IEA
PLAZA Integrative Orthologyneurogenesis FBgn0028700
GO:0007059
IEA
PLAZA Integrative Orthologychromosome segregation YBR087W
GO:0048316
IEA
PLAZA Integrative Orthologyseed development AT5G27740
GO:0009314
IEA
PLAZA Integrative Orthologyresponse to radiation SPBC83.14c
GO:0009791
IEA
PLAZA Integrative Orthologypost-embryonic development AT5G27740
GO:0009793
IEA
PLAZA Integrative Orthologyembryo development ending in seed dormancy AT5G27740
GO:0000819
IEA
PLAZA Integrative Orthologysister chromatid segregation YBR087W
GO:0009790
IEA
PLAZA Integrative Orthologyembryo development AT5G27740

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0043142
IDA
Genome Projectsingle-stranded DNA-dependent ATPase activity
GO:0043142
IDA
Gene Ontologysingle-stranded DNA-dependent ATPase activity1
GO:0016887
IDA
Genome ProjectATPase activity
GO:0016887
IDA
Gene OntologyATPase activity4
GO:0003689
IDA
TAS
Genome ProjectDNA clamp loader activity
GO:0003689
IDA
TAS
Gene OntologyDNA clamp loader activity1 4
GO:0003677
IDA
Genome ProjectDNA binding
GO:0003677
IDA
Gene OntologyDNA binding4
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding4
GO:0061860
IEA
PLAZA Integrative OrthologyDNA clamp unloader activity SPBC83.14c

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0031390
IDA
Genome ProjectCtf18 RFC-like complex
GO:0031390
IDA
Gene OntologyCtf18 RFC-like complex1
GO:0005663
IDA
TAS
Genome ProjectDNA replication factor C complex
GO:0005663
IDA
TAS
Gene OntologyDNA replication factor C complex3 4
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005654
TAS
Gene Ontologynucleoplasm
GO:0044430
IEA
PLAZA Integrative Orthologycytoskeletal part FBgn0028700
GO:0005737
IEA
PLAZA Integrative Orthologycytoplasm SPBC83.14c
GO:0005856
IEA
PLAZA Integrative Orthologycytoskeleton FBgn0028700
GO:1904949
IEA
PLAZA Integrative OrthologyATPase complex SPBC83.14c
GO:0044454
IEA
PLAZA Integrative Orthologynuclear chromosome part SPBC83.14c
GO:1902494
IEA
PLAZA Integrative Orthologycatalytic complex SPBC83.14c
GO:0031389
IEA
PLAZA Integrative OrthologyRad17 RFC-like complex YBR087W
GO:0000790
IEA
PLAZA Integrative Orthologynuclear chromatin SPBC83.14c
GO:0000785
IEA
PLAZA Integrative Orthologychromatin SPBC83.14c
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part SPBC83.14c
GO:0000228
IEA
PLAZA Integrative Orthologynuclear chromosome SPBC83.14c
GO:0043596
IEA
PLAZA Integrative Orthologynuclear replication fork SPBC83.14c
GO:0031391
IEA
PLAZA Integrative OrthologyElg1 RFC-like complex SPBC83.14c
GO:0005829
IEA
PLAZA Integrative Orthologycytosol SPBC83.14c
GO:0005875
IEA
PLAZA Integrative Orthologymicrotubule associated complex FBgn0028700
GO:0015630
IEA
PLAZA Integrative Orthologymicrotubule cytoskeleton FBgn0028700

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003593AAA+ ATPase domain
IPR008921DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.
KeggID Description
K10756RFC3_5; replication factor C subunit 3/5
No chloroplast target sequence found.