Gene: ENSG00000109270 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000109270
Transcript Identifier
ENST00000499666
Gene Type
Coding gene
Location
4 : 99881994-99893963 : negative

Family Information

Homologous gene family
HOM02SEM024344
(3 genes in 3 species)
specific family
Orthologous gene family
ORTHO02SEM019871
(2 genes in 2 species)
specific family

Descriptions

gene_descr
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3

Identifiers

Type Value
pidENSP00000424183
HGNC15606
UniprotQ9UHA4
RefSeq_mRNANM_021970.3
EMBLAF130115
EMBLAF201947
EMBLAK311755
EMBLAL544981
EMBLAP001962
EMBLBC026245
EMBLCH471057

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0071230
IMP
Genome Projectcellular response to amino acid stimulus
GO:0071230
IMP
Gene Ontologycellular response to amino acid stimulus1
GO:0043547
IEA
Genome Projectpositive regulation of GTPase activity
GO:0043312
TAS
Genome Projectneutrophil degranulation
GO:0043312
TAS
Gene Ontologyneutrophil degranulation
GO:0034613
IMP
Genome Projectcellular protein localization
GO:0034613
IMP
Gene Ontologycellular protein localization1
GO:0032008
IMP
Genome Projectpositive regulation of TOR signaling
GO:0032008
IMP
Gene Ontologypositive regulation of TOR signaling1
GO:0016241
TAS
Genome Projectregulation of macroautophagy
GO:0016241
TAS
Gene Ontologyregulation of macroautophagy
GO:0007050
TAS
Genome Projectcell cycle arrest
GO:0007050
TAS
Gene Ontologycell cycle arrest
GO:0000186
IEA
Genome Projectactivation of MAPKK activity
GO:0000165
TAS
Genome ProjectMAPK cascade
GO:0000165
TAS
Gene OntologyMAPK cascade

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0032947
IDA
Genome Projectprotein-containing complex scaffold activity
GO:0032947
IDA
Gene Ontologyprotein-containing complex scaffold activity2
GO:0005085
IDA
Genome Projectguanyl-nucleotide exchange factor activity
GO:0005085
IDA
Gene Ontologyguanyl-nucleotide exchange factor activity2
GO:0019209
IEA
Genome Projectkinase activator activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 2 3 4 5 6

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0071986
IDA
Genome ProjectRagulator complex
GO:0071986
IDA
Gene OntologyRagulator complex1
GO:0070821
TAS
Genome Projecttertiary granule membrane
GO:0070821
TAS
Gene Ontologytertiary granule membrane
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0070062
Gene Ontologyextracellular exosome7
GO:0035579
TAS
Genome Projectspecific granule membrane
GO:0035579
TAS
Gene Ontologyspecific granule membrane
GO:0010008
TAS
Genome Projectendosome membrane
GO:0010008
TAS
Gene Ontologyendosome membrane
GO:0005925
IDA
Genome Projectfocal adhesion
GO:0005925
Gene Ontologyfocal adhesion8
GO:0005886
TAS
Genome Projectplasma membrane
GO:0005886
TAS
Gene Ontologyplasma membrane
GO:0005765
TAS
Genome Projectlysosomal membrane
GO:0005765
TAS
Gene Ontologylysosomal membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR015019Ragulator complex protein LAMTOR3

No MapMan annotations defined for this gene.
KeggID Description
K04370LAMTOR3, MP1, MAP2K1IP1; ragulator complex protein LAMTOR3
No chloroplast target sequence found.