Gene: ENSG00000105707 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000105707
Transcript Identifier
ENST00000392226
Gene Type
Coding gene
Location
19 : 35042507-35066287 : positive

Family Information

Homologous gene family
HOM02SEM000009
(875 genes in 18 species)
specific family
Orthologous gene family
ORTHO02SEM000010
(778 genes in 18 species)
specific family

Descriptions

gene_descr
hepsin

Identifiers

Type Value
pidENSP00000376060
HGNC5155
UniprotP05981
RefSeq_mRNANM_002151.2
EMBLCHEMBL2079849
EMBLAK315655
EMBLBC025716
EMBLM18930
EMBLX07002
EMBLX07732

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:2000611
ISS
Genome Projectpositive regulation of thyroid hormone generation
GO:2000611
ISS
Gene Ontologypositive regulation of thyroid hormone generation
GO:2000347
IDA
Genome Projectpositive regulation of hepatocyte proliferation
GO:2000347
IDA
Gene Ontologypositive regulation of hepatocyte proliferation1
GO:0097195
ISS
Genome Projectpilomotor reflex
GO:0097195
ISS
Gene Ontologypilomotor reflex
GO:0097066
ISS
Genome Projectresponse to thyroid hormone
GO:0097066
ISS
Gene Ontologyresponse to thyroid hormone
GO:0090103
ISS
Genome Projectcochlea morphogenesis
GO:0090103
ISS
Gene Ontologycochlea morphogenesis
GO:0071805
ISS
Genome Projectpotassium ion transmembrane transport
GO:0071805
ISS
Gene Ontologypotassium ion transmembrane transport
GO:0050910
ISS
Genome Projectdetection of mechanical stimulus involved in sensory perception of sound
GO:0050910
ISS
Gene Ontologydetection of mechanical stimulus involved in sensory perception of sound
GO:0050680
IDA
Genome Projectnegative regulation of epithelial cell proliferation
GO:0050680
IDA
Gene Ontologynegative regulation of epithelial cell proliferation2
GO:0048012
TAS
Genome Projecthepatocyte growth factor receptor signaling pathway
GO:0048012
TAS
Gene Ontologyhepatocyte growth factor receptor signaling pathway
GO:0043923
IDA
Genome Projectpositive regulation by host of viral transcription
GO:0043923
IDA
Gene Ontologypositive regulation by host of viral transcription1
GO:0043066
IDA
Genome Projectnegative regulation of apoptotic process
GO:0043066
IDA
Gene Ontologynegative regulation of apoptotic process1
GO:0034769
IDA
Genome Projectbasement membrane disassembly
GO:0034769
IDA
Gene Ontologybasement membrane disassembly3
GO:0030307
IMP
Genome Projectpositive regulation of cell growth
GO:0030307
IMP
Gene Ontologypositive regulation of cell growth4
GO:0010756
IDA
Genome Projectpositive regulation of plasminogen activation
GO:0010756
IDA
Gene Ontologypositive regulation of plasminogen activation3
GO:0010719
IDA
Genome Projectnegative regulation of epithelial to mesenchymal transition
GO:0010719
IDA
Gene Ontologynegative regulation of epithelial to mesenchymal transition2
GO:0010628
ISS
Genome Projectpositive regulation of gene expression
GO:0010628
ISS
Gene Ontologypositive regulation of gene expression
GO:0008360
IMP
Genome Projectregulation of cell shape
GO:0008360
IMP
Gene Ontologyregulation of cell shape4
GO:0006508
IDA
Genome Projectproteolysis
GO:0006508
IDA
Gene Ontologyproteolysis2 3 5 6
GO:0050820
IEA
PLAZA Integrative Orthologypositive regulation of coagulation ENSG00000131187
GO:0030431
IEA
PLAZA Integrative Orthologysleep FBgn0036022
GO:0060180
IEA
PLAZA Integrative Orthologyfemale mating behavior FBgn0037036
GO:0010605
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule metabolic process ENSG00000187045
GO:0046693
IEA
PLAZA Integrative Orthologysperm storage FBgn0037036
GO:0019098
IEA
PLAZA Integrative Orthologyreproductive behavior FBgn0037036
GO:0002788
IEA
PLAZA Integrative Orthologyregulation of antifungal peptide production FBgn0030926
GO:0009617
IEA
PLAZA Integrative Orthologyresponse to bacterium FBgn0030051
GO:0002786
IEA
PLAZA Integrative Orthologyregulation of antibacterial peptide production FBgn0039102
GO:0046692
IEA
PLAZA Integrative Orthologysperm competition FBgn0037036
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction ENSG00000100312
GO:0002673
IEA
PLAZA Integrative Orthologyregulation of acute inflammatory response ENSG00000131187
GO:0007320
IEA
PLAZA Integrative Orthologyinsemination FBgn0037036
GO:0009620
IEA
PLAZA Integrative Orthologyresponse to fungus FBgn0030051
GO:0006355
IEA
PLAZA Integrative Orthologyregulation of transcription, DNA-templated ENSG00000187045
GO:0051917
IEA
PLAZA Integrative Orthologyregulation of fibrinolysis ENSG00000131187
GO:0006351
IEA
PLAZA Integrative Orthologytranscription, DNA-templated ENSG00000187045
GO:0051919
IEA
PLAZA Integrative Orthologypositive regulation of fibrinolysis ENSG00000131187
GO:0050829
IEA
PLAZA Integrative Orthologydefense response to Gram-negative bacterium FBgn0030051
GO:0044706
IEA
PLAZA Integrative Orthologymulti-multicellular organism process ENSG00000100312
GO:0044703
IEA
PLAZA Integrative Orthologymulti-organism reproductive process ENSG00000100312
GO:2000331
IEA
PLAZA Integrative Orthologyregulation of terminal button organization FBgn0029827
GO:0034248
IEA
PLAZA Integrative Orthologyregulation of cellular amide metabolic process FBgn0030926
GO:0002778
IEA
PLAZA Integrative Orthologyantibacterial peptide production FBgn0039102
GO:0002777
IEA
PLAZA Integrative Orthologyantimicrobial peptide biosynthetic process FBgn0030926
GO:0032504
IEA
PLAZA Integrative Orthologymulticellular organism reproduction ENSG00000100312
GO:0002775
IEA
PLAZA Integrative Orthologyantimicrobial peptide production FBgn0030926
GO:0009607
IEA
PLAZA Integrative Orthologyresponse to biotic stimulus FBgn0030051
GO:0007309
IEA
PLAZA Integrative Orthologyoocyte axis specification FBgn0000533
GO:0007308
IEA
PLAZA Integrative Orthologyoocyte construction FBgn0000533
GO:0002784
IEA
PLAZA Integrative Orthologyregulation of antimicrobial peptide production FBgn0030926
GO:0002542
IEA
PLAZA Integrative OrthologyFactor XII activation ENSG00000131187
GO:0099174
IEA
PLAZA Integrative Orthologyregulation of presynapse organization FBgn0029827
GO:0002783
IEA
PLAZA Integrative Orthologyantifungal peptide biosynthetic process FBgn0030926
GO:1903900
IEA
PLAZA Integrative Orthologyregulation of viral life cycle ENSG00000184012
GO:0002541
IEA
PLAZA Integrative Orthologyactivation of plasma proteins involved in acute inflammatory response ENSG00000131187
GO:0002781
IEA
PLAZA Integrative Orthologyantifungal peptide production FBgn0030926
GO:1903902
IEA
PLAZA Integrative Orthologypositive regulation of viral life cycle ENSG00000184012
GO:0002780
IEA
PLAZA Integrative Orthologyantibacterial peptide biosynthetic process FBgn0039102
GO:0007310
IEA
PLAZA Integrative Orthologyoocyte dorsal/ventral axis specification FBgn0000533
GO:0099172
IEA
PLAZA Integrative Orthologypresynapse organization FBgn0029827
GO:0007311
IEA
PLAZA Integrative Orthologymaternal specification of dorsal/ventral axis, oocyte, germ-line encoded FBgn0000533
GO:0009611
IEA
PLAZA Integrative Orthologyresponse to wounding ENSG00000131187
GO:0050817
IEA
PLAZA Integrative Orthologycoagulation ENSG00000131187
GO:0006582
IEA
PLAZA Integrative Orthologymelanin metabolic process FBgn0037515
GO:0009056
IEA
PLAZA Integrative Orthologycatabolic process ENSG00000187045
GO:0050819
IEA
PLAZA Integrative Orthologynegative regulation of coagulation ENSG00000131187
GO:0050818
IEA
PLAZA Integrative Orthologyregulation of coagulation ENSG00000131187
GO:0043603
IEA
PLAZA Integrative Orthologycellular amide metabolic process FBgn0030926
GO:0034250
IEA
PLAZA Integrative Orthologypositive regulation of cellular amide metabolic process FBgn0030926
GO:0043604
IEA
PLAZA Integrative Orthologyamide biosynthetic process FBgn0030926
GO:0031424
IEA
PLAZA Integrative Orthologykeratinization ENSG00000142615
GO:0030574
IEA
PLAZA Integrative Orthologycollagen catabolic process ENSG00000187045
GO:0050801
IEA
PLAZA Integrative Orthologyion homeostasis ENSG00000187045
GO:0050803
IEA
PLAZA Integrative Orthologyregulation of synapse structure or activity FBgn0029827
GO:0043043
IEA
PLAZA Integrative Orthologypeptide biosynthetic process FBgn0030926
GO:0072376
IEA
PLAZA Integrative Orthologyprotein activation cascade ENSG00000131187
GO:0072378
IEA
PLAZA Integrative Orthologyblood coagulation, fibrin clot formation ENSG00000131187
GO:0010629
IEA
PLAZA Integrative Orthologynegative regulation of gene expression ENSG00000187045
GO:0030216
IEA
PLAZA Integrative Orthologykeratinocyte differentiation ENSG00000142615
GO:0098542
IEA
PLAZA Integrative Orthologydefense response to other organism FBgn0030051
GO:0042742
IEA
PLAZA Integrative Orthologydefense response to bacterium FBgn0030051
GO:0007585
IEA
PLAZA Integrative Orthologyrespiratory gaseous exchange ENSG00000153802
GO:0007586
IEA
PLAZA Integrative Orthologydigestion ENSG00000142789
GO:0050808
IEA
PLAZA Integrative Orthologysynapse organization FBgn0029827
GO:0007341
IEA
PLAZA Integrative Orthologypenetration of zona pellucida ENSG00000100312
GO:0050807
IEA
PLAZA Integrative Orthologyregulation of synapse organization FBgn0029827
GO:0007340
IEA
PLAZA Integrative Orthologyacrosome reaction ENSG00000100312
GO:0048609
IEA
PLAZA Integrative Orthologymulticellular organismal reproductive process ENSG00000100312
GO:0017144
IEA
PLAZA Integrative Orthologydrug metabolic process ENSG00000162438
GO:0033619
IEA
PLAZA Integrative Orthologymembrane protein proteolysis ENSG00000187045
GO:0098771
IEA
PLAZA Integrative Orthologyinorganic ion homeostasis ENSG00000187045
GO:0042060
IEA
PLAZA Integrative Orthologywound healing ENSG00000131187
GO:0002675
IEA
PLAZA Integrative Orthologypositive regulation of acute inflammatory response ENSG00000131187
GO:0002684
IEA
PLAZA Integrative Orthologypositive regulation of immune system process FBgn0037515
GO:0002440
IEA
PLAZA Integrative Orthologyproduction of molecular mediator of immune response FBgn0030926
GO:0002682
IEA
PLAZA Integrative Orthologyregulation of immune system process FBgn0037515
GO:0042730
IEA
PLAZA Integrative Orthologyfibrinolysis ENSG00000187045
GO:0009994
IEA
PLAZA Integrative Orthologyoocyte differentiation FBgn0000533
GO:0008544
IEA
PLAZA Integrative Orthologyepidermis development ENSG00000142615
GO:0010004
IEA
PLAZA Integrative Orthologygastrulation involving germ band extension FBgn0000533
GO:0019732
IEA
PLAZA Integrative Orthologyantifungal humoral response FBgn0030926
GO:0019730
IEA
PLAZA Integrative Orthologyantimicrobial humoral response FBgn0030926
GO:0019731
IEA
PLAZA Integrative Orthologyantibacterial humoral response FBgn0039102
GO:0019058
IEA
PLAZA Integrative Orthologyviral life cycle ENSG00000184012
GO:0046008
IEA
PLAZA Integrative Orthologyregulation of female receptivity, post-mating FBgn0037036
GO:0055080
IEA
PLAZA Integrative Orthologycation homeostasis ENSG00000187045
GO:0042440
IEA
PLAZA Integrative Orthologypigment metabolic process FBgn0037515
GO:1903035
IEA
PLAZA Integrative Orthologynegative regulation of response to wounding ENSG00000131187
GO:1903034
IEA
PLAZA Integrative Orthologyregulation of response to wounding ENSG00000131187
GO:1903036
IEA
PLAZA Integrative Orthologypositive regulation of response to wounding ENSG00000131187
GO:0019725
IEA
PLAZA Integrative Orthologycellular homeostasis ENSG00000160183
GO:0055082
IEA
PLAZA Integrative Orthologycellular chemical homeostasis ENSG00000160183
GO:0007190
IEA
PLAZA Integrative Orthologyactivation of adenylate cyclase activity ENSG00000100312
GO:0051701
IEA
PLAZA Integrative Orthologyinteraction with host ENSG00000184012
GO:0060429
IEA
PLAZA Integrative Orthologyepithelium development ENSG00000142615
GO:0046598
IEA
PLAZA Integrative Orthologypositive regulation of viral entry into host cell ENSG00000184012
GO:0055078
IEA
PLAZA Integrative Orthologysodium ion homeostasis ENSG00000160183
GO:0051707
IEA
PLAZA Integrative Orthologyresponse to other organism FBgn0030051
GO:0051828
IEA
PLAZA Integrative Orthologyentry into other organism involved in symbiotic interaction ENSG00000184012
GO:0055076
IEA
PLAZA Integrative Orthologytransition metal ion homeostasis ENSG00000187045
GO:0055072
IEA
PLAZA Integrative Orthologyiron ion homeostasis ENSG00000187045
GO:0016125
IEA
PLAZA Integrative Orthologysterol metabolic process ENSG00000142789
GO:0050727
IEA
PLAZA Integrative Orthologyregulation of inflammatory response ENSG00000131187
GO:0002526
IEA
PLAZA Integrative Orthologyacute inflammatory response ENSG00000131187
GO:0046596
IEA
PLAZA Integrative Orthologyregulation of viral entry into host cell ENSG00000184012
GO:0051253
IEA
PLAZA Integrative Orthologynegative regulation of RNA metabolic process ENSG00000187045
GO:1900426
IEA
PLAZA Integrative Orthologypositive regulation of defense response to bacterium FBgn0039102
GO:0061844
IEA
PLAZA Integrative Orthologyantimicrobial humoral immune response mediated by antimicrobial peptide FBgn0030926
GO:1900424
IEA
PLAZA Integrative Orthologyregulation of defense response to bacterium FBgn0039102
GO:0009966
IEA
PLAZA Integrative Orthologyregulation of signal transduction FBgn0030051
GO:0045934
IEA
PLAZA Integrative Orthologynegative regulation of nucleobase-containing compound metabolic process ENSG00000187045
GO:0009967
IEA
PLAZA Integrative Orthologypositive regulation of signal transduction FBgn0030051
GO:0040009
IEA
PLAZA Integrative Orthologyregulation of growth rate ENSG00000137648
GO:0021700
IEA
PLAZA Integrative Orthologydevelopmental maturation FBgn0000533
GO:0048646
IEA
PLAZA Integrative Orthologyanatomical structure formation involved in morphogenesis FBgn0000533
GO:0055067
IEA
PLAZA Integrative Orthologymonovalent inorganic cation homeostasis ENSG00000160183
GO:0050729
IEA
PLAZA Integrative Orthologypositive regulation of inflammatory response ENSG00000131187
GO:0055065
IEA
PLAZA Integrative Orthologymetal ion homeostasis ENSG00000187045
GO:0061041
IEA
PLAZA Integrative Orthologyregulation of wound healing ENSG00000131187
GO:0019748
IEA
PLAZA Integrative Orthologysecondary metabolic process FBgn0037515
GO:0061045
IEA
PLAZA Integrative Orthologynegative regulation of wound healing ENSG00000131187
GO:0032963
IEA
PLAZA Integrative Orthologycollagen metabolic process ENSG00000187045
GO:0050830
IEA
PLAZA Integrative Orthologydefense response to Gram-positive bacterium FBgn0030051
GO:0050832
IEA
PLAZA Integrative Orthologydefense response to fungus FBgn0030051
GO:0033013
IEA
PLAZA Integrative Orthologytetrapyrrole metabolic process ENSG00000162438
GO:0002759
IEA
PLAZA Integrative Orthologyregulation of antimicrobial humoral response FBgn0030926
GO:0044281
IEA
PLAZA Integrative Orthologysmall molecule metabolic process ENSG00000142789
GO:0009953
IEA
PLAZA Integrative Orthologydorsal/ventral pattern formation FBgn0000533
GO:0002760
IEA
PLAZA Integrative Orthologypositive regulation of antimicrobial humoral response FBgn0030926
GO:0009950
IEA
PLAZA Integrative Orthologydorsal/ventral axis specification FBgn0000533
GO:0048878
IEA
PLAZA Integrative Orthologychemical homeostasis ENSG00000187045
GO:0080134
IEA
PLAZA Integrative Orthologyregulation of response to stress ENSG00000131187
GO:0051806
IEA
PLAZA Integrative Orthologyentry into cell of other organism involved in symbiotic interaction ENSG00000184012
GO:0045924
IEA
PLAZA Integrative Orthologyregulation of female receptivity FBgn0037036
GO:0008063
IEA
PLAZA Integrative OrthologyToll signaling pathway FBgn0000533
GO:0045926
IEA
PLAZA Integrative Orthologynegative regulation of growth ENSG00000137648
GO:0016540
IEA
PLAZA Integrative Orthologyprotein autoprocessing ENSG00000131187
GO:0035966
IEA
PLAZA Integrative Orthologyresponse to topologically incorrect protein ENSG00000131187
GO:0045088
IEA
PLAZA Integrative Orthologyregulation of innate immune response FBgn0037515
GO:0006629
IEA
PLAZA Integrative Orthologylipid metabolic process ENSG00000142789
GO:0045087
IEA
PLAZA Integrative Orthologyinnate immune response ENSG00000131187
GO:0072553
IEA
PLAZA Integrative Orthologyterminal button organization FBgn0029827
GO:0002702
IEA
PLAZA Integrative Orthologypositive regulation of production of molecular mediator of immune response FBgn0030926
GO:0048477
IEA
PLAZA Integrative Orthologyoogenesis FBgn0000533
GO:0045089
IEA
PLAZA Integrative Orthologypositive regulation of innate immune response FBgn0037515
GO:0048599
IEA
PLAZA Integrative Orthologyoocyte development FBgn0000533
GO:0002700
IEA
PLAZA Integrative Orthologyregulation of production of molecular mediator of immune response FBgn0030926
GO:0022412
IEA
PLAZA Integrative Orthologycellular process involved in reproduction in multicellular organism FBgn0000533
GO:0006873
IEA
PLAZA Integrative Orthologycellular ion homeostasis ENSG00000160183
GO:0003002
IEA
PLAZA Integrative Orthologyregionalization FBgn0000533
GO:0006875
IEA
PLAZA Integrative Orthologycellular metal ion homeostasis ENSG00000160183
GO:0045752
IEA
PLAZA Integrative Orthologypositive regulation of Toll signaling pathway FBgn0030051
GO:0048468
IEA
PLAZA Integrative Orthologycell development FBgn0000533
GO:0043455
IEA
PLAZA Integrative Orthologyregulation of secondary metabolic process FBgn0037515
GO:0048469
IEA
PLAZA Integrative Orthologycell maturation FBgn0000533
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process ENSG00000100312
GO:0007281
IEA
PLAZA Integrative Orthologygerm cell development FBgn0000533
GO:0050776
IEA
PLAZA Integrative Orthologyregulation of immune response FBgn0037515
GO:0034645
IEA
PLAZA Integrative Orthologycellular macromolecule biosynthetic process ENSG00000187045
GO:0050778
IEA
PLAZA Integrative Orthologypositive regulation of immune response FBgn0037515
GO:0070268
IEA
PLAZA Integrative Orthologycornification ENSG00000142615
GO:0032101
IEA
PLAZA Integrative Orthologyregulation of response to external stimulus ENSG00000131187
GO:0010558
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule biosynthetic process ENSG00000187045
GO:0002816
IEA
PLAZA Integrative Orthologyregulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria FBgn0039102
GO:0033554
IEA
PLAZA Integrative Orthologycellular response to stress FBgn0039629
GO:0032103
IEA
PLAZA Integrative Orthologypositive regulation of response to external stimulus ENSG00000131187
GO:0002815
IEA
PLAZA Integrative Orthologybiosynthetic process of antibacterial peptides active against Gram-positive bacteria FBgn0039102
GO:0032102
IEA
PLAZA Integrative Orthologynegative regulation of response to external stimulus ENSG00000131187
GO:0051186
IEA
PLAZA Integrative Orthologycofactor metabolic process ENSG00000162438
GO:0048585
IEA
PLAZA Integrative Orthologynegative regulation of response to stimulus ENSG00000131187
GO:0002813
IEA
PLAZA Integrative Orthologyregulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria FBgn0039102
GO:0002812
IEA
PLAZA Integrative Orthologybiosynthetic process of antibacterial peptides active against Gram-negative bacteria FBgn0039102
GO:0050890
IEA
PLAZA Integrative Orthologycognition ENSG00000087128
GO:0002810
IEA
PLAZA Integrative Orthologyregulation of antifungal peptide biosynthetic process FBgn0030926
GO:0097264
IEA
PLAZA Integrative Orthologyself proteolysis ENSG00000187045
GO:0048583
IEA
PLAZA Integrative Orthologyregulation of response to stimulus ENSG00000131187
GO:0048584
IEA
PLAZA Integrative Orthologypositive regulation of response to stimulus ENSG00000131187
GO:1903507
IEA
PLAZA Integrative Orthologynegative regulation of nucleic acid-templated transcription ENSG00000187045
GO:1903506
IEA
PLAZA Integrative Orthologyregulation of nucleic acid-templated transcription ENSG00000187045
GO:1901566
IEA
PLAZA Integrative Orthologyorganonitrogen compound biosynthetic process FBgn0030926
GO:0007276
IEA
PLAZA Integrative Orthologygamete generation FBgn0000533
GO:0006066
IEA
PLAZA Integrative Orthologyalcohol metabolic process ENSG00000142789
GO:1902652
IEA
PLAZA Integrative Orthologysecondary alcohol metabolic process ENSG00000142789
GO:0043207
IEA
PLAZA Integrative Orthologyresponse to external biotic stimulus FBgn0030051
GO:0046718
IEA
PLAZA Integrative Orthologyviral entry into host cell ENSG00000184012
GO:0019953
IEA
PLAZA Integrative Orthologysexual reproduction ENSG00000100312
GO:0007618
IEA
PLAZA Integrative Orthologymating FBgn0037036
GO:0042592
IEA
PLAZA Integrative Orthologyhomeostatic process ENSG00000187045
GO:0009913
IEA
PLAZA Integrative Orthologyepidermal cell differentiation ENSG00000142615
GO:0006767
IEA
PLAZA Integrative Orthologywater-soluble vitamin metabolic process ENSG00000162438
GO:0007617
IEA
PLAZA Integrative Orthologymating behavior FBgn0037036
GO:0030855
IEA
PLAZA Integrative Orthologyepithelial cell differentiation ENSG00000142615
GO:0007621
IEA
PLAZA Integrative Orthologynegative regulation of female receptivity FBgn0037036
GO:0007620
IEA
PLAZA Integrative Orthologycopulation FBgn0037036
GO:0090303
IEA
PLAZA Integrative Orthologypositive regulation of wound healing ENSG00000131187
GO:0044409
IEA
PLAZA Integrative Orthologyentry into host ENSG00000184012
GO:0071219
IEA
PLAZA Integrative Orthologycellular response to molecule of bacterial origin FBgn0030926
GO:0050878
IEA
PLAZA Integrative Orthologyregulation of body fluid levels ENSG00000131187
GO:0071216
IEA
PLAZA Integrative Orthologycellular response to biotic stimulus FBgn0030926
GO:0006518
IEA
PLAZA Integrative Orthologypeptide metabolic process FBgn0030926
GO:0002833
IEA
PLAZA Integrative Orthologypositive regulation of response to biotic stimulus FBgn0030926
GO:0002831
IEA
PLAZA Integrative Orthologyregulation of response to biotic stimulus FBgn0030926
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction FBgn0000533
GO:0007610
IEA
PLAZA Integrative Orthologybehavior FBgn0037036
GO:0045967
IEA
PLAZA Integrative Orthologynegative regulation of growth rate ENSG00000137648
GO:0006766
IEA
PLAZA Integrative Orthologyvitamin metabolic process ENSG00000162438
GO:0009235
IEA
PLAZA Integrative Orthologycobalamin metabolic process ENSG00000162438
GO:0006883
IEA
PLAZA Integrative Orthologycellular sodium ion homeostasis ENSG00000160183
GO:0051172
IEA
PLAZA Integrative Orthologynegative regulation of nitrogen compound metabolic process ENSG00000187045
GO:0030195
IEA
PLAZA Integrative Orthologynegative regulation of blood coagulation ENSG00000131187
GO:0030193
IEA
PLAZA Integrative Orthologyregulation of blood coagulation ENSG00000131187
GO:0030194
IEA
PLAZA Integrative Orthologypositive regulation of blood coagulation ENSG00000131187
GO:0007292
IEA
PLAZA Integrative Orthologyfemale gamete generation FBgn0000533
GO:0035007
IEA
PLAZA Integrative Orthologyregulation of melanization defense response FBgn0037515
GO:0031324
IEA
PLAZA Integrative Orthologynegative regulation of cellular metabolic process ENSG00000187045
GO:0035006
IEA
PLAZA Integrative Orthologymelanization defense response FBgn0037515
GO:0010646
IEA
PLAZA Integrative Orthologyregulation of cell communication FBgn0030051
GO:0035008
IEA
PLAZA Integrative Orthologypositive regulation of melanization defense response FBgn0037515
GO:0010647
IEA
PLAZA Integrative Orthologypositive regulation of cell communication FBgn0030051
GO:0031328
IEA
PLAZA Integrative Orthologypositive regulation of cellular biosynthetic process FBgn0030926
GO:0031327
IEA
PLAZA Integrative Orthologynegative regulation of cellular biosynthetic process ENSG00000187045
GO:0002225
IEA
PLAZA Integrative Orthologypositive regulation of antimicrobial peptide production FBgn0030926
GO:0007369
IEA
PLAZA Integrative Orthologygastrulation FBgn0000533
GO:0006950
IEA
PLAZA Integrative Orthologyresponse to stress ENSG00000131187
GO:0002353
IEA
PLAZA Integrative Orthologyplasma kallikrein-kinin cascade ENSG00000131187
GO:0006952
IEA
PLAZA Integrative Orthologydefense response ENSG00000131187
GO:1900048
IEA
PLAZA Integrative Orthologypositive regulation of hemostasis ENSG00000131187
GO:1900046
IEA
PLAZA Integrative Orthologyregulation of hemostasis ENSG00000131187
GO:0045434
IEA
PLAZA Integrative Orthologynegative regulation of female receptivity, post-mating FBgn0037036
GO:1900047
IEA
PLAZA Integrative Orthologynegative regulation of hemostasis ENSG00000131187
GO:0022617
IEA
PLAZA Integrative Orthologyextracellular matrix disassembly ENSG00000167751
GO:0051788
IEA
PLAZA Integrative Orthologyresponse to misfolded protein ENSG00000131187
GO:0030003
IEA
PLAZA Integrative Orthologycellular cation homeostasis ENSG00000160183
GO:0030004
IEA
PLAZA Integrative Orthologycellular monovalent inorganic cation homeostasis ENSG00000160183
GO:0002699
IEA
PLAZA Integrative Orthologypositive regulation of immune effector process FBgn0030926
GO:0002697
IEA
PLAZA Integrative Orthologyregulation of immune effector process FBgn0030926
GO:0007599
IEA
PLAZA Integrative Orthologyhemostasis ENSG00000131187
GO:0007596
IEA
PLAZA Integrative Orthologyblood coagulation ENSG00000131187
GO:0008202
IEA
PLAZA Integrative Orthologysteroid metabolic process ENSG00000142789
GO:0008203
IEA
PLAZA Integrative Orthologycholesterol metabolic process ENSG00000142789
GO:0007597
IEA
PLAZA Integrative Orthologyblood coagulation, intrinsic pathway ENSG00000131187
GO:0009890
IEA
PLAZA Integrative Orthologynegative regulation of biosynthetic process ENSG00000187045
GO:0009891
IEA
PLAZA Integrative Orthologypositive regulation of biosynthetic process FBgn0030926
GO:0009892
IEA
PLAZA Integrative Orthologynegative regulation of metabolic process ENSG00000187045
GO:1900150
IEA
PLAZA Integrative Orthologyregulation of defense response to fungus FBgn0030926
GO:0034976
IEA
PLAZA Integrative Orthologyresponse to endoplasmic reticulum stress FBgn0039629
GO:0002808
IEA
PLAZA Integrative Orthologyregulation of antibacterial peptide biosynthetic process FBgn0039102
GO:0031347
IEA
PLAZA Integrative Orthologyregulation of defense response ENSG00000131187
GO:0002807
IEA
PLAZA Integrative Orthologypositive regulation of antimicrobial peptide biosynthetic process FBgn0030926
GO:0097659
IEA
PLAZA Integrative Orthologynucleic acid-templated transcription ENSG00000187045
GO:0002805
IEA
PLAZA Integrative Orthologyregulation of antimicrobial peptide biosynthetic process FBgn0030926
GO:0002804
IEA
PLAZA Integrative Orthologypositive regulation of antifungal peptide production FBgn0030926
GO:0002803
IEA
PLAZA Integrative Orthologypositive regulation of antibacterial peptide production FBgn0039102
GO:0002922
IEA
PLAZA Integrative Orthologypositive regulation of humoral immune response FBgn0030926
GO:0023051
IEA
PLAZA Integrative Orthologyregulation of signaling FBgn0030051
GO:0002920
IEA
PLAZA Integrative Orthologyregulation of humoral immune response FBgn0030926
GO:0023056
IEA
PLAZA Integrative Orthologypositive regulation of signaling FBgn0030051
GO:0006965
IEA
PLAZA Integrative Orthologypositive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria FBgn0039102
GO:0031349
IEA
PLAZA Integrative Orthologypositive regulation of defense response ENSG00000131187
GO:0006967
IEA
PLAZA Integrative Orthologypositive regulation of antifungal peptide biosynthetic process FBgn0030926
GO:0065009
IEA
PLAZA Integrative Orthologyregulation of molecular function ENSG00000100312
GO:0002376
IEA
PLAZA Integrative Orthologyimmune system process ENSG00000131187
GO:0002254
IEA
PLAZA Integrative Orthologykinin cascade ENSG00000131187
GO:0002252
IEA
PLAZA Integrative Orthologyimmune effector process FBgn0030926
GO:0007389
IEA
PLAZA Integrative Orthologypattern specification process FBgn0000533
GO:0009566
IEA
PLAZA Integrative Orthologyfertilization ENSG00000100312
GO:0008592
IEA
PLAZA Integrative Orthologyregulation of Toll signaling pathway FBgn0030051
GO:0030260
IEA
PLAZA Integrative Orthologyentry into host cell ENSG00000184012
GO:2000112
IEA
PLAZA Integrative Orthologyregulation of cellular macromolecule biosynthetic process ENSG00000187045
GO:2000113
IEA
PLAZA Integrative Orthologynegative regulation of cellular macromolecule biosynthetic process ENSG00000187045
GO:0006959
IEA
PLAZA Integrative Orthologyhumoral immune response FBgn0039798
GO:0001703
IEA
PLAZA Integrative Orthologygastrulation with mouth forming first FBgn0000533
GO:0050790
IEA
PLAZA Integrative Orthologyregulation of catalytic activity ENSG00000100312
GO:0042381
IEA
PLAZA Integrative Orthologyhemolymph coagulation FBgn0039798
GO:0045892
IEA
PLAZA Integrative Orthologynegative regulation of transcription, DNA-templated ENSG00000187045
GO:0006955
IEA
PLAZA Integrative Orthologyimmune response ENSG00000131187
GO:0002237
IEA
PLAZA Integrative Orthologyresponse to molecule of bacterial origin FBgn0030926
GO:0006954
IEA
PLAZA Integrative Orthologyinflammatory response ENSG00000131187
GO:1902679
IEA
PLAZA Integrative Orthologynegative regulation of RNA biosynthetic process ENSG00000187045
GO:0006964
IEA
PLAZA Integrative Orthologypositive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria FBgn0039102
GO:0043588
IEA
PLAZA Integrative Orthologyskin development ENSG00000142615
GO:0006963
IEA
PLAZA Integrative Orthologypositive regulation of antibacterial peptide biosynthetic process FBgn0039102
GO:0009798
IEA
PLAZA Integrative Orthologyaxis specification FBgn0000533
GO:0007370
IEA
PLAZA Integrative Orthologyventral furrow formation FBgn0000533

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0070008
IEA
Genome Projectserine-type exopeptidase activity
GO:0015269
ISS
Genome Projectcalcium-activated potassium channel activity
GO:0015269
ISS
Gene Ontologycalcium-activated potassium channel activity
GO:0008236
IDA
Genome Projectserine-type peptidase activity
GO:0008236
IDA
Gene Ontologyserine-type peptidase activity5
GO:0008233
IDA
Genome Projectpeptidase activity
GO:0008233
IDA
Gene Ontologypeptidase activity2 3
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 5
GO:0004252
IDA
TAS
Genome Projectserine-type endopeptidase activity
GO:0004252
IDA
TAS
Gene Ontologyserine-type endopeptidase activity3
GO:0019899
IEA
PLAZA Integrative Orthologyenzyme binding ENSG00000100312
GO:0004298
IEA
PLAZA Integrative Orthologythreonine-type endopeptidase activity ENSG00000206549
GO:0098772
IEA
PLAZA Integrative Orthologymolecular function regulator ENSG00000160183
GO:0016247
IEA
PLAZA Integrative Orthologychannel regulator activity ENSG00000160183
GO:0036094
IEA
PLAZA Integrative Orthologysmall molecule binding ENSG00000100312
GO:0005537
IEA
PLAZA Integrative Orthologymannose binding ENSG00000100312
GO:0017080
IEA
PLAZA Integrative Orthologysodium channel regulator activity ENSG00000160183
GO:0002020
IEA
PLAZA Integrative Orthologyprotease binding ENSG00000100312
GO:0070003
IEA
PLAZA Integrative Orthologythreonine-type peptidase activity ENSG00000206549
GO:0004222
IEA
PLAZA Integrative Orthologymetalloendopeptidase activity ENSG00000187045
GO:0048029
IEA
PLAZA Integrative Orthologymonosaccharide binding ENSG00000100312
GO:0051787
IEA
PLAZA Integrative Orthologymisfolded protein binding ENSG00000131187
GO:0030246
IEA
PLAZA Integrative Orthologycarbohydrate binding ENSG00000100312
GO:0008237
IEA
PLAZA Integrative Orthologymetallopeptidase activity ENSG00000187045

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0031965
IDA
Genome Projectnuclear membrane
GO:0031965
IDA
Gene Ontologynuclear membrane1
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0070062
Gene Ontologyextracellular exosome7
GO:0043025
ISS
Genome Projectneuronal cell body
GO:0043025
ISS
Gene Ontologyneuronal cell body
GO:0016324
IEA
Genome Projectapical plasma membrane
GO:0016021
IDA
Genome Projectintegral component of membrane
GO:0016021
IDA
Gene Ontologyintegral component of membrane2
GO:0009986
IDA
Genome Projectcell surface
GO:0009986
IDA
Gene Ontologycell surface3 4
GO:0005911
ISS
Genome Projectcell-cell junction
GO:0005911
ISS
Gene Ontologycell-cell junction
GO:0005887
IDA
Genome Projectintegral component of plasma membrane
GO:0005887
IDA
Gene Ontologyintegral component of plasma membrane8
GO:0005886
IDA
TAS
Genome Projectplasma membrane
GO:0005886
IDA
TAS
Gene Ontologyplasma membrane4
GO:0005789
IDA
Genome Projectendoplasmic reticulum membrane
GO:0005789
IDA
Gene Ontologyendoplasmic reticulum membrane9
GO:0031410
IEA
PLAZA Integrative Orthologycytoplasmic vesicle ENSG00000100312
GO:0032991
IEA
PLAZA Integrative Orthologyprotein-containing complex ENSG00000100312
GO:0043159
IEA
PLAZA Integrative Orthologyacrosomal matrix ENSG00000100312
GO:0005829
IEA
PLAZA Integrative Orthologycytosol ENSG00000142615
GO:0099503
IEA
PLAZA Integrative Orthologysecretory vesicle ENSG00000100312
GO:0097223
IEA
PLAZA Integrative Orthologysperm part ENSG00000100312
GO:0001669
IEA
PLAZA Integrative Orthologyacrosomal vesicle ENSG00000100312
GO:0097708
IEA
PLAZA Integrative Orthologyintracellular vesicle ENSG00000100312
GO:0098595
IEA
PLAZA Integrative Orthologyperivitelline space FBgn0000533
GO:0005773
IEA
PLAZA Integrative Orthologyvacuole ENSG00000100312
GO:0036457
IEA
PLAZA Integrative Orthologykeratohyalin granule ENSG00000142615
GO:0030141
IEA
PLAZA Integrative Orthologysecretory granule ENSG00000100312
GO:0044437
IEA
PLAZA Integrative Orthologyvacuolar part ENSG00000100312
GO:0044433
IEA
PLAZA Integrative Orthologycytoplasmic vesicle part ENSG00000100312

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001254Serine proteases, trypsin domain
IPR001314Peptidase S1A, chymotrypsin family
IPR009003Peptidase S1, PA clan
IPR015352Hepsin, SRCR domain
IPR017448SRCR-like domain
IPR018114Serine proteases, trypsin family, histidine active site
IPR033116Serine proteases, trypsin family, serine active site

No MapMan annotations defined for this gene.
KeggID Description
K08665HPN; hepsin
No chloroplast target sequence found.