Gene: ENSG00000108387 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000108387
Transcript Identifier
ENST00000457347
Gene Type
Coding gene
Location
17 : 58520426-58540673 : negative

Family Information

Homologous gene family
HOM02SEM001085
(47 genes in 9 species)
specific family

Descriptions

gene_descr
septin 4

Identifiers

Type Value
pidENSP00000402000
HGNC9165
UniprotO43236
RefSeq_mRNANM_001256782.1

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:2001244
IMP
Genome Projectpositive regulation of intrinsic apoptotic signaling pathway
GO:2001244
IMP
Gene Ontologypositive regulation of intrinsic apoptotic signaling pathway1
GO:0051301
IEA
Genome Projectcell division
GO:0051260
IMP
Genome Projectprotein homooligomerization
GO:0051260
IMP
Gene Ontologyprotein homooligomerization2
GO:0048240
IEA
Genome Projectsperm capacitation
GO:0043065
IDA
Genome Projectpositive regulation of apoptotic process
GO:0043065
IDA
Gene Ontologypositive regulation of apoptotic process1
GO:0042981
NAS
Genome Projectregulation of apoptotic process
GO:0042981
NAS
Gene Ontologyregulation of apoptotic process3
GO:0031398
IDA
Genome Projectpositive regulation of protein ubiquitination
GO:0031398
IDA
Gene Ontologypositive regulation of protein ubiquitination1
GO:0030382
IEA
Genome Projectsperm mitochondrion organization
GO:0007420
IEA
Genome Projectbrain development
GO:0007049
IEA
Genome Projectcell cycle
GO:0006915
NAS
Genome Projectapoptotic process
GO:0006915
NAS
Gene Ontologyapoptotic process3
GO:0030435
IEA
PLAZA Integrative Orthologysporulation resulting in formation of a cellular spore SPBC19F8.01c
GO:0090529
IEA
PLAZA Integrative Orthologycell septum assembly YDL225W
GO:0030036
IEA
PLAZA Integrative Orthologyactin cytoskeleton organization YDL225W
GO:0010562
IEA
PLAZA Integrative Orthologypositive regulation of phosphorus metabolic process YJR076C
GO:0030437
IEA
PLAZA Integrative Orthologyascospore formation SPBC19F8.01c
GO:0022411
IEA
PLAZA Integrative Orthologycellular component disassembly YLR314C
GO:0000921
IEA
PLAZA Integrative Orthologyseptin ring assembly SPBC16A3.01
GO:0022413
IEA
PLAZA Integrative Orthologyreproductive process in single-celled organism SPBC19F8.01c
GO:0032185
IEA
PLAZA Integrative Orthologyseptin cytoskeleton organization SPBC16A3.01
GO:0007163
IEA
PLAZA Integrative Orthologyestablishment or maintenance of cell polarity YJR076C
GO:0032186
IEA
PLAZA Integrative Orthologycellular bud neck septin ring organization YDL225W
GO:0061024
IEA
PLAZA Integrative Orthologymembrane organization SPBC19F8.01c
GO:0051347
IEA
PLAZA Integrative Orthologypositive regulation of transferase activity YJR076C
GO:0016310
IEA
PLAZA Integrative Orthologyphosphorylation YJR076C
GO:0033674
IEA
PLAZA Integrative Orthologypositive regulation of kinase activity YJR076C
GO:0033036
IEA
PLAZA Integrative Orthologymacromolecule localization SPAC4F10.11
GO:0000082
IEA
PLAZA Integrative OrthologyG1/S transition of mitotic cell cycle YDL225W
GO:0032505
IEA
PLAZA Integrative Orthologyreproduction of a single-celled organism SPBC19F8.01c
GO:0032989
IEA
PLAZA Integrative Orthologycellular component morphogenesis SPBC19F8.01c
GO:0032506
IEA
PLAZA Integrative Orthologycytokinetic process YDL225W
GO:0097271
IEA
PLAZA Integrative Orthologyprotein localization to bud neck YJR076C
GO:0006468
IEA
PLAZA Integrative Orthologyprotein phosphorylation YJR076C
GO:0044772
IEA
PLAZA Integrative Orthologymitotic cell cycle phase transition YDL225W
GO:0000910
IEA
PLAZA Integrative Orthologycytokinesis SPBC16A3.01
GO:0000915
IEA
PLAZA Integrative Orthologyactomyosin contractile ring assembly YDL225W
GO:0000912
IEA
PLAZA Integrative Orthologyassembly of actomyosin apparatus involved in cytokinesis YDL225W
GO:0044091
IEA
PLAZA Integrative Orthologymembrane biogenesis SPBC19F8.01c
GO:0000917
IEA
PLAZA Integrative Orthologydivision septum assembly YDL225W
GO:0051338
IEA
PLAZA Integrative Orthologyregulation of transferase activity YJR076C
GO:0044770
IEA
PLAZA Integrative Orthologycell cycle phase transition YDL225W
GO:0051174
IEA
PLAZA Integrative Orthologyregulation of phosphorus metabolic process YJR076C
GO:0045860
IEA
PLAZA Integrative Orthologypositive regulation of protein kinase activity YJR076C
GO:0044093
IEA
PLAZA Integrative Orthologypositive regulation of molecular function YJR076C
GO:0051179
IEA
PLAZA Integrative Orthologylocalization SPAC4F10.11
GO:0007105
IEA
PLAZA Integrative Orthologycytokinesis, site selection YDL225W
GO:0031032
IEA
PLAZA Integrative Orthologyactomyosin structure organization YDL225W
GO:0032120
IEA
PLAZA Integrative Orthologyascospore-type prospore membrane assembly SPBC19F8.01c
GO:0061640
IEA
PLAZA Integrative Orthologycytoskeleton-dependent cytokinesis SPBC16A3.01
GO:0045859
IEA
PLAZA Integrative Orthologyregulation of protein kinase activity YJR076C
GO:0010458
IEA
PLAZA Integrative Orthologyexit from mitosis YDL225W
GO:0048285
IEA
PLAZA Integrative Orthologyorganelle fission YDL225W
GO:0051321
IEA
PLAZA Integrative Orthologymeiotic cell cycle SPBC19F8.01c
GO:0030866
IEA
PLAZA Integrative Orthologycortical actin cytoskeleton organization YDL225W
GO:0030865
IEA
PLAZA Integrative Orthologycortical cytoskeleton organization YDL225W
GO:1903046
IEA
PLAZA Integrative Orthologymeiotic cell cycle process SPBC19F8.01c
GO:1903047
IEA
PLAZA Integrative Orthologymitotic cell cycle process SPBC16A3.01
GO:0070925
IEA
PLAZA Integrative Orthologyorganelle assembly SPBC16A3.01
GO:0043549
IEA
PLAZA Integrative Orthologyregulation of kinase activity YJR076C
GO:0031321
IEA
PLAZA Integrative Orthologyascospore-type prospore assembly SPBC19F8.01c
GO:0001934
IEA
PLAZA Integrative Orthologypositive regulation of protein phosphorylation YJR076C
GO:0001932
IEA
PLAZA Integrative Orthologyregulation of protein phosphorylation YJR076C
GO:0010927
IEA
PLAZA Integrative Orthologycellular component assembly involved in morphogenesis SPBC19F8.01c
GO:0042325
IEA
PLAZA Integrative Orthologyregulation of phosphorylation YJR076C
GO:0006796
IEA
PLAZA Integrative Orthologyphosphate-containing compound metabolic process YJR076C
GO:0006793
IEA
PLAZA Integrative Orthologyphosphorus metabolic process YJR076C
GO:0071709
IEA
PLAZA Integrative Orthologymembrane assembly SPBC19F8.01c
GO:0043935
IEA
PLAZA Integrative Orthologysexual sporulation resulting in formation of a cellular spore SPBC19F8.01c
GO:0042327
IEA
PLAZA Integrative Orthologypositive regulation of phosphorylation YJR076C
GO:0043934
IEA
PLAZA Integrative Orthologysporulation SPBC19F8.01c
GO:0140014
IEA
PLAZA Integrative Orthologymitotic nuclear division YDL225W
GO:0000280
IEA
PLAZA Integrative Orthologynuclear division YDL225W
GO:0070583
IEA
PLAZA Integrative Orthologyspore membrane bending pathway SPBC19F8.01c
GO:0019220
IEA
PLAZA Integrative Orthologyregulation of phosphate metabolic process YJR076C
GO:0000281
IEA
PLAZA Integrative Orthologymitotic cytokinesis SPBC16A3.01
GO:0000278
IEA
PLAZA Integrative Orthologymitotic cell cycle SPBC16A3.01
GO:0009653
IEA
PLAZA Integrative Orthologyanatomical structure morphogenesis SPBC19F8.01c
GO:0034613
IEA
PLAZA Integrative Orthologycellular protein localization SPAC4F10.11
GO:0034293
IEA
PLAZA Integrative Orthologysexual sporulation SPBC19F8.01c
GO:0031106
IEA
PLAZA Integrative Orthologyseptin ring organization SPBC16A3.01
GO:0030011
IEA
PLAZA Integrative Orthologymaintenance of cell polarity YJR076C
GO:0031107
IEA
PLAZA Integrative Orthologyseptin ring disassembly YLR314C
GO:0043085
IEA
PLAZA Integrative Orthologypositive regulation of catalytic activity YJR076C
GO:0065009
IEA
PLAZA Integrative Orthologyregulation of molecular function YJR076C
GO:0044843
IEA
PLAZA Integrative Orthologycell cycle G1/S phase transition YDL225W
GO:0007029
IEA
PLAZA Integrative Orthologyendoplasmic reticulum organization YDL225W
GO:0061163
IEA
PLAZA Integrative Orthologyendoplasmic reticulum polarization YDL225W
GO:0048646
IEA
PLAZA Integrative Orthologyanatomical structure formation involved in morphogenesis SPBC19F8.01c
GO:0045937
IEA
PLAZA Integrative Orthologypositive regulation of phosphate metabolic process YJR076C
GO:0010256
IEA
PLAZA Integrative Orthologyendomembrane system organization YDL225W
GO:0050790
IEA
PLAZA Integrative Orthologyregulation of catalytic activity YJR076C
GO:0034622
IEA
PLAZA Integrative Orthologycellular protein-containing complex assembly SPBC16A3.01
GO:0051641
IEA
PLAZA Integrative Orthologycellular localization SPAC4F10.11
GO:0030029
IEA
PLAZA Integrative Orthologyactin filament-based process YDL225W
GO:1903008
IEA
PLAZA Integrative Orthologyorganelle disassembly YLR314C
GO:0008104
IEA
PLAZA Integrative Orthologyprotein localization SPAC4F10.11
GO:0022402
IEA
PLAZA Integrative Orthologycell cycle process SPBC16A3.01
GO:0044837
IEA
PLAZA Integrative Orthologyactomyosin contractile ring organization YDL225W
GO:0007010
IEA
PLAZA Integrative Orthologycytoskeleton organization SPBC16A3.01
GO:0070727
IEA
PLAZA Integrative Orthologycellular macromolecule localization SPAC4F10.11

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0042803
IMP
Genome Projectprotein homodimerization activity
GO:0042803
IMP
Gene Ontologyprotein homodimerization activity2
GO:0005525
IMP
Genome ProjectGTP binding
GO:0005525
IMP
Gene OntologyGTP binding2
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding4 5 6
GO:0005198
TAS
Genome Projectstructural molecule activity
GO:0005198
TAS
Gene Ontologystructural molecule activity7
GO:0003924
IMP
Genome ProjectGTPase activity
GO:0003924
IMP
Gene OntologyGTPase activity2
GO:0000287
IMP
Genome Projectmagnesium ion binding
GO:0000287
IMP
Gene Ontologymagnesium ion binding2
GO:0005543
IEA
PLAZA Integrative Orthologyphospholipid binding YJR076C
GO:0010314
IEA
PLAZA Integrative Orthologyphosphatidylinositol-5-phosphate binding YJR076C
GO:0035091
IEA
PLAZA Integrative Orthologyphosphatidylinositol binding YJR076C
GO:0032947
IEA
PLAZA Integrative Orthologyprotein-containing complex scaffold activity YHR107C
GO:0008289
IEA
PLAZA Integrative Orthologylipid binding YJR076C
GO:0070273
IEA
PLAZA Integrative Orthologyphosphatidylinositol-4-phosphate binding YJR076C
GO:1901981
IEA
PLAZA Integrative Orthologyphosphatidylinositol phosphate binding YJR076C

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0097227
IDA
Genome Projectsperm annulus
GO:0097227
IDA
Gene Ontologysperm annulus5
GO:0043209
IEA
Genome Projectmyelin sheath
GO:0031105
IDA, IMP
Genome Projectseptin complex
GO:0031105
IDA, IMP
Gene Ontologyseptin complex2 5
GO:0005739
NAS
Genome Projectmitochondrion
GO:0005739
NAS
Gene Ontologymitochondrion3
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005654
IDA
Gene Ontologynucleoplasm
GO:0005634
NAS
Genome Projectnucleus
GO:0005634
NAS
Gene Ontologynucleus3
GO:0005819
IEA
PLAZA Integrative Orthologyspindle YJR076C
GO:0030312
IEA
PLAZA Integrative Orthologyexternal encapsulating structure YJR076C
GO:0099738
IEA
PLAZA Integrative Orthologycell cortex region SPBC16A3.01
GO:0005935
IEA
PLAZA Integrative Orthologycellular bud neck YJR076C
GO:0005937
IEA
PLAZA Integrative Orthologymating projection YJR076C
GO:0005933
IEA
PLAZA Integrative Orthologycellular bud YJR076C
GO:0005940
IEA
PLAZA Integrative Orthologyseptin ring SPBC16A3.01
GO:0044426
IEA
PLAZA Integrative Orthologycell wall part YHR107C
GO:0042763
IEA
PLAZA Integrative Orthologyintracellular immature spore YJR076C
GO:0042764
IEA
PLAZA Integrative Orthologyascospore-type prospore YJR076C
GO:0043332
IEA
PLAZA Integrative Orthologymating projection tip YJR076C
GO:0031097
IEA
PLAZA Integrative Orthologymedial cortex SPBC16A3.01
GO:0070938
IEA
PLAZA Integrative Orthologycontractile ring SPBC16A3.01
GO:0072687
IEA
PLAZA Integrative Orthologymeiotic spindle YJR076C
GO:0036391
IEA
PLAZA Integrative Orthologymedial cortex septin ring SPBC16A3.01
GO:0099513
IEA
PLAZA Integrative Orthologypolymeric cytoskeletal fiber YJR076C
GO:0099512
IEA
PLAZA Integrative Orthologysupramolecular fiber YJR076C
GO:0099081
IEA
PLAZA Integrative Orthologysupramolecular polymer YJR076C
GO:0099080
IEA
PLAZA Integrative Orthologysupramolecular complex YJR076C
GO:0030864
IEA
PLAZA Integrative Orthologycortical actin cytoskeleton SPBC16A3.01
GO:0030863
IEA
PLAZA Integrative Orthologycortical cytoskeleton SPBC16A3.01
GO:0015629
IEA
PLAZA Integrative Orthologyactin cytoskeleton SPBC16A3.01
GO:0005829
IEA
PLAZA Integrative Orthologycytosol SPBC16A3.01
GO:0051286
IEA
PLAZA Integrative Orthologycell tip YJR076C
GO:0005826
IEA
PLAZA Integrative Orthologyactomyosin contractile ring SPBC16A3.01
GO:0000144
IEA
PLAZA Integrative Orthologycellular bud neck septin ring YJR076C
GO:0015630
IEA
PLAZA Integrative Orthologymicrotubule cytoskeleton YJR076C
GO:0031160
IEA
PLAZA Integrative Orthologyspore wall YJR076C
GO:0005618
IEA
PLAZA Integrative Orthologycell wall YJR076C
GO:0005619
IEA
PLAZA Integrative Orthologyascospore wall YJR076C
GO:0005621
IEA
PLAZA Integrative Orthologycellular bud scar YHR107C
GO:0044462
IEA
PLAZA Integrative Orthologyexternal encapsulating structure part YHR107C
GO:0000399
IEA
PLAZA Integrative Orthologycellular bud neck septin structure YJR076C
GO:0001400
IEA
PLAZA Integrative Orthologymating projection base YJR076C
GO:0032153
IEA
PLAZA Integrative Orthologycell division site SPBC16A3.01
GO:0032151
IEA
PLAZA Integrative Orthologymitotic septin complex SPBC16A3.01
GO:0032155
IEA
PLAZA Integrative Orthologycell division site part SPBC16A3.01
GO:0005876
IEA
PLAZA Integrative Orthologyspindle microtubule YJR076C
GO:0005881
IEA
PLAZA Integrative Orthologycytoplasmic microtubule YJR076C
GO:0032161
IEA
PLAZA Integrative Orthologycleavage apparatus septin structure SPBC16A3.01
GO:0120104
IEA
PLAZA Integrative Orthologyactomyosin contractile ring, proximal layer SPBC16A3.01
GO:0032160
IEA
PLAZA Integrative Orthologyseptin filament array YJR076C
GO:0005628
IEA
PLAZA Integrative Orthologyprospore membrane YJR076C
GO:0030427
IEA
PLAZA Integrative Orthologysite of polarized growth YJR076C
GO:0005874
IEA
PLAZA Integrative Orthologymicrotubule YJR076C
GO:0009277
IEA
PLAZA Integrative Orthologyfungal-type cell wall YJR076C

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR016491Septin
IPR027417P-loop containing nucleoside triphosphate hydrolase
IPR030379Septin-type guanine nucleotide-binding (G) domain
IPR030643Septin 4

No MapMan annotations defined for this gene.
KeggID Description
K16943SEPT4; septin 4
No chloroplast target sequence found.