Gene: ENSG00000108405 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000108405
Transcript Identifier
ENST00000225538
Gene Type
Coding gene
Location
17 : 3897814-3916225 : negative

Family Information

Homologous gene family
HOM02SEM011341
(8 genes in 1 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
purinergic receptor P2X, ligand gated ion channel, 1

Identifiers

Type Value
pidENSP00000225538
HGNC8533
UniprotP51575
RefSeq_mRNANM_002558.3
EMBLCHEMBL2094
EMBLAF020498
EMBLAF177472
EMBLBC044657
EMBLU45448
EMBLX83688

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0098655
IEA
Genome Projectcation transmembrane transport
GO:0060079
IEA
Genome Projectexcitatory postsynaptic potential
GO:0051924
IEA
Genome Projectregulation of calcium ion transport
GO:0051291
IEA
Genome Projectprotein heterooligomerization
GO:0051260
IEA
Genome Projectprotein homooligomerization
GO:0046513
IEA
Genome Projectceramide biosynthetic process
GO:0043312
TAS
Genome Projectneutrophil degranulation
GO:0043312
TAS
Gene Ontologyneutrophil degranulation
GO:0043270
IEA
Genome Projectpositive regulation of ion transport
GO:0042310
IEA
Genome Projectvasoconstriction
GO:0035590
IEA
Genome Projectpurinergic nucleotide receptor signaling pathway
GO:0035249
IEA
Genome Projectsynaptic transmission, glutamatergic
GO:0033198
IEA
Genome Projectresponse to ATP
GO:0030168
IEA
Genome Projectplatelet activation
GO:0019228
IEA
Genome Projectneuronal action potential
GO:0008217
IEA
Genome Projectregulation of blood pressure
GO:0007596
TAS
Genome Projectblood coagulation
GO:0007596
TAS
Gene Ontologyblood coagulation
GO:0007320
IEA
Genome Projectinsemination
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007165
TAS
Gene Ontologysignal transduction1
GO:0006919
IEA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006915
IEA
Genome Projectapoptotic process
GO:0006811
IDA
Genome Projection transport
GO:0006811
IDA
Gene Ontologyion transport2
GO:0006810
TAS
Genome Projecttransport
GO:0003056
IEA
Genome Projectregulation of vascular smooth muscle contraction
GO:0002554
IEA
Genome Projectserotonin secretion by platelet
GO:0019932
IEA
PLAZA Homology (enrichment)second-messenger-mediated signaling HOM02SEM011341
GO:0030003
IEA
PLAZA Homology (enrichment)cellular cation homeostasis HOM02SEM011341
GO:0019722
IEA
PLAZA Homology (enrichment)calcium-mediated signaling HOM02SEM011341
GO:0072507
IEA
PLAZA Homology (enrichment)divalent inorganic cation homeostasis HOM02SEM011341
GO:0010524
IEA
PLAZA Homology (enrichment)positive regulation of calcium ion transport into cytosol HOM02SEM011341
GO:0050801
IEA
PLAZA Homology (enrichment)ion homeostasis HOM02SEM011341
GO:0010522
IEA
PLAZA Homology (enrichment)regulation of calcium ion transport into cytosol HOM02SEM011341
GO:0072503
IEA
PLAZA Homology (enrichment)cellular divalent inorganic cation homeostasis HOM02SEM011341
GO:0098771
IEA
PLAZA Homology (enrichment)inorganic ion homeostasis HOM02SEM011341
GO:0006874
IEA
PLAZA Homology (enrichment)cellular calcium ion homeostasis HOM02SEM011341
GO:0007204
IEA
PLAZA Homology (enrichment)positive regulation of cytosolic calcium ion concentration HOM02SEM011341
GO:0006873
IEA
PLAZA Homology (enrichment)cellular ion homeostasis HOM02SEM011341
GO:0055080
IEA
PLAZA Homology (enrichment)cation homeostasis HOM02SEM011341
GO:0060402
IEA
PLAZA Homology (enrichment)calcium ion transport into cytosol HOM02SEM011341
GO:0060401
IEA
PLAZA Homology (enrichment)cytosolic calcium ion transport HOM02SEM011341
GO:0006875
IEA
PLAZA Homology (enrichment)cellular metal ion homeostasis HOM02SEM011341
GO:0051480
IEA
PLAZA Homology (enrichment)regulation of cytosolic calcium ion concentration HOM02SEM011341
GO:0051928
IEA
PLAZA Homology (enrichment)positive regulation of calcium ion transport HOM02SEM011341
GO:0055065
IEA
PLAZA Homology (enrichment)metal ion homeostasis HOM02SEM011341
GO:0055074
IEA
PLAZA Homology (enrichment)calcium ion homeostasis HOM02SEM011341
GO:0055082
IEA
PLAZA Homology (enrichment)cellular chemical homeostasis HOM02SEM011341

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0008144
IEA
Genome Projectdrug binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0005261
IDA
Genome Projectcation channel activity
GO:0005261
IDA
Gene Ontologycation channel activity2
GO:0004931
IBA
Genome Projectextracellularly ATP-gated cation channel activity
GO:0001614
IDA
Genome Projectpurinergic nucleotide receptor activity
GO:0001614
IDA
Gene Ontologypurinergic nucleotide receptor activity2

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0045211
IEA
Genome Projectpostsynaptic membrane
GO:0045121
IEA
Genome Projectmembrane raft
GO:0043005
IEA
Genome Projectneuron projection
GO:0035579
TAS
Genome Projectspecific granule membrane
GO:0035579
TAS
Gene Ontologyspecific granule membrane
GO:0030667
TAS
Genome Projectsecretory granule membrane
GO:0030667
TAS
Gene Ontologysecretory granule membrane
GO:0005887
IEA
Genome Projectintegral component of plasma membrane
GO:0005887
TAS
Gene Ontologyintegral component of plasma membrane1
GO:0005886
TAS
Genome Projectplasma membrane
GO:0005886
TAS
Gene Ontologyplasma membrane
GO:0005639
IBA
Genome Projectintegral component of nuclear inner membrane
GO:0044297
IEA
PLAZA Homology (enrichment)cell body HOM02SEM011341
GO:0043025
IEA
PLAZA Homology (enrichment)neuronal cell body HOM02SEM011341
GO:0036477
IEA
PLAZA Homology (enrichment)somatodendritic compartment HOM02SEM011341

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001429P2X purinoreceptor
IPR003044P2X1 purinoceptor
IPR027309P2X purinoreceptor extracellular domain superfamily

No MapMan annotations defined for this gene.
KeggID Description
K05215P2RX1; P2X purinoceptor 1
No chloroplast target sequence found.