Gene: ENSG00000103035 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000103035
Transcript Identifier
ENST00000219313
Gene Type
Coding gene
Location
16 : 74296915-74305733 : positive

Family Information

Homologous gene family
HOM02SEM002399
(29 genes in 25 species)
specific family
Orthologous gene family
ORTHO02SEM002512
(29 genes in 25 species)
specific family

Descriptions

gene_descr
proteasome (prosome, macropain) 26S subunit, non- ATPase, 7

Identifiers

Type Value
pidENSP00000219313
HGNC9565
UniprotP51665
RefSeq_mRNANM_002811.4
EMBLBC000338
EMBLBC012606
EMBLCH471166
EMBLD50063

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0090263
TAS
Genome Projectpositive regulation of canonical Wnt signaling pathway
GO:0090090
TAS
Genome Projectnegative regulation of canonical Wnt signaling pathway
GO:0061418
TAS
Genome Projectregulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0060071
TAS
Genome ProjectWnt signaling pathway, planar cell polarity pathway
GO:0055085
TAS
Genome Projecttransmembrane transport
GO:0050852
TAS
Genome ProjectT cell receptor signaling pathway
GO:0043687
TAS
Genome Projectpost-translational protein modification
GO:0043687
TAS
Gene Ontologypost-translational protein modification
GO:0043488
TAS
Genome Projectregulation of mRNA stability
GO:0043312
TAS
Genome Projectneutrophil degranulation
GO:0043312
TAS
Gene Ontologyneutrophil degranulation
GO:0043161
IBA
TAS
Genome Projectproteasome-mediated ubiquitin-dependent protein catabolic process
GO:0038095
TAS
Genome ProjectFc-epsilon receptor signaling pathway
GO:0038061
TAS
Genome ProjectNIK/NF-kappaB signaling
GO:0033209
TAS
Genome Projecttumor necrosis factor-mediated signaling pathway
GO:0031146
TAS
Genome ProjectSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031145
TAS
Genome Projectanaphase-promoting complex-dependent catabolic process
GO:0016579
TAS
Genome Projectprotein deubiquitination
GO:0016579
TAS
Gene Ontologyprotein deubiquitination
GO:0010972
TAS
Genome Projectnegative regulation of G2/M transition of mitotic cell cycle
GO:0006521
TAS
Genome Projectregulation of cellular amino acid metabolic process
GO:0002479
TAS
Genome Projectantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002223
TAS
Genome Projectstimulatory C-type lectin receptor signaling pathway
GO:0000209
TAS
Genome Projectprotein polyubiquitination
GO:0000165
TAS
Genome ProjectMAPK cascade
GO:0010965
IEA
PLAZA Integrative Orthologyregulation of mitotic sister chromatid separation SPCC1682.10
GO:0051276
IEA
PLAZA Integrative Orthologychromosome organization SPCC1682.10
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction AT3G11270
GO:0048827
IEA
PLAZA Integrative Orthologyphyllome development AT5G05780
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization SPCC1682.10
GO:0044784
IEA
PLAZA Integrative Orthologymetaphase/anaphase transition of cell cycle SPCC1682.10
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process AT3G11270
GO:1901970
IEA
PLAZA Integrative Orthologypositive regulation of mitotic sister chromatid separation SPCC1682.10
GO:0062033
IEA
PLAZA Integrative Orthologypositive regulation of mitotic sister chromatid segregation SPCC1682.10
GO:1902101
IEA
PLAZA Integrative Orthologypositive regulation of metaphase/anaphase transition of cell cycle SPCC1682.10
GO:0007088
IEA
PLAZA Integrative Orthologyregulation of mitotic nuclear division SPCC1682.10
GO:0051304
IEA
PLAZA Integrative Orthologychromosome separation SPCC1682.10
GO:0051306
IEA
PLAZA Integrative Orthologymitotic sister chromatid separation SPCC1682.10
GO:0140014
IEA
PLAZA Integrative Orthologymitotic nuclear division SPCC1682.10
GO:0010638
IEA
PLAZA Integrative Orthologypositive regulation of organelle organization SPCC1682.10
GO:0000280
IEA
PLAZA Integrative Orthologynuclear division SPCC1682.10
GO:0099402
IEA
PLAZA Integrative Orthologyplant organ development AT5G05780
GO:0051783
IEA
PLAZA Integrative Orthologyregulation of nuclear division SPCC1682.10
GO:0051984
IEA
PLAZA Integrative Orthologypositive regulation of chromosome segregation SPCC1682.10
GO:0051785
IEA
PLAZA Integrative Orthologypositive regulation of nuclear division SPCC1682.10
GO:0051983
IEA
PLAZA Integrative Orthologyregulation of chromosome segregation SPCC1682.10
GO:0045787
IEA
PLAZA Integrative Orthologypositive regulation of cell cycle SPCC1682.10
GO:0033043
IEA
PLAZA Integrative Orthologyregulation of organelle organization SPCC1682.10
GO:1902099
IEA
PLAZA Integrative Orthologyregulation of metaphase/anaphase transition of cell cycle SPCC1682.10
GO:0033044
IEA
PLAZA Integrative Orthologyregulation of chromosome organization SPCC1682.10
GO:1905392
IEA
PLAZA Integrative Orthologyplant organ morphogenesis AT5G05780
GO:0033045
IEA
PLAZA Integrative Orthologyregulation of sister chromatid segregation SPCC1682.10
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis SPCC1682.10
GO:0033047
IEA
PLAZA Integrative Orthologyregulation of mitotic sister chromatid segregation SPCC1682.10
GO:0000070
IEA
PLAZA Integrative Orthologymitotic sister chromatid segregation SPCC1682.10
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization SPCC1682.10
GO:0051130
IEA
PLAZA Integrative Orthologypositive regulation of cellular component organization SPCC1682.10
GO:0045931
IEA
PLAZA Integrative Orthologypositive regulation of mitotic cell cycle SPCC1682.10
GO:0009965
IEA
PLAZA Integrative Orthologyleaf morphogenesis AT5G05780
GO:1901992
IEA
PLAZA Integrative Orthologypositive regulation of mitotic cell cycle phase transition SPCC1682.10
GO:0090068
IEA
PLAZA Integrative Orthologypositive regulation of cell cycle process SPCC1682.10
GO:0048608
IEA
PLAZA Integrative Orthologyreproductive structure development AT3G11270
GO:0010154
IEA
PLAZA Integrative Orthologyfruit development AT3G11270
GO:0007091
IEA
PLAZA Integrative Orthologymetaphase/anaphase transition of mitotic cell cycle SPCC1682.10
GO:0051128
IEA
PLAZA Integrative Orthologyregulation of cellular component organization SPCC1682.10
GO:0098813
IEA
PLAZA Integrative Orthologynuclear chromosome segregation SPCC1682.10
GO:0010016
IEA
PLAZA Integrative Orthologyshoot system morphogenesis AT5G05780
GO:0048366
IEA
PLAZA Integrative Orthologyleaf development AT5G05780
GO:0048367
IEA
PLAZA Integrative Orthologyshoot system development AT5G05780
GO:0048285
IEA
PLAZA Integrative Orthologyorganelle fission SPCC1682.10
GO:1905818
IEA
PLAZA Integrative Orthologyregulation of chromosome separation SPCC1682.10
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction AT3G11270
GO:0061458
IEA
PLAZA Integrative Orthologyreproductive system development AT3G11270
GO:1901989
IEA
PLAZA Integrative Orthologypositive regulation of cell cycle phase transition SPCC1682.10
GO:0048316
IEA
PLAZA Integrative Orthologyseed development AT3G11270
GO:0045840
IEA
PLAZA Integrative Orthologypositive regulation of mitotic nuclear division SPCC1682.10
GO:0007059
IEA
PLAZA Integrative Orthologychromosome segregation SPCC1682.10
GO:0009791
IEA
PLAZA Integrative Orthologypost-embryonic development AT3G11270
GO:0045842
IEA
PLAZA Integrative Orthologypositive regulation of mitotic metaphase/anaphase transition SPCC1682.10
GO:0009793
IEA
PLAZA Integrative Orthologyembryo development ending in seed dormancy AT3G11270
GO:1905820
IEA
PLAZA Integrative Orthologypositive regulation of chromosome separation SPCC1682.10
GO:0030071
IEA
PLAZA Integrative Orthologyregulation of mitotic metaphase/anaphase transition SPCC1682.10
GO:2001252
IEA
PLAZA Integrative Orthologypositive regulation of chromosome organization SPCC1682.10
GO:0000819
IEA
PLAZA Integrative Orthologysister chromatid segregation SPCC1682.10
GO:0009790
IEA
PLAZA Integrative Orthologyembryo development AT3G11270

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0042803
IDA
Genome Projectprotein homodimerization activity
GO:0042803
IDA
Gene Ontologyprotein homodimerization activity1
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding2 3 4 5

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1904813
TAS
Genome Projectficolin-1-rich granule lumen
GO:1904813
TAS
Gene Ontologyficolin-1-rich granule lumen
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0070062
Gene Ontologyextracellular exosome6
GO:0034774
TAS
Genome Projectsecretory granule lumen
GO:0034774
TAS
Gene Ontologysecretory granule lumen
GO:0016020
IDA
Genome Projectmembrane
GO:0016020
Gene Ontologymembrane7
GO:0005838
IEA
Genome Projectproteasome regulatory particle
GO:0005829
TAS
Genome Projectcytosol
GO:0005829
TAS
Gene Ontologycytosol
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005654
IDA
TAS
Gene Ontologynucleoplasm
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
Gene Ontologynucleus8
GO:0005576
TAS
Genome Projectextracellular region
GO:0005576
TAS
Gene Ontologyextracellular region
GO:0000502
IDA
Genome Projectproteasome complex
GO:0000502
IDA
Gene Ontologyproteasome complex9
GO:0034515
IEA
PLAZA Integrative Orthologyproteasome storage granule YOR261C
GO:0005819
IEA
PLAZA Integrative Orthologyspindle SPCC1682.10
GO:0044430
IEA
PLAZA Integrative Orthologycytoskeletal part SPCC1682.10
GO:0005856
IEA
PLAZA Integrative Orthologycytoskeleton SPCC1682.10
GO:0051233
IEA
PLAZA Integrative Orthologyspindle midzone SPCC1682.10
GO:0031967
IEA
PLAZA Integrative Orthologyorganelle envelope SPCC1682.10
GO:0031975
IEA
PLAZA Integrative Orthologyenvelope SPCC1682.10
GO:0072686
IEA
PLAZA Integrative Orthologymitotic spindle SPCC1682.10
GO:1990023
IEA
PLAZA Integrative Orthologymitotic spindle midzone SPCC1682.10
GO:0005635
IEA
PLAZA Integrative Orthologynuclear envelope SPCC1682.10
GO:0044445
IEA
PLAZA Integrative Orthologycytosolic part YOR261C
GO:0043232
IEA
PLAZA Integrative Orthologyintracellular non-membrane-bounded organelle SPCC1682.10
GO:0031597
IEA
PLAZA Integrative Orthologycytosolic proteasome complex YOR261C
GO:0043228
IEA
PLAZA Integrative Orthologynon-membrane-bounded organelle SPCC1682.10
GO:0008541
IEA
PLAZA Integrative Orthologyproteasome regulatory particle, lid subcomplex SPCC1682.10
GO:0015630
IEA
PLAZA Integrative Orthologymicrotubule cytoskeleton SPCC1682.10

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000555JAB1/MPN/MOV34 metalloenzyme domain
IPR024969Rpn11/EIF3F, C-terminal
IPR03385826S Proteasome non-ATPase regulatory subunit 7/8

No MapMan annotations defined for this gene.
KeggID Description
K03038PSMD7, RPN8; 26S proteasome regulatory subunit N8
No chloroplast target sequence found.