Gene: ENSG00000095637 (Homo sapiens)

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Gene Identifier
ENSG00000095637
Transcript Identifier
ENST00000607232
Gene Type
Coding gene
Location
10 : 95315059-95441135 : negative

Family Information

Homologous gene family
HOM02SEM004883
(17 genes in 3 species)
specific family
Orthologous gene family
ORTHO02SEM008663
(9 genes in 3 species)
specific family

Descriptions

gene_descr
sorbin and SH3 domain containing 1

Identifiers

Type Value
pidENSP00000475901
HGNC14565
UniprotQ9BX66

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0048041
ISS
Genome Projectfocal adhesion assembly
GO:0048041
ISS
Gene Ontologyfocal adhesion assembly
GO:0046889
ISS
Genome Projectpositive regulation of lipid biosynthetic process
GO:0046889
ISS
Gene Ontologypositive regulation of lipid biosynthetic process1
GO:0046326
ISS
Genome Projectpositive regulation of glucose import
GO:0046326
ISS
Gene Ontologypositive regulation of glucose import1
GO:0045725
ISS
Genome Projectpositive regulation of glycogen biosynthetic process
GO:0045725
ISS
Gene Ontologypositive regulation of glycogen biosynthetic process1
GO:0043149
ISS
Genome Projectstress fiber assembly
GO:0043149
ISS
Gene Ontologystress fiber assembly
GO:0032869
ISS
Genome Projectcellular response to insulin stimulus
GO:0032869
ISS
Gene Ontologycellular response to insulin stimulus1
GO:0009967
IEA
Genome Projectpositive regulation of signal transduction
GO:0008286
ISS
Genome Projectinsulin receptor signaling pathway
GO:0008286
ISS
Gene Ontologyinsulin receptor signaling pathway
GO:0007160
TAS
Genome Projectcell-matrix adhesion
GO:0007160
TAS
Gene Ontologycell-matrix adhesion2
GO:0006936
TAS
Genome Projectmuscle contraction
GO:0006936
TAS
Gene Ontologymuscle contraction
GO:1903078
ISS
Gene Ontologypositive regulation of protein localization to plasma membrane
GO:0016203
IEA
PLAZA Integrative Orthologymuscle attachment FBgn0033504
GO:0032970
IEA
PLAZA Integrative Orthologyregulation of actin filament-based process ENSG00000120896
GO:0032233
IEA
PLAZA Integrative Orthologypositive regulation of actin filament bundle assembly ENSG00000120896
GO:0051493
IEA
PLAZA Integrative Orthologyregulation of cytoskeleton organization ENSG00000120896
GO:0051130
IEA
PLAZA Integrative Orthologypositive regulation of cellular component organization ENSG00000120896
GO:0051496
IEA
PLAZA Integrative Orthologypositive regulation of stress fiber assembly ENSG00000120896
GO:0048731
IEA
PLAZA Integrative Orthologysystem development FBgn0033504
GO:0051495
IEA
PLAZA Integrative Orthologypositive regulation of cytoskeleton organization ENSG00000120896
GO:0032956
IEA
PLAZA Integrative Orthologyregulation of actin cytoskeleton organization ENSG00000120896
GO:0007517
IEA
PLAZA Integrative Orthologymuscle organ development FBgn0033504
GO:0007600
IEA
PLAZA Integrative Orthologysensory perception FBgn0033504
GO:0110020
IEA
PLAZA Integrative Orthologyregulation of actomyosin structure organization ENSG00000120896
GO:0060538
IEA
PLAZA Integrative Orthologyskeletal muscle organ development FBgn0033504
GO:0051128
IEA
PLAZA Integrative Orthologyregulation of cellular component organization ENSG00000120896
GO:0050954
IEA
PLAZA Integrative Orthologysensory perception of mechanical stimulus FBgn0033504
GO:0050877
IEA
PLAZA Integrative Orthologynervous system process FBgn0033504
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process FBgn0033504
GO:0061061
IEA
PLAZA Integrative Orthologymuscle structure development FBgn0033504
GO:0010638
IEA
PLAZA Integrative Orthologypositive regulation of organelle organization ENSG00000120896
GO:0044089
IEA
PLAZA Integrative Orthologypositive regulation of cellular component biogenesis ENSG00000120896
GO:0044087
IEA
PLAZA Integrative Orthologyregulation of cellular component biogenesis ENSG00000120896
GO:1902903
IEA
PLAZA Integrative Orthologyregulation of supramolecular fiber organization ENSG00000120896
GO:0007605
IEA
PLAZA Integrative Orthologysensory perception of sound FBgn0033504
GO:1902905
IEA
PLAZA Integrative Orthologypositive regulation of supramolecular fiber organization ENSG00000120896
GO:0110053
IEA
PLAZA Integrative Orthologyregulation of actin filament organization ENSG00000120896
GO:0048513
IEA
PLAZA Integrative Orthologyanimal organ development FBgn0033504
GO:0051492
IEA
PLAZA Integrative Orthologyregulation of stress fiber assembly ENSG00000120896
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development FBgn0033504
GO:0033043
IEA
PLAZA Integrative Orthologyregulation of organelle organization ENSG00000120896
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development FBgn0033504
GO:0032231
IEA
PLAZA Integrative Orthologyregulation of actin filament bundle assembly ENSG00000120896

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008092
TAS
Genome Projectcytoskeletal protein binding
GO:0008092
TAS
Gene Ontologycytoskeletal protein binding2
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding3 4 5 6 7 8 9
GO:0005158
IDA
Genome Projectinsulin receptor binding
GO:0005158
IDA
Gene Ontologyinsulin receptor binding4
GO:0005070
ISS
IC
Genome ProjectSH3/SH2 adaptor activity
GO:0005070
ISS
IC
Gene OntologySH3/SH2 adaptor activity4 10
GO:0003779
TAS
Genome Projectactin binding
GO:0003779
TAS
Gene Ontologyactin binding2
GO:0097159
IEA
PLAZA Integrative Orthologyorganic cyclic compound binding ENSG00000154556
GO:0008307
IEA
PLAZA Integrative Orthologystructural constituent of muscle ENSG00000154556
GO:0003676
IEA
PLAZA Integrative Orthologynucleic acid binding ENSG00000154556
GO:0005200
IEA
PLAZA Integrative Orthologystructural constituent of cytoskeleton ENSG00000120896
GO:0008093
IEA
PLAZA Integrative Orthologycytoskeletal adaptor activity ENSG00000154556
GO:0017166
IEA
PLAZA Integrative Orthologyvinculin binding ENSG00000120896
GO:0003723
IEA
PLAZA Integrative OrthologyRNA binding ENSG00000154556
GO:0005198
IEA
PLAZA Integrative Orthologystructural molecule activity ENSG00000120896
GO:1901363
IEA
PLAZA Integrative Orthologyheterocyclic compound binding ENSG00000154556

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005899
IDA
Genome Projectinsulin receptor complex
GO:0005899
IDA
Gene Ontologyinsulin receptor complex4
GO:0045121
ISS
Genome Projectmembrane raft
GO:0045121
ISS
Gene Ontologymembrane raft
GO:0016363
IEA
Genome Projectnuclear matrix
GO:0005925
IDA
Genome Projectfocal adhesion
GO:0005925
IDA
Gene Ontologyfocal adhesion
GO:0005924
ISS
Genome Projectcell-substrate adherens junction
GO:0005924
ISS
Gene Ontologycell-substrate adherens junction
GO:0005915
TAS
Genome Projectzonula adherens
GO:0005915
TAS
Gene Ontologyzonula adherens2
GO:0005913
ISS
Genome Projectcell-cell adherens junction
GO:0005913
ISS
Gene Ontologycell-cell adherens junction
GO:0005886
IDA
Genome Projectplasma membrane
GO:0005886
IDA
Gene Ontologyplasma membrane
GO:0005829
ISS
TAS
Genome Projectcytosol
GO:0005829
ISS
TAS
Gene Ontologycytosol10
GO:0005813
IDA
Genome Projectcentrosome
GO:0005813
IDA
Gene Ontologycentrosome
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus3
GO:0001725
ISS
Genome Projectstress fiber
GO:0001725
ISS
Gene Ontologystress fiber
GO:0005654
IEA
PLAZA Integrative Orthologynucleoplasm ENSG00000154556

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001452SH3 domain
IPR003127SoHo domain
IPR028506Sorbin and SH3 domain-containing protein

No MapMan annotations defined for this gene.
KeggID Description
K06086SORBS1, SH3D5, PONSIN, CAP; sorbin and SH3 domain containing 1
No chloroplast target sequence found.