Gene: ENSG00000080986 (Homo sapiens)

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Gene Identifier
ENSG00000080986
Transcript Identifier
ENST00000261597
Gene Type
Coding gene
Location
18 : 2572986-2616574 : positive

Family Information

Homologous gene family
HOM02SEM003043
(25 genes in 22 species)
specific family
Orthologous gene family
ORTHO02SEM003376
(24 genes in 21 species)
specific family

Descriptions

gene_descr
NDC80 kinetochore complex component

Identifiers

Type Value
pidENSP00000261597
HGNC16909
UniprotO14777
UniprotA8K031
RefSeq_mRNANM_006101.2
EMBLCHEMBL5660
EMBLAF017790
EMBLAK289396
EMBLAK313184
EMBLBC010171
EMBLCH471113

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1905342
IMP
Genome Projectpositive regulation of protein localization to kinetochore
GO:1905342
IMP
Gene Ontologypositive regulation of protein localization to kinetochore1
GO:0090267
IMP
Genome Projectpositive regulation of mitotic cell cycle spindle assembly checkpoint
GO:0090267
IMP
Gene Ontologypositive regulation of mitotic cell cycle spindle assembly checkpoint2
GO:0051383
IMP
Genome Projectkinetochore organization
GO:0051383
IMP
Gene Ontologykinetochore organization1
GO:0051315
IMP
Genome Projectattachment of mitotic spindle microtubules to kinetochore
GO:0051315
IMP
Gene Ontologyattachment of mitotic spindle microtubules to kinetochore2 3
GO:0051310
IMP
Genome Projectmetaphase plate congression
GO:0051310
IMP
Gene Ontologymetaphase plate congression2
GO:0051301
IEA
Genome Projectcell division
GO:0008608
IMP
Genome Projectattachment of spindle microtubules to kinetochore
GO:0008608
IMP
Gene Ontologyattachment of spindle microtubules to kinetochore4
GO:0007062
TAS
Genome Projectsister chromatid cohesion
GO:0007059
IMP
Genome Projectchromosome segregation
GO:0007059
IMP
Gene Ontologychromosome segregation5
GO:0007052
IMP
Genome Projectmitotic spindle organization
GO:0007052
IMP
Gene Ontologymitotic spindle organization5
GO:0000278
TAS
Genome Projectmitotic cell cycle
GO:0000278
TAS
Gene Ontologymitotic cell cycle6
GO:0000132
IMP
Genome Projectestablishment of mitotic spindle orientation
GO:0000132
IMP
Gene Ontologyestablishment of mitotic spindle orientation4
GO:0000070
TAS
Genome Projectmitotic sister chromatid segregation
GO:0000070
TAS
Gene Ontologymitotic sister chromatid segregation6
GO:0071824
IEA
PLAZA Integrative Orthologyprotein-DNA complex subunit organization WBGene00003576
GO:0051316
IEA
PLAZA Integrative Orthologyattachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation SPBC11C11.03
GO:2000145
IEA
PLAZA Integrative Orthologyregulation of cell motility WBGene00003576
GO:0097435
IEA
PLAZA Integrative Orthologysupramolecular fiber organization YIL144W
GO:0008406
IEA
PLAZA Integrative Orthologygonad development WBGene00003576
GO:0051674
IEA
PLAZA Integrative Orthologylocalization of cell WBGene00003576
GO:0048870
IEA
PLAZA Integrative Orthologycell motility WBGene00003576
GO:0007127
IEA
PLAZA Integrative Orthologymeiosis I SPBC11C11.03
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction SPBC11C11.03
GO:0043254
IEA
PLAZA Integrative Orthologyregulation of protein complex assembly WBGene00003576
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process SPBC11C11.03
GO:1901970
IEA
PLAZA Integrative Orthologypositive regulation of mitotic sister chromatid separation WBGene00003576
GO:0062033
IEA
PLAZA Integrative Orthologypositive regulation of mitotic sister chromatid segregation WBGene00003576
GO:1903394
IEA
PLAZA Integrative Orthologyprotein localization to kinetochore involved in kinetochore assembly WBGene00003576
GO:0061982
IEA
PLAZA Integrative Orthologymeiosis I cell cycle process SPBC11C11.03
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process WBGene00003576
GO:0140013
IEA
PLAZA Integrative Orthologymeiotic nuclear division SPBC11C11.03
GO:0031334
IEA
PLAZA Integrative Orthologypositive regulation of protein complex assembly WBGene00003576
GO:0016477
IEA
PLAZA Integrative Orthologycell migration WBGene00003576
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process WBGene00003576
GO:0051305
IEA
PLAZA Integrative Orthologychromosome movement towards spindle pole WBGene00003576
GO:0010638
IEA
PLAZA Integrative Orthologypositive regulation of organelle organization WBGene00003576
GO:0007548
IEA
PLAZA Integrative Orthologysex differentiation WBGene00003576
GO:0051984
IEA
PLAZA Integrative Orthologypositive regulation of chromosome segregation WBGene00003576
GO:0051785
IEA
PLAZA Integrative Orthologypositive regulation of nuclear division WBGene00003576
GO:0051270
IEA
PLAZA Integrative Orthologyregulation of cellular component movement WBGene00003576
GO:0007079
IEA
PLAZA Integrative Orthologymitotic chromosome movement towards spindle pole WBGene00003576
GO:0009653
IEA
PLAZA Integrative Orthologyanatomical structure morphogenesis WBGene00003576
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development WBGene00003576
GO:0090230
IEA
PLAZA Integrative Orthologyregulation of centromere complex assembly WBGene00003576
GO:0035262
IEA
PLAZA Integrative Orthologygonad morphogenesis WBGene00003576
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development WBGene00003576
GO:0040011
IEA
PLAZA Integrative Orthologylocomotion WBGene00003576
GO:0090234
IEA
PLAZA Integrative Orthologyregulation of kinetochore assembly WBGene00003576
GO:0040012
IEA
PLAZA Integrative Orthologyregulation of locomotion WBGene00003576
GO:1905561
IEA
PLAZA Integrative Orthologypositive regulation of kinetochore assembly WBGene00003576
GO:0030334
IEA
PLAZA Integrative Orthologyregulation of cell migration WBGene00003576
GO:0045143
IEA
PLAZA Integrative Orthologyhomologous chromosome segregation SPBC11C11.03
GO:0051130
IEA
PLAZA Integrative Orthologypositive regulation of cellular component organization WBGene00003576
GO:0006928
IEA
PLAZA Integrative Orthologymovement of cell or subcellular component WBGene00003576
GO:0048731
IEA
PLAZA Integrative Orthologysystem development WBGene00003576
GO:0051258
IEA
PLAZA Integrative Orthologyprotein polymerization YIL144W
GO:0031109
IEA
PLAZA Integrative Orthologymicrotubule polymerization or depolymerization YIL144W
GO:0051455
IEA
PLAZA Integrative Orthologyattachment of spindle microtubules to kinetochore involved in homologous chromosome segregation SPBC11C11.03
GO:0009887
IEA
PLAZA Integrative Orthologyanimal organ morphogenesis WBGene00003576
GO:0046785
IEA
PLAZA Integrative Orthologymicrotubule polymerization YIL144W
GO:0051382
IEA
PLAZA Integrative Orthologykinetochore assembly WBGene00003576
GO:0045137
IEA
PLAZA Integrative Orthologydevelopment of primary sexual characteristics WBGene00003576
GO:0007020
IEA
PLAZA Integrative Orthologymicrotubule nucleation YIL144W
GO:0065004
IEA
PLAZA Integrative Orthologyprotein-DNA complex assembly WBGene00003576
GO:0090268
IEA
PLAZA Integrative Orthologyactivation of mitotic cell cycle spindle assembly checkpoint SPBC11C11.03
GO:0065003
IEA
PLAZA Integrative Orthologyprotein-containing complex assembly YIL144W
GO:0048608
IEA
PLAZA Integrative Orthologyreproductive structure development WBGene00003576
GO:0034622
IEA
PLAZA Integrative Orthologycellular protein-containing complex assembly YIL144W
GO:0045132
IEA
PLAZA Integrative Orthologymeiotic chromosome segregation SPBC11C11.03
GO:0044089
IEA
PLAZA Integrative Orthologypositive regulation of cellular component biogenesis WBGene00003576
GO:0044087
IEA
PLAZA Integrative Orthologyregulation of cellular component biogenesis WBGene00003576
GO:0044085
IEA
PLAZA Integrative Orthologycellular component biogenesis YIL144W
GO:0051321
IEA
PLAZA Integrative Orthologymeiotic cell cycle SPBC11C11.03
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction WBGene00003576
GO:0034508
IEA
PLAZA Integrative Orthologycentromere complex assembly WBGene00003576
GO:0061458
IEA
PLAZA Integrative Orthologyreproductive system development WBGene00003576
GO:0007018
IEA
PLAZA Integrative Orthologymicrotubule-based movement WBGene00003576
GO:0045840
IEA
PLAZA Integrative Orthologypositive regulation of mitotic nuclear division WBGene00003576
GO:1902115
IEA
PLAZA Integrative Orthologyregulation of organelle assembly WBGene00003576
GO:0048513
IEA
PLAZA Integrative Orthologyanimal organ development WBGene00003576
GO:1902117
IEA
PLAZA Integrative Orthologypositive regulation of organelle assembly WBGene00003576
GO:0022607
IEA
PLAZA Integrative Orthologycellular component assembly YIL144W
GO:1903046
IEA
PLAZA Integrative Orthologymeiotic cell cycle process SPBC11C11.03
GO:1905820
IEA
PLAZA Integrative Orthologypositive regulation of chromosome separation WBGene00003576
GO:0070925
IEA
PLAZA Integrative Orthologyorganelle assembly WBGene00003576
GO:2001252
IEA
PLAZA Integrative Orthologypositive regulation of chromosome organization WBGene00003576

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0042802
IPI
Genome Projectidentical protein binding
GO:0042802
IPI
Gene Ontologyidentical protein binding7 8
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 5 7 8 9 10 11 12 13 14 15 16
GO:0005200
IBA
Genome Projectstructural constituent of cytoskeleton
GO:0019904
IEA
PLAZA Integrative Orthologyprotein domain specific binding WBGene00003576
GO:0044877
IEA
PLAZA Integrative Orthologyprotein-containing complex binding WBGene00003576

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0031262
IDA
Genome ProjectNdc80 complex
GO:0031262
IDA
Gene OntologyNdc80 complex5
GO:0016020
IDA
Genome Projectmembrane
GO:0016020
Gene Ontologymembrane17
GO:0005829
TAS
Genome Projectcytosol
GO:0005829
TAS
Gene Ontologycytosol
GO:0005813
IDA
Genome Projectcentrosome
GO:0005813
IDA
Gene Ontologycentrosome
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005654
IDA
Gene Ontologynucleoplasm
GO:0005634
TAS
Genome Projectnucleus
GO:0005634
TAS
Gene Ontologynucleus6
GO:0000942
IDA
Genome Projectcondensed nuclear chromosome outer kinetochore
GO:0000942
IDA
Gene Ontologycondensed nuclear chromosome outer kinetochore18
GO:0000777
IDA
Genome Projectcondensed chromosome kinetochore
GO:0000777
IDA
Gene Ontologycondensed chromosome kinetochore5
GO:0000776
IDA
Genome Projectkinetochore
GO:0000776
IDA
Gene Ontologykinetochore4 19
GO:0000775
TAS
Genome Projectchromosome, centromeric region
GO:0000775
TAS
Gene Ontologychromosome, centromeric region6
GO:0031617
IEA
PLAZA Integrative OrthologyNMS complex SPBC11C11.03

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR005550Kinetochore protein Ndc80

No MapMan annotations defined for this gene.
KeggID Description
K11547NDC80, HEC1, TID3; kinetochore protein NDC80
No chloroplast target sequence found.