Gene: ENSG00000086827 (Homo sapiens)

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Gene Identifier
ENSG00000086827
Transcript Identifier
ENST00000200135
Gene Type
Coding gene
Location
11 : 113733694-113773666 : negative

Family Information

Homologous gene family
HOM02SEM005731
(15 genes in 14 species)
specific family

Descriptions

gene_descr
zw10 kinetochore protein

Identifiers

Type Value
pidENSP00000200135
HGNC13194
UniprotO43264
RefSeq_mRNANM_004724.3

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0051321
TAS
Genome Projectmeiotic cell cycle
GO:0051321
TAS
Gene Ontologymeiotic cell cycle1
GO:0051301
IEA
Genome Projectcell division
GO:0034501
IMP
Genome Projectprotein localization to kinetochore
GO:0034501
IMP
Gene Ontologyprotein localization to kinetochore2
GO:0015031
IEA
Genome Projectprotein transport
GO:0007096
IDA
Genome Projectregulation of exit from mitosis
GO:0007096
IDA
Gene Ontologyregulation of exit from mitosis3
GO:0007094
IBA
Genome Projectmitotic spindle assembly checkpoint
GO:0007093
IDA
Genome Projectmitotic cell cycle checkpoint
GO:0007093
IDA
Gene Ontologymitotic cell cycle checkpoint3
GO:0007080
IMP
Genome Projectmitotic metaphase plate congression
GO:0007080
IMP
Gene Ontologymitotic metaphase plate congression2
GO:0007062
TAS
Genome Projectsister chromatid cohesion
GO:0007030
IMP, IGI
Genome ProjectGolgi organization
GO:0007030
IMP, IGI
Gene OntologyGolgi organization4
GO:0006890
TAS
Genome Projectretrograde vesicle-mediated transport, Golgi to ER
GO:0006890
TAS
Gene Ontologyretrograde vesicle-mediated transport, Golgi to ER
GO:0006888
IMP
Genome ProjectER to Golgi vesicle-mediated transport
GO:0006888
IMP
Gene OntologyER to Golgi vesicle-mediated transport5
GO:0000132
IMP
Genome Projectestablishment of mitotic spindle orientation
GO:0000132
IMP
Gene Ontologyestablishment of mitotic spindle orientation2
GO:0000070
IDA
Genome Projectmitotic sister chromatid segregation
GO:0000070
IDA
Gene Ontologymitotic sister chromatid segregation3
GO:0065003
IDA
Gene Ontologyprotein-containing complex assembly3
GO:0033206
IEA
PLAZA Integrative Orthologymeiotic cytokinesis FBgn0004643
GO:0019953
IEA
PLAZA Integrative Orthologysexual reproduction FBgn0004643
GO:0010324
IEA
PLAZA Integrative Orthologymembrane invagination FBgn0004643
GO:0030154
IEA
PLAZA Integrative Orthologycell differentiation FBgn0004643
GO:0048731
IEA
PLAZA Integrative Orthologysystem development FBgn0004643
GO:0048232
IEA
PLAZA Integrative Orthologymale gamete generation FBgn0004643
GO:0022412
IEA
PLAZA Integrative Orthologycellular process involved in reproduction in multicellular organism FBgn0004643
GO:0048869
IEA
PLAZA Integrative Orthologycellular developmental process FBgn0004643
GO:0007107
IEA
PLAZA Integrative Orthologymembrane addition at site of cytokinesis FBgn0004643
GO:0007140
IEA
PLAZA Integrative Orthologymale meiotic nuclear division FBgn0004643
GO:0007060
IEA
PLAZA Integrative Orthologymale meiosis chromosome segregation FBgn0004643
GO:0048609
IEA
PLAZA Integrative Orthologymulticellular organismal reproductive process FBgn0004643
GO:0061024
IEA
PLAZA Integrative Orthologymembrane organization FBgn0004643
GO:0044703
IEA
PLAZA Integrative Orthologymulti-organism reproductive process FBgn0004643
GO:0061640
IEA
PLAZA Integrative Orthologycytoskeleton-dependent cytokinesis FBgn0004643
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process FBgn0004643
GO:0140013
IEA
PLAZA Integrative Orthologymeiotic nuclear division FBgn0004643
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process FBgn0004643
GO:0051704
IEA
PLAZA Integrative Orthologymulti-organism process FBgn0004643
GO:0045132
IEA
PLAZA Integrative Orthologymeiotic chromosome segregation FBgn0004643
GO:0032527
IEA
PLAZA Integrative Orthologyprotein exit from endoplasmic reticulum AT2G32900
GO:0032504
IEA
PLAZA Integrative Orthologymulticellular organism reproduction FBgn0004643
GO:0099024
IEA
PLAZA Integrative Orthologyplasma membrane invagination FBgn0004643
GO:0032506
IEA
PLAZA Integrative Orthologycytokinetic process FBgn0004643
GO:0036090
IEA
PLAZA Integrative Orthologycleavage furrow ingression FBgn0004643
GO:0006886
IEA
PLAZA Integrative Orthologyintracellular protein transport AT2G32900
GO:0007112
IEA
PLAZA Integrative Orthologymale meiosis cytokinesis FBgn0004643
GO:0007276
IEA
PLAZA Integrative Orthologygamete generation FBgn0004643
GO:0022008
IEA
PLAZA Integrative Orthologyneurogenesis FBgn0004643
GO:0000910
IEA
PLAZA Integrative Orthologycytokinesis FBgn0004643
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development FBgn0004643
GO:0007399
IEA
PLAZA Integrative Orthologynervous system development FBgn0004643
GO:1903046
IEA
PLAZA Integrative Orthologymeiotic cell cycle process FBgn0004643
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development FBgn0004643

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0019237
TAS
Genome Projectcentromeric DNA binding
GO:0019237
TAS
Gene Ontologycentromeric DNA binding6
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding2 3 5 7 8 9 10 11 12 13 14 15
GO:0019899
IEA
PLAZA Integrative Orthologyenzyme binding FBgn0004643
GO:0017016
IEA
PLAZA Integrative OrthologyRas GTPase binding FBgn0004643
GO:0017137
IEA
PLAZA Integrative OrthologyRab GTPase binding FBgn0004643
GO:0031267
IEA
PLAZA Integrative Orthologysmall GTPase binding FBgn0004643
GO:0051020
IEA
PLAZA Integrative OrthologyGTPase binding FBgn0004643

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1990423
IDA
Genome ProjectRZZ complex
GO:1990423
IDA
Gene OntologyRZZ complex14
GO:0070939
IDA
Genome ProjectDsl1/NZR complex
GO:0070939
IDA
Gene OntologyDsl1/NZR complex14
GO:0016020
IDA
Genome Projectmembrane
GO:0016020
Gene Ontologymembrane16
GO:0005829
IDA
TAS
Genome Projectcytosol
GO:0005829
IDA
TAS
Gene Ontologycytosol
GO:0005828
IDA
Genome Projectkinetochore microtubule
GO:0005828
IDA
Gene Ontologykinetochore microtubule3
GO:0005789
IEA
Genome Projectendoplasmic reticulum membrane
GO:0005783
IDA
Genome Projectendoplasmic reticulum
GO:0005783
IDA
Gene Ontologyendoplasmic reticulum5
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus9
GO:0000922
IDA
Genome Projectspindle pole
GO:0000922
IDA
Gene Ontologyspindle pole3
GO:0000777
IEA
Genome Projectcondensed chromosome kinetochore
GO:0000776
IDA
Genome Projectkinetochore
GO:0000776
IDA
Gene Ontologykinetochore2 9 17 18
GO:0051233
IEA
PLAZA Integrative Orthologyspindle midzone FBgn0004643
GO:0098791
IEA
PLAZA Integrative OrthologyGolgi subcompartment FBgn0004643
GO:0036063
IEA
PLAZA Integrative Orthologyacroblast FBgn0004643
GO:0005795
IEA
PLAZA Integrative OrthologyGolgi stack FBgn0004643
GO:0005794
IEA
PLAZA Integrative OrthologyGolgi apparatus FBgn0004643
GO:0044431
IEA
PLAZA Integrative OrthologyGolgi apparatus part FBgn0004643

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR009361RZZ complex, subunit Zw10

No MapMan annotations defined for this gene.
KeggID Description
K11578ZW10, DSL1; protein transport protein DSL1/ZW10
No chloroplast target sequence found.