Gene: ENSG00000116237 (Homo sapiens)

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Gene Identifier
ENSG00000116237
Transcript Identifier
ENST00000343813
Gene Type
Coding gene
Location
1 : 6225080-6235911 : negative

Family Information

Homologous gene family
HOM02SEM002401
(29 genes in 21 species)
specific family
Orthologous gene family
ORTHO02SEM002773
(27 genes in 21 species)
specific family

Descriptions

gene_descr
isoprenylcysteine carboxyl methyltransferase

Identifiers

Type Value
pidENSP00000343552
HGNC5350
UniprotO60725
UniprotA0A024R4F6
RefSeq_mRNANM_012405.3
EMBLCHEMBL4699
EMBLAF064084
EMBLAL031847
EMBLBC028168
EMBLCH471130
EMBLCR541671
EMBLCR541711

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0043687
TAS
Genome Projectpost-translational protein modification
GO:0043687
TAS
Gene Ontologypost-translational protein modification
GO:0006612
TAS
Genome Projectprotein targeting to membrane
GO:0006612
TAS
Gene Ontologyprotein targeting to membrane1
GO:0006481
IEA
Genome ProjectC-terminal protein methylation
GO:0006464
TAS
Genome Projectcellular protein modification process
GO:0006464
TAS
Gene Ontologycellular protein modification process1
GO:0043900
IEA
PLAZA Integrative Orthologyregulation of multi-organism process SPAC10F6.12c
GO:0018229
IEA
PLAZA Integrative Orthologypeptidyl-L-cysteine methyl ester biosynthetic process from peptidyl-cysteine SPAC10F6.12c
GO:0043902
IEA
PLAZA Integrative Orthologypositive regulation of multi-organism process SPAC10F6.12c
GO:2000241
IEA
PLAZA Integrative Orthologyregulation of reproductive process SPAC10F6.12c
GO:0009791
IEA
PLAZA Integrative Orthologypost-embryonic development AT5G08335
GO:0048518
IEA
PLAZA Integrative Orthologypositive regulation of biological process SPAC10F6.12c
GO:0061458
IEA
PLAZA Integrative Orthologyreproductive system development AT5G08335
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction AT5G08335
GO:0050794
IEA
PLAZA Integrative Orthologyregulation of cellular process SPAC10F6.12c
GO:0018193
IEA
PLAZA Integrative Orthologypeptidyl-amino acid modification SPAC10F6.12c
GO:0048522
IEA
PLAZA Integrative Orthologypositive regulation of cellular process SPAC10F6.12c
GO:0018350
IEA
PLAZA Integrative Orthologyprotein esterification SPAC10F6.12c
GO:0048367
IEA
PLAZA Integrative Orthologyshoot system development AT5G08335
GO:0009908
IEA
PLAZA Integrative Orthologyflower development AT5G08335
GO:0018198
IEA
PLAZA Integrative Orthologypeptidyl-cysteine modification SPAC10F6.12c
GO:0018351
IEA
PLAZA Integrative Orthologypeptidyl-cysteine esterification SPAC10F6.12c
GO:0051604
IEA
PLAZA Integrative Orthologyprotein maturation SPAC10F6.12c
GO:0070887
IEA
PLAZA Integrative Orthologycellular response to chemical stimulus SPAC10F6.12c
GO:0065007
IEA
PLAZA Integrative Orthologybiological regulation SPAC10F6.12c
GO:0010033
IEA
PLAZA Integrative Orthologyresponse to organic substance SPAC10F6.12c
GO:0048608
IEA
PLAZA Integrative Orthologyreproductive structure development AT5G08335
GO:0000749
IEA
PLAZA Integrative Orthologyresponse to pheromone triggering conjugation with cellular fusion SPAC10F6.12c
GO:0000747
IEA
PLAZA Integrative Orthologyconjugation with cellular fusion SPAC10F6.12c
GO:0000746
IEA
PLAZA Integrative Orthologyconjugation SPAC10F6.12c
GO:0042221
IEA
PLAZA Integrative Orthologyresponse to chemical SPAC10F6.12c
GO:0044764
IEA
PLAZA Integrative Orthologymulti-organism cellular process SPAC10F6.12c
GO:0048731
IEA
PLAZA Integrative Orthologysystem development AT5G08335
GO:0010467
IEA
PLAZA Integrative Orthologygene expression SPAC10F6.12c
GO:0019236
IEA
PLAZA Integrative Orthologyresponse to pheromone SPAC10F6.12c
GO:2000243
IEA
PLAZA Integrative Orthologypositive regulation of reproductive process SPAC10F6.12c
GO:0071444
IEA
PLAZA Integrative Orthologycellular response to pheromone SPAC10F6.12c
GO:0019953
IEA
PLAZA Integrative Orthologysexual reproduction SPAC10F6.12c
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development AT5G08335
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development AT5G08335
GO:0046999
IEA
PLAZA Integrative Orthologyregulation of conjugation SPAC10F6.12c
GO:0071310
IEA
PLAZA Integrative Orthologycellular response to organic substance SPAC10F6.12c
GO:0071432
IEA
PLAZA Integrative Orthologypeptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion SPAC10F6.12c
GO:0051704
IEA
PLAZA Integrative Orthologymulti-organism process SPAC10F6.12c
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process AT5G08335
GO:0140253
IEA
PLAZA Integrative Orthologycell-cell fusion SPAC10F6.12c
GO:0031139
IEA
PLAZA Integrative Orthologypositive regulation of conjugation with cellular fusion SPAC10F6.12c
GO:0031136
IEA
PLAZA Integrative Orthologypositive regulation of conjugation SPAC10F6.12c
GO:0050896
IEA
PLAZA Integrative Orthologyresponse to stimulus SPAC10F6.12c
GO:0031137
IEA
PLAZA Integrative Orthologyregulation of conjugation with cellular fusion SPAC10F6.12c
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process AT5G08335
GO:0044703
IEA
PLAZA Integrative Orthologymulti-organism reproductive process SPAC10F6.12c
GO:0090567
IEA
PLAZA Integrative Orthologyreproductive shoot system development AT5G08335
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process SPAC10F6.12c
GO:0007323
IEA
PLAZA Integrative Orthologypeptide pheromone maturation SPAC10F6.12c
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction SPAC10F6.12c
GO:0051716
IEA
PLAZA Integrative Orthologycellular response to stimulus SPAC10F6.12c
GO:0018125
IEA
PLAZA Integrative Orthologypeptidyl-cysteine methylation SPAC10F6.12c
GO:0050789
IEA
PLAZA Integrative Orthologyregulation of biological process SPAC10F6.12c

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004671
TAS
Genome Projectprotein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
GO:0004671
TAS
Gene Ontologyprotein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
GO:0003880
TAS
Genome Projectprotein C-terminal carboxyl O-methyltransferase activity
GO:0003880
TAS
Gene Ontologyprotein C-terminal carboxyl O-methyltransferase activity1

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0016020
TAS
Genome Projectmembrane
GO:0016020
TAS
Gene Ontologymembrane2
GO:0005789
TAS
Genome Projectendoplasmic reticulum membrane
GO:0005789
TAS
Gene Ontologyendoplasmic reticulum membrane
GO:0005783
IDA
Genome Projectendoplasmic reticulum
GO:0005783
IDA
Gene Ontologyendoplasmic reticulum1
GO:0005635
IEA
PLAZA Integrative Orthologynuclear envelope YDR410C
GO:0005634
IEA
PLAZA Integrative Orthologynucleus YDR410C
GO:0005637
IEA
PLAZA Integrative Orthologynuclear inner membrane YDR410C
GO:0031975
IEA
PLAZA Integrative Orthologyenvelope YDR410C
GO:0019866
IEA
PLAZA Integrative Orthologyorganelle inner membrane YDR410C
GO:0044428
IEA
PLAZA Integrative Orthologynuclear part YDR410C
GO:0031090
IEA
PLAZA Integrative Orthologyorganelle membrane YDR410C
GO:0031967
IEA
PLAZA Integrative Orthologyorganelle envelope YDR410C
GO:0031965
IEA
PLAZA Integrative Orthologynuclear membrane YDR410C

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR007269Isoprenylcysteine carboxyl methyltransferase
IPR025770Protein-S-isoprenylcysteine O-methyltransferase

No MapMan annotations defined for this gene.
KeggID Description
K00587ICMT, STE14; protein-S-isoprenylcysteine O-methyltransferase [EC:2.1.1.100]
No chloroplast target sequence found.