Gene: ENSG00000090432 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000090432
Transcript Identifier
ENST00000264198
Gene Type
Coding gene
Location
1 : 20500690-20508024 : negative

Family Information

Homologous gene family
HOM02SEM035246
(2 genes in 2 species)
specific family

Descriptions

gene_descr
mitochondrial E3 ubiquitin protein ligase 1

Identifiers

Type Value
pidENSP00000264198
HGNC25762
UniprotQ969V5
UniprotA0A024RAA0
RefSeq_mRNANM_024544.2
EMBLAB097015
EMBLAK022937
EMBLAL391357
EMBLAL833889
EMBLBC010101
EMBLBC014010
EMBLCH471134
EMBLEU935008

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1904925
IEA
Genome Projectpositive regulation of autophagy of mitochondrion in response to mitochondrial depolarization
GO:1903861
IEA
Genome Projectpositive regulation of dendrite extension
GO:1901028
IDA
Genome Projectregulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
GO:1901028
IDA
Gene Ontologyregulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway1
GO:0090141
IDA
Genome Projectpositive regulation of mitochondrial fission
GO:0090141
IDA
Gene Ontologypositive regulation of mitochondrial fission2
GO:0071650
IMP
Genome Projectnegative regulation of chemokine (C-C motif) ligand 5 production
GO:0071650
IMP
Gene Ontologynegative regulation of chemokine (C-C motif) ligand 5 production3
GO:0071360
IDA
Genome Projectcellular response to exogenous dsRNA
GO:0071360
IDA
Gene Ontologycellular response to exogenous dsRNA3
GO:0060339
IMP
Genome Projectnegative regulation of type I interferon-mediated signaling pathway
GO:0060339
IMP
Gene Ontologynegative regulation of type I interferon-mediated signaling pathway3
GO:0051898
IDA
Genome Projectnegative regulation of protein kinase B signaling
GO:0051898
IDA
Gene Ontologynegative regulation of protein kinase B signaling4
GO:0051881
IEA
Genome Projectregulation of mitochondrial membrane potential
GO:0051646
IMP
Genome Projectmitochondrion localization
GO:0051646
IMP
Gene Ontologymitochondrion localization5
GO:0050821
IMP
Genome Projectprotein stabilization
GO:0050821
IMP
Gene Ontologyprotein stabilization2
GO:0050689
IMP
Genome Projectnegative regulation of defense response to virus by host
GO:0050689
IMP
Gene Ontologynegative regulation of defense response to virus by host3
GO:0045824
IMP
Genome Projectnegative regulation of innate immune response
GO:0045824
IMP
Gene Ontologynegative regulation of innate immune response3
GO:0043123
IMP
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043123
Gene Ontologypositive regulation of I-kappaB kinase/NF-kappaB signaling6
GO:0033235
IDA
Genome Projectpositive regulation of protein sumoylation
GO:0033235
IDA
Gene Ontologypositive regulation of protein sumoylation2
GO:0031648
IMP
Genome Projectprotein destabilization
GO:0031648
IMP
Gene Ontologyprotein destabilization7
GO:0030308
IDA
Genome Projectnegative regulation of cell growth
GO:0030308
IDA
Gene Ontologynegative regulation of cell growth1
GO:0016925
IEA
Genome Projectprotein sumoylation
GO:0016567
IDA
IEA
Genome Projectprotein ubiquitination
GO:0016567
IDA
Gene Ontologyprotein ubiquitination5
GO:0010821
IMP
Genome Projectregulation of mitochondrion organization
GO:0010821
IMP
Gene Ontologyregulation of mitochondrion organization7
GO:0010637
IDA
Genome Projectnegative regulation of mitochondrial fusion
GO:0010637
IDA
Gene Ontologynegative regulation of mitochondrial fusion2
GO:0007257
IDA
Genome Projectactivation of JUN kinase activity
GO:0007257
IDA
Gene Ontologyactivation of JUN kinase activity1
GO:0006919
IDA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006919
IDA
Gene Ontologyactivation of cysteine-type endopeptidase activity involved in apoptotic process1
GO:0006915
IEA
Genome Projectapoptotic process
GO:0000266
IMP
Genome Projectmitochondrial fission
GO:0000266
IMP
Gene Ontologymitochondrial fission8

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0042802
IPI
Genome Projectidentical protein binding
GO:0042802
IPI
Gene Ontologyidentical protein binding1
GO:0031625
IPI
Genome Projectubiquitin protein ligase binding
GO:0031625
IPI
Gene Ontologyubiquitin protein ligase binding2
GO:0019789
IDA
Genome ProjectSUMO transferase activity
GO:0019789
IDA
Gene OntologySUMO transferase activity2
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 2 3 9 10 11
GO:0004842
IDA
Genome Projectubiquitin-protein transferase activity
GO:0004842
IDA
Gene Ontologyubiquitin-protein transferase activity1 5

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0043025
IMP
Genome Projectneuronal cell body
GO:0043025
IMP
Gene Ontologyneuronal cell body7
GO:0031307
IDA
Genome Projectintegral component of mitochondrial outer membrane
GO:0031307
IDA
Gene Ontologyintegral component of mitochondrial outer membrane5 8
GO:0030424
IMP
Genome Projectaxon
GO:0030424
IMP
Gene Ontologyaxon7
GO:0016020
IDA
Genome Projectmembrane
GO:0016020
Gene Ontologymembrane12
GO:0005777
IDA
Genome Projectperoxisome
GO:0005777
IDA
Gene Ontologyperoxisome8
GO:0005739
IDA, IMP
Genome Projectmitochondrion
GO:0005739
IDA, IMP
Gene Ontologymitochondrion7

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001841Zinc finger, RING-type
IPR022170E3 Ubiquitin ligase, GIDE-type

No MapMan annotations defined for this gene.
KeggID Description
K15688MUL1; E3 ubiquitin-protein ligase MUL1
No chloroplast target sequence found.