Gene: ENSG00000077150 (Homo sapiens)

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Gene Identifier
ENSG00000077150
Transcript Identifier
ENST00000369966
Gene Type
Coding gene
Location
10 : 102395960-102402376 : positive

Family Information

Homologous gene family
HOM02SEM004776
(17 genes in 4 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

Identifiers

Type Value
pidENSP00000358983
HGNC7795
UniprotQ00653
RefSeq_mRNANM_001077494.3

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0051092
TAS
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0051092
TAS
Gene Ontologypositive regulation of NF-kappaB transcription factor activity
GO:0048536
IEA
Genome Projectspleen development
GO:0048511
IEA
Genome Projectrhythmic process
GO:0045944
IDA
Genome Projectpositive regulation of transcription by RNA polymerase II
GO:0045944
IDA
Gene Ontologypositive regulation of transcription by RNA polymerase II1
GO:0045087
IBA
Genome Projectinnate immune response
GO:0038061
IBA
TAS
Genome ProjectNIK/NF-kappaB signaling
GO:0038061
TAS
Gene OntologyNIK/NF-kappaB signaling
GO:0034097
IBA
Genome Projectresponse to cytokine
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0032481
TAS
Genome Projectpositive regulation of type I interferon production
GO:0032481
TAS
Gene Ontologypositive regulation of type I interferon production
GO:0030198
IEA
Genome Projectextracellular matrix organization
GO:0007568
IEA
Genome Projectaging
GO:0007249
IBA
Genome ProjectI-kappaB kinase/NF-kappaB signaling
GO:0006954
IBA
Genome Projectinflammatory response
GO:0006366
IEA
Genome Projecttranscription by RNA polymerase II
GO:0006355
IDA
Genome Projectregulation of transcription, DNA-templated
GO:0006355
IDA
Gene Ontologyregulation of transcription, DNA-templated2
GO:0002467
IEA
Genome Projectgerminal center formation
GO:0002268
IEA
Genome Projectfollicular dendritic cell differentiation
GO:0000122
IBA
Genome Projectnegative regulation of transcription by RNA polymerase II
GO:0010817
IEA
PLAZA Integrative Orthologyregulation of hormone levels ENSG00000109320
GO:0051246
IEA
PLAZA Integrative Orthologyregulation of protein metabolic process ENSG00000109320
GO:0002429
IEA
PLAZA Integrative Orthologyimmune response-activating cell surface receptor signaling pathway ENSG00000109320
GO:0043066
IEA
PLAZA Integrative Orthologynegative regulation of apoptotic process ENSG00000109320
GO:0002788
IEA
PLAZA Integrative Orthologyregulation of antifungal peptide production FBgn0014018
GO:0002786
IEA
PLAZA Integrative Orthologyregulation of antibacterial peptide production FBgn0014018
GO:1901615
IEA
PLAZA Integrative Orthologyorganic hydroxy compound metabolic process ENSG00000109320
GO:0046209
IEA
PLAZA Integrative Orthologynitric oxide metabolic process FBgn0014018
GO:0198738
IEA
PLAZA Integrative Orthologycell-cell signaling by wnt ENSG00000109320
GO:0043299
IEA
PLAZA Integrative Orthologyleukocyte degranulation ENSG00000109320
GO:0045597
IEA
PLAZA Integrative Orthologypositive regulation of cell differentiation ENSG00000109320
GO:0044267
IEA
PLAZA Integrative Orthologycellular protein metabolic process ENSG00000109320
GO:0035690
IEA
PLAZA Integrative Orthologycellular response to drug ENSG00000109320
GO:0031098
IEA
PLAZA Integrative Orthologystress-activated protein kinase signaling cascade ENSG00000109320
GO:0050829
IEA
PLAZA Integrative Orthologydefense response to Gram-negative bacterium FBgn0014018
GO:0050810
IEA
PLAZA Integrative Orthologyregulation of steroid biosynthetic process ENSG00000109320
GO:0033036
IEA
PLAZA Integrative Orthologymacromolecule localization ENSG00000109320
GO:0034248
IEA
PLAZA Integrative Orthologyregulation of cellular amide metabolic process FBgn0014018
GO:0002778
IEA
PLAZA Integrative Orthologyantibacterial peptide production FBgn0014018
GO:0045595
IEA
PLAZA Integrative Orthologyregulation of cell differentiation ENSG00000109320
GO:0002777
IEA
PLAZA Integrative Orthologyantimicrobial peptide biosynthetic process FBgn0014018
GO:0002775
IEA
PLAZA Integrative Orthologyantimicrobial peptide production FBgn0014018
GO:0002784
IEA
PLAZA Integrative Orthologyregulation of antimicrobial peptide production FBgn0014018
GO:0048858
IEA
PLAZA Integrative Orthologycell projection morphogenesis FBgn0014018
GO:0002783
IEA
PLAZA Integrative Orthologyantifungal peptide biosynthetic process FBgn0014018
GO:0002780
IEA
PLAZA Integrative Orthologyantibacterial peptide biosynthetic process FBgn0014018
GO:0002781
IEA
PLAZA Integrative Orthologyantifungal peptide production FBgn0014018
GO:1902931
IEA
PLAZA Integrative Orthologynegative regulation of alcohol biosynthetic process ENSG00000109320
GO:1902930
IEA
PLAZA Integrative Orthologyregulation of alcohol biosynthetic process ENSG00000109320
GO:0015850
IEA
PLAZA Integrative Orthologyorganic hydroxy compound transport ENSG00000109320
GO:0006809
IEA
PLAZA Integrative Orthologynitric oxide biosynthetic process FBgn0014018
GO:0034250
IEA
PLAZA Integrative Orthologypositive regulation of cellular amide metabolic process FBgn0014018
GO:0104004
IEA
PLAZA Integrative Orthologycellular response to environmental stimulus ENSG00000109320
GO:0000271
IEA
PLAZA Integrative Orthologypolysaccharide biosynthetic process ENSG00000109320
GO:0043043
IEA
PLAZA Integrative Orthologypeptide biosynthetic process FBgn0014018
GO:0002446
IEA
PLAZA Integrative Orthologyneutrophil mediated immunity ENSG00000109320
GO:0006810
IEA
PLAZA Integrative Orthologytransport ENSG00000109320
GO:0002444
IEA
PLAZA Integrative Orthologymyeloid leukocyte mediated immunity ENSG00000109320
GO:0090263
IEA
PLAZA Integrative Orthologypositive regulation of canonical Wnt signaling pathway ENSG00000109320
GO:0070887
IEA
PLAZA Integrative Orthologycellular response to chemical stimulus ENSG00000109320
GO:0006915
IEA
PLAZA Integrative Orthologyapoptotic process ENSG00000109320
GO:0002443
IEA
PLAZA Integrative Orthologyleukocyte mediated immunity ENSG00000109320
GO:0023014
IEA
PLAZA Integrative Orthologysignal transduction by protein phosphorylation ENSG00000109320
GO:0002684
IEA
PLAZA Integrative Orthologypositive regulation of immune system process ENSG00000109320
GO:0002440
IEA
PLAZA Integrative Orthologyproduction of molecular mediator of immune response FBgn0014018
GO:0002682
IEA
PLAZA Integrative Orthologyregulation of immune system process ENSG00000109320
GO:1901701
IEA
PLAZA Integrative Orthologycellular response to oxygen-containing compound ENSG00000109320
GO:0036211
IEA
PLAZA Integrative Orthologyprotein modification process ENSG00000109320
GO:0010243
IEA
PLAZA Integrative Orthologyresponse to organonitrogen compound ENSG00000109320
GO:0032375
IEA
PLAZA Integrative Orthologynegative regulation of cholesterol transport ENSG00000109320
GO:0048666
IEA
PLAZA Integrative Orthologyneuron development FBgn0014018
GO:0009267
IEA
PLAZA Integrative Orthologycellular response to starvation FBgn0014018
GO:1901652
IEA
PLAZA Integrative Orthologyresponse to peptide ENSG00000109320
GO:0048667
IEA
PLAZA Integrative Orthologycell morphogenesis involved in neuron differentiation FBgn0014018
GO:1901653
IEA
PLAZA Integrative Orthologycellular response to peptide ENSG00000109320
GO:0031293
IEA
PLAZA Integrative Orthologymembrane protein intracellular domain proteolysis ENSG00000109320
GO:0031175
IEA
PLAZA Integrative Orthologyneuron projection development FBgn0014018
GO:0032269
IEA
PLAZA Integrative Orthologynegative regulation of cellular protein metabolic process ENSG00000109320
GO:0071316
IEA
PLAZA Integrative Orthologycellular response to nicotine ENSG00000109320
GO:0050852
IEA
PLAZA Integrative OrthologyT cell receptor signaling pathway ENSG00000109320
GO:0032268
IEA
PLAZA Integrative Orthologyregulation of cellular protein metabolic process ENSG00000109320
GO:0071310
IEA
PLAZA Integrative Orthologycellular response to organic substance ENSG00000109320
GO:0050851
IEA
PLAZA Integrative Orthologyantigen receptor-mediated signaling pathway ENSG00000109320
GO:0060548
IEA
PLAZA Integrative Orthologynegative regulation of cell death ENSG00000109320
GO:0008285
IEA
PLAZA Integrative Orthologynegative regulation of cell proliferation FBgn0014018
GO:0008283
IEA
PLAZA Integrative Orthologycell proliferation FBgn0014018
GO:0070555
IEA
PLAZA Integrative Orthologyresponse to interleukin-1 ENSG00000109320
GO:2000647
IEA
PLAZA Integrative Orthologynegative regulation of stem cell proliferation FBgn0014018
GO:0002768
IEA
PLAZA Integrative Orthologyimmune response-regulating cell surface receptor signaling pathway ENSG00000109320
GO:0043086
IEA
PLAZA Integrative Orthologynegative regulation of catalytic activity ENSG00000109320
GO:0002764
IEA
PLAZA Integrative Orthologyimmune response-regulating signaling pathway ENSG00000109320
GO:0061844
IEA
PLAZA Integrative Orthologyantimicrobial humoral immune response mediated by antimicrobial peptide FBgn0014018
GO:1900426
IEA
PLAZA Integrative Orthologypositive regulation of defense response to bacterium FBgn0014018
GO:1900424
IEA
PLAZA Integrative Orthologyregulation of defense response to bacterium FBgn0014018
GO:2000630
IEA
PLAZA Integrative Orthologypositive regulation of miRNA metabolic process ENSG00000109320
GO:1990928
IEA
PLAZA Integrative Orthologyresponse to amino acid starvation FBgn0014018
GO:0050832
IEA
PLAZA Integrative Orthologydefense response to fungus FBgn0014018
GO:0071417
IEA
PLAZA Integrative Orthologycellular response to organonitrogen compound ENSG00000109320
GO:0002759
IEA
PLAZA Integrative Orthologyregulation of antimicrobial humoral response FBgn0014018
GO:0002758
IEA
PLAZA Integrative Orthologyinnate immune response-activating signal transduction ENSG00000109320
GO:0002757
IEA
PLAZA Integrative Orthologyimmune response-activating signal transduction ENSG00000109320
GO:0044283
IEA
PLAZA Integrative Orthologysmall molecule biosynthetic process ENSG00000109320
GO:0044281
IEA
PLAZA Integrative Orthologysmall molecule metabolic process ENSG00000109320
GO:1901617
IEA
PLAZA Integrative Orthologyorganic hydroxy compound biosynthetic process ENSG00000109320
GO:0043069
IEA
PLAZA Integrative Orthologynegative regulation of programmed cell death ENSG00000109320
GO:0002760
IEA
PLAZA Integrative Orthologypositive regulation of antimicrobial humoral response FBgn0014018
GO:0022008
IEA
PLAZA Integrative Orthologyneurogenesis FBgn0014018
GO:0043067
IEA
PLAZA Integrative Orthologyregulation of programmed cell death ENSG00000109320
GO:0080134
IEA
PLAZA Integrative Orthologyregulation of response to stress ENSG00000109320
GO:0008063
IEA
PLAZA Integrative OrthologyToll signaling pathway FBgn0014018
GO:0012501
IEA
PLAZA Integrative Orthologyprogrammed cell death ENSG00000109320
GO:0042493
IEA
PLAZA Integrative Orthologyresponse to drug ENSG00000109320
GO:0002702
IEA
PLAZA Integrative Orthologypositive regulation of production of molecular mediator of immune response FBgn0014018
GO:0002700
IEA
PLAZA Integrative Orthologyregulation of production of molecular mediator of immune response FBgn0014018
GO:2000628
IEA
PLAZA Integrative Orthologyregulation of miRNA metabolic process ENSG00000109320
GO:0042127
IEA
PLAZA Integrative Orthologyregulation of cell proliferation FBgn0014018
GO:0042368
IEA
PLAZA Integrative Orthologyvitamin D biosynthetic process ENSG00000109320
GO:0007166
IEA
PLAZA Integrative Orthologycell surface receptor signaling pathway ENSG00000109320
GO:0032101
IEA
PLAZA Integrative Orthologyregulation of response to external stimulus FBgn0014018
GO:0032103
IEA
PLAZA Integrative Orthologypositive regulation of response to external stimulus FBgn0014018
GO:0033554
IEA
PLAZA Integrative Orthologycellular response to stress ENSG00000109320
GO:0042362
IEA
PLAZA Integrative Orthologyfat-soluble vitamin biosynthetic process ENSG00000109320
GO:0002813
IEA
PLAZA Integrative Orthologyregulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria FBgn0014018
GO:0002812
IEA
PLAZA Integrative Orthologybiosynthetic process of antibacterial peptides active against Gram-negative bacteria FBgn0014018
GO:0002810
IEA
PLAZA Integrative Orthologyregulation of antifungal peptide biosynthetic process FBgn0014018
GO:0042359
IEA
PLAZA Integrative Orthologyvitamin D metabolic process ENSG00000109320
GO:0006066
IEA
PLAZA Integrative Orthologyalcohol metabolic process ENSG00000109320
GO:0007399
IEA
PLAZA Integrative Orthologynervous system development FBgn0014018
GO:0042594
IEA
PLAZA Integrative Orthologyresponse to starvation FBgn0014018
GO:0032350
IEA
PLAZA Integrative Orthologyregulation of hormone metabolic process ENSG00000109320
GO:0032351
IEA
PLAZA Integrative Orthologynegative regulation of hormone metabolic process ENSG00000109320
GO:0042119
IEA
PLAZA Integrative Orthologyneutrophil activation ENSG00000109320
GO:0010586
IEA
PLAZA Integrative OrthologymiRNA metabolic process ENSG00000109320
GO:0032353
IEA
PLAZA Integrative Orthologynegative regulation of hormone biosynthetic process ENSG00000109320
GO:0030177
IEA
PLAZA Integrative Orthologypositive regulation of Wnt signaling pathway ENSG00000109320
GO:0015918
IEA
PLAZA Integrative Orthologysterol transport ENSG00000109320
GO:0051055
IEA
PLAZA Integrative Orthologynegative regulation of lipid biosynthetic process ENSG00000109320
GO:0051179
IEA
PLAZA Integrative Orthologylocalization ENSG00000109320
GO:0043436
IEA
PLAZA Integrative Orthologyoxoacid metabolic process ENSG00000109320
GO:0043434
IEA
PLAZA Integrative Orthologyresponse to peptide hormone ENSG00000109320
GO:0043312
IEA
PLAZA Integrative Orthologyneutrophil degranulation ENSG00000109320
GO:1905114
IEA
PLAZA Integrative Orthologycell surface receptor signaling pathway involved in cell-cell signaling ENSG00000109320
GO:0034660
IEA
PLAZA Integrative OrthologyncRNA metabolic process ENSG00000109320
GO:0030182
IEA
PLAZA Integrative Orthologyneuron differentiation FBgn0014018
GO:1904385
IEA
PLAZA Integrative Orthologycellular response to angiotensin ENSG00000109320
GO:0032369
IEA
PLAZA Integrative Orthologynegative regulation of lipid transport ENSG00000109320
GO:0032368
IEA
PLAZA Integrative Orthologyregulation of lipid transport ENSG00000109320
GO:0001505
IEA
PLAZA Integrative Orthologyregulation of neurotransmitter levels FBgn0014018
GO:0002831
IEA
PLAZA Integrative Orthologyregulation of response to biotic stimulus FBgn0014018
GO:0002833
IEA
PLAZA Integrative Orthologypositive regulation of response to biotic stimulus FBgn0014018
GO:0051051
IEA
PLAZA Integrative Orthologynegative regulation of transport ENSG00000109320
GO:0051049
IEA
PLAZA Integrative Orthologyregulation of transport ENSG00000109320
GO:0032371
IEA
PLAZA Integrative Orthologyregulation of sterol transport ENSG00000109320
GO:0032372
IEA
PLAZA Integrative Orthologynegative regulation of sterol transport ENSG00000109320
GO:0009110
IEA
PLAZA Integrative Orthologyvitamin biosynthetic process ENSG00000109320
GO:0032374
IEA
PLAZA Integrative Orthologyregulation of cholesterol transport ENSG00000109320
GO:0006082
IEA
PLAZA Integrative Orthologyorganic acid metabolic process ENSG00000109320
GO:0010883
IEA
PLAZA Integrative Orthologyregulation of lipid storage ENSG00000109320
GO:0071702
IEA
PLAZA Integrative Orthologyorganic substance transport ENSG00000109320
GO:0010884
IEA
PLAZA Integrative Orthologypositive regulation of lipid storage ENSG00000109320
GO:0019218
IEA
PLAZA Integrative Orthologyregulation of steroid metabolic process ENSG00000109320
GO:0019216
IEA
PLAZA Integrative Orthologyregulation of lipid metabolic process ENSG00000109320
GO:0030111
IEA
PLAZA Integrative Orthologyregulation of Wnt signaling pathway ENSG00000109320
GO:0010646
IEA
PLAZA Integrative Orthologyregulation of cell communication ENSG00000109320
GO:0045321
IEA
PLAZA Integrative Orthologyleukocyte activation ENSG00000109320
GO:0010647
IEA
PLAZA Integrative Orthologypositive regulation of cell communication ENSG00000109320
GO:0046890
IEA
PLAZA Integrative Orthologyregulation of lipid biosynthetic process ENSG00000109320
GO:0046885
IEA
PLAZA Integrative Orthologyregulation of hormone biosynthetic process ENSG00000109320
GO:0043255
IEA
PLAZA Integrative Orthologyregulation of carbohydrate biosynthetic process ENSG00000109320
GO:0010876
IEA
PLAZA Integrative Orthologylipid localization ENSG00000109320
GO:0019221
IEA
PLAZA Integrative Orthologycytokine-mediated signaling pathway ENSG00000109320
GO:0070741
IEA
PLAZA Integrative Orthologyresponse to interleukin-6 ENSG00000109320
GO:0016192
IEA
PLAZA Integrative Orthologyvesicle-mediated transport ENSG00000109320
GO:0060828
IEA
PLAZA Integrative Orthologyregulation of canonical Wnt signaling pathway ENSG00000109320
GO:0048934
IEA
PLAZA Integrative Orthologyperipheral nervous system neuron differentiation FBgn0014018
GO:0048813
IEA
PLAZA Integrative Orthologydendrite morphogenesis FBgn0014018
GO:0038093
IEA
PLAZA Integrative OrthologyFc receptor signaling pathway ENSG00000109320
GO:0048935
IEA
PLAZA Integrative Orthologyperipheral nervous system neuron development FBgn0014018
GO:0006023
IEA
PLAZA Integrative Orthologyaminoglycan biosynthetic process ENSG00000109320
GO:0045428
IEA
PLAZA Integrative Orthologyregulation of nitric oxide biosynthetic process FBgn0014018
GO:0008202
IEA
PLAZA Integrative Orthologysteroid metabolic process ENSG00000109320
GO:0006022
IEA
PLAZA Integrative Orthologyaminoglycan metabolic process ENSG00000109320
GO:0048812
IEA
PLAZA Integrative Orthologyneuron projection morphogenesis FBgn0014018
GO:0006024
IEA
PLAZA Integrative Orthologyglycosaminoglycan biosynthetic process ENSG00000109320
GO:0038095
IEA
PLAZA Integrative OrthologyFc-epsilon receptor signaling pathway ENSG00000109320
GO:0045429
IEA
PLAZA Integrative Orthologypositive regulation of nitric oxide biosynthetic process FBgn0014018
GO:0002808
IEA
PLAZA Integrative Orthologyregulation of antibacterial peptide biosynthetic process FBgn0014018
GO:0031347
IEA
PLAZA Integrative Orthologyregulation of defense response ENSG00000109320
GO:0002807
IEA
PLAZA Integrative Orthologypositive regulation of antimicrobial peptide biosynthetic process FBgn0014018
GO:0002805
IEA
PLAZA Integrative Orthologyregulation of antimicrobial peptide biosynthetic process FBgn0014018
GO:0002804
IEA
PLAZA Integrative Orthologypositive regulation of antifungal peptide production FBgn0014018
GO:0002803
IEA
PLAZA Integrative Orthologypositive regulation of antibacterial peptide production FBgn0014018
GO:0002922
IEA
PLAZA Integrative Orthologypositive regulation of humoral immune response FBgn0014018
GO:1990776
IEA
PLAZA Integrative Orthologyresponse to angiotensin ENSG00000109320
GO:0002920
IEA
PLAZA Integrative Orthologyregulation of humoral immune response FBgn0014018
GO:0031349
IEA
PLAZA Integrative Orthologypositive regulation of defense response ENSG00000109320
GO:0007267
IEA
PLAZA Integrative Orthologycell-cell signaling ENSG00000109320
GO:0065008
IEA
PLAZA Integrative Orthologyregulation of biological quality ENSG00000109320
GO:0010894
IEA
PLAZA Integrative Orthologynegative regulation of steroid biosynthetic process ENSG00000109320
GO:0008219
IEA
PLAZA Integrative Orthologycell death ENSG00000109320
GO:0042136
IEA
PLAZA Integrative Orthologyneurotransmitter biosynthetic process FBgn0014018
GO:0051094
IEA
PLAZA Integrative Orthologypositive regulation of developmental process ENSG00000109320
GO:0042133
IEA
PLAZA Integrative Orthologyneurotransmitter metabolic process FBgn0014018
GO:0030030
IEA
PLAZA Integrative Orthologycell projection organization FBgn0014018
GO:0051234
IEA
PLAZA Integrative Orthologyestablishment of localization ENSG00000109320
GO:0051354
IEA
PLAZA Integrative Orthologynegative regulation of oxidoreductase activity ENSG00000109320
GO:0051235
IEA
PLAZA Integrative Orthologymaintenance of location ENSG00000109320
GO:0006109
IEA
PLAZA Integrative Orthologyregulation of carbohydrate metabolic process ENSG00000109320
GO:0009620
IEA
PLAZA Integrative Orthologyresponse to fungus FBgn0014018
GO:0045913
IEA
PLAZA Integrative Orthologypositive regulation of carbohydrate metabolic process ENSG00000109320
GO:0030203
IEA
PLAZA Integrative Orthologyglycosaminoglycan metabolic process ENSG00000109320
GO:0060070
IEA
PLAZA Integrative Orthologycanonical Wnt signaling pathway ENSG00000109320
GO:0010957
IEA
PLAZA Integrative Orthologynegative regulation of vitamin D biosynthetic process ENSG00000109320
GO:0051341
IEA
PLAZA Integrative Orthologyregulation of oxidoreductase activity ENSG00000109320
GO:0010956
IEA
PLAZA Integrative Orthologynegative regulation of calcidiol 1-monooxygenase activity ENSG00000109320
GO:0032989
IEA
PLAZA Integrative Orthologycellular component morphogenesis FBgn0014018
GO:0009612
IEA
PLAZA Integrative Orthologyresponse to mechanical stimulus ENSG00000109320
GO:0009615
IEA
PLAZA Integrative Orthologyresponse to virus FBgn0014018
GO:0006468
IEA
PLAZA Integrative Orthologyprotein phosphorylation ENSG00000109320
GO:0006464
IEA
PLAZA Integrative Orthologycellular protein modification process ENSG00000109320
GO:0032990
IEA
PLAZA Integrative Orthologycell part morphogenesis FBgn0014018
GO:0043603
IEA
PLAZA Integrative Orthologycellular amide metabolic process FBgn0014018
GO:0019538
IEA
PLAZA Integrative Orthologyprotein metabolic process ENSG00000109320
GO:0043604
IEA
PLAZA Integrative Orthologyamide biosynthetic process FBgn0014018
GO:0031667
IEA
PLAZA Integrative Orthologyresponse to nutrient levels FBgn0014018
GO:0030212
IEA
PLAZA Integrative Orthologyhyaluronan metabolic process ENSG00000109320
GO:0030213
IEA
PLAZA Integrative Orthologyhyaluronan biosynthetic process ENSG00000109320
GO:0010744
IEA
PLAZA Integrative Orthologypositive regulation of macrophage derived foam cell differentiation ENSG00000109320
GO:0032870
IEA
PLAZA Integrative Orthologycellular response to hormone stimulus ENSG00000109320
GO:0010742
IEA
PLAZA Integrative Orthologymacrophage derived foam cell differentiation ENSG00000109320
GO:0010743
IEA
PLAZA Integrative Orthologyregulation of macrophage derived foam cell differentiation ENSG00000109320
GO:0031669
IEA
PLAZA Integrative Orthologycellular response to nutrient levels FBgn0014018
GO:0032879
IEA
PLAZA Integrative Orthologyregulation of localization ENSG00000109320
GO:0031668
IEA
PLAZA Integrative Orthologycellular response to extracellular stimulus FBgn0014018
GO:0098542
IEA
PLAZA Integrative Orthologydefense response to other organism FBgn0014018
GO:0042742
IEA
PLAZA Integrative Orthologydefense response to bacterium FBgn0014018
GO:0042981
IEA
PLAZA Integrative Orthologyregulation of apoptotic process ENSG00000109320
GO:0032885
IEA
PLAZA Integrative Orthologyregulation of polysaccharide biosynthetic process ENSG00000109320
GO:0032881
IEA
PLAZA Integrative Orthologyregulation of polysaccharide metabolic process ENSG00000109320
GO:0017144
IEA
PLAZA Integrative Orthologydrug metabolic process FBgn0014018
GO:0016055
IEA
PLAZA Integrative OrthologyWnt signaling pathway ENSG00000109320
GO:0016053
IEA
PLAZA Integrative Orthologyorganic acid biosynthetic process ENSG00000109320
GO:0033619
IEA
PLAZA Integrative Orthologymembrane protein proteolysis ENSG00000109320
GO:0016051
IEA
PLAZA Integrative Orthologycarbohydrate biosynthetic process ENSG00000109320
GO:0032769
IEA
PLAZA Integrative Orthologynegative regulation of monooxygenase activity ENSG00000109320
GO:0032768
IEA
PLAZA Integrative Orthologyregulation of monooxygenase activity ENSG00000109320
GO:0009628
IEA
PLAZA Integrative Orthologyresponse to abiotic stimulus ENSG00000109320
GO:0009636
IEA
PLAZA Integrative Orthologyresponse to toxic substance ENSG00000109320
GO:0120039
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection morphogenesis FBgn0014018
GO:0009991
IEA
PLAZA Integrative Orthologyresponse to extracellular stimulus FBgn0014018
GO:0120036
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection organization FBgn0014018
GO:0019732
IEA
PLAZA Integrative Orthologyantifungal humoral response FBgn0014018
GO:0019730
IEA
PLAZA Integrative Orthologyantimicrobial humoral response FBgn0014018
GO:0019731
IEA
PLAZA Integrative Orthologyantibacterial humoral response FBgn0014018
GO:0097237
IEA
PLAZA Integrative Orthologycellular response to toxic substance ENSG00000109320
GO:0045833
IEA
PLAZA Integrative Orthologynegative regulation of lipid metabolic process ENSG00000109320
GO:0042446
IEA
PLAZA Integrative Orthologyhormone biosynthetic process ENSG00000109320
GO:0042445
IEA
PLAZA Integrative Orthologyhormone metabolic process ENSG00000109320
GO:0006796
IEA
PLAZA Integrative Orthologyphosphate-containing compound metabolic process ENSG00000109320
GO:0043412
IEA
PLAZA Integrative Orthologymacromolecule modification ENSG00000109320
GO:0035094
IEA
PLAZA Integrative Orthologyresponse to nicotine ENSG00000109320
GO:0008610
IEA
PLAZA Integrative Orthologylipid biosynthetic process ENSG00000109320
GO:0006793
IEA
PLAZA Integrative Orthologyphosphorus metabolic process ENSG00000109320
GO:0016358
IEA
PLAZA Integrative Orthologydendrite development FBgn0014018
GO:0032940
IEA
PLAZA Integrative Orthologysecretion by cell ENSG00000109320
GO:0072089
IEA
PLAZA Integrative Orthologystem cell proliferation FBgn0014018
GO:0072091
IEA
PLAZA Integrative Orthologyregulation of stem cell proliferation FBgn0014018
GO:2001057
IEA
PLAZA Integrative Orthologyreactive nitrogen species metabolic process FBgn0014018
GO:0019752
IEA
PLAZA Integrative Orthologycarboxylic acid metabolic process ENSG00000109320
GO:0009719
IEA
PLAZA Integrative Orthologyresponse to endogenous stimulus ENSG00000109320
GO:0010941
IEA
PLAZA Integrative Orthologyregulation of cell death ENSG00000109320
GO:0030656
IEA
PLAZA Integrative Orthologyregulation of vitamin metabolic process ENSG00000109320
GO:0009966
IEA
PLAZA Integrative Orthologyregulation of signal transduction ENSG00000109320
GO:0009967
IEA
PLAZA Integrative Orthologypositive regulation of signal transduction ENSG00000109320
GO:0009725
IEA
PLAZA Integrative Orthologyresponse to hormone ENSG00000109320
GO:0006694
IEA
PLAZA Integrative Orthologysteroid biosynthetic process ENSG00000109320
GO:0007422
IEA
PLAZA Integrative Orthologyperipheral nervous system development FBgn0014018
GO:0062012
IEA
PLAZA Integrative Orthologyregulation of small molecule metabolic process ENSG00000109320
GO:0000902
IEA
PLAZA Integrative Orthologycell morphogenesis FBgn0014018
GO:0045939
IEA
PLAZA Integrative Orthologynegative regulation of steroid metabolic process ENSG00000109320
GO:0000904
IEA
PLAZA Integrative Orthologycell morphogenesis involved in differentiation FBgn0014018
GO:0046903
IEA
PLAZA Integrative Orthologysecretion ENSG00000109320
GO:0062014
IEA
PLAZA Integrative Orthologynegative regulation of small molecule metabolic process ENSG00000109320
GO:0062013
IEA
PLAZA Integrative Orthologypositive regulation of small molecule metabolic process ENSG00000109320
GO:1901699
IEA
PLAZA Integrative Orthologycellular response to nitrogen compound ENSG00000109320
GO:0051248
IEA
PLAZA Integrative Orthologynegative regulation of protein metabolic process ENSG00000109320
GO:0030301
IEA
PLAZA Integrative Orthologycholesterol transport ENSG00000109320
GO:0061059
IEA
PLAZA Integrative Orthologypositive regulation of peptidoglycan recognition protein signaling pathway FBgn0014018
GO:0061058
IEA
PLAZA Integrative Orthologyregulation of peptidoglycan recognition protein signaling pathway FBgn0014018
GO:0061057
IEA
PLAZA Integrative Orthologypeptidoglycan recognition protein signaling pathway FBgn0014018
GO:0070498
IEA
PLAZA Integrative Orthologyinterleukin-1-mediated signaling pathway ENSG00000109320
GO:0071345
IEA
PLAZA Integrative Orthologycellular response to cytokine stimulus ENSG00000109320
GO:0071347
IEA
PLAZA Integrative Orthologycellular response to interleukin-1 ENSG00000109320
GO:0006508
IEA
PLAZA Integrative Orthologyproteolysis ENSG00000109320
GO:0006629
IEA
PLAZA Integrative Orthologylipid metabolic process ENSG00000109320
GO:0045088
IEA
PLAZA Integrative Orthologyregulation of innate immune response ENSG00000109320
GO:0071222
IEA
PLAZA Integrative Orthologycellular response to lipopolysaccharide ENSG00000109320
GO:0045089
IEA
PLAZA Integrative Orthologypositive regulation of innate immune response ENSG00000109320
GO:0006869
IEA
PLAZA Integrative Orthologylipid transport ENSG00000109320
GO:0002275
IEA
PLAZA Integrative Orthologymyeloid cell activation involved in immune response ENSG00000109320
GO:1900127
IEA
PLAZA Integrative Orthologypositive regulation of hyaluronan biosynthetic process ENSG00000109320
GO:0048468
IEA
PLAZA Integrative Orthologycell development FBgn0014018
GO:1900125
IEA
PLAZA Integrative Orthologyregulation of hyaluronan biosynthetic process ENSG00000109320
GO:0002274
IEA
PLAZA Integrative Orthologymyeloid leukocyte activation ENSG00000109320
GO:1901698
IEA
PLAZA Integrative Orthologyresponse to nitrogen compound ENSG00000109320
GO:1903510
IEA
PLAZA Integrative Orthologymucopolysaccharide metabolic process ENSG00000109320
GO:0050776
IEA
PLAZA Integrative Orthologyregulation of immune response ENSG00000109320
GO:0050778
IEA
PLAZA Integrative Orthologypositive regulation of immune response ENSG00000109320
GO:0016310
IEA
PLAZA Integrative Orthologyphosphorylation ENSG00000109320
GO:0046165
IEA
PLAZA Integrative Orthologyalcohol biosynthetic process ENSG00000109320
GO:0048583
IEA
PLAZA Integrative Orthologyregulation of response to stimulus ENSG00000109320
GO:0071354
IEA
PLAZA Integrative Orthologycellular response to interleukin-6 ENSG00000109320
GO:0048699
IEA
PLAZA Integrative Orthologygeneration of neurons FBgn0014018
GO:0048584
IEA
PLAZA Integrative Orthologypositive regulation of response to stimulus ENSG00000109320
GO:1902533
IEA
PLAZA Integrative Orthologypositive regulation of intracellular signal transduction FBgn0014018
GO:1901566
IEA
PLAZA Integrative Orthologyorganonitrogen compound biosynthetic process ENSG00000109320
GO:0002263
IEA
PLAZA Integrative Orthologycell activation involved in immune response ENSG00000109320
GO:0090077
IEA
PLAZA Integrative Orthologyfoam cell differentiation ENSG00000109320
GO:1901564
IEA
PLAZA Integrative Orthologyorganonitrogen compound metabolic process ENSG00000109320
GO:1902531
IEA
PLAZA Integrative Orthologyregulation of intracellular signal transduction FBgn0014018
GO:0044092
IEA
PLAZA Integrative Orthologynegative regulation of molecular function ENSG00000109320
GO:0046394
IEA
PLAZA Integrative Orthologycarboxylic acid biosynthetic process ENSG00000109320
GO:0006775
IEA
PLAZA Integrative Orthologyfat-soluble vitamin metabolic process ENSG00000109320
GO:0060556
IEA
PLAZA Integrative Orthologyregulation of vitamin D biosynthetic process ENSG00000109320
GO:0071219
IEA
PLAZA Integrative Orthologycellular response to molecule of bacterial origin ENSG00000109320
GO:0060558
IEA
PLAZA Integrative Orthologyregulation of calcidiol 1-monooxygenase activity ENSG00000109320
GO:0051607
IEA
PLAZA Integrative Orthologydefense response to virus FBgn0014018
GO:0071214
IEA
PLAZA Integrative Orthologycellular response to abiotic stimulus ENSG00000109320
GO:0045055
IEA
PLAZA Integrative Orthologyregulated exocytosis ENSG00000109320
GO:0071216
IEA
PLAZA Integrative Orthologycellular response to biotic stimulus ENSG00000109320
GO:0006518
IEA
PLAZA Integrative Orthologypeptide metabolic process FBgn0014018
GO:0006766
IEA
PLAZA Integrative Orthologyvitamin metabolic process ENSG00000109320
GO:0006887
IEA
PLAZA Integrative Orthologyexocytosis ENSG00000109320
GO:0046137
IEA
PLAZA Integrative Orthologynegative regulation of vitamin metabolic process ENSG00000109320
GO:0002283
IEA
PLAZA Integrative Orthologyneutrophil activation involved in immune response ENSG00000109320
GO:0071260
IEA
PLAZA Integrative Orthologycellular response to mechanical stimulus ENSG00000109320
GO:0002225
IEA
PLAZA Integrative Orthologypositive regulation of antimicrobial peptide production FBgn0014018
GO:0072593
IEA
PLAZA Integrative Orthologyreactive oxygen species metabolic process FBgn0014018
GO:0005976
IEA
PLAZA Integrative Orthologypolysaccharide metabolic process ENSG00000109320
GO:0005975
IEA
PLAZA Integrative Orthologycarbohydrate metabolic process ENSG00000109320
GO:0002230
IEA
PLAZA Integrative Orthologypositive regulation of defense response to virus by host FBgn0014018
GO:1904407
IEA
PLAZA Integrative Orthologypositive regulation of nitric oxide metabolic process FBgn0014018
GO:1901137
IEA
PLAZA Integrative Orthologycarbohydrate derivative biosynthetic process ENSG00000109320
GO:1901135
IEA
PLAZA Integrative Orthologycarbohydrate derivative metabolic process ENSG00000109320
GO:2000379
IEA
PLAZA Integrative Orthologypositive regulation of reactive oxygen species metabolic process FBgn0014018
GO:2000377
IEA
PLAZA Integrative Orthologyregulation of reactive oxygen species metabolic process FBgn0014018
GO:0050691
IEA
PLAZA Integrative Orthologyregulation of defense response to virus by host FBgn0014018
GO:0071396
IEA
PLAZA Integrative Orthologycellular response to lipid ENSG00000109320
GO:0002218
IEA
PLAZA Integrative Orthologyactivation of innate immune response ENSG00000109320
GO:0002699
IEA
PLAZA Integrative Orthologypositive regulation of immune effector process FBgn0014018
GO:0000165
IEA
PLAZA Integrative OrthologyMAPK cascade ENSG00000109320
GO:0002697
IEA
PLAZA Integrative Orthologyregulation of immune effector process FBgn0014018
GO:1903428
IEA
PLAZA Integrative Orthologypositive regulation of reactive oxygen species biosynthetic process FBgn0014018
GO:0002223
IEA
PLAZA Integrative Orthologystimulatory C-type lectin receptor signaling pathway ENSG00000109320
GO:0002220
IEA
PLAZA Integrative Orthologyinnate immune response activating cell surface receptor signaling pathway ENSG00000109320
GO:1903426
IEA
PLAZA Integrative Orthologyregulation of reactive oxygen species biosynthetic process FBgn0014018
GO:0036230
IEA
PLAZA Integrative Orthologygranulocyte activation ENSG00000109320
GO:1900150
IEA
PLAZA Integrative Orthologyregulation of defense response to fungus FBgn0014018
GO:0050688
IEA
PLAZA Integrative Orthologyregulation of defense response to virus FBgn0014018
GO:0023051
IEA
PLAZA Integrative Orthologyregulation of signaling ENSG00000109320
GO:0023056
IEA
PLAZA Integrative Orthologypositive regulation of signaling ENSG00000109320
GO:1903409
IEA
PLAZA Integrative Orthologyreactive oxygen species biosynthetic process FBgn0014018
GO:0006967
IEA
PLAZA Integrative Orthologypositive regulation of antifungal peptide biosynthetic process FBgn0014018
GO:0006974
IEA
PLAZA Integrative Orthologycellular response to DNA damage stimulus FBgn0014018
GO:0002253
IEA
PLAZA Integrative Orthologyactivation of immune response ENSG00000109320
GO:1905953
IEA
PLAZA Integrative Orthologynegative regulation of lipid localization ENSG00000109320
GO:0002252
IEA
PLAZA Integrative Orthologyimmune effector process ENSG00000109320
GO:1905954
IEA
PLAZA Integrative Orthologypositive regulation of lipid localization ENSG00000109320
GO:1905952
IEA
PLAZA Integrative Orthologyregulation of lipid localization ENSG00000109320
GO:0051403
IEA
PLAZA Integrative Orthologystress-activated MAPK cascade ENSG00000109320
GO:0006959
IEA
PLAZA Integrative Orthologyhumoral immune response FBgn0014018
GO:0071496
IEA
PLAZA Integrative Orthologycellular response to external stimulus ENSG00000109320
GO:0050790
IEA
PLAZA Integrative Orthologyregulation of catalytic activity ENSG00000109320
GO:0071375
IEA
PLAZA Integrative Orthologycellular response to peptide hormone stimulus ENSG00000109320
GO:0071495
IEA
PLAZA Integrative Orthologycellular response to endogenous stimulus ENSG00000109320
GO:0050793
IEA
PLAZA Integrative Orthologyregulation of developmental process ENSG00000109320
GO:0002366
IEA
PLAZA Integrative Orthologyleukocyte activation involved in immune response ENSG00000109320
GO:0006964
IEA
PLAZA Integrative Orthologypositive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria FBgn0014018
GO:0006963
IEA
PLAZA Integrative Orthologypositive regulation of antibacterial peptide biosynthetic process FBgn0014018
GO:1901224
IEA
PLAZA Integrative Orthologypositive regulation of NIK/NF-kappaB signaling FBgn0014018
GO:1901222
IEA
PLAZA Integrative Orthologyregulation of NIK/NF-kappaB signaling FBgn0014018
GO:0034198
IEA
PLAZA Integrative Orthologycellular response to amino acid starvation FBgn0014018
GO:0043902
IEA
PLAZA Integrative Orthologypositive regulation of multi-organism process FBgn0014018
GO:0019915
IEA
PLAZA Integrative Orthologylipid storage ENSG00000109320
GO:0043900
IEA
PLAZA Integrative Orthologyregulation of multi-organism process FBgn0014018

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding3 4 5 6 7 8 9 10 11
GO:0003713
TAS
Genome Projecttranscription coactivator activity
GO:0003713
TAS
Gene Ontologytranscription coactivator activity12
GO:0003700
TAS
Genome ProjectDNA-binding transcription factor activity
GO:0003700
TAS
Gene OntologyDNA-binding transcription factor activity12 13
GO:0003682
IBA
Genome Projectchromatin binding
GO:0000978
IDA
Genome ProjectRNA polymerase II proximal promoter sequence-specific DNA binding
GO:0000978
IDA
Gene OntologyRNA polymerase II proximal promoter sequence-specific DNA binding1
GO:0035326
IEA
PLAZA Integrative Orthologyenhancer binding ENSG00000109320
GO:0008092
IEA
PLAZA Integrative Orthologycytoskeletal protein binding ENSG00000109320
GO:0001227
IEA
PLAZA Integrative OrthologyDNA-binding transcription repressor activity, RNA polymerase II-specific ENSG00000109320
GO:0008134
IEA
PLAZA Integrative Orthologytranscription factor binding ENSG00000109320
GO:0046983
IEA
PLAZA Integrative Orthologyprotein dimerization activity ENSG00000109320
GO:0046982
IEA
PLAZA Integrative Orthologyprotein heterodimerization activity ENSG00000109320
GO:0000980
IEA
PLAZA Integrative OrthologyRNA polymerase II distal enhancer sequence-specific DNA binding ENSG00000109320
GO:0042805
IEA
PLAZA Integrative Orthologyactinin binding ENSG00000109320
GO:0042802
IEA
PLAZA Integrative Orthologyidentical protein binding ENSG00000109320
GO:0001158
IEA
PLAZA Integrative Orthologyenhancer sequence-specific DNA binding ENSG00000109320
GO:0000981
ISA, ISM
NAS
Gene OntologyDNA-binding transcription factor activity, RNA polymerase II-specific14

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0033257
IDA
Genome ProjectBcl3/NF-kappaB2 complex
GO:0033257
IDA
Gene OntologyBcl3/NF-kappaB2 complex15
GO:0005829
IDA
IBA
TAS
Genome Projectcytosol
GO:0005829
IDA
TAS
Gene Ontologycytosol
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005737
IDA
Gene Ontologycytoplasm16
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005654
TAS
Gene Ontologynucleoplasm
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus16
GO:0035580
IEA
PLAZA Integrative Orthologyspecific granule lumen ENSG00000109320
GO:0005719
IEA
PLAZA Integrative Orthologynuclear euchromatin FBgn0014018
GO:0000228
IEA
PLAZA Integrative Orthologynuclear chromosome FBgn0014018
GO:0012505
IEA
PLAZA Integrative Orthologyendomembrane system ENSG00000109320
GO:0044427
IEA
PLAZA Integrative Orthologychromosomal part FBgn0014018
GO:0034774
IEA
PLAZA Integrative Orthologysecretory granule lumen ENSG00000109320
GO:0000790
IEA
PLAZA Integrative Orthologynuclear chromatin FBgn0014018
GO:0000791
IEA
PLAZA Integrative Orthologyeuchromatin FBgn0014018
GO:0000785
IEA
PLAZA Integrative Orthologychromatin FBgn0014018
GO:0042581
IEA
PLAZA Integrative Orthologyspecific granule ENSG00000109320
GO:0044454
IEA
PLAZA Integrative Orthologynuclear chromosome part FBgn0014018
GO:0043232
IEA
PLAZA Integrative Orthologyintracellular non-membrane-bounded organelle FBgn0014018
GO:0030141
IEA
PLAZA Integrative Orthologysecretory granule ENSG00000109320
GO:0043228
IEA
PLAZA Integrative Orthologynon-membrane-bounded organelle FBgn0014018
GO:0044433
IEA
PLAZA Integrative Orthologycytoplasmic vesicle part ENSG00000109320
GO:0031410
IEA
PLAZA Integrative Orthologycytoplasmic vesicle ENSG00000109320
GO:0099503
IEA
PLAZA Integrative Orthologysecretory vesicle ENSG00000109320
GO:0005576
IEA
PLAZA Integrative Orthologyextracellular region ENSG00000109320
GO:0005694
IEA
PLAZA Integrative Orthologychromosome FBgn0014018
GO:0031983
IEA
PLAZA Integrative Orthologyvesicle lumen ENSG00000109320
GO:0031982
IEA
PLAZA Integrative Orthologyvesicle ENSG00000109320
GO:0097708
IEA
PLAZA Integrative Orthologyintracellular vesicle ENSG00000109320
GO:0060205
IEA
PLAZA Integrative Orthologycytoplasmic vesicle lumen ENSG00000109320
GO:0005739
IEA
PLAZA Integrative Orthologymitochondrion ENSG00000109320

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000451NF-kappa-B/Dorsal
IPR000488Death domain
IPR002110Ankyrin repeat
IPR002909IPT domain
IPR008967p53-like transcription factor, DNA-binding
IPR011029Death-like domain superfamily
IPR011539Rel homology domain (RHD), DNA-binding domain
IPR013783Immunoglobulin-like fold
IPR014756Immunoglobulin E-set
IPR020683Ankyrin repeat-containing domain
IPR030492Rel homology domain, conserved site
IPR032397Rel homology dimerisation domain
IPR033926NFkappaB IPT domain

No MapMan annotations defined for this gene.
KeggID Description
K04469NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
No chloroplast target sequence found.