Gene: ENSG00000101843 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000101843
Transcript Identifier
ENST00000217958
Gene Type
Coding gene
Location
X : 108084974-108091520 : negative

Family Information

Homologous gene family
HOM02SEM000258
(115 genes in 16 species)
specific family

Descriptions

gene_descr
proteasome (prosome, macropain) 26S subunit, non- ATPase, 10

Identifiers

Type Value
pidENSP00000217958
HGNC9555
UniprotO75832
RefSeq_mRNANM_002814.3
EMBLCHEMBL2331054
EMBLAB009619
EMBLAK295996
EMBLAL031177
EMBLAY057056
EMBLBC011960
EMBLBT019689
EMBLD83197

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0090263
TAS
Genome Projectpositive regulation of canonical Wnt signaling pathway
GO:0090201
IMP
Genome Projectnegative regulation of release of cytochrome c from mitochondria
GO:0090201
IMP
Gene Ontologynegative regulation of release of cytochrome c from mitochondria1
GO:0090090
TAS
Genome Projectnegative regulation of canonical Wnt signaling pathway
GO:0070682
IMP
Genome Projectproteasome regulatory particle assembly
GO:0070682
IMP
Gene Ontologyproteasome regulatory particle assembly2
GO:0061418
TAS
Genome Projectregulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0060071
TAS
Genome ProjectWnt signaling pathway, planar cell polarity pathway
GO:0055085
TAS
Genome Projecttransmembrane transport
GO:0050852
TAS
Genome ProjectT cell receptor signaling pathway
GO:0045737
IDA
Genome Projectpositive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045737
IDA
Gene Ontologypositive regulation of cyclin-dependent protein serine/threonine kinase activity3
GO:0043687
TAS
Genome Projectpost-translational protein modification
GO:0043687
TAS
Gene Ontologypost-translational protein modification
GO:0043518
IDA
Genome Projectnegative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0043518
IDA
Gene Ontologynegative regulation of DNA damage response, signal transduction by p53 class mediator4
GO:0043488
TAS
Genome Projectregulation of mRNA stability
GO:0043409
IMP
Genome Projectnegative regulation of MAPK cascade
GO:0043409
IMP
Gene Ontologynegative regulation of MAPK cascade1
GO:0043161
TAS
Genome Projectproteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043066
IDA, IMP
Genome Projectnegative regulation of apoptotic process
GO:0043066
IDA, IMP
Gene Ontologynegative regulation of apoptotic process1 4
GO:0038095
TAS
Genome ProjectFc-epsilon receptor signaling pathway
GO:0038061
TAS
Genome ProjectNIK/NF-kappaB signaling
GO:0033209
TAS
Genome Projecttumor necrosis factor-mediated signaling pathway
GO:0032436
IDA
TAS
Genome Projectpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032436
IDA
TAS
Gene Ontologypositive regulation of proteasomal ubiquitin-dependent protein catabolic process4 5
GO:0032088
IDA
Genome Projectnegative regulation of NF-kappaB transcription factor activity
GO:0032088
IDA
Gene Ontologynegative regulation of NF-kappaB transcription factor activity6
GO:0031398
IMP
Genome Projectpositive regulation of protein ubiquitination
GO:0031398
IMP
Gene Ontologypositive regulation of protein ubiquitination4
GO:0031146
TAS
Genome ProjectSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031145
TAS
Genome Projectanaphase-promoting complex-dependent catabolic process
GO:0030307
IDA
Genome Projectpositive regulation of cell growth
GO:0030307
IDA
Gene Ontologypositive regulation of cell growth5
GO:0016579
TAS
Genome Projectprotein deubiquitination
GO:0016579
TAS
Gene Ontologyprotein deubiquitination
GO:0010972
TAS
Genome Projectnegative regulation of G2/M transition of mitotic cell cycle
GO:0007253
IDA
Genome Projectcytoplasmic sequestering of NF-kappaB
GO:0007253
IDA
Gene Ontologycytoplasmic sequestering of NF-kappaB6
GO:0006915
IEA
Genome Projectapoptotic process
GO:0006521
TAS
Genome Projectregulation of cellular amino acid metabolic process
GO:0002479
TAS
Genome Projectantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002223
TAS
Genome Projectstimulatory C-type lectin receptor signaling pathway
GO:0000209
TAS
Genome Projectprotein polyubiquitination
GO:0000165
TAS
Genome ProjectMAPK cascade
GO:0000122
IDA
Genome Projectnegative regulation of transcription by RNA polymerase II
GO:0000122
IDA
Gene Ontologynegative regulation of transcription by RNA polymerase II4

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008134
IPI
Genome Projecttranscription factor binding
GO:0008134
IPI
Gene Ontologytranscription factor binding6
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding2 3 4 5 7 8 9 10 11 12 13

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008540
IDA
Genome Projectproteasome regulatory particle, base subcomplex
GO:0008540
IDA
Gene Ontologyproteasome regulatory particle, base subcomplex2
GO:0045111
IDA
Genome Projectintermediate filament cytoskeleton
GO:0045111
IDA
Gene Ontologyintermediate filament cytoskeleton
GO:0005838
TAS
Genome Projectproteasome regulatory particle
GO:0005838
TAS
Gene Ontologyproteasome regulatory particle14
GO:0005829
IDA
TAS
Genome Projectcytosol
GO:0005829
IDA
TAS
Gene Ontologycytosol
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005737
IDA
Gene Ontologycytoplasm6
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005654
TAS
Gene Ontologynucleoplasm
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus6
GO:0000502
IDA
Genome Projectproteasome complex
GO:0000502
IDA
Gene Ontologyproteasome complex15

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002110Ankyrin repeat
IPR020683Ankyrin repeat-containing domain

No MapMan annotations defined for this gene.
KeggID Description
K06694PSMD10; 26S proteasome non-ATPase regulatory subunit 10
No chloroplast target sequence found.