Gene: ENSG00000127580 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000127580
Transcript Identifier
ENST00000248142
Gene Type
Coding gene
Location
16 : 684734-690444 : negative

Family Information

Homologous gene family
HOM02SEM003948
(20 genes in 18 species)
specific family

Descriptions

gene_descr
WD repeat domain 24

Identifiers

Type Value
pidENSP00000248142
HGNC20852
UniprotQ96S15
EMBLAE006464
EMBLAL136863
EMBLBC008025
EMBLBC009761
EMBLCH471112
EMBLZ92544

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0034198
IMP
Genome Projectcellular response to amino acid starvation
GO:0034198
IMP
Gene Ontologycellular response to amino acid starvation1
GO:0032008
IMP
Genome Projectpositive regulation of TOR signaling
GO:0032008
IMP
Gene Ontologypositive regulation of TOR signaling1 2
GO:0010506
IMP
Genome Projectregulation of autophagy
GO:0010506
IMP
Gene Ontologyregulation of autophagy2
GO:0006914
IEA
Genome Projectautophagy
GO:0071704
IEA
PLAZA Integrative Orthologyorganic substance metabolic process SPAC4F8.11
GO:0031325
IEA
PLAZA Integrative Orthologypositive regulation of cellular metabolic process FBgn0027518
GO:0006873
IEA
PLAZA Integrative Orthologycellular ion homeostasis FBgn0027518
GO:0055080
IEA
PLAZA Integrative Orthologycation homeostasis FBgn0027518
GO:0043412
IEA
PLAZA Integrative Orthologymacromolecule modification SPAC4F8.11
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization FBgn0027518
GO:0044267
IEA
PLAZA Integrative Orthologycellular protein metabolic process SPAC4F8.11
GO:0007042
IEA
PLAZA Integrative Orthologylysosomal lumen acidification FBgn0027518
GO:1903432
IEA
PLAZA Integrative Orthologyregulation of TORC1 signaling YOL138C
GO:0007040
IEA
PLAZA Integrative Orthologylysosome organization FBgn0027518
GO:0019725
IEA
PLAZA Integrative Orthologycellular homeostasis FBgn0027518
GO:0055082
IEA
PLAZA Integrative Orthologycellular chemical homeostasis FBgn0027518
GO:0038202
IEA
PLAZA Integrative OrthologyTORC1 signaling YOL138C
GO:0016236
IEA
PLAZA Integrative Orthologymacroautophagy FBgn0027518
GO:0030641
IEA
PLAZA Integrative Orthologyregulation of cellular pH FBgn0027518
GO:0030003
IEA
PLAZA Integrative Orthologycellular cation homeostasis FBgn0027518
GO:0030004
IEA
PLAZA Integrative Orthologycellular monovalent inorganic cation homeostasis FBgn0027518
GO:0031331
IEA
PLAZA Integrative Orthologypositive regulation of cellular catabolic process FBgn0027518
GO:0044260
IEA
PLAZA Integrative Orthologycellular macromolecule metabolic process SPAC4F8.11
GO:0043170
IEA
PLAZA Integrative Orthologymacromolecule metabolic process SPAC4F8.11
GO:0007035
IEA
PLAZA Integrative Orthologyvacuolar acidification FBgn0027518
GO:0009896
IEA
PLAZA Integrative Orthologypositive regulation of catabolic process FBgn0027518
GO:1901564
IEA
PLAZA Integrative Orthologyorganonitrogen compound metabolic process SPAC4F8.11
GO:0006464
IEA
PLAZA Integrative Orthologycellular protein modification process SPAC4F8.11
GO:0007033
IEA
PLAZA Integrative Orthologyvacuole organization FBgn0027518
GO:0009893
IEA
PLAZA Integrative Orthologypositive regulation of metabolic process FBgn0027518
GO:0019538
IEA
PLAZA Integrative Orthologyprotein metabolic process SPAC4F8.11
GO:0016049
IEA
PLAZA Integrative Orthologycell growth FBgn0027518
GO:0050801
IEA
PLAZA Integrative Orthologyion homeostasis FBgn0027518
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis FBgn0027518
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization FBgn0027518
GO:0016241
IEA
PLAZA Integrative Orthologyregulation of macroautophagy FBgn0027518
GO:0042592
IEA
PLAZA Integrative Orthologyhomeostatic process FBgn0027518
GO:0051452
IEA
PLAZA Integrative Orthologyintracellular pH reduction FBgn0027518
GO:0001558
IEA
PLAZA Integrative Orthologyregulation of cell growth FBgn0027518
GO:0006807
IEA
PLAZA Integrative Orthologynitrogen compound metabolic process SPAC4F8.11
GO:0051453
IEA
PLAZA Integrative Orthologyregulation of intracellular pH FBgn0027518
GO:0010508
IEA
PLAZA Integrative Orthologypositive regulation of autophagy FBgn0027518
GO:0040007
IEA
PLAZA Integrative Orthologygrowth FBgn0027518
GO:0040008
IEA
PLAZA Integrative Orthologyregulation of growth FBgn0027518
GO:0045851
IEA
PLAZA Integrative OrthologypH reduction FBgn0027518
GO:0055067
IEA
PLAZA Integrative Orthologymonovalent inorganic cation homeostasis FBgn0027518
GO:0035751
IEA
PLAZA Integrative Orthologyregulation of lysosomal lumen pH FBgn0027518
GO:1904263
IEA
PLAZA Integrative Orthologypositive regulation of TORC1 signaling YOL138C
GO:0065008
IEA
PLAZA Integrative Orthologyregulation of biological quality FBgn0027518
GO:0016239
IEA
PLAZA Integrative Orthologypositive regulation of macroautophagy FBgn0027518
GO:0051128
IEA
PLAZA Integrative Orthologyregulation of cellular component organization FBgn0027518
GO:0070647
IEA
PLAZA Integrative Orthologyprotein modification by small protein conjugation or removal SPAC4F8.11
GO:0098771
IEA
PLAZA Integrative Orthologyinorganic ion homeostasis FBgn0027518
GO:0030307
IEA
PLAZA Integrative Orthologypositive regulation of cell growth FBgn0027518
GO:0006885
IEA
PLAZA Integrative Orthologyregulation of pH FBgn0027518
GO:0044238
IEA
PLAZA Integrative Orthologyprimary metabolic process SPAC4F8.11
GO:0048878
IEA
PLAZA Integrative Orthologychemical homeostasis FBgn0027518
GO:0080171
IEA
PLAZA Integrative Orthologylytic vacuole organization FBgn0027518
GO:0045927
IEA
PLAZA Integrative Orthologypositive regulation of growth FBgn0027518
GO:0036211
IEA
PLAZA Integrative Orthologyprotein modification process SPAC4F8.11

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding3 4 5 6 7 8 9

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0061700
IDA
Genome ProjectGATOR2 complex
GO:0061700
IDA
Gene OntologyGATOR2 complex1
GO:0005765
IDA
Genome Projectlysosomal membrane
GO:0005765
IDA
Gene Ontologylysosomal membrane10
GO:0019898
IEA
PLAZA Integrative Orthologyextrinsic component of membrane YOL138C
GO:0097042
IEA
PLAZA Integrative Orthologyextrinsic component of fungal-type vacuolar membrane YOL138C
GO:0000322
IEA
PLAZA Integrative Orthologystorage vacuole YOL138C
GO:0044425
IEA
PLAZA Integrative Orthologymembrane part YOL138C
GO:0000324
IEA
PLAZA Integrative Orthologyfungal-type vacuole YOL138C
GO:0000329
IEA
PLAZA Integrative Orthologyfungal-type vacuole membrane YOL138C
GO:1990904
IEA
PLAZA Integrative Orthologyribonucleoprotein complex YOL138C
GO:0005767
IEA
PLAZA Integrative Orthologysecondary lysosome FBgn0027518
GO:0005776
IEA
PLAZA Integrative Orthologyautophagosome FBgn0027518
GO:0005840
IEA
PLAZA Integrative Orthologyribosome YOL138C
GO:0043232
IEA
PLAZA Integrative Orthologyintracellular non-membrane-bounded organelle YOL138C
GO:0000306
IEA
PLAZA Integrative Orthologyextrinsic component of vacuolar membrane YOL138C
GO:0031312
IEA
PLAZA Integrative Orthologyextrinsic component of organelle membrane YOL138C
GO:0005829
IEA
PLAZA Integrative Orthologycytosol SPAC4F8.11
GO:0043228
IEA
PLAZA Integrative Orthologynon-membrane-bounded organelle YOL138C
GO:0044754
IEA
PLAZA Integrative Orthologyautolysosome FBgn0027518

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001680WD40 repeat
IPR015943WD40/YVTN repeat-like-containing domain superfamily
IPR017986WD40-repeat-containing domain
IPR019775WD40 repeat, conserved site

No MapMan annotations defined for this gene.
No Kegg annotations defined for this gene.
No chloroplast target sequence found.