Gene: ENSG00000104313 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000104313
Transcript Identifier
ENST00000340726
Gene Type
Coding gene
Location
8 : 71199340-71354905 : negative

Family Information

Homologous gene family
HOM02SEM007568
(12 genes in 6 species)
specific family
Orthologous gene family
ORTHO02SEM006719
(12 genes in 6 species)
specific family

Descriptions

gene_descr
EYA transcriptional coactivator and phosphatase 1

Identifiers

Type Value
pidENSP00000342626
HGNC3519
UniprotQ99502
UniprotA0A024R813
RefSeq_mRNANM_000503.5
EMBLCH471068

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:2001240
IBA
Genome Projectnegative regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:0090103
IEA
Genome Projectcochlea morphogenesis
GO:0072513
IEA
Genome Projectpositive regulation of secondary heart field cardioblast proliferation
GO:0071600
IEA
Genome Projectotic vesicle morphogenesis
GO:0060487
IEA
Genome Projectlung epithelial cell differentiation
GO:0060037
IEA
Genome Projectpharyngeal system development
GO:0050679
IEA
Genome Projectpositive regulation of epithelial cell proliferation
GO:0048752
IEA
Genome Projectsemicircular canal morphogenesis
GO:0048704
IEA
Genome Projectembryonic skeletal system morphogenesis
GO:0048665
IEA
Genome Projectneuron fate specification
GO:0045944
IEA
Genome Projectpositive regulation of transcription by RNA polymerase II
GO:0045747
IEA
Genome Projectpositive regulation of Notch signaling pathway
GO:0045739
IMP
Genome Projectpositive regulation of DNA repair
GO:0045739
IMP
Gene Ontologypositive regulation of DNA repair1
GO:0045664
IEA
Genome Projectregulation of neuron differentiation
GO:0042474
IEA
Genome Projectmiddle ear morphogenesis
GO:0042473
IEA
Genome Projectouter ear morphogenesis
GO:0035909
IEA
Genome Projectaorta morphogenesis
GO:0035335
IEA
Genome Projectpeptidyl-tyrosine dephosphorylation
GO:0035088
IEA
Genome Projectestablishment or maintenance of apical/basal cell polarity
GO:0034613
IEA
Genome Projectcellular protein localization
GO:0030154
IBA
Genome Projectcell differentiation
GO:0016925
ISS
Genome Projectprotein sumoylation
GO:0016925
ISS
Gene Ontologyprotein sumoylation
GO:0016576
IDA
Genome Projecthistone dephosphorylation
GO:0016576
IDA
Gene Ontologyhistone dephosphorylation1
GO:0014706
IEA
Genome Projectstriated muscle tissue development
GO:0010212
IDA
Genome Projectresponse to ionizing radiation
GO:0010212
IDA
Gene Ontologyresponse to ionizing radiation1
GO:0009653
TAS
Genome Projectanatomical structure morphogenesis
GO:0009653
TAS
Gene Ontologyanatomical structure morphogenesis2
GO:0007605
TAS
Genome Projectsensory perception of sound
GO:0007605
TAS
Gene Ontologysensory perception of sound2
GO:0007501
IEA
Genome Projectmesodermal cell fate specification
GO:0007389
IEA
Genome Projectpattern specification process
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006302
IMP
Genome Projectdouble-strand break repair
GO:0006302
IMP
Gene Ontologydouble-strand break repair1
GO:0003151
IEA
Genome Projectoutflow tract morphogenesis
GO:0001658
IEA
Genome Projectbranching involved in ureteric bud morphogenesis
GO:0001656
IEA
Genome Projectmetanephros development
GO:0000132
IEA
Genome Projectestablishment of mitotic spindle orientation
GO:0043065
IEA
PLAZA Integrative Orthologypositive regulation of apoptotic process WBGene00001377
GO:0045087
IEA
PLAZA Integrative Orthologyinnate immune response FBgn0000320
GO:0048477
IEA
PLAZA Integrative Orthologyoogenesis FBgn0000320
GO:0019098
IEA
PLAZA Integrative Orthologyreproductive behavior WBGene00001377
GO:0008406
IEA
PLAZA Integrative Orthologygonad development FBgn0000320
GO:0048592
IEA
PLAZA Integrative Orthologyeye morphogenesis FBgn0000320
GO:0048870
IEA
PLAZA Integrative Orthologycell motility FBgn0000320
GO:0048232
IEA
PLAZA Integrative Orthologymale gamete generation FBgn0000320
GO:0022412
IEA
PLAZA Integrative Orthologycellular process involved in reproduction in multicellular organism FBgn0000320
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction WBGene00001377
GO:0048749
IEA
PLAZA Integrative Orthologycompound eye development FBgn0000320
GO:0007601
IEA
PLAZA Integrative Orthologyvisual perception ENSG00000158161
GO:0007444
IEA
PLAZA Integrative Orthologyimaginal disc development FBgn0000320
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process WBGene00001377
GO:0007283
IEA
PLAZA Integrative Orthologyspermatogenesis FBgn0000320
GO:0007560
IEA
PLAZA Integrative Orthologyimaginal disc morphogenesis FBgn0000320
GO:0007280
IEA
PLAZA Integrative Orthologypole cell migration FBgn0000320
GO:0044703
IEA
PLAZA Integrative Orthologymulti-organism reproductive process FBgn0000320
GO:0007281
IEA
PLAZA Integrative Orthologygerm cell development FBgn0000320
GO:0035214
IEA
PLAZA Integrative Orthologyeye-antennal disc development FBgn0000320
GO:0050931
IEA
PLAZA Integrative Orthologypigment cell differentiation FBgn0000320
GO:0045596
IEA
PLAZA Integrative Orthologynegative regulation of cell differentiation FBgn0000320
GO:0032989
IEA
PLAZA Integrative Orthologycellular component morphogenesis FBgn0000320
GO:0009605
IEA
PLAZA Integrative Orthologyresponse to external stimulus FBgn0000320
GO:0007548
IEA
PLAZA Integrative Orthologysex differentiation FBgn0000320
GO:0032504
IEA
PLAZA Integrative Orthologymulticellular organism reproduction WBGene00001377
GO:0048066
IEA
PLAZA Integrative Orthologydevelopmental pigmentation FBgn0000320
GO:0006979
IEA
PLAZA Integrative Orthologyresponse to oxidative stress WBGene00001377
GO:0007435
IEA
PLAZA Integrative Orthologysalivary gland morphogenesis FBgn0000320
GO:0048858
IEA
PLAZA Integrative Orthologycell projection morphogenesis FBgn0000320
GO:0048732
IEA
PLAZA Integrative Orthologygland development FBgn0000320
GO:0007431
IEA
PLAZA Integrative Orthologysalivary gland development FBgn0000320
GO:0007552
IEA
PLAZA Integrative Orthologymetamorphosis FBgn0000320
GO:0007276
IEA
PLAZA Integrative Orthologygamete generation FBgn0000320
GO:0055034
IEA
PLAZA Integrative OrthologyBolwig's organ development FBgn0000320
GO:0032990
IEA
PLAZA Integrative Orthologycell part morphogenesis FBgn0000320
GO:0019953
IEA
PLAZA Integrative Orthologysexual reproduction FBgn0000320
GO:0006928
IEA
PLAZA Integrative Orthologymovement of cell or subcellular component FBgn0000320
GO:0072499
IEA
PLAZA Integrative Orthologyphotoreceptor cell axon guidance FBgn0000320
GO:0001754
IEA
PLAZA Integrative Orthologyeye photoreceptor cell differentiation FBgn0000320
GO:0001751
IEA
PLAZA Integrative Orthologycompound eye photoreceptor cell differentiation FBgn0000320
GO:1902884
IEA
PLAZA Integrative Orthologypositive regulation of response to oxidative stress WBGene00001377
GO:0046546
IEA
PLAZA Integrative Orthologydevelopment of primary male sexual characteristics FBgn0000320
GO:0048569
IEA
PLAZA Integrative Orthologypost-embryonic animal organ development FBgn0000320
GO:0042221
IEA
PLAZA Integrative Orthologyresponse to chemical FBgn0000320
GO:0009886
IEA
PLAZA Integrative Orthologypost-embryonic animal morphogenesis FBgn0000320
GO:0042462
IEA
PLAZA Integrative Orthologyeye photoreceptor cell development FBgn0000320
GO:1902882
IEA
PLAZA Integrative Orthologyregulation of response to oxidative stress WBGene00001377
GO:0048608
IEA
PLAZA Integrative Orthologyreproductive structure development FBgn0000320
GO:0048609
IEA
PLAZA Integrative Orthologymulticellular organismal reproductive process WBGene00001377
GO:0010454
IEA
PLAZA Integrative Orthologynegative regulation of cell fate commitment FBgn0000320
GO:0010453
IEA
PLAZA Integrative Orthologyregulation of cell fate commitment FBgn0000320
GO:0071697
IEA
PLAZA Integrative Orthologyectodermal placode morphogenesis FBgn0000320
GO:0018991
IEA
PLAZA Integrative Orthologyoviposition WBGene00001377
GO:0046661
IEA
PLAZA Integrative Orthologymale sex differentiation FBgn0000320
GO:0042461
IEA
PLAZA Integrative Orthologyphotoreceptor cell development FBgn0000320
GO:0048563
IEA
PLAZA Integrative Orthologypost-embryonic animal organ morphogenesis FBgn0000320
GO:0001746
IEA
PLAZA Integrative OrthologyBolwig's organ morphogenesis FBgn0000320
GO:0071696
IEA
PLAZA Integrative Orthologyectodermal placode development FBgn0000320
GO:0001745
IEA
PLAZA Integrative Orthologycompound eye morphogenesis FBgn0000320
GO:0001744
IEA
PLAZA Integrative Orthologyoptic lobe placode formation FBgn0000320
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction FBgn0000320
GO:0007610
IEA
PLAZA Integrative Orthologybehavior WBGene00001377
GO:0002165
IEA
PLAZA Integrative Orthologyinstar larval or pupal development FBgn0000320
GO:0002164
IEA
PLAZA Integrative Orthologylarval development WBGene00001377
GO:0007455
IEA
PLAZA Integrative Orthologyeye-antennal disc morphogenesis FBgn0000320
GO:0009996
IEA
PLAZA Integrative Orthologynegative regulation of cell fate specification FBgn0000320
GO:0042330
IEA
PLAZA Integrative Orthologytaxis FBgn0000320
GO:0120039
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection morphogenesis FBgn0000320
GO:0120036
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection organization FBgn0000320
GO:0007292
IEA
PLAZA Integrative Orthologyfemale gamete generation FBgn0000320
GO:0046530
IEA
PLAZA Integrative Orthologyphotoreceptor cell differentiation FBgn0000320
GO:0042051
IEA
PLAZA Integrative Orthologycompound eye photoreceptor development FBgn0000320
GO:0051674
IEA
PLAZA Integrative Orthologylocalization of cell FBgn0000320
GO:0001654
IEA
PLAZA Integrative Orthologyeye development FBgn0000320
GO:0007525
IEA
PLAZA Integrative Orthologysomatic muscle development FBgn0000320
GO:0006952
IEA
PLAZA Integrative Orthologydefense response FBgn0000320
GO:0048666
IEA
PLAZA Integrative Orthologyneuron development FBgn0000320
GO:1902742
IEA
PLAZA Integrative Orthologyapoptotic process involved in development WBGene00001377
GO:0048667
IEA
PLAZA Integrative Orthologycell morphogenesis involved in neuron differentiation FBgn0000320
GO:0022612
IEA
PLAZA Integrative Orthologygland morphogenesis FBgn0000320
GO:0031175
IEA
PLAZA Integrative Orthologyneuron projection development FBgn0000320
GO:0009266
IEA
PLAZA Integrative Orthologyresponse to temperature stimulus WBGene00001377
GO:0048707
IEA
PLAZA Integrative Orthologyinstar larval or pupal morphogenesis FBgn0000320
GO:0016477
IEA
PLAZA Integrative Orthologycell migration FBgn0000320
GO:0051704
IEA
PLAZA Integrative Orthologymulti-organism process FBgn0000320
GO:0034605
IEA
PLAZA Integrative Orthologycellular response to heat WBGene00001377
GO:0009408
IEA
PLAZA Integrative Orthologyresponse to heat WBGene00001377
GO:0006935
IEA
PLAZA Integrative Orthologychemotaxis FBgn0000320
GO:0060788
IEA
PLAZA Integrative Orthologyectodermal placode formation FBgn0000320
GO:0009416
IEA
PLAZA Integrative Orthologyresponse to light stimulus FBgn0000320
GO:0002066
IEA
PLAZA Integrative Orthologycolumnar/cuboidal epithelial cell development FBgn0000320
GO:0042675
IEA
PLAZA Integrative Orthologycompound eye cone cell differentiation FBgn0000320
GO:0002065
IEA
PLAZA Integrative Orthologycolumnar/cuboidal epithelial cell differentiation FBgn0000320
GO:0002064
IEA
PLAZA Integrative Orthologyepithelial cell development FBgn0000320
GO:0048812
IEA
PLAZA Integrative Orthologyneuron projection morphogenesis FBgn0000320
GO:1900036
IEA
PLAZA Integrative Orthologypositive regulation of cellular response to heat WBGene00001377
GO:1900034
IEA
PLAZA Integrative Orthologyregulation of cellular response to heat WBGene00001377
GO:0040011
IEA
PLAZA Integrative Orthologylocomotion WBGene00001377
GO:0010942
IEA
PLAZA Integrative Orthologypositive regulation of cell death WBGene00001377
GO:0150063
IEA
PLAZA Integrative Orthologyvisual system development FBgn0000320
GO:0007417
IEA
PLAZA Integrative Orthologycentral nervous system development FBgn0000320
GO:0007419
IEA
PLAZA Integrative Orthologyventral cord development FBgn0000320
GO:1904747
IEA
PLAZA Integrative Orthologypositive regulation of apoptotic process involved in development WBGene00001377
GO:0002376
IEA
PLAZA Integrative Orthologyimmune system process FBgn0000320
GO:1904748
IEA
PLAZA Integrative Orthologyregulation of apoptotic process involved in development WBGene00001377
GO:0008354
IEA
PLAZA Integrative Orthologygerm cell migration FBgn0000320
GO:0045137
IEA
PLAZA Integrative Orthologydevelopment of primary sexual characteristics FBgn0000320
GO:0000902
IEA
PLAZA Integrative Orthologycell morphogenesis FBgn0000320
GO:0035272
IEA
PLAZA Integrative Orthologyexocrine system development FBgn0000320
GO:0000904
IEA
PLAZA Integrative Orthologycell morphogenesis involved in differentiation FBgn0000320
GO:0061564
IEA
PLAZA Integrative Orthologyaxon development FBgn0000320
GO:0050953
IEA
PLAZA Integrative Orthologysensory perception of light stimulus ENSG00000158161
GO:0061061
IEA
PLAZA Integrative Orthologymuscle structure development FBgn0000320
GO:0007409
IEA
PLAZA Integrative Orthologyaxonogenesis FBgn0000320
GO:0030707
IEA
PLAZA Integrative Orthologyovarian follicle cell development FBgn0000320
GO:0043473
IEA
PLAZA Integrative Orthologypigmentation FBgn0000320
GO:0070285
IEA
PLAZA Integrative Orthologypigment cell development FBgn0000320
GO:0002119
IEA
PLAZA Integrative Orthologynematode larval development WBGene00001377
GO:0006955
IEA
PLAZA Integrative Orthologyimmune response FBgn0000320
GO:0007526
IEA
PLAZA Integrative Orthologylarval somatic muscle development FBgn0000320
GO:0048880
IEA
PLAZA Integrative Orthologysensory system development FBgn0000320
GO:0097485
IEA
PLAZA Integrative Orthologyneuron projection guidance FBgn0000320
GO:0061458
IEA
PLAZA Integrative Orthologyreproductive system development FBgn0000320
GO:0051094
IEA
PLAZA Integrative Orthologypositive regulation of developmental process WBGene00001377
GO:0051093
IEA
PLAZA Integrative Orthologynegative regulation of developmental process FBgn0000320
GO:0007411
IEA
PLAZA Integrative Orthologyaxon guidance FBgn0000320
GO:0043068
IEA
PLAZA Integrative Orthologypositive regulation of programmed cell death WBGene00001377
GO:0030030
IEA
PLAZA Integrative Orthologycell projection organization FBgn0000320
GO:0009791
IEA
PLAZA Integrative Orthologypost-embryonic development WBGene00001377
GO:0008584
IEA
PLAZA Integrative Orthologymale gonad development FBgn0000320
GO:0042659
IEA
PLAZA Integrative Orthologyregulation of cell fate specification FBgn0000320

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding3
GO:0004725
IDA
Genome Projectprotein tyrosine phosphatase activity
GO:0004725
IDA
Gene Ontologyprotein tyrosine phosphatase activity1
GO:0003723
IEA
Genome ProjectRNA binding
GO:0008134
IEA
PLAZA Integrative Orthologytranscription factor binding FBgn0000320
GO:0003713
IEA
PLAZA Integrative Orthologytranscription coactivator activity FBgn0000320
GO:0003712
IEA
PLAZA Integrative Orthologytranscription coregulator activity FBgn0000320
GO:0000287
IEA
PLAZA Integrative Orthologymagnesium ion binding ENSG00000064655
GO:0140110
IEA
PLAZA Integrative Orthologytranscription regulator activity FBgn0000320
GO:0030946
IEA
PLAZA Integrative Orthologyprotein tyrosine phosphatase activity, metal-dependent AT2G35320

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0032993
IEA
Genome Projectprotein-DNA complex
GO:0016604
IDA
Genome Projectnuclear body
GO:0016604
IDA
Gene Ontologynuclear body
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005737
IDA
Gene Ontologycytoplasm4
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005654
IDA
TAS
Gene Ontologynucleoplasm
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus1 4
GO:0044430
IEA
PLAZA Integrative Orthologycytoskeletal part ENSG00000158161
GO:0005815
IEA
PLAZA Integrative Orthologymicrotubule organizing center ENSG00000158161
GO:0005813
IEA
PLAZA Integrative Orthologycentrosome ENSG00000158161
GO:0005829
IEA
PLAZA Integrative Orthologycytosol ENSG00000064655
GO:0015630
IEA
PLAZA Integrative Orthologymicrotubule cytoskeleton ENSG00000158161
GO:0005856
IEA
PLAZA Integrative Orthologycytoskeleton ENSG00000158161
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part ENSG00000064655
GO:0043232
IEA
PLAZA Integrative Orthologyintracellular non-membrane-bounded organelle ENSG00000158161
GO:0043228
IEA
PLAZA Integrative Orthologynon-membrane-bounded organelle ENSG00000158161

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR006545EYA domain
IPR028471Eyes absent homologue 1
IPR028472Eyes absent family

No MapMan annotations defined for this gene.
KeggID Description
K15616EYA1; eyes absent homolog 1
No chloroplast target sequence found.