Gene: ENSG00000079387 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000079387
Transcript Identifier
ENST00000549518
Gene Type
Coding gene
Location
12 : 48045322-48101472 : negative

Family Information

Homologous gene family
HOM02SEM000703
(61 genes in 25 species)
specific family

Descriptions

gene_descr
SUMO1/sentrin specific peptidase 1

Identifiers

Type Value
pidENSP00000447328
HGNC17927
UniprotQ9P0U3
RefSeq_mRNANM_001267594.1
EMBLCHEMBL1909484
EMBLAC074029
EMBLAF149770
EMBLAK292060
EMBLBC045639

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0097190
IMP
Genome Projectapoptotic signaling pathway
GO:0097190
IMP
Gene Ontologyapoptotic signaling pathway1
GO:0045944
IGI
Genome Projectpositive regulation of transcription by RNA polymerase II
GO:0045944
IGI
Gene Ontologypositive regulation of transcription by RNA polymerase II2
GO:0032435
IEA
Genome Projectnegative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0016926
IMP
Genome Projectprotein desumoylation
GO:0016926
IMP
Gene Ontologyprotein desumoylation3
GO:0016925
TAS
Genome Projectprotein sumoylation
GO:0016925
TAS
Gene Ontologyprotein sumoylation
GO:0010724
IEA
Genome Projectregulation of definitive erythrocyte differentiation
GO:0006919
IMP
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006919
IMP
Gene Ontologyactivation of cysteine-type endopeptidase activity involved in apoptotic process1
GO:0006508
TAS
Genome Projectproteolysis
GO:0006508
TAS
Gene Ontologyproteolysis4
GO:0031401
IEA
PLAZA Integrative Orthologypositive regulation of protein modification process ENSG00000163904
GO:0035204
IEA
PLAZA Integrative Orthologynegative regulation of lamellocyte differentiation FBgn0027603
GO:0031400
IEA
PLAZA Integrative Orthologynegative regulation of protein modification process ENSG00000163904
GO:0035203
IEA
PLAZA Integrative Orthologyregulation of lamellocyte differentiation FBgn0027603
GO:0031647
IEA
PLAZA Integrative Orthologyregulation of protein stability ENSG00000163904
GO:0031648
IEA
PLAZA Integrative Orthologyprotein destabilization ENSG00000163904
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction AT4G15880
GO:2000573
IEA
PLAZA Integrative Orthologypositive regulation of DNA biosynthetic process WBGene00006736
GO:0097549
IEA
PLAZA Integrative Orthologychromatin organization involved in negative regulation of transcription SPBC19G7.09
GO:0033036
IEA
PLAZA Integrative Orthologymacromolecule localization WBGene00006736
GO:0045596
IEA
PLAZA Integrative Orthologynegative regulation of cell differentiation FBgn0027603
GO:0009968
IEA
PLAZA Integrative Orthologynegative regulation of signal transduction FBgn0027603
GO:0032989
IEA
PLAZA Integrative Orthologycellular component morphogenesis FBgn0027603
GO:0009605
IEA
PLAZA Integrative Orthologyresponse to external stimulus FBgn0027603
GO:0048858
IEA
PLAZA Integrative Orthologycell projection morphogenesis FBgn0027603
GO:0048732
IEA
PLAZA Integrative Orthologygland development FBgn0027603
GO:0006342
IEA
PLAZA Integrative Orthologychromatin silencing SPBC19G7.09
GO:0099173
IEA
PLAZA Integrative Orthologypostsynapse organization FBgn0027603
GO:0032990
IEA
PLAZA Integrative Orthologycell part morphogenesis FBgn0027603
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis SPBC19G7.09
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization SPBC19G7.09
GO:0032879
IEA
PLAZA Integrative Orthologyregulation of localization WBGene00006736
GO:0010629
IEA
PLAZA Integrative Orthologynegative regulation of gene expression SPBC19G7.09
GO:0006259
IEA
PLAZA Integrative OrthologyDNA metabolic process WBGene00006736
GO:0050808
IEA
PLAZA Integrative Orthologysynapse organization FBgn0027603
GO:0032880
IEA
PLAZA Integrative Orthologyregulation of protein localization WBGene00006736
GO:0048608
IEA
PLAZA Integrative Orthologyreproductive structure development AT4G15880
GO:0070887
IEA
PLAZA Integrative Orthologycellular response to chemical stimulus FBgn0027603
GO:0030466
IEA
PLAZA Integrative Orthologychromatin silencing at silent mating-type cassette SPBC19G7.09
GO:0009628
IEA
PLAZA Integrative Orthologyresponse to abiotic stimulus FBgn0027603
GO:0002683
IEA
PLAZA Integrative Orthologynegative regulation of immune system process FBgn0027603
GO:0048831
IEA
PLAZA Integrative Orthologyregulation of shoot system development AT4G15880
GO:1903321
IEA
PLAZA Integrative Orthologynegative regulation of protein modification by small protein conjugation or removal ENSG00000163904
GO:1903320
IEA
PLAZA Integrative Orthologyregulation of protein modification by small protein conjugation or removal ENSG00000163904
GO:0120039
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection morphogenesis FBgn0027603
GO:1903322
IEA
PLAZA Integrative Orthologypositive regulation of protein modification by small protein conjugation or removal ENSG00000163904
GO:0120036
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection organization FBgn0027603
GO:0051276
IEA
PLAZA Integrative Orthologychromosome organization SPBC19G7.09
GO:1903707
IEA
PLAZA Integrative Orthologynegative regulation of hemopoiesis FBgn0027603
GO:0040029
IEA
PLAZA Integrative Orthologyregulation of gene expression, epigenetic SPBC19G7.09
GO:0048666
IEA
PLAZA Integrative Orthologyneuron development FBgn0027603
GO:0048667
IEA
PLAZA Integrative Orthologycell morphogenesis involved in neuron differentiation FBgn0027603
GO:0031175
IEA
PLAZA Integrative Orthologyneuron projection development FBgn0027603
GO:0016458
IEA
PLAZA Integrative Orthologygene silencing SPBC19G7.09
GO:0016358
IEA
PLAZA Integrative Orthologydendrite development FBgn0027603
GO:0019985
IEA
PLAZA Integrative Orthologytranslesion synthesis WBGene00006736
GO:0048542
IEA
PLAZA Integrative Orthologylymph gland development FBgn0027603
GO:0006301
IEA
PLAZA Integrative Orthologypostreplication repair WBGene00006736
GO:0016485
IEA
PLAZA Integrative Orthologyprotein processing SPBC19G7.09
GO:0050727
IEA
PLAZA Integrative Orthologyregulation of inflammatory response FBgn0027603
GO:0051253
IEA
PLAZA Integrative Orthologynegative regulation of RNA metabolic process SPBC19G7.09
GO:0007417
IEA
PLAZA Integrative Orthologycentral nervous system development FBgn0027603
GO:0060997
IEA
PLAZA Integrative Orthologydendritic spine morphogenesis FBgn0027603
GO:0060996
IEA
PLAZA Integrative Orthologydendritic spine development FBgn0027603
GO:0009966
IEA
PLAZA Integrative Orthologyregulation of signal transduction FBgn0027603
GO:0045934
IEA
PLAZA Integrative Orthologynegative regulation of nucleobase-containing compound metabolic process SPBC19G7.09
GO:0000902
IEA
PLAZA Integrative Orthologycell morphogenesis FBgn0027603
GO:0050728
IEA
PLAZA Integrative Orthologynegative regulation of inflammatory response FBgn0027603
GO:0000904
IEA
PLAZA Integrative Orthologycell morphogenesis involved in differentiation FBgn0027603
GO:0045814
IEA
PLAZA Integrative Orthologynegative regulation of gene expression, epigenetic SPBC19G7.09
GO:0071897
IEA
PLAZA Integrative OrthologyDNA biosynthetic process WBGene00006736
GO:0051241
IEA
PLAZA Integrative Orthologynegative regulation of multicellular organismal process FBgn0027603
GO:0007409
IEA
PLAZA Integrative Orthologyaxonogenesis FBgn0027603
GO:0051240
IEA
PLAZA Integrative Orthologypositive regulation of multicellular organismal process AT4G15880
GO:0001666
IEA
PLAZA Integrative Orthologyresponse to hypoxia FBgn0027603
GO:0006325
IEA
PLAZA Integrative Orthologychromatin organization SPBC19G7.09
GO:0021954
IEA
PLAZA Integrative Orthologycentral nervous system neuron development FBgn0027603
GO:0022008
IEA
PLAZA Integrative Orthologyneurogenesis FBgn0027603
GO:0021953
IEA
PLAZA Integrative Orthologycentral nervous system neuron differentiation FBgn0027603
GO:0021952
IEA
PLAZA Integrative Orthologycentral nervous system projection neuron axonogenesis FBgn0027603
GO:0080135
IEA
PLAZA Integrative Orthologyregulation of cellular response to stress WBGene00006736
GO:0080134
IEA
PLAZA Integrative Orthologyregulation of response to stress WBGene00006736
GO:1904333
IEA
PLAZA Integrative Orthologypositive regulation of error-prone translesion synthesis WBGene00006736
GO:0044839
IEA
PLAZA Integrative Orthologycell cycle G2/M phase transition YPL020C
GO:0021955
IEA
PLAZA Integrative Orthologycentral nervous system neuron axonogenesis FBgn0027603
GO:0008063
IEA
PLAZA Integrative OrthologyToll signaling pathway FBgn0027603
GO:1904331
IEA
PLAZA Integrative Orthologyregulation of error-prone translesion synthesis WBGene00006736
GO:0007049
IEA
PLAZA Integrative Orthologycell cycle YPL020C
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization SPBC19G7.09
GO:0035171
IEA
PLAZA Integrative Orthologylamellocyte differentiation FBgn0027603
GO:0048468
IEA
PLAZA Integrative Orthologycell development FBgn0027603
GO:0007166
IEA
PLAZA Integrative Orthologycell surface receptor signaling pathway FBgn0027603
GO:0045751
IEA
PLAZA Integrative Orthologynegative regulation of Toll signaling pathway FBgn0027603
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process AT4G15880
GO:0048580
IEA
PLAZA Integrative Orthologyregulation of post-embryonic development AT4G15880
GO:0032101
IEA
PLAZA Integrative Orthologyregulation of response to external stimulus FBgn0027603
GO:0010558
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule biosynthetic process SPBC19G7.09
GO:0033554
IEA
PLAZA Integrative Orthologycellular response to stress WBGene00006736
GO:0034401
IEA
PLAZA Integrative Orthologychromatin organization involved in regulation of transcription SPBC19G7.09
GO:0032102
IEA
PLAZA Integrative Orthologynegative regulation of response to external stimulus FBgn0027603
GO:0048585
IEA
PLAZA Integrative Orthologynegative regulation of response to stimulus FBgn0027603
GO:0048581
IEA
PLAZA Integrative Orthologynegative regulation of post-embryonic development FBgn0027603
GO:0000086
IEA
PLAZA Integrative OrthologyG2/M transition of mitotic cell cycle YPL020C
GO:0048582
IEA
PLAZA Integrative Orthologypositive regulation of post-embryonic development AT4G15880
GO:0048583
IEA
PLAZA Integrative Orthologyregulation of response to stimulus WBGene00006736
GO:0048584
IEA
PLAZA Integrative Orthologypositive regulation of response to stimulus WBGene00006736
GO:1903507
IEA
PLAZA Integrative Orthologynegative regulation of nucleic acid-templated transcription SPBC19G7.09
GO:0048699
IEA
PLAZA Integrative Orthologygeneration of neurons FBgn0027603
GO:0044772
IEA
PLAZA Integrative Orthologymitotic cell cycle phase transition YPL020C
GO:0007399
IEA
PLAZA Integrative Orthologynervous system development FBgn0027603
GO:0016567
IEA
PLAZA Integrative Orthologyprotein ubiquitination ENSG00000163904
GO:0106027
IEA
PLAZA Integrative Orthologyneuron projection organization FBgn0027603
GO:0051054
IEA
PLAZA Integrative Orthologypositive regulation of DNA metabolic process WBGene00006736
GO:0044770
IEA
PLAZA Integrative Orthologycell cycle phase transition YPL020C
GO:0051179
IEA
PLAZA Integrative Orthologylocalization WBGene00006736
GO:0045613
IEA
PLAZA Integrative Orthologyregulation of plasmatocyte differentiation FBgn0027603
GO:0045614
IEA
PLAZA Integrative Orthologynegative regulation of plasmatocyte differentiation FBgn0027603
GO:0097061
IEA
PLAZA Integrative Orthologydendritic spine organization FBgn0027603
GO:0048569
IEA
PLAZA Integrative Orthologypost-embryonic animal organ development FBgn0027603
GO:0045611
IEA
PLAZA Integrative Orthologynegative regulation of hemocyte differentiation FBgn0027603
GO:0042221
IEA
PLAZA Integrative Orthologyresponse to chemical FBgn0027603
GO:0045610
IEA
PLAZA Integrative Orthologyregulation of hemocyte differentiation FBgn0027603
GO:0030182
IEA
PLAZA Integrative Orthologyneuron differentiation FBgn0027603
GO:2001022
IEA
PLAZA Integrative Orthologypositive regulation of response to DNA damage stimulus WBGene00006736
GO:2001020
IEA
PLAZA Integrative Orthologyregulation of response to DNA damage stimulus WBGene00006736
GO:0045739
IEA
PLAZA Integrative Orthologypositive regulation of DNA repair WBGene00006736
GO:0071456
IEA
PLAZA Integrative Orthologycellular response to hypoxia FBgn0027603
GO:0031397
IEA
PLAZA Integrative Orthologynegative regulation of protein ubiquitination ENSG00000163904
GO:0031396
IEA
PLAZA Integrative Orthologyregulation of protein ubiquitination ENSG00000163904
GO:0051604
IEA
PLAZA Integrative Orthologyprotein maturation SPBC19G7.09
GO:0031399
IEA
PLAZA Integrative Orthologyregulation of protein modification process ENSG00000163904
GO:2000278
IEA
PLAZA Integrative Orthologyregulation of DNA biosynthetic process WBGene00006736
GO:0031398
IEA
PLAZA Integrative Orthologypositive regulation of protein ubiquitination ENSG00000163904
GO:0009908
IEA
PLAZA Integrative Orthologyflower development AT4G15880
GO:0071453
IEA
PLAZA Integrative Orthologycellular response to oxygen levels FBgn0027603
GO:0009909
IEA
PLAZA Integrative Orthologyregulation of flower development AT4G15880
GO:0070482
IEA
PLAZA Integrative Orthologyresponse to oxygen levels FBgn0027603
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction AT4G15880
GO:0009911
IEA
PLAZA Integrative Orthologypositive regulation of flower development AT4G15880
GO:0002164
IEA
PLAZA Integrative Orthologylarval development FBgn0027603
GO:0036293
IEA
PLAZA Integrative Orthologyresponse to decreased oxygen levels FBgn0027603
GO:0051052
IEA
PLAZA Integrative Orthologyregulation of DNA metabolic process WBGene00006736
GO:0036294
IEA
PLAZA Integrative Orthologycellular response to decreased oxygen levels FBgn0027603
GO:1903047
IEA
PLAZA Integrative Orthologymitotic cell cycle process YPL020C
GO:0010646
IEA
PLAZA Integrative Orthologyregulation of cell communication FBgn0027603
GO:0010648
IEA
PLAZA Integrative Orthologynegative regulation of cell communication FBgn0027603
GO:0031327
IEA
PLAZA Integrative Orthologynegative regulation of cellular biosynthetic process SPBC19G7.09
GO:0006950
IEA
PLAZA Integrative Orthologyresponse to stress WBGene00006736
GO:0006952
IEA
PLAZA Integrative Orthologydefense response FBgn0027603
GO:0090567
IEA
PLAZA Integrative Orthologyreproductive shoot system development AT4G15880
GO:0048813
IEA
PLAZA Integrative Orthologydendrite morphogenesis FBgn0027603
GO:0000278
IEA
PLAZA Integrative Orthologymitotic cell cycle YPL020C
GO:0009653
IEA
PLAZA Integrative Orthologyanatomical structure morphogenesis FBgn0027603
GO:0042276
IEA
PLAZA Integrative Orthologyerror-prone translesion synthesis WBGene00006736
GO:0048812
IEA
PLAZA Integrative Orthologyneuron projection morphogenesis FBgn0027603
GO:0009890
IEA
PLAZA Integrative Orthologynegative regulation of biosynthetic process SPBC19G7.09
GO:0031348
IEA
PLAZA Integrative Orthologynegative regulation of defense response FBgn0027603
GO:0031347
IEA
PLAZA Integrative Orthologyregulation of defense response FBgn0027603
GO:2000243
IEA
PLAZA Integrative Orthologypositive regulation of reproductive process AT4G15880
GO:0023051
IEA
PLAZA Integrative Orthologyregulation of signaling FBgn0027603
GO:0023057
IEA
PLAZA Integrative Orthologynegative regulation of signaling FBgn0027603
GO:0006974
IEA
PLAZA Integrative Orthologycellular response to DNA damage stimulus WBGene00006736
GO:0042387
IEA
PLAZA Integrative Orthologyplasmatocyte differentiation FBgn0027603
GO:0042386
IEA
PLAZA Integrative Orthologyhemocyte differentiation FBgn0027603
GO:0008592
IEA
PLAZA Integrative Orthologyregulation of Toll signaling pathway FBgn0027603
GO:0061564
IEA
PLAZA Integrative Orthologyaxon development FBgn0027603
GO:2000113
IEA
PLAZA Integrative Orthologynegative regulation of cellular macromolecule biosynthetic process SPBC19G7.09
GO:0048367
IEA
PLAZA Integrative Orthologyshoot system development AT4G15880
GO:0045892
IEA
PLAZA Integrative Orthologynegative regulation of transcription, DNA-templated SPBC19G7.09
GO:0006954
IEA
PLAZA Integrative Orthologyinflammatory response FBgn0027603
GO:0061458
IEA
PLAZA Integrative Orthologyreproductive system development AT4G15880
GO:1902679
IEA
PLAZA Integrative Orthologynegative regulation of RNA biosynthetic process SPBC19G7.09
GO:0000731
IEA
PLAZA Integrative OrthologyDNA synthesis involved in DNA repair WBGene00006736
GO:0051094
IEA
PLAZA Integrative Orthologypositive regulation of developmental process AT4G15880
GO:0051093
IEA
PLAZA Integrative Orthologynegative regulation of developmental process FBgn0027603
GO:0008104
IEA
PLAZA Integrative Orthologyprotein localization WBGene00006736
GO:0022402
IEA
PLAZA Integrative Orthologycell cycle process YPL020C
GO:0030030
IEA
PLAZA Integrative Orthologycell projection organization FBgn0027603
GO:0009791
IEA
PLAZA Integrative Orthologypost-embryonic development AT4G15880
GO:0006282
IEA
PLAZA Integrative Orthologyregulation of DNA repair WBGene00006736
GO:0009792
IEA
PLAZA Integrative Orthologyembryo development ending in birth or egg hatching WBGene00006736
GO:2000241
IEA
PLAZA Integrative Orthologyregulation of reproductive process AT4G15880
GO:0035168
IEA
PLAZA Integrative Orthologylarval lymph gland hemocyte differentiation FBgn0027603
GO:0035167
IEA
PLAZA Integrative Orthologylarval lymph gland hemopoiesis FBgn0027603
GO:0035166
IEA
PLAZA Integrative Orthologypost-embryonic hemopoiesis FBgn0027603
GO:0006281
IEA
PLAZA Integrative OrthologyDNA repair WBGene00006736
GO:0009790
IEA
PLAZA Integrative Orthologyembryo development WBGene00006736

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0070139
EXP
Genome ProjectSUMO-specific endopeptidase activity
GO:0070139
EXP
Gene OntologySUMO-specific endopeptidase activity5 6
GO:0016929
ISS, IBA
Genome ProjectSUMO-specific protease activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding3 7 8
GO:0004175
TAS
Genome Projectendopeptidase activity
GO:0004175
TAS
Gene Ontologyendopeptidase activity4
GO:0070140
ISS
Gene OntologySUMO-specific isopeptidase activity
GO:0019899
IEA
PLAZA Integrative Orthologyenzyme binding AT4G15880
GO:0019900
IEA
PLAZA Integrative Orthologykinase binding AT4G15880

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0031965
IDA
Genome Projectnuclear membrane
GO:0031965
IDA
Gene Ontologynuclear membrane
GO:0005925
IDA
Genome Projectfocal adhesion
GO:0005925
IDA
Gene Ontologyfocal adhesion
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005654
TAS
Gene Ontologynucleoplasm
GO:0005634
IDA
IBA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus
GO:0055044
IEA
PLAZA Integrative Orthologysymplast AT3G06910
GO:0032991
IEA
PLAZA Integrative Orthologyprotein-containing complex YPL020C
GO:0005829
IEA
PLAZA Integrative Orthologycytosol SPBC19G7.09
GO:0009506
IEA
PLAZA Integrative Orthologyplasmodesma AT3G06910
GO:0009507
IEA
PLAZA Integrative Orthologychloroplast AT4G00690
GO:0019866
IEA
PLAZA Integrative Orthologyorganelle inner membrane FBgn0027603
GO:0005911
IEA
PLAZA Integrative Orthologycell-cell junction AT3G06910
GO:0034399
IEA
PLAZA Integrative Orthologynuclear periphery SPBC19G7.09
GO:0009536
IEA
PLAZA Integrative Orthologyplastid AT4G00690
GO:0005730
IEA
PLAZA Integrative Orthologynucleolus YPL020C
GO:0005637
IEA
PLAZA Integrative Orthologynuclear inner membrane FBgn0027603
GO:0005643
IEA
PLAZA Integrative Orthologynuclear pore YPL020C
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part SPBC19G7.09
GO:0043232
IEA
PLAZA Integrative Orthologyintracellular non-membrane-bounded organelle YPL020C
GO:0043228
IEA
PLAZA Integrative Orthologynon-membrane-bounded organelle YPL020C

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR003653Ulp1 protease family, C-terminal catalytic domain

No MapMan annotations defined for this gene.
KeggID Description
K08592SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
No chloroplast target sequence found.