Gene: ENSG00000105373 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000105373
Transcript Identifier
ENST00000246802
Gene Type
Coding gene
Location
19 : 47745560-47757005 : positive

Family Information

Homologous gene family
HOM02SEM025594
(3 genes in 3 species)
specific family

Descriptions

gene_descr
glioma tumor suppressor candidate region gene 2

Identifiers

Type Value
pidENSP00000246802
HGNC4333
UniprotQ9NZM5
RefSeq_mRNANM_015710.4
EMBLAF182076
EMBLAF296124
EMBLAL122063
EMBLAL359335
EMBLAL359336
EMBLBC004229
EMBLBC006311
EMBLBC010095

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1903715
IMP
Genome Projectregulation of aerobic respiration
GO:1903715
IMP
Gene Ontologyregulation of aerobic respiration1
GO:1901797
IEA
Genome Projectnegative regulation of signal transduction by p53 class mediator
GO:1901796
IMP
Genome Projectregulation of signal transduction by p53 class mediator
GO:1901796
IMP
Gene Ontologyregulation of signal transduction by p53 class mediator1 2 3 4
GO:0050821
IMP
Genome Projectprotein stabilization
GO:0050821
IMP
Gene Ontologyprotein stabilization5
GO:0032507
IEA
Genome Projectmaintenance of protein location in cell
GO:0032436
IEA
Genome Projectpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032436
IMP
Gene Ontologypositive regulation of proteasomal ubiquitin-dependent protein catabolic process6 7
GO:0008150
ND
Genome Projectbiological_process
GO:0001932
IMP
Genome Projectregulation of protein phosphorylation
GO:0001932
IMP
Gene Ontologyregulation of protein phosphorylation5
GO:0000027
IMP
Genome Projectribosomal large subunit assembly
GO:0000027
IMP
Gene Ontologyribosomal large subunit assembly3
GO:1990173
IMP
Gene Ontologyprotein localization to nucleoplasm6 7
GO:1903006
IMP
Gene Ontologypositive regulation of protein K63-linked deubiquitination8
GO:1901837
IMP
Gene Ontologynegative regulation of transcription of nucleolar large rRNA by RNA polymerase I9
GO:0071456
IMP
Gene Ontologycellular response to hypoxia2
GO:0051898
IMP
Gene Ontologynegative regulation of protein kinase B signaling9
GO:0051726
IMP
Gene Ontologyregulation of cell cycle10
GO:0042981
IMP
Gene Ontologyregulation of apoptotic process10
GO:0039535
IMP
Gene Ontologyregulation of RIG-I signaling pathway8
GO:0031333
IMP
Gene Ontologynegative regulation of protein complex assembly11
GO:0032435
IMP
Gene Ontologynegative regulation of proteasomal ubiquitin-dependent protein catabolic process2
GO:0014067
IMP
Gene Ontologynegative regulation of phosphatidylinositol 3-kinase signaling12
GO:0007095
IMP
Gene Ontologymitotic G2 DNA damage checkpoint13
GO:0006974
IMP
Gene Ontologycellular response to DNA damage stimulus4
GO:0006281
IMP
Gene OntologyDNA repair13
GO:0000122
IMP
Gene Ontologynegative regulation of transcription by RNA polymerase II11
GO:0010971
IEA
PLAZA Integrative Orthologypositive regulation of G2/M transition of mitotic cell cycle AT2G40430
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process FBgn0030061
GO:0030154
IEA
PLAZA Integrative Orthologycell differentiation FBgn0030061
GO:0048731
IEA
PLAZA Integrative Orthologysystem development FBgn0030061
GO:0051781
IEA
PLAZA Integrative Orthologypositive regulation of cell division AT2G40430
GO:0051302
IEA
PLAZA Integrative Orthologyregulation of cell division AT2G40430
GO:0051301
IEA
PLAZA Integrative Orthologycell division AT2G40430
GO:0048869
IEA
PLAZA Integrative Orthologycellular developmental process FBgn0030061
GO:1901857
IEA
PLAZA Integrative Orthologypositive regulation of cellular respiration WBGene00012692
GO:0045931
IEA
PLAZA Integrative Orthologypositive regulation of mitotic cell cycle AT2G40430
GO:1901989
IEA
PLAZA Integrative Orthologypositive regulation of cell cycle phase transition AT2G40430
GO:0022008
IEA
PLAZA Integrative Orthologyneurogenesis FBgn0030061
GO:0045787
IEA
PLAZA Integrative Orthologypositive regulation of cell cycle AT2G40430
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development FBgn0030061
GO:0007399
IEA
PLAZA Integrative Orthologynervous system development FBgn0030061
GO:0090068
IEA
PLAZA Integrative Orthologypositive regulation of cell cycle process AT2G40430
GO:1901992
IEA
PLAZA Integrative Orthologypositive regulation of mitotic cell cycle phase transition AT2G40430
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development FBgn0030061
GO:1902751
IEA
PLAZA Integrative Orthologypositive regulation of cell cycle G2/M phase transition AT2G40430

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008097
IDA
Genome Project5S rRNA binding
GO:0008097
IDA
Gene Ontology5S rRNA binding3
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 4 5 7 8 9 10 11 14
GO:0003723
IDA
Genome ProjectRNA binding
GO:0003723
Gene OntologyRNA binding15 16
GO:0042802
IDA
Gene Ontologyidentical protein binding17
GO:0002039
IPI
Gene Ontologyp53 binding2

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0043231
IDA
Genome Projectintracellular membrane-bounded organelle
GO:0043231
IDA
Gene Ontologyintracellular membrane-bounded organelle
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005730
IDA
Genome Projectnucleolus
GO:0005730
IDA
Gene Ontologynucleolus2 4 7 11 14 18
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005654
IDA
Gene Ontologynucleoplasm2 7 18
GO:0005622
NAS
Genome Projectintracellular
GO:0005622
NAS
Gene Ontologyintracellular19
GO:0033553
IDA
Gene OntologyrDNA heterochromatin9
GO:0005829
IDA
Gene Ontologycytosol18
GO:0001650
IDA
Gene Ontologyfibrillar center9

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR011687Ribosome biogenesis protein Nop53/GLTSCR2

No MapMan annotations defined for this gene.
KeggID Description
K14840NOP53, GLTSCR2; nucleolar protein 53
No chloroplast target sequence found.