Gene: ENSG00000116539 (Homo sapiens)

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Gene Identifier
ENSG00000116539
Transcript Identifier
ENST00000368346
Gene Type
Coding gene
Location
1 : 155337660-155521519 : negative

Family Information

Homologous gene family
HOM02SEM000111
(211 genes in 26 species)
specific family

Descriptions

gene_descr
ash1 (absent, small, or homeotic)-like (Drosophila)

Identifiers

Type Value
pidENSP00000357330
HGNC19088
UniprotQ9NR48

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1903709
IEA
Genome Projectuterine gland development
GO:1903699
IEA
Genome Projecttarsal gland development
GO:0097722
IEA
Genome Projectsperm motility
GO:0097676
IDA
Genome Projecthistone H3-K36 dimethylation
GO:0097676
IDA
Gene Ontologyhistone H3-K36 dimethylation1
GO:0061038
IEA
Genome Projectuterus morphogenesis
GO:0051568
IEA
Genome Projecthistone H3-K4 methylation
GO:0046697
IEA
Genome Projectdecidualization
GO:0045944
IEA
Genome Projectpositive regulation of transcription by RNA polymerase II
GO:0043409
IEA
Genome Projectnegative regulation of MAPK cascade
GO:0043124
IEA
Genome Projectnegative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032635
IEA
Genome Projectinterleukin-6 production
GO:0009791
IEA
Genome Projectpost-embryonic development
GO:0007338
IEA
Genome Projectsingle fertilization
GO:0007267
TAS
Genome Projectcell-cell signaling
GO:0007267
TAS
Gene Ontologycell-cell signaling2
GO:0006366
TAS
Genome Projecttranscription by RNA polymerase II
GO:0006366
TAS
Gene Ontologytranscription by RNA polymerase II2
GO:0006323
TAS
Genome ProjectDNA packaging
GO:0006323
TAS
Gene OntologyDNA packaging2
GO:0002674
IEA
Genome Projectnegative regulation of acute inflammatory response
GO:0001501
IEA
Genome Projectskeletal system development
GO:0009790
IEA
PLAZA Integrative Orthologyembryo development WBGene00003040
GO:0009792
IEA
PLAZA Integrative Orthologyembryo development ending in birth or egg hatching WBGene00003040
GO:1905268
IEA
PLAZA Integrative Orthologynegative regulation of chromatin organization FBgn0005386
GO:1902275
IEA
PLAZA Integrative Orthologyregulation of chromatin organization FBgn0005386
GO:0007530
IEA
PLAZA Integrative Orthologysex determination WBGene00003222
GO:0048638
IEA
PLAZA Integrative Orthologyregulation of developmental growth WBGene00003040
GO:0005996
IEA
PLAZA Integrative Orthologymonosaccharide metabolic process FBgn0005386
GO:0044281
IEA
PLAZA Integrative Orthologysmall molecule metabolic process FBgn0005386
GO:0050793
IEA
PLAZA Integrative Orthologyregulation of developmental process WBGene00003040
GO:0001700
IEA
PLAZA Integrative Orthologyembryonic development via the syncytial blastoderm FBgn0005386
GO:0002119
IEA
PLAZA Integrative Orthologynematode larval development WBGene00003040
GO:0001704
IEA
PLAZA Integrative Orthologyformation of primary germ layer WBGene00003040
GO:0001705
IEA
PLAZA Integrative Orthologyectoderm formation WBGene00003040
GO:0001708
IEA
PLAZA Integrative Orthologycell fate specification WBGene00003040
GO:0051129
IEA
PLAZA Integrative Orthologynegative regulation of cellular component organization FBgn0005386
GO:0051128
IEA
PLAZA Integrative Orthologyregulation of cellular component organization FBgn0005386
GO:0045815
IEA
PLAZA Integrative Orthologypositive regulation of gene expression, epigenetic FBgn0005386
GO:0062012
IEA
PLAZA Integrative Orthologyregulation of small molecule metabolic process FBgn0005386
GO:0045138
IEA
PLAZA Integrative Orthologynematode male tail tip morphogenesis WBGene00003040
GO:0048646
IEA
PLAZA Integrative Orthologyanatomical structure formation involved in morphogenesis WBGene00003040
GO:0040008
IEA
PLAZA Integrative Orthologyregulation of growth WBGene00003040
GO:0040007
IEA
PLAZA Integrative Orthologygrowth WBGene00003040
GO:0001712
IEA
PLAZA Integrative Orthologyectodermal cell fate commitment WBGene00003040
GO:0001715
IEA
PLAZA Integrative Orthologyectodermal cell fate specification WBGene00003040
GO:0010668
IEA
PLAZA Integrative Orthologyectodermal cell differentiation WBGene00003040
GO:0048096
IEA
PLAZA Integrative Orthologychromatin-mediated maintenance of transcription FBgn0005386
GO:0035264
IEA
PLAZA Integrative Orthologymulticellular organism growth WBGene00003040
GO:0031060
IEA
PLAZA Integrative Orthologyregulation of histone methylation FBgn0005386
GO:0031061
IEA
PLAZA Integrative Orthologynegative regulation of histone methylation FBgn0005386
GO:0040014
IEA
PLAZA Integrative Orthologyregulation of multicellular organism growth WBGene00003040
GO:0010639
IEA
PLAZA Integrative Orthologynegative regulation of organelle organization FBgn0005386
GO:0031057
IEA
PLAZA Integrative Orthologynegative regulation of histone modification FBgn0005386
GO:0031056
IEA
PLAZA Integrative Orthologyregulation of histone modification FBgn0005386
GO:0016458
IEA
PLAZA Integrative Orthologygene silencing WBGene00003222
GO:0040029
IEA
PLAZA Integrative Orthologyregulation of gene expression, epigenetic WBGene00003222
GO:0007369
IEA
PLAZA Integrative Orthologygastrulation WBGene00003040
GO:0005975
IEA
PLAZA Integrative Orthologycarbohydrate metabolic process FBgn0005386
GO:0045165
IEA
PLAZA Integrative Orthologycell fate commitment WBGene00003040
GO:0070734
IEA
PLAZA Integrative Orthologyhistone H3-K27 methylation FBgn0005386
GO:0007292
IEA
PLAZA Integrative Orthologyfemale gamete generation FBgn0005386
GO:2001251
IEA
PLAZA Integrative Orthologynegative regulation of chromosome organization FBgn0005386
GO:0019318
IEA
PLAZA Integrative Orthologyhexose metabolic process FBgn0005386
GO:0002164
IEA
PLAZA Integrative Orthologylarval development WBGene00003040
GO:0006006
IEA
PLAZA Integrative Orthologyglucose metabolic process FBgn0005386
GO:0007610
IEA
PLAZA Integrative Orthologybehavior WBGene00003040
GO:0048566
IEA
PLAZA Integrative Orthologyembryonic digestive tract development WBGene00003040
GO:0048565
IEA
PLAZA Integrative Orthologydigestive tract development WBGene00003040
GO:0046661
IEA
PLAZA Integrative Orthologymale sex differentiation WBGene00003040
GO:0055123
IEA
PLAZA Integrative Orthologydigestive system development WBGene00003040
GO:0018992
IEA
PLAZA Integrative Orthologygerm-line sex determination WBGene00003222
GO:0018991
IEA
PLAZA Integrative Orthologyoviposition WBGene00003040
GO:0060795
IEA
PLAZA Integrative Orthologycell fate commitment involved in formation of primary germ layer WBGene00003040
GO:0061085
IEA
PLAZA Integrative Orthologyregulation of histone H3-K27 methylation FBgn0005386
GO:0061086
IEA
PLAZA Integrative Orthologynegative regulation of histone H3-K27 methylation FBgn0005386
GO:0048568
IEA
PLAZA Integrative Orthologyembryonic organ development WBGene00003040
GO:0010629
IEA
PLAZA Integrative Orthologynegative regulation of gene expression WBGene00003222
GO:0010906
IEA
PLAZA Integrative Orthologyregulation of glucose metabolic process FBgn0005386
GO:0090598
IEA
PLAZA Integrative Orthologymale anatomical structure morphogenesis WBGene00003040
GO:0033044
IEA
PLAZA Integrative Orthologyregulation of chromosome organization FBgn0005386
GO:0033043
IEA
PLAZA Integrative Orthologyregulation of organelle organization FBgn0005386
GO:0007276
IEA
PLAZA Integrative Orthologygamete generation FBgn0005386
GO:0007398
IEA
PLAZA Integrative Orthologyectoderm development WBGene00003040
GO:0007548
IEA
PLAZA Integrative Orthologysex differentiation WBGene00003040
GO:0044262
IEA
PLAZA Integrative Orthologycellular carbohydrate metabolic process FBgn0005386
GO:0034401
IEA
PLAZA Integrative Orthologychromatin organization involved in regulation of transcription FBgn0005386
GO:0010675
IEA
PLAZA Integrative Orthologyregulation of cellular carbohydrate metabolic process FBgn0005386
GO:0007281
IEA
PLAZA Integrative Orthologygerm cell development FBgn0005386
GO:0035295
IEA
PLAZA Integrative Orthologytube development WBGene00003040
GO:0048589
IEA
PLAZA Integrative Orthologydevelopmental growth WBGene00003040
GO:0048468
IEA
PLAZA Integrative Orthologycell development FBgn0005386
GO:0048869
IEA
PLAZA Integrative Orthologycellular developmental process WBGene00003040
GO:0022412
IEA
PLAZA Integrative Orthologycellular process involved in reproduction in multicellular organism FBgn0005386
GO:0006109
IEA
PLAZA Integrative Orthologyregulation of carbohydrate metabolic process FBgn0005386
GO:0019098
IEA
PLAZA Integrative Orthologyreproductive behavior WBGene00003040
GO:0048598
IEA
PLAZA Integrative Orthologyembryonic morphogenesis WBGene00003040
GO:0048477
IEA
PLAZA Integrative Orthologyoogenesis FBgn0005386
GO:0030154
IEA
PLAZA Integrative Orthologycell differentiation WBGene00003040
GO:0051239
IEA
PLAZA Integrative Orthologyregulation of multicellular organismal process WBGene00003040

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0046975
IDA
Genome Projecthistone methyltransferase activity (H3-K36 specific)
GO:0046975
IDA
Gene Ontologyhistone methyltransferase activity (H3-K36 specific)1
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0042800
IEA
Genome Projecthistone methyltransferase activity (H3-K4 specific)
GO:0018024
TAS
Genome Projecthistone-lysine N-methyltransferase activity
GO:0018024
TAS
Gene Ontologyhistone-lysine N-methyltransferase activity
GO:0003682
IEA
Genome Projectchromatin binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0000981
ISM
NAS
Gene OntologyDNA-binding transcription factor activity, RNA polymerase II-specific3
GO:0046974
IEA
PLAZA Integrative Orthologyhistone methyltransferase activity (H3-K9 specific) FBgn0005386
GO:0035035
IEA
PLAZA Integrative Orthologyhistone acetyltransferase binding FBgn0005386
GO:0005515
IEA
PLAZA Integrative Orthologyprotein binding FBgn0005386
GO:0042799
IEA
PLAZA Integrative Orthologyhistone methyltransferase activity (H4-K20 specific) FBgn0005386
GO:0019899
IEA
PLAZA Integrative Orthologyenzyme binding FBgn0005386

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0005923
IEA
Genome Projectbicellular tight junction
GO:0005794
IDA
Genome ProjectGolgi apparatus
GO:0005794
IDA
Gene OntologyGolgi apparatus
GO:0005694
IEA
Genome Projectchromosome
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005654
IDA
TAS
Gene Ontologynucleoplasm
GO:0005634
TAS
Genome Projectnucleus
GO:0005634
TAS
Gene Ontologynucleus2
GO:0000228
IEA
PLAZA Integrative Orthologynuclear chromosome WBGene00003222
GO:0044451
IEA
PLAZA Integrative Orthologynucleoplasm part FBgn0005386
GO:0035097
IEA
PLAZA Integrative Orthologyhistone methyltransferase complex FBgn0005386
GO:0005700
IEA
PLAZA Integrative Orthologypolytene chromosome FBgn0005386
GO:0009506
IEA
PLAZA Integrative Orthologyplasmodesma AT2G44150
GO:0034708
IEA
PLAZA Integrative Orthologymethyltransferase complex FBgn0005386
GO:0000785
IEA
PLAZA Integrative Orthologychromatin AT4G30860
GO:0032991
IEA
PLAZA Integrative Orthologyprotein-containing complex FBgn0005386
GO:1902494
IEA
PLAZA Integrative Orthologycatalytic complex FBgn0005386
GO:0030849
IEA
PLAZA Integrative Orthologyautosome WBGene00003222
GO:0000805
IEA
PLAZA Integrative OrthologyX chromosome WBGene00003222
GO:0055044
IEA
PLAZA Integrative Orthologysymplast AT2G44150
GO:0000803
IEA
PLAZA Integrative Orthologysex chromosome WBGene00003222
GO:0005783
IEA
PLAZA Integrative Orthologyendoplasmic reticulum AT2G44150
GO:0044427
IEA
PLAZA Integrative Orthologychromosomal part AT4G30860
GO:1990234
IEA
PLAZA Integrative Orthologytransferase complex FBgn0005386

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001025Bromo adjacent homology (BAH) domain
IPR001214SET domain
IPR001487Bromodomain
IPR001965Zinc finger, PHD-type
IPR003616Post-SET domain
IPR006560AWS domain
IPR011011Zinc finger, FYVE/PHD-type
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR017956AT hook, DNA-binding motif
IPR019786Zinc finger, PHD-type, conserved site

No MapMan annotations defined for this gene.
KeggID Description
K06101ASH1L; histone-lysine N-methyltransferase ASH1L
No chloroplast target sequence found.