Gene: ENSG00000110367 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000110367
Transcript Identifier
ENST00000526070
Gene Type
Coding gene
Location
11 : 118754712-118786251 : negative

Family Information

Homologous gene family
HOM02SEM000004
(1168 genes in 26 species)
specific family
Orthologous gene family
ORTHO02SEM001759
(35 genes in 25 species)
specific family

Descriptions

gene_descr
DEAD (Asp-Glu-Ala-Asp) box helicase 6

Identifiers

Type Value
pidENSP00000433704
HGNC2747
UniprotP26196
EMBLBC065007
EMBLD17532
EMBLZ11685

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0045665
IEA
Genome Projectnegative regulation of neuron differentiation
GO:0043928
TAS
Genome Projectexonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0043928
TAS
Gene Ontologyexonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0033962
IDA
Genome Projectcytoplasmic mRNA processing body assembly
GO:0033962
IDA
Gene Ontologycytoplasmic mRNA processing body assembly1
GO:0019827
IEA
Genome Projectstem cell population maintenance
GO:0019074
IMP
Genome Projectviral RNA genome packaging
GO:0019074
IMP
Gene Ontologyviral RNA genome packaging2
GO:0010501
IBA
Genome ProjectRNA secondary structure unwinding
GO:0007283
IEA
Genome Projectspermatogenesis
GO:0006417
IBA
Genome Projectregulation of translation
GO:0010564
IEA
PLAZA Integrative Orthologyregulation of cell cycle process FBgn0004419
GO:0012501
IEA
PLAZA Integrative Orthologyprogrammed cell death WBGene00000479
GO:0031644
IEA
PLAZA Integrative Orthologyregulation of neurological system process FBgn0004419
GO:0043066
IEA
PLAZA Integrative Orthologynegative regulation of apoptotic process WBGene00000479
GO:0048477
IEA
PLAZA Integrative Orthologyoogenesis FBgn0004419
GO:0010603
IEA
PLAZA Integrative Orthologyregulation of cytoplasmic mRNA processing body assembly YDL160C
GO:0006109
IEA
PLAZA Integrative Orthologyregulation of carbohydrate metabolic process FBgn0004419
GO:0022412
IEA
PLAZA Integrative Orthologycellular process involved in reproduction in multicellular organism FBgn0004419
GO:0007049
IEA
PLAZA Integrative Orthologycell cycle FBgn0004419
GO:0007568
IEA
PLAZA Integrative Orthologyaging WBGene00000479
GO:0007281
IEA
PLAZA Integrative Orthologygerm cell development FBgn0004419
GO:0034249
IEA
PLAZA Integrative Orthologynegative regulation of cellular amide metabolic process YDL160C
GO:0010675
IEA
PLAZA Integrative Orthologyregulation of cellular carbohydrate metabolic process FBgn0004419
GO:0050896
IEA
PLAZA Integrative Orthologyresponse to stimulus FBgn0004419
GO:0032101
IEA
PLAZA Integrative Orthologyregulation of response to external stimulus FBgn0004419
GO:0010558
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule biosynthetic process YDL160C
GO:0033554
IEA
PLAZA Integrative Orthologycellular response to stress FBgn0004419
GO:0044262
IEA
PLAZA Integrative Orthologycellular carbohydrate metabolic process FBgn0004419
GO:0050890
IEA
PLAZA Integrative Orthologycognition FBgn0004419
GO:0009605
IEA
PLAZA Integrative Orthologyresponse to external stimulus FBgn0004419
GO:0000086
IEA
PLAZA Integrative OrthologyG2/M transition of mitotic cell cycle FBgn0004419
GO:0009607
IEA
PLAZA Integrative Orthologyresponse to biotic stimulus FBgn0004419
GO:0048583
IEA
PLAZA Integrative Orthologyregulation of response to stimulus FBgn0004419
GO:0009615
IEA
PLAZA Integrative Orthologyresponse to virus FBgn0004419
GO:0045900
IEA
PLAZA Integrative Orthologynegative regulation of translational elongation YDL160C
GO:0007277
IEA
PLAZA Integrative Orthologypole cell development FBgn0004419
GO:0044774
IEA
PLAZA Integrative Orthologymitotic DNA integrity checkpoint FBgn0004419
GO:0007279
IEA
PLAZA Integrative Orthologypole cell formation FBgn0004419
GO:0044772
IEA
PLAZA Integrative Orthologymitotic cell cycle phase transition FBgn0004419
GO:0044773
IEA
PLAZA Integrative Orthologymitotic DNA damage checkpoint FBgn0004419
GO:0033043
IEA
PLAZA Integrative Orthologyregulation of organelle organization YDL160C
GO:0044818
IEA
PLAZA Integrative Orthologymitotic G2/M transition checkpoint FBgn0004419
GO:0046959
IEA
PLAZA Integrative Orthologyhabituation FBgn0004419
GO:0046958
IEA
PLAZA Integrative Orthologynonassociative learning FBgn0004419
GO:0043207
IEA
PLAZA Integrative Orthologyresponse to external biotic stimulus FBgn0004419
GO:0016441
IEA
PLAZA Integrative Orthologyposttranscriptional gene silencing FBgn0004419
GO:0044770
IEA
PLAZA Integrative Orthologycell cycle phase transition FBgn0004419
GO:0010906
IEA
PLAZA Integrative Orthologyregulation of glucose metabolic process FBgn0004419
GO:0098542
IEA
PLAZA Integrative Orthologydefense response to other organism FBgn0004419
GO:0030855
IEA
PLAZA Integrative Orthologyepithelial cell differentiation FBgn0004419
GO:0009888
IEA
PLAZA Integrative Orthologytissue development FBgn0004419
GO:0007346
IEA
PLAZA Integrative Orthologyregulation of mitotic cell cycle FBgn0004419
GO:0007349
IEA
PLAZA Integrative Orthologycellularization FBgn0004419
GO:0006414
IEA
PLAZA Integrative Orthologytranslational elongation YDL160C
GO:0042981
IEA
PLAZA Integrative Orthologyregulation of apoptotic process WBGene00000479
GO:0042221
IEA
PLAZA Integrative Orthologyresponse to chemical FBgn0004419
GO:0044003
IEA
PLAZA Integrative Orthologymodification by symbiont of host morphology or physiology AT4G00660
GO:0035195
IEA
PLAZA Integrative Orthologygene silencing by miRNA FBgn0004419
GO:0035194
IEA
PLAZA Integrative Orthologyposttranscriptional gene silencing by RNA FBgn0004419
GO:0010972
IEA
PLAZA Integrative Orthologynegative regulation of G2/M transition of mitotic cell cycle FBgn0004419
GO:0050877
IEA
PLAZA Integrative Orthologynervous system process FBgn0004419
GO:0017148
IEA
PLAZA Integrative Orthologynegative regulation of translation YDL160C
GO:0051726
IEA
PLAZA Integrative Orthologyregulation of cell cycle FBgn0004419
GO:0019048
IEA
PLAZA Integrative Orthologymodulation by virus of host morphology or physiology AT4G00660
GO:0051607
IEA
PLAZA Integrative Orthologydefense response to virus FBgn0004419
GO:0006915
IEA
PLAZA Integrative Orthologyapoptotic process WBGene00000479
GO:0044087
IEA
PLAZA Integrative Orthologyregulation of cellular component biogenesis YDL160C
GO:0003008
IEA
PLAZA Integrative Orthologysystem process FBgn0004419
GO:0002831
IEA
PLAZA Integrative Orthologyregulation of response to biotic stimulus FBgn0004419
GO:1902749
IEA
PLAZA Integrative Orthologyregulation of cell cycle G2/M phase transition FBgn0004419
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction FBgn0004419
GO:0007611
IEA
PLAZA Integrative Orthologylearning or memory FBgn0004419
GO:0007610
IEA
PLAZA Integrative Orthologybehavior FBgn0004419
GO:0002682
IEA
PLAZA Integrative Orthologyregulation of immune system process FBgn0004419
GO:0008306
IEA
PLAZA Integrative Orthologyassociative learning FBgn0004419
GO:0006006
IEA
PLAZA Integrative Orthologyglucose metabolic process FBgn0004419
GO:0007612
IEA
PLAZA Integrative Orthologylearning FBgn0004419
GO:1902115
IEA
PLAZA Integrative Orthologyregulation of organelle assembly YDL160C
GO:0051172
IEA
PLAZA Integrative Orthologynegative regulation of nitrogen compound metabolic process YDL160C
GO:1903047
IEA
PLAZA Integrative Orthologymitotic cell cycle process FBgn0004419
GO:1902750
IEA
PLAZA Integrative Orthologynegative regulation of cell cycle G2/M phase transition FBgn0004419
GO:0019318
IEA
PLAZA Integrative Orthologyhexose metabolic process FBgn0004419
GO:0007292
IEA
PLAZA Integrative Orthologyfemale gamete generation FBgn0004419
GO:0031324
IEA
PLAZA Integrative Orthologynegative regulation of cellular metabolic process YDL160C
GO:0090328
IEA
PLAZA Integrative Orthologyregulation of olfactory learning FBgn0004419
GO:0031047
IEA
PLAZA Integrative Orthologygene silencing by RNA FBgn0004419
GO:0051716
IEA
PLAZA Integrative Orthologycellular response to stimulus FBgn0004419
GO:0000290
IEA
PLAZA Integrative Orthologydeadenylation-dependent decapping of nuclear-transcribed mRNA YDL160C
GO:0031327
IEA
PLAZA Integrative Orthologynegative regulation of cellular biosynthetic process YDL160C
GO:0005975
IEA
PLAZA Integrative Orthologycarbohydrate metabolic process FBgn0004419
GO:0040029
IEA
PLAZA Integrative Orthologyregulation of gene expression, epigenetic FBgn0004419
GO:0006950
IEA
PLAZA Integrative Orthologyresponse to stress FBgn0004419
GO:0006952
IEA
PLAZA Integrative Orthologydefense response FBgn0004419
GO:0042048
IEA
PLAZA Integrative Orthologyolfactory behavior FBgn0004419
GO:0043254
IEA
PLAZA Integrative Orthologyregulation of protein complex assembly YDL160C
GO:0031570
IEA
PLAZA Integrative OrthologyDNA integrity checkpoint FBgn0004419
GO:0016458
IEA
PLAZA Integrative Orthologygene silencing FBgn0004419
GO:0032269
IEA
PLAZA Integrative Orthologynegative regulation of cellular protein metabolic process YDL160C
GO:0051701
IEA
PLAZA Integrative Orthologyinteraction with host AT4G00660
GO:0031572
IEA
PLAZA Integrative OrthologyG2 DNA damage checkpoint FBgn0004419
GO:0002697
IEA
PLAZA Integrative Orthologyregulation of immune effector process FBgn0004419
GO:0000278
IEA
PLAZA Integrative Orthologymitotic cell cycle FBgn0004419
GO:0007635
IEA
PLAZA Integrative Orthologychemosensory behavior FBgn0004419
GO:0002066
IEA
PLAZA Integrative Orthologycolumnar/cuboidal epithelial cell development FBgn0004419
GO:0060429
IEA
PLAZA Integrative Orthologyepithelium development FBgn0004419
GO:0002065
IEA
PLAZA Integrative Orthologycolumnar/cuboidal epithelial cell differentiation FBgn0004419
GO:0002064
IEA
PLAZA Integrative Orthologyepithelial cell development FBgn0004419
GO:0009653
IEA
PLAZA Integrative Orthologyanatomical structure morphogenesis FBgn0004419
GO:0044057
IEA
PLAZA Integrative Orthologyregulation of system process FBgn0004419
GO:0060548
IEA
PLAZA Integrative Orthologynegative regulation of cell death WBGene00000479
GO:0045786
IEA
PLAZA Integrative Orthologynegative regulation of cell cycle FBgn0004419
GO:0009890
IEA
PLAZA Integrative Orthologynegative regulation of biosynthetic process YDL160C
GO:0051707
IEA
PLAZA Integrative Orthologyresponse to other organism FBgn0004419
GO:0050688
IEA
PLAZA Integrative Orthologyregulation of defense response to virus FBgn0004419
GO:0035821
IEA
PLAZA Integrative Orthologymodification of morphology or physiology of other organism AT4G00660
GO:0010389
IEA
PLAZA Integrative Orthologyregulation of G2/M transition of mitotic cell cycle FBgn0004419
GO:0031347
IEA
PLAZA Integrative Orthologyregulation of defense response FBgn0004419
GO:0010941
IEA
PLAZA Integrative Orthologyregulation of cell death WBGene00000479
GO:0000075
IEA
PLAZA Integrative Orthologycell cycle checkpoint FBgn0004419
GO:0006448
IEA
PLAZA Integrative Orthologyregulation of translational elongation YDL160C
GO:0010948
IEA
PLAZA Integrative Orthologynegative regulation of cell cycle process FBgn0004419
GO:0000077
IEA
PLAZA Integrative OrthologyDNA damage checkpoint FBgn0004419
GO:0002376
IEA
PLAZA Integrative Orthologyimmune system process FBgn0004419
GO:0006974
IEA
PLAZA Integrative Orthologycellular response to DNA damage stimulus FBgn0004419
GO:0002252
IEA
PLAZA Integrative Orthologyimmune effector process FBgn0004419
GO:0008355
IEA
PLAZA Integrative Orthologyolfactory learning FBgn0004419
GO:0048646
IEA
PLAZA Integrative Orthologyanatomical structure formation involved in morphogenesis FBgn0004419
GO:0045930
IEA
PLAZA Integrative Orthologynegative regulation of mitotic cell cycle FBgn0004419
GO:0062012
IEA
PLAZA Integrative Orthologyregulation of small molecule metabolic process FBgn0004419
GO:1901991
IEA
PLAZA Integrative Orthologynegative regulation of mitotic cell cycle phase transition FBgn0004419
GO:0051817
IEA
PLAZA Integrative Orthologymodification of morphology or physiology of other organism involved in symbiotic interaction AT4G00660
GO:1901990
IEA
PLAZA Integrative Orthologyregulation of mitotic cell cycle phase transition FBgn0004419
GO:0034063
IEA
PLAZA Integrative Orthologystress granule assembly YDL160C
GO:0051128
IEA
PLAZA Integrative Orthologyregulation of cellular component organization YDL160C
GO:0051248
IEA
PLAZA Integrative Orthologynegative regulation of protein metabolic process YDL160C
GO:0010259
IEA
PLAZA Integrative Orthologymulticellular organism aging WBGene00000479
GO:2000113
IEA
PLAZA Integrative Orthologynegative regulation of cellular macromolecule biosynthetic process YDL160C
GO:0030707
IEA
PLAZA Integrative Orthologyovarian follicle cell development FBgn0004419
GO:0008219
IEA
PLAZA Integrative Orthologycell death WBGene00000479
GO:0044281
IEA
PLAZA Integrative Orthologysmall molecule metabolic process FBgn0004419
GO:0050795
IEA
PLAZA Integrative Orthologyregulation of behavior FBgn0004419
GO:1901988
IEA
PLAZA Integrative Orthologynegative regulation of cell cycle phase transition FBgn0004419
GO:0005996
IEA
PLAZA Integrative Orthologymonosaccharide metabolic process FBgn0004419
GO:1901987
IEA
PLAZA Integrative Orthologyregulation of cell cycle phase transition FBgn0004419
GO:0043069
IEA
PLAZA Integrative Orthologynegative regulation of programmed cell death WBGene00000479
GO:0043067
IEA
PLAZA Integrative Orthologyregulation of programmed cell death WBGene00000479
GO:0080134
IEA
PLAZA Integrative Orthologyregulation of response to stress FBgn0004419
GO:0022402
IEA
PLAZA Integrative Orthologycell cycle process FBgn0004419
GO:0008340
IEA
PLAZA Integrative Orthologydetermination of adult lifespan WBGene00000479
GO:0044839
IEA
PLAZA Integrative Orthologycell cycle G2/M phase transition FBgn0004419
GO:0007093
IEA
PLAZA Integrative Orthologymitotic cell cycle checkpoint FBgn0004419
GO:0007095
IEA
PLAZA Integrative Orthologymitotic G2 DNA damage checkpoint FBgn0004419
GO:0043900
IEA
PLAZA Integrative Orthologyregulation of multi-organism process FBgn0004419

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0045296
IDA
Genome Projectcadherin binding
GO:0045296
Gene Ontologycadherin binding3
GO:0019904
IPI
Genome Projectprotein domain specific binding
GO:0019904
IPI
Gene Ontologyprotein domain specific binding4
GO:0005524
IEA
Genome ProjectATP binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0004386
TAS
Genome Projecthelicase activity
GO:0004386
TAS
Gene Ontologyhelicase activity19 20
GO:0004004
IBA
Genome ProjectATP-dependent RNA helicase activity
GO:0003724
TAS
Genome ProjectRNA helicase activity
GO:0003724
TAS
Gene OntologyRNA helicase activity20
GO:0003723
IDA
Genome ProjectRNA binding
GO:0003723
Gene OntologyRNA binding21 22
GO:0090079
IEA
PLAZA Integrative Orthologytranslation regulator activity, nucleic acid binding YDL160C
GO:0045182
IEA
PLAZA Integrative Orthologytranslation regulator activity YDL160C
GO:0003682
IEA
PLAZA Integrative Orthologychromatin binding YDL160C
GO:0003729
IEA
PLAZA Integrative OrthologymRNA binding AT3G61240

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0097227
IEA
Genome Projectsperm annulus
GO:0043186
IEA
Genome ProjectP granule
GO:0016442
IDA
Genome ProjectRISC complex
GO:0016442
IDA
Gene OntologyRISC complex12
GO:0016020
IDA
Genome Projectmembrane
GO:0016020
Gene Ontologymembrane23
GO:0010494
IDA
Genome Projectcytoplasmic stress granule
GO:0010494
IDA
Gene Ontologycytoplasmic stress granule8 16
GO:0005829
IDA
TAS
Genome Projectcytosol
GO:0005829
IDA
TAS
Gene Ontologycytosol
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005737
IDA
Gene Ontologycytoplasm16
GO:0005730
IEA
Genome Projectnucleolus
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus16
GO:0001520
IEA
Genome Projectouter dense fiber
GO:0000932
IDA, IMP
Genome ProjectP-body
GO:0000932
IDA, IMP
Gene OntologyP-body1 2 6 12 24 25
GO:0000792
IEA
Genome Projectheterochromatin
GO:0036464
IDA
Gene Ontologycytoplasmic ribonucleoprotein granule
GO:0044425
IEA
PLAZA Integrative Orthologymembrane part YDL160C
GO:0015630
IEA
PLAZA Integrative Orthologymicrotubule cytoskeleton FBgn0004419
GO:0098562
IEA
PLAZA Integrative Orthologycytoplasmic side of membrane YDL160C
GO:0098552
IEA
PLAZA Integrative Orthologyside of membrane YDL160C
GO:1990124
IEA
PLAZA Integrative Orthologymessenger ribonucleoprotein complex WBGene00000479
GO:0005875
IEA
PLAZA Integrative Orthologymicrotubule associated complex FBgn0004419

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000629ATP-dependent RNA helicase DEAD-box, conserved site
IPR001650Helicase, C-terminal
IPR011545DEAD/DEAH box helicase domain
IPR014001Helicase superfamily 1/2, ATP-binding domain
IPR014014RNA helicase, DEAD-box type, Q motif
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.
KeggID Description
K12614DDX6, RCK, DHH1; ATP-dependent RNA helicase DDX6/DHH1 [EC:3.6.4.13]
No chloroplast target sequence found.