Gene: ENSG00000132932 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000132932
Transcript Identifier
ENST00000381655
Gene Type
Coding gene
Location
13 : 25372213-26019985 : positive

Family Information

Homologous gene family
HOM02SEM000141
(175 genes in 26 species)
specific family
Orthologous gene family
ORTHO02SEM000129
(164 genes in 26 species)
specific family

Descriptions

gene_descr
ATPase, aminophospholipid transporter, class I, type 8A, member 2

Identifiers

Type Value
pidENSP00000371070
HGNC13533
UniprotQ9NTI2
RefSeq_mRNANM_016529.4

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0061092
IEA
Genome Projectpositive regulation of phospholipid translocation
GO:0060052
IEA
Genome Projectneurofilament cytoskeleton organization
GO:0050908
IEA
Genome Projectdetection of light stimulus involved in visual perception
GO:0050884
IEA
Genome Projectneuromuscular process controlling posture
GO:0048666
IBA
Genome Projectneuron development
GO:0045332
IEA
Genome Projectphospholipid translocation
GO:0043588
IEA
Genome Projectskin development
GO:0042755
IEA
Genome Projecteating behavior
GO:0042472
IEA
Genome Projectinner ear morphogenesis
GO:0040018
IEA
Genome Projectpositive regulation of multicellular organism growth
GO:0010996
IEA
Genome Projectresponse to auditory stimulus
GO:0010976
IEA
Genome Projectpositive regulation of neuron projection development
GO:0010842
IEA
Genome Projectretina layer formation
GO:0008285
TAS
Genome Projectnegative regulation of cell proliferation
GO:0008285
TAS
Gene Ontologynegative regulation of cell proliferation1
GO:0007568
IEA
Genome Projectaging
GO:0007409
IEA
Genome Projectaxonogenesis
GO:0003011
IEA
Genome Projectinvoluntary skeletal muscle contraction
GO:0048193
IEA
PLAZA Integrative OrthologyGolgi vesicle transport AT1G59820
GO:0048194
IEA
PLAZA Integrative OrthologyGolgi vesicle budding AT1G59820
GO:0006909
IEA
PLAZA Integrative Orthologyphagocytosis WBGene00013034
GO:0006900
IEA
PLAZA Integrative Orthologyvesicle budding from membrane AT1G59820
GO:0048868
IEA
PLAZA Integrative Orthologypollen tube development AT3G13900
GO:0042886
IEA
PLAZA Integrative Orthologyamide transport YMR162C
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction AT3G13900
GO:0043299
IEA
PLAZA Integrative Orthologyleukocyte degranulation ENSG00000124406
GO:0009860
IEA
PLAZA Integrative Orthologypollen tube growth AT3G13900
GO:0044706
IEA
PLAZA Integrative Orthologymulti-multicellular organism process AT3G13900
GO:0044703
IEA
PLAZA Integrative Orthologymulti-organism reproductive process YMR162C
GO:0009856
IEA
PLAZA Integrative Orthologypollination AT3G13900
GO:0060627
IEA
PLAZA Integrative Orthologyregulation of vesicle-mediated transport WBGene00013034
GO:0044255
IEA
PLAZA Integrative Orthologycellular lipid metabolic process AT3G13900
GO:0010286
IEA
PLAZA Integrative Orthologyheat acclimation AT1G54280
GO:0016049
IEA
PLAZA Integrative Orthologycell growth AT3G13900
GO:0002446
IEA
PLAZA Integrative Orthologyneutrophil mediated immunity ENSG00000124406
GO:0002444
IEA
PLAZA Integrative Orthologymyeloid leukocyte mediated immunity ENSG00000124406
GO:0000028
IEA
PLAZA Integrative Orthologyribosomal small subunit assembly YAL026C
GO:0070887
IEA
PLAZA Integrative Orthologycellular response to chemical stimulus YMR162C
GO:0030100
IEA
PLAZA Integrative Orthologyregulation of endocytosis WBGene00013034
GO:0098657
IEA
PLAZA Integrative Orthologyimport into cell YAL026C
GO:0016050
IEA
PLAZA Integrative Orthologyvesicle organization AT1G59820
GO:0006911
IEA
PLAZA Integrative Orthologyphagocytosis, engulfment WBGene00013034
GO:0002443
IEA
PLAZA Integrative Orthologyleukocyte mediated immunity ENSG00000124406
GO:0044237
IEA
PLAZA Integrative Orthologycellular metabolic process AT3G13900
GO:0044238
IEA
PLAZA Integrative Orthologyprimary metabolic process AT3G13900
GO:0022607
IEA
PLAZA Integrative Orthologycellular component assembly YAL026C
GO:0051716
IEA
PLAZA Integrative Orthologycellular response to stimulus YMR162C
GO:0001775
IEA
PLAZA Integrative Orthologycell activation ENSG00000124406
GO:0009266
IEA
PLAZA Integrative Orthologyresponse to temperature stimulus AT1G54280
GO:0055085
IEA
PLAZA Integrative Orthologytransmembrane transport ENSG00000124406
GO:0060099
IEA
PLAZA Integrative Orthologyregulation of phagocytosis, engulfment WBGene00013034
GO:0032940
IEA
PLAZA Integrative Orthologysecretion by cell ENSG00000124406
GO:0051704
IEA
PLAZA Integrative Orthologymulti-organism process AT3G13900
GO:0099402
IEA
PLAZA Integrative Orthologyplant organ development AT1G59820
GO:0071310
IEA
PLAZA Integrative Orthologycellular response to organic substance YMR162C
GO:0009932
IEA
PLAZA Integrative Orthologycell tip growth AT3G13900
GO:0015833
IEA
PLAZA Integrative Orthologypeptide transport YMR162C
GO:0034220
IEA
PLAZA Integrative Orthologyion transmembrane transport ENSG00000124406
GO:0046907
IEA
PLAZA Integrative Orthologyintracellular transport YMR162C
GO:0046903
IEA
PLAZA Integrative Orthologysecretion ENSG00000124406
GO:0010033
IEA
PLAZA Integrative Orthologyresponse to organic substance YMR162C
GO:0051129
IEA
PLAZA Integrative Orthologynegative regulation of cellular component organization WBGene00013034
GO:0009826
IEA
PLAZA Integrative Orthologyunidimensional cell growth AT3G13900
GO:0015031
IEA
PLAZA Integrative Orthologyprotein transport YMR162C
GO:0045807
IEA
PLAZA Integrative Orthologypositive regulation of endocytosis WBGene00013034
GO:0045806
IEA
PLAZA Integrative Orthologynegative regulation of endocytosis WBGene00013034
GO:0032456
IEA
PLAZA Integrative Orthologyendocytic recycling YAL026C
GO:0010324
IEA
PLAZA Integrative Orthologymembrane invagination WBGene00013034
GO:0006629
IEA
PLAZA Integrative Orthologylipid metabolic process AT3G13900
GO:0002275
IEA
PLAZA Integrative Orthologymyeloid cell activation involved in immune response ENSG00000124406
GO:0002274
IEA
PLAZA Integrative Orthologymyeloid leukocyte activation ENSG00000124406
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process AT3G13900
GO:0007040
IEA
PLAZA Integrative Orthologylysosome organization WBGene00013034
GO:0031137
IEA
PLAZA Integrative Orthologyregulation of conjugation with cellular fusion YMR162C
GO:0031136
IEA
PLAZA Integrative Orthologypositive regulation of conjugation YMR162C
GO:0031139
IEA
PLAZA Integrative Orthologypositive regulation of conjugation with cellular fusion YMR162C
GO:0048588
IEA
PLAZA Integrative Orthologydevelopmental cell growth AT3G13900
GO:0002263
IEA
PLAZA Integrative Orthologycell activation involved in immune response ENSG00000124406
GO:0007033
IEA
PLAZA Integrative Orthologyvacuole organization WBGene00013034
GO:0060101
IEA
PLAZA Integrative Orthologynegative regulation of phagocytosis, engulfment WBGene00013034
GO:0060100
IEA
PLAZA Integrative Orthologypositive regulation of phagocytosis, engulfment WBGene00013034
GO:0042119
IEA
PLAZA Integrative Orthologyneutrophil activation ENSG00000124406
GO:0050765
IEA
PLAZA Integrative Orthologynegative regulation of phagocytosis WBGene00013034
GO:0050764
IEA
PLAZA Integrative Orthologyregulation of phagocytosis WBGene00013034
GO:0050766
IEA
PLAZA Integrative Orthologypositive regulation of phagocytosis WBGene00013034
GO:0019953
IEA
PLAZA Integrative Orthologysexual reproduction YMR162C
GO:0071444
IEA
PLAZA Integrative Orthologycellular response to pheromone YMR162C
GO:0045184
IEA
PLAZA Integrative Orthologyestablishment of protein localization YMR162C
GO:0006897
IEA
PLAZA Integrative Orthologyendocytosis YAL026C
GO:0006892
IEA
PLAZA Integrative Orthologypost-Golgi vesicle-mediated transport YAL026C
GO:0043312
IEA
PLAZA Integrative Orthologyneutrophil degranulation ENSG00000124406
GO:0044764
IEA
PLAZA Integrative Orthologymulti-organism cellular process YMR162C
GO:0042221
IEA
PLAZA Integrative Orthologyresponse to chemical YMR162C
GO:0008152
IEA
PLAZA Integrative Orthologymetabolic process AT3G13900
GO:0045055
IEA
PLAZA Integrative Orthologyregulated exocytosis ENSG00000124406
GO:0044085
IEA
PLAZA Integrative Orthologycellular component biogenesis YAL026C
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction AT3G13900
GO:0006643
IEA
PLAZA Integrative Orthologymembrane lipid metabolic process AT3G13900
GO:0006887
IEA
PLAZA Integrative Orthologyexocytosis ENSG00000124406
GO:0006886
IEA
PLAZA Integrative Orthologyintracellular protein transport YMR162C
GO:0002283
IEA
PLAZA Integrative Orthologyneutrophil activation involved in immune response ENSG00000124406
GO:0051051
IEA
PLAZA Integrative Orthologynegative regulation of transport WBGene00013034
GO:0060560
IEA
PLAZA Integrative Orthologydevelopmental growth involved in morphogenesis AT3G13900
GO:0070925
IEA
PLAZA Integrative Orthologyorganelle assembly YAL026C
GO:0080171
IEA
PLAZA Integrative Orthologylytic vacuole organization WBGene00013034
GO:0031323
IEA
PLAZA Integrative Orthologyregulation of cellular metabolic process AT3G13900
GO:0080090
IEA
PLAZA Integrative Orthologyregulation of primary metabolic process AT3G13900
GO:0071704
IEA
PLAZA Integrative Orthologyorganic substance metabolic process AT3G13900
GO:0019216
IEA
PLAZA Integrative Orthologyregulation of lipid metabolic process AT3G13900
GO:0045321
IEA
PLAZA Integrative Orthologyleukocyte activation ENSG00000124406
GO:0006950
IEA
PLAZA Integrative Orthologyresponse to stress AT1G54280
GO:0022613
IEA
PLAZA Integrative Orthologyribonucleoprotein complex biogenesis YAL026C
GO:0022618
IEA
PLAZA Integrative Orthologyribonucleoprotein complex assembly YAL026C
GO:0071826
IEA
PLAZA Integrative Orthologyribonucleoprotein complex subunit organization YAL026C
GO:0071705
IEA
PLAZA Integrative Orthologynitrogen compound transport YMR162C
GO:0043933
IEA
PLAZA Integrative Orthologyprotein-containing complex subunit organization YAL026C
GO:0140253
IEA
PLAZA Integrative Orthologycell-cell fusion YMR162C
GO:0019222
IEA
PLAZA Integrative Orthologyregulation of metabolic process AT3G13900
GO:0016197
IEA
PLAZA Integrative Orthologyendosomal transport YAL026C
GO:0016192
IEA
PLAZA Integrative Orthologyvesicle-mediated transport AT1G59820
GO:0009408
IEA
PLAZA Integrative Orthologyresponse to heat AT1G54280
GO:0046999
IEA
PLAZA Integrative Orthologyregulation of conjugation YMR162C
GO:0022622
IEA
PLAZA Integrative Orthologyroot system development AT1G59820
GO:0036230
IEA
PLAZA Integrative Orthologygranulocyte activation ENSG00000124406
GO:0034613
IEA
PLAZA Integrative Orthologycellular protein localization YMR162C
GO:2000243
IEA
PLAZA Integrative Orthologypositive regulation of reproductive process YMR162C
GO:0019236
IEA
PLAZA Integrative Orthologyresponse to pheromone YMR162C
GO:0042274
IEA
PLAZA Integrative Orthologyribosomal small subunit biogenesis YAL026C
GO:0002376
IEA
PLAZA Integrative Orthologyimmune system process ENSG00000124406
GO:0002252
IEA
PLAZA Integrative Orthologyimmune effector process ENSG00000124406
GO:0000746
IEA
PLAZA Integrative Orthologyconjugation YMR162C
GO:0000747
IEA
PLAZA Integrative Orthologyconjugation with cellular fusion YMR162C
GO:0000749
IEA
PLAZA Integrative Orthologyresponse to pheromone triggering conjugation with cellular fusion YMR162C
GO:1905038
IEA
PLAZA Integrative Orthologyregulation of membrane lipid metabolic process AT3G13900
GO:0065003
IEA
PLAZA Integrative Orthologyprotein-containing complex assembly YAL026C
GO:1905153
IEA
PLAZA Integrative Orthologyregulation of membrane invagination WBGene00013034
GO:1905154
IEA
PLAZA Integrative Orthologynegative regulation of membrane invagination WBGene00013034
GO:1905155
IEA
PLAZA Integrative Orthologypositive regulation of membrane invagination WBGene00013034
GO:0051649
IEA
PLAZA Integrative Orthologyestablishment of localization in cell YMR162C
GO:0034622
IEA
PLAZA Integrative Orthologycellular protein-containing complex assembly YAL026C
GO:0048367
IEA
PLAZA Integrative Orthologyshoot system development AT1G59820
GO:0006955
IEA
PLAZA Integrative Orthologyimmune response ENSG00000124406
GO:0051641
IEA
PLAZA Integrative Orthologycellular localization YMR162C
GO:0099024
IEA
PLAZA Integrative Orthologyplasma membrane invagination WBGene00013034
GO:0048364
IEA
PLAZA Integrative Orthologyroot development AT1G59820
GO:0002366
IEA
PLAZA Integrative Orthologyleukocyte activation involved in immune response ENSG00000124406
GO:0042255
IEA
PLAZA Integrative Orthologyribosome assembly YAL026C
GO:0042254
IEA
PLAZA Integrative Orthologyribosome biogenesis YAL026C
GO:0008104
IEA
PLAZA Integrative Orthologyprotein localization YMR162C
GO:2000241
IEA
PLAZA Integrative Orthologyregulation of reproductive process YMR162C
GO:0070727
IEA
PLAZA Integrative Orthologycellular macromolecule localization YMR162C
GO:0043902
IEA
PLAZA Integrative Orthologypositive regulation of multi-organism process YMR162C
GO:0043900
IEA
PLAZA Integrative Orthologyregulation of multi-organism process YMR162C

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005524
IEA
Genome ProjectATP binding
GO:0004012
IBA
Genome Projectphospholipid-translocating ATPase activity
GO:0000287
IEA
Genome Projectmagnesium ion binding
GO:0046914
IEA
PLAZA Integrative Orthologytransition metal ion binding AT1G54280
GO:0008270
IEA
PLAZA Integrative Orthologyzinc ion binding AT1G54280
GO:0005515
IEA
PLAZA Integrative Orthologyprotein binding AT5G04930

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0005886
IDA
Genome Projectplasma membrane
GO:0005886
IDA
Gene Ontologyplasma membrane2
GO:0005794
IDA
Genome ProjectGolgi apparatus
GO:0005794
IDA
Gene OntologyGolgi apparatus2
GO:0005768
IEA
Genome Projectendosome
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005654
IDA
Gene Ontologynucleoplasm
GO:0001750
IEA
Genome Projectphotoreceptor outer segment
GO:0031520
IEA
PLAZA Integrative Orthologyplasma membrane of cell tip YMR162C
GO:0005937
IEA
PLAZA Integrative Orthologymating projection YMR162C
GO:0031090
IEA
PLAZA Integrative Orthologyorganelle membrane ENSG00000124406
GO:0055044
IEA
PLAZA Integrative Orthologysymplast AT5G44240
GO:0035579
IEA
PLAZA Integrative Orthologyspecific granule membrane ENSG00000124406
GO:0035577
IEA
PLAZA Integrative Orthologyazurophil granule membrane ENSG00000124406
GO:0005802
IEA
PLAZA Integrative Orthologytrans-Golgi network AT1G59820
GO:1902494
IEA
PLAZA Integrative Orthologycatalytic complex YAL026C
GO:0032991
IEA
PLAZA Integrative Orthologyprotein-containing complex YAL026C
GO:0009526
IEA
PLAZA Integrative Orthologyplastid envelope AT1G26130
GO:0098791
IEA
PLAZA Integrative OrthologyGolgi subcompartment AT1G59820
GO:0099503
IEA
PLAZA Integrative Orthologysecretory vesicle ENSG00000124406
GO:0009506
IEA
PLAZA Integrative Orthologyplasmodesma AT5G44240
GO:0009507
IEA
PLAZA Integrative Orthologychloroplast AT1G26130
GO:1903561
IEA
PLAZA Integrative Orthologyextracellular vesicle ENSG00000124406
GO:0031967
IEA
PLAZA Integrative Orthologyorganelle envelope AT1G26130
GO:0000323
IEA
PLAZA Integrative Orthologylytic vacuole ENSG00000124406
GO:0009941
IEA
PLAZA Integrative Orthologychloroplast envelope AT1G26130
GO:0031975
IEA
PLAZA Integrative Orthologyenvelope AT1G26130
GO:0005576
IEA
PLAZA Integrative Orthologyextracellular region ENSG00000124406
GO:0031984
IEA
PLAZA Integrative Orthologyorganelle subcompartment AT1G59820
GO:0098588
IEA
PLAZA Integrative Orthologybounding membrane of organelle ENSG00000124406
GO:0005911
IEA
PLAZA Integrative Orthologycell-cell junction AT5G44240
GO:0030659
IEA
PLAZA Integrative Orthologycytoplasmic vesicle membrane ENSG00000124406
GO:0098590
IEA
PLAZA Integrative Orthologyplasma membrane region YMR162C
GO:0030427
IEA
PLAZA Integrative Orthologysite of polarized growth YMR162C
GO:0030667
IEA
PLAZA Integrative Orthologysecretory granule membrane ENSG00000124406
GO:0098805
IEA
PLAZA Integrative Orthologywhole membrane ENSG00000124406
GO:0012506
IEA
PLAZA Integrative Orthologyvesicle membrane ENSG00000124406
GO:0005783
IEA
PLAZA Integrative Orthologyendoplasmic reticulum SPBC887.12
GO:0044421
IEA
PLAZA Integrative Orthologyextracellular region part ENSG00000124406
GO:0043332
IEA
PLAZA Integrative Orthologymating projection tip YMR162C
GO:1904949
IEA
PLAZA Integrative OrthologyATPase complex YAL026C
GO:0005887
IEA
PLAZA Integrative Orthologyintegral component of plasma membrane WBGene00013034
GO:0005766
IEA
PLAZA Integrative Orthologyprimary lysosome ENSG00000124406
GO:1990351
IEA
PLAZA Integrative Orthologytransporter complex YAL026C
GO:0005773
IEA
PLAZA Integrative Orthologyvacuole ENSG00000124406
GO:0005774
IEA
PLAZA Integrative Orthologyvacuolar membrane ENSG00000124406
GO:0016324
IEA
PLAZA Integrative Orthologyapical plasma membrane WBGene00013034
GO:0016323
IEA
PLAZA Integrative Orthologybasolateral plasma membrane WBGene00013034
GO:0030054
IEA
PLAZA Integrative Orthologycell junction AT5G44240
GO:0042582
IEA
PLAZA Integrative Orthologyazurophil granule ENSG00000124406
GO:0042581
IEA
PLAZA Integrative Orthologyspecific granule ENSG00000124406
GO:0045177
IEA
PLAZA Integrative Orthologyapical part of cell WBGene00013034
GO:0051286
IEA
PLAZA Integrative Orthologycell tip YMR162C
GO:0005798
IEA
PLAZA Integrative OrthologyGolgi-associated vesicle YMR162C
GO:0005615
IEA
PLAZA Integrative Orthologyextracellular space ENSG00000124406
GO:0070867
IEA
PLAZA Integrative Orthologymating projection tip membrane YMR162C
GO:0070062
IEA
PLAZA Integrative Orthologyextracellular exosome ENSG00000124406
GO:0044459
IEA
PLAZA Integrative Orthologyplasma membrane part YMR162C
GO:0009536
IEA
PLAZA Integrative Orthologyplastid AT1G26130
GO:0030135
IEA
PLAZA Integrative Orthologycoated vesicle YMR162C
GO:0031226
IEA
PLAZA Integrative Orthologyintrinsic component of plasma membrane WBGene00013034
GO:0030136
IEA
PLAZA Integrative Orthologyclathrin-coated vesicle YMR162C
GO:0030133
IEA
PLAZA Integrative Orthologytransport vesicle YMR162C
GO:1990531
IEA
PLAZA Integrative Orthologyphospholipid-translocating ATPase complex YAL026C
GO:1990530
IEA
PLAZA Integrative OrthologyCdc50p-Drs2p complex YAL026C
GO:0005764
IEA
PLAZA Integrative Orthologylysosome ENSG00000124406
GO:0005765
IEA
PLAZA Integrative Orthologylysosomal membrane ENSG00000124406
GO:0030140
IEA
PLAZA Integrative Orthologytrans-Golgi network transport vesicle YMR162C
GO:0030141
IEA
PLAZA Integrative Orthologysecretory granule ENSG00000124406
GO:0043230
IEA
PLAZA Integrative Orthologyextracellular organelle ENSG00000124406
GO:0098852
IEA
PLAZA Integrative Orthologylytic vacuole membrane ENSG00000124406
GO:0044437
IEA
PLAZA Integrative Orthologyvacuolar part ENSG00000124406
GO:0044435
IEA
PLAZA Integrative Orthologyplastid part AT1G26130
GO:0044433
IEA
PLAZA Integrative Orthologycytoplasmic vesicle part ENSG00000124406
GO:0044434
IEA
PLAZA Integrative Orthologychloroplast part AT1G26130
GO:0044431
IEA
PLAZA Integrative OrthologyGolgi apparatus part AT1G59820

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001757P-type ATPase
IPR006539P-type ATPase, subfamily IV
IPR008250P-type ATPase, A domain superfamily
IPR018303P-type ATPase, phosphorylation site
IPR023214HAD superfamily
IPR023298P-type ATPase, transmembrane domain superfamily
IPR023299P-type ATPase, cytoplasmic domain N
IPR032630P-type ATPase, C-terminal
IPR032631P-type ATPase, N-terminal

No MapMan annotations defined for this gene.
KeggID Description
K14802DRS2, ATP8A; phospholipid-transporting ATPase [EC:7.6.2.1]
No chloroplast target sequence found.