Gene: ENSG00000131507 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000131507
Transcript Identifier
ENST00000253814
Gene Type
Coding gene
Location
5 : 142108975-142144674 : positive

Family Information

Homologous gene family
HOM02SEM027469
(3 genes in 2 species)
specific family
Orthologous gene family
ORTHO02SEM016763
(3 genes in 2 species)
specific family

Descriptions

gene_descr
Nedd4 family interacting protein 1

Identifiers

Type Value
pidENSP00000253814
HGNC17592
UniprotQ9BT67
RefSeq_mRNANM_030571.3
EMBLAB097010
EMBLAB097037
EMBLAK075495
EMBLAK075524
EMBLAK315481
EMBLAL832993
EMBLAY192728
EMBLBC004317
EMBLCH471062

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0051224
IMP
Genome Projectnegative regulation of protein transport
GO:0051224
IMP
Gene Ontologynegative regulation of protein transport1
GO:0050728
IEA
Genome Projectnegative regulation of inflammatory response
GO:0048302
IEA
Genome Projectregulation of isotype switching to IgG isotypes
GO:0048294
IEA
Genome Projectnegative regulation of isotype switching to IgE isotypes
GO:0045732
IEA
Genome Projectpositive regulation of protein catabolic process
GO:0045619
IEA
Genome Projectregulation of lymphocyte differentiation
GO:0043123
IMP
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043123
Gene Ontologypositive regulation of I-kappaB kinase/NF-kappaB signaling2
GO:0042130
IEA
Genome Projectnegative regulation of T cell proliferation
GO:0032713
IEA
Genome Projectnegative regulation of interleukin-4 production
GO:0032410
IMP
Genome Projectnegative regulation of transporter activity
GO:0032410
IMP
Gene Ontologynegative regulation of transporter activity1
GO:0031398
IDA, IMP
Genome Projectpositive regulation of protein ubiquitination
GO:0031398
IDA, IMP
Gene Ontologypositive regulation of protein ubiquitination1 3
GO:0030001
IEA
Genome Projectmetal ion transport
GO:0010629
IMP
Genome Projectnegative regulation of gene expression
GO:0010629
IMP
Gene Ontologynegative regulation of gene expression1
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007034
IEA
Genome Projectvacuolar transport
GO:0006879
IMP
Genome Projectcellular iron ion homeostasis
GO:0006879
IMP
Gene Ontologycellular iron ion homeostasis1
GO:0002829
IEA
Genome Projectnegative regulation of type 2 immune response
GO:0002761
IEA
Genome Projectregulation of myeloid leukocyte differentiation
GO:0007219
IEA
PLAZA Integrative OrthologyNotch signaling pathway FBgn0052177
GO:0009888
IEA
PLAZA Integrative Orthologytissue development FBgn0052177
GO:0060429
IEA
PLAZA Integrative Orthologyepithelium development FBgn0052177
GO:0007166
IEA
PLAZA Integrative Orthologycell surface receptor signaling pathway FBgn0052177
GO:0007444
IEA
PLAZA Integrative Orthologyimaginal disc development FBgn0052177
GO:0035295
IEA
PLAZA Integrative Orthologytube development FBgn0052177
GO:0008593
IEA
PLAZA Integrative Orthologyregulation of Notch signaling pathway FBgn0052177
GO:0035220
IEA
PLAZA Integrative Orthologywing disc development FBgn0052177

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 3 4
GO:0050699
IEA
PLAZA Integrative OrthologyWW domain binding ENSG00000102471
GO:0019904
IEA
PLAZA Integrative Orthologyprotein domain specific binding ENSG00000102471

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0048471
IDA
Genome Projectperinuclear region of cytoplasm
GO:0048471
IDA
Gene Ontologyperinuclear region of cytoplasm1
GO:0045202
IEA
Genome Projectsynapse
GO:0030425
IEA
Genome Projectdendrite
GO:0030054
IEA
Genome Projectcell junction
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0010008
IEA
Genome Projectendosome membrane
GO:0005938
IEA
Genome Projectcell cortex
GO:0005576
IEA
Genome Projectextracellular region
GO:0000139
IEA
Genome ProjectGolgi membrane
GO:0032991
IEA
PLAZA Integrative Orthologyprotein-containing complex FBgn0052177
GO:0005739
IEA
PLAZA Integrative Orthologymitochondrion ENSG00000102471
GO:0000151
IEA
PLAZA Integrative Orthologyubiquitin ligase complex FBgn0052177
GO:1990234
IEA
PLAZA Integrative Orthologytransferase complex FBgn0052177
GO:0005783
IEA
PLAZA Integrative Orthologyendoplasmic reticulum ENSG00000102471
GO:0005770
IEA
PLAZA Integrative Orthologylate endosome FBgn0052177
GO:1902494
IEA
PLAZA Integrative Orthologycatalytic complex FBgn0052177

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR019325NEDD4/Bsd2

No MapMan annotations defined for this gene.
No Kegg annotations defined for this gene.
No chloroplast target sequence found.