Gene: ENSG00000116586 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000116586
Transcript Identifier
ENST00000368302
Gene Type
Coding gene
Location
1 : 156054890-156058409 : positive

Family Information

Homologous gene family
HOM02SEM020078
(4 genes in 4 species)
specific family

Descriptions

gene_descr
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2

Identifiers

Type Value
pidENSP00000357285
HGNC29796
UniprotQ9Y2Q5

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0071230
IMP
Genome Projectcellular response to amino acid stimulus
GO:0071230
IMP
Gene Ontologycellular response to amino acid stimulus1
GO:0043547
IEA
Genome Projectpositive regulation of GTPase activity
GO:0043312
TAS
Genome Projectneutrophil degranulation
GO:0043312
TAS
Gene Ontologyneutrophil degranulation
GO:0034613
IMP
Genome Projectcellular protein localization
GO:0034613
IMP
Gene Ontologycellular protein localization1
GO:0032008
IMP
Genome Projectpositive regulation of TOR signaling
GO:0032008
IMP
Gene Ontologypositive regulation of TOR signaling1
GO:0016241
TAS
Genome Projectregulation of macroautophagy
GO:0016241
TAS
Gene Ontologyregulation of macroautophagy
GO:0016049
IMP
Genome Projectcell growth
GO:0007050
TAS
Genome Projectcell cycle arrest
GO:0007050
TAS
Gene Ontologycell cycle arrest
GO:0000186
IEA
Genome Projectactivation of MAPKK activity
GO:0000165
TAS
Genome ProjectMAPK cascade
GO:0000165
TAS
Gene OntologyMAPK cascade
GO:0001558
IMP
Gene Ontologyregulation of cell growth1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0032947
IDA
Genome Projectprotein-containing complex scaffold activity
GO:0032947
IDA
Gene Ontologyprotein-containing complex scaffold activity2
GO:0005085
IDA
Genome Projectguanyl-nucleotide exchange factor activity
GO:0005085
IDA
Gene Ontologyguanyl-nucleotide exchange factor activity2
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 2 3 4 5 6 7

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0071986
IDA
Genome ProjectRagulator complex
GO:0071986
IDA
Gene OntologyRagulator complex1
GO:0070821
TAS
Genome Projecttertiary granule membrane
GO:0070821
TAS
Gene Ontologytertiary granule membrane
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0035579
TAS
Genome Projectspecific granule membrane
GO:0035579
TAS
Gene Ontologyspecific granule membrane
GO:0010008
TAS
Genome Projectendosome membrane
GO:0010008
TAS
Gene Ontologyendosome membrane
GO:0005886
TAS
Genome Projectplasma membrane
GO:0005886
TAS
Gene Ontologyplasma membrane
GO:0005770
ISS
Genome Projectlate endosome
GO:0005770
ISS
Gene Ontologylate endosome
GO:0005765
IDA
TAS
Genome Projectlysosomal membrane
GO:0005765
TAS
Gene Ontologylysosomal membrane8

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR004942Roadblock/LAMTOR2 domain

No MapMan annotations defined for this gene.
No Kegg annotations defined for this gene.
No chloroplast target sequence found.