Gene: ENSG00000131914 (Homo sapiens)

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Gene Identifier
ENSG00000131914
Transcript Identifier
ENST00000254231
Gene Type
Coding gene
Location
1 : 26410892-26426458 : positive

Family Information

Homologous gene family
HOM02SEM000623
(66 genes in 19 species)
specific family

Descriptions

gene_descr
lin-28 homolog A (C. elegans)

Identifiers

Type Value
pidENSP00000254231
HGNC15986
UniprotQ9H9Z2

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1903800
ISS
Genome Projectpositive regulation of production of miRNAs involved in gene silencing by miRNA
GO:1903800
ISS
Gene Ontologypositive regulation of production of miRNAs involved in gene silencing by miRNA
GO:1901724
IEA
Genome Projectpositive regulation of cell proliferation involved in kidney development
GO:0071333
ISS
Genome Projectcellular response to glucose stimulus
GO:0071333
ISS
Gene Ontologycellular response to glucose stimulus
GO:0051897
ISS
Genome Projectpositive regulation of protein kinase B signaling
GO:0051897
ISS
Gene Ontologypositive regulation of protein kinase B signaling
GO:0048863
IEA
Genome Projectstem cell differentiation
GO:0045727
IEA
Genome Projectpositive regulation of translation
GO:0045686
IEA
Genome Projectnegative regulation of glial cell differentiation
GO:0045666
IEA
Genome Projectpositive regulation of neuron differentiation
GO:0035019
TAS
Genome Projectsomatic stem cell population maintenance
GO:0035019
TAS
Gene Ontologysomatic stem cell population maintenance
GO:0032008
ISS
Genome Projectpositive regulation of TOR signaling
GO:0032008
ISS
Gene Ontologypositive regulation of TOR signaling
GO:0031123
IMP
Genome ProjectRNA 3'-end processing
GO:0031123
IMP
Gene OntologyRNA 3'-end processing1 2
GO:0031054
IMP
Genome Projectpre-miRNA processing
GO:0031054
IMP
Gene Ontologypre-miRNA processing1 2
GO:0019827
IMP
Genome Projectstem cell population maintenance
GO:0019827
IMP
Gene Ontologystem cell population maintenance2
GO:0017148
ISS
Genome Projectnegative regulation of translation
GO:0017148
ISS
Gene Ontologynegative regulation of translation
GO:0010587
IMP
Genome ProjectmiRNA catabolic process
GO:0010587
IMP
Gene OntologymiRNA catabolic process1 2
GO:0007281
IEA
Genome Projectgerm cell development
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:2000767
IMP
Gene Ontologypositive regulation of cytoplasmic translation3
GO:0071103
IEA
PLAZA Integrative OrthologyDNA conformation change AT4G36020
GO:0048477
IEA
PLAZA Integrative Orthologyoogenesis FBgn0035626
GO:0009737
IEA
PLAZA Integrative Orthologyresponse to abscisic acid AT4G38680
GO:0001101
IEA
PLAZA Integrative Orthologyresponse to acid chemical AT4G36020
GO:0043457
IEA
PLAZA Integrative Orthologyregulation of cellular respiration AT4G38680
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization AT4G36020
GO:1901698
IEA
PLAZA Integrative Orthologyresponse to nitrogen compound FBgn0035626
GO:0007167
IEA
PLAZA Integrative Orthologyenzyme linked receptor protein signaling pathway FBgn0035626
GO:0048589
IEA
PLAZA Integrative Orthologydevelopmental growth AT2G17870
GO:1901699
IEA
PLAZA Integrative Orthologycellular response to nitrogen compound FBgn0035626
GO:0007166
IEA
PLAZA Integrative Orthologycell surface receptor signaling pathway FBgn0035626
GO:0007169
IEA
PLAZA Integrative Orthologytransmembrane receptor protein tyrosine kinase signaling pathway FBgn0035626
GO:0015980
IEA
PLAZA Integrative Orthologyenergy derivation by oxidation of organic compounds AT4G38680
GO:0010035
IEA
PLAZA Integrative Orthologyresponse to inorganic substance AT4G36020
GO:0097305
IEA
PLAZA Integrative Orthologyresponse to alcohol AT4G38680
GO:0032508
IEA
PLAZA Integrative OrthologyDNA duplex unwinding AT4G36020
GO:0048466
IEA
PLAZA Integrative Orthologyandroecium development AT4G38680
GO:0032868
IEA
PLAZA Integrative Orthologyresponse to insulin FBgn0035626
GO:0007549
IEA
PLAZA Integrative Orthologydosage compensation WBGene00003014
GO:0032989
IEA
PLAZA Integrative Orthologycellular component morphogenesis AT2G17870
GO:0032869
IEA
PLAZA Integrative Orthologycellular response to insulin stimulus FBgn0035626
GO:1900078
IEA
PLAZA Integrative Orthologypositive regulation of cellular response to insulin stimulus FBgn0035626
GO:1900076
IEA
PLAZA Integrative Orthologyregulation of cellular response to insulin stimulus FBgn0035626
GO:0016049
IEA
PLAZA Integrative Orthologycell growth AT2G17870
GO:0032870
IEA
PLAZA Integrative Orthologycellular response to hormone stimulus FBgn0035626
GO:0010228
IEA
PLAZA Integrative Orthologyvegetative to reproductive phase transition of meristem AT4G38680
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis AT4G36020
GO:0010501
IEA
PLAZA Integrative OrthologyRNA secondary structure unwinding AT4G36020
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization AT4G36020
GO:0043434
IEA
PLAZA Integrative Orthologyresponse to peptide hormone FBgn0035626
GO:0045333
IEA
PLAZA Integrative Orthologycellular respiration AT4G38680
GO:0048608
IEA
PLAZA Integrative Orthologyreproductive structure development AT4G38680
GO:0006091
IEA
PLAZA Integrative Orthologygeneration of precursor metabolites and energy AT4G38680
GO:0010453
IEA
PLAZA Integrative Orthologyregulation of cell fate commitment WBGene00003014
GO:0017145
IEA
PLAZA Integrative Orthologystem cell division FBgn0035626
GO:0048443
IEA
PLAZA Integrative Orthologystamen development AT4G38680
GO:0009908
IEA
PLAZA Integrative Orthologyflower development AT4G38680
GO:0060969
IEA
PLAZA Integrative Orthologynegative regulation of gene silencing WBGene00003014
GO:0009628
IEA
PLAZA Integrative Orthologyresponse to abiotic stimulus AT4G36020
GO:0060967
IEA
PLAZA Integrative Orthologynegative regulation of gene silencing by RNA WBGene00003014
GO:0009631
IEA
PLAZA Integrative Orthologycold acclimation AT4G36020
GO:0048437
IEA
PLAZA Integrative Orthologyfloral organ development AT4G38680
GO:0048316
IEA
PLAZA Integrative Orthologyseed development AT4G38680
GO:0060965
IEA
PLAZA Integrative Orthologynegative regulation of gene silencing by miRNA WBGene00003014
GO:0048438
IEA
PLAZA Integrative Orthologyfloral whorl development AT4G38680
GO:0060560
IEA
PLAZA Integrative Orthologydevelopmental growth involved in morphogenesis AT2G17870
GO:0040034
IEA
PLAZA Integrative Orthologyregulation of development, heterochronic WBGene00003014
GO:0007292
IEA
PLAZA Integrative Orthologyfemale gamete generation FBgn0035626
GO:0010243
IEA
PLAZA Integrative Orthologyresponse to organonitrogen compound FBgn0035626
GO:0098725
IEA
PLAZA Integrative Orthologysymmetric cell division FBgn0035626
GO:0098724
IEA
PLAZA Integrative Orthologysymmetric stem cell division FBgn0035626
GO:0055114
IEA
PLAZA Integrative Orthologyoxidation-reduction process AT4G38680
GO:0045165
IEA
PLAZA Integrative Orthologycell fate commitment WBGene00003014
GO:0051276
IEA
PLAZA Integrative Orthologychromosome organization AT4G36020
GO:0006950
IEA
PLAZA Integrative Orthologyresponse to stress AT4G36020
GO:0048827
IEA
PLAZA Integrative Orthologyphyllome development AT4G38680
GO:1901652
IEA
PLAZA Integrative Orthologyresponse to peptide FBgn0035626
GO:0009269
IEA
PLAZA Integrative Orthologyresponse to desiccation AT4G38680
GO:1901653
IEA
PLAZA Integrative Orthologycellular response to peptide FBgn0035626
GO:1903799
IEA
PLAZA Integrative Orthologynegative regulation of production of miRNAs involved in gene silencing by miRNA WBGene00003014
GO:0031053
IEA
PLAZA Integrative Orthologyprimary miRNA processing WBGene00003014
GO:0009266
IEA
PLAZA Integrative Orthologyresponse to temperature stimulus AT4G36020
GO:0090567
IEA
PLAZA Integrative Orthologyreproductive shoot system development AT4G38680
GO:0033993
IEA
PLAZA Integrative Orthologyresponse to lipid AT4G38680
GO:0072089
IEA
PLAZA Integrative Orthologystem cell proliferation FBgn0035626
GO:0099402
IEA
PLAZA Integrative Orthologyplant organ development AT4G38680
GO:0009409
IEA
PLAZA Integrative Orthologyresponse to cold AT4G36020
GO:0051301
IEA
PLAZA Integrative Orthologycell division FBgn0035626
GO:0009414
IEA
PLAZA Integrative Orthologyresponse to water deprivation AT4G36020
GO:0060149
IEA
PLAZA Integrative Orthologynegative regulation of posttranscriptional gene silencing WBGene00003014
GO:0009415
IEA
PLAZA Integrative Orthologyresponse to water AT4G36020
GO:0009653
IEA
PLAZA Integrative Orthologyanatomical structure morphogenesis AT2G17870
GO:0072091
IEA
PLAZA Integrative Orthologyregulation of stem cell proliferation FBgn0035626
GO:0008286
IEA
PLAZA Integrative Orthologyinsulin receptor signaling pathway FBgn0035626
GO:0009651
IEA
PLAZA Integrative Orthologyresponse to salt stress AT4G36020
GO:0032392
IEA
PLAZA Integrative OrthologyDNA geometric change AT4G36020
GO:0009719
IEA
PLAZA Integrative Orthologyresponse to endogenous stimulus AT4G38680
GO:2000648
IEA
PLAZA Integrative Orthologypositive regulation of stem cell proliferation FBgn0035626
GO:0051253
IEA
PLAZA Integrative Orthologynegative regulation of RNA metabolic process WBGene00003014
GO:0040007
IEA
PLAZA Integrative Orthologygrowth AT2G17870
GO:0045934
IEA
PLAZA Integrative Orthologynegative regulation of nucleobase-containing compound metabolic process WBGene00003014
GO:0046626
IEA
PLAZA Integrative Orthologyregulation of insulin receptor signaling pathway FBgn0035626
GO:0009725
IEA
PLAZA Integrative Orthologyresponse to hormone AT4G38680
GO:0006970
IEA
PLAZA Integrative Orthologyresponse to osmotic stress AT4G36020
GO:0000902
IEA
PLAZA Integrative Orthologycell morphogenesis AT2G17870
GO:0046628
IEA
PLAZA Integrative Orthologypositive regulation of insulin receptor signaling pathway FBgn0035626
GO:0010154
IEA
PLAZA Integrative Orthologyfruit development AT4G38680
GO:0071417
IEA
PLAZA Integrative Orthologycellular response to organonitrogen compound FBgn0035626
GO:0001708
IEA
PLAZA Integrative Orthologycell fate specification WBGene00003014
GO:2000634
IEA
PLAZA Integrative Orthologyregulation of primary miRNA processing WBGene00003014
GO:2000632
IEA
PLAZA Integrative Orthologynegative regulation of pre-miRNA processing FBgn0035626
GO:2000631
IEA
PLAZA Integrative Orthologyregulation of pre-miRNA processing FBgn0035626
GO:0071375
IEA
PLAZA Integrative Orthologycellular response to peptide hormone stimulus FBgn0035626
GO:0071495
IEA
PLAZA Integrative Orthologycellular response to endogenous stimulus FBgn0035626
GO:0048367
IEA
PLAZA Integrative Orthologyshoot system development AT4G38680
GO:2000635
IEA
PLAZA Integrative Orthologynegative regulation of primary miRNA processing WBGene00003014
GO:0009826
IEA
PLAZA Integrative Orthologyunidimensional cell growth AT2G17870
GO:0061458
IEA
PLAZA Integrative Orthologyreproductive system development AT4G38680
GO:0043467
IEA
PLAZA Integrative Orthologyregulation of generation of precursor metabolites and energy AT4G38680
GO:0009791
IEA
PLAZA Integrative Orthologypost-embryonic development AT4G38680
GO:0009793
IEA
PLAZA Integrative Orthologyembryo development ending in seed dormancy AT2G21060
GO:0042659
IEA
PLAZA Integrative Orthologyregulation of cell fate specification WBGene00003014
GO:0009790
IEA
PLAZA Integrative Orthologyembryo development AT2G21060

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1990825
ISS
Genome Projectsequence-specific mRNA binding
GO:1990825
ISS
Gene Ontologysequence-specific mRNA binding
GO:0035198
ISS
Genome ProjectmiRNA binding
GO:0035198
ISS
Gene OntologymiRNA binding
GO:0031369
IEA
Genome Projecttranslation initiation factor binding
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding2 3
GO:0003723
IDA
Genome ProjectRNA binding
GO:0003723
IDA
Gene OntologyRNA binding1 2
GO:0003677
IEA
Genome ProjectDNA binding
GO:0002151
ISS
Genome ProjectG-quadruplex RNA binding
GO:0002151
ISS
Gene OntologyG-quadruplex RNA binding
GO:1905538
IDA
Gene Ontologypolysome binding3
GO:0019899
IEA
PLAZA Integrative Orthologyenzyme binding WBGene00003014
GO:0070878
IEA
PLAZA Integrative Orthologyprimary miRNA binding WBGene00003014
GO:0070883
IEA
PLAZA Integrative Orthologypre-miRNA binding WBGene00003014
GO:1990715
IEA
PLAZA Integrative OrthologymRNA CDS binding WBGene00003014
GO:0003730
IEA
PLAZA Integrative OrthologymRNA 3'-UTR binding WBGene00003014
GO:0003697
IEA
PLAZA Integrative Orthologysingle-stranded DNA binding AT4G36020
GO:0003690
IEA
PLAZA Integrative Orthologydouble-stranded DNA binding AT4G36020

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0010494
IDA
Genome Projectcytoplasmic stress granule
GO:0010494
IDA
Gene Ontologycytoplasmic stress granule4
GO:0005829
TAS
Genome Projectcytosol
GO:0005829
TAS
Gene Ontologycytosol
GO:0005791
ISS
Genome Projectrough endoplasmic reticulum
GO:0005791
ISS
Gene Ontologyrough endoplasmic reticulum
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005737
IDA
Gene Ontologycytoplasm5 6
GO:0005730
IEA
Genome Projectnucleolus
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus4
GO:0000932
IDA
Genome ProjectP-body
GO:0000932
IDA
Gene OntologyP-body4
GO:1990904
IDA
Gene Ontologyribonucleoprotein complex3
GO:0005844
IDA
Gene Ontologypolysome3
GO:0016020
IEA
PLAZA Integrative Orthologymembrane AT4G38680
GO:0071944
IEA
PLAZA Integrative Orthologycell periphery AT4G38680
GO:0005886
IEA
PLAZA Integrative Orthologyplasma membrane AT4G38680

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001878Zinc finger, CCHC-type
IPR002059Cold-shock protein, DNA-binding
IPR011129Cold shock domain
IPR012340Nucleic acid-binding, OB-fold

No MapMan annotations defined for this gene.
KeggID Description
K18754LIN28; protein lin-28
No chloroplast target sequence found.