Gene: ENSG00000073050 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000073050
Transcript Identifier
ENST00000262887
Gene Type
Coding gene
Location
19 : 43543392-43575458 : negative

Family Information

Homologous gene family
HOM02SEM014428
(6 genes in 4 species)
specific family
Orthologous gene family
ORTHO02SEM013275
(4 genes in 4 species)
specific family

Descriptions

gene_descr
X-ray repair complementing defective repair in Chinese hamster cells 1

Identifiers

Type Value
pidENSP00000262887
HGNC12828
UniprotP18887
RefSeq_mRNANM_006297.2

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1905765
IEA
Genome Projectnegative regulation of protection from non-homologous end joining at telomere
GO:0061819
IEA
Genome Projecttelomeric DNA-containing double minutes formation
GO:0042493
IEA
Genome Projectresponse to drug
GO:0021766
IEA
Genome Projecthippocampus development
GO:0010033
IEA
Genome Projectresponse to organic substance
GO:0006303
IEA
Genome Projectdouble-strand break repair via nonhomologous end joining
GO:0006297
TAS
Genome Projectnucleotide-excision repair, DNA gap filling
GO:0006297
TAS
Gene Ontologynucleotide-excision repair, DNA gap filling
GO:0006288
TAS
Genome Projectbase-excision repair, DNA ligation
GO:0006288
TAS
Gene Ontologybase-excision repair, DNA ligation
GO:0006283
TAS
Genome Projecttranscription-coupled nucleotide-excision repair
GO:0006283
TAS
Gene Ontologytranscription-coupled nucleotide-excision repair
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0000724
TAS
Genome Projectdouble-strand break repair via homologous recombination
GO:0000724
TAS
Gene Ontologydouble-strand break repair via homologous recombination
GO:0000012
IEA
Genome Projectsingle strand break repair
GO:1904877
IMP
Gene Ontologypositive regulation of DNA ligase activity1
GO:1990414
IMP
Gene Ontologyreplication-born double-strand break repair via sister chromatid exchange1
GO:0050882
IMP
Gene Ontologyvoluntary musculoskeletal movement1
GO:1903518
IMP, IGI
Gene Ontologypositive regulation of single strand break repair1
GO:0033194
IDA
Gene Ontologyresponse to hydroperoxide1
GO:0010836
IMP
Gene Ontologynegative regulation of protein ADP-ribosylation1
GO:0051336
IEA
PLAZA Integrative Orthologyregulation of hydrolase activity AT1G80420
GO:0035303
IEA
PLAZA Integrative Orthologyregulation of dephosphorylation AT1G80420
GO:0010562
IEA
PLAZA Integrative Orthologypositive regulation of phosphorus metabolic process AT1G80420
GO:0010921
IEA
PLAZA Integrative Orthologyregulation of phosphatase activity AT1G80420
GO:0035306
IEA
PLAZA Integrative Orthologypositive regulation of dephosphorylation AT1G80420
GO:0030154
IEA
PLAZA Integrative Orthologycell differentiation FBgn0026751
GO:0045165
IEA
PLAZA Integrative Orthologycell fate commitment FBgn0026751
GO:0023052
IEA
PLAZA Integrative Orthologysignaling FBgn0026751
GO:0046331
IEA
PLAZA Integrative Orthologylateral inhibition FBgn0026751
GO:0051174
IEA
PLAZA Integrative Orthologyregulation of phosphorus metabolic process AT1G80420
GO:0010922
IEA
PLAZA Integrative Orthologypositive regulation of phosphatase activity AT1G80420
GO:1901968
IEA
PLAZA Integrative Orthologyregulation of polynucleotide 3'-phosphatase activity AT1G80420
GO:1901969
IEA
PLAZA Integrative Orthologypositive regulation of polynucleotide 3'-phosphatase activity AT1G80420
GO:0048869
IEA
PLAZA Integrative Orthologycellular developmental process FBgn0026751
GO:0006796
IEA
PLAZA Integrative Orthologyphosphate-containing compound metabolic process AT1G80420
GO:1902544
IEA
PLAZA Integrative Orthologyregulation of DNA N-glycosylase activity AT1G80420
GO:0006793
IEA
PLAZA Integrative Orthologyphosphorus metabolic process AT1G80420
GO:1902546
IEA
PLAZA Integrative Orthologypositive regulation of DNA N-glycosylase activity AT1G80420
GO:1901971
IEA
PLAZA Integrative Orthologyregulation of DNA-5-methylcytosine glycosylase activity AT1G80420
GO:0007267
IEA
PLAZA Integrative Orthologycell-cell signaling FBgn0026751
GO:1901972
IEA
PLAZA Integrative Orthologypositive regulation of DNA-5-methylcytosine glycosylase activity AT1G80420
GO:0044728
IEA
PLAZA Integrative OrthologyDNA methylation or demethylation AT1G80420
GO:0045937
IEA
PLAZA Integrative Orthologypositive regulation of phosphate metabolic process AT1G80420
GO:0070988
IEA
PLAZA Integrative Orthologydemethylation AT1G80420
GO:0016311
IEA
PLAZA Integrative Orthologydephosphorylation AT1G80420
GO:0035510
IEA
PLAZA Integrative OrthologyDNA dealkylation AT1G80420
GO:0019220
IEA
PLAZA Integrative Orthologyregulation of phosphate metabolic process AT1G80420
GO:0051345
IEA
PLAZA Integrative Orthologypositive regulation of hydrolase activity AT1G80420
GO:0006304
IEA
PLAZA Integrative OrthologyDNA modification AT1G80420
GO:0045168
IEA
PLAZA Integrative Orthologycell-cell signaling involved in cell fate commitment FBgn0026751
GO:0080111
IEA
PLAZA Integrative OrthologyDNA demethylation AT1G80420
GO:0007154
IEA
PLAZA Integrative Orthologycell communication FBgn0026751
GO:0006285
IEA
PLAZA Integrative Orthologybase-excision repair, AP site formation FBgn0026751

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1990599
IEA
Genome Project3' overhang single-stranded DNA endodeoxyribonuclease activity
GO:0019899
IPI
Genome Projectenzyme binding
GO:0019899
IPI
Gene Ontologyenzyme binding2
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
GO:0003909
TAS
Genome ProjectDNA ligase activity
GO:0003909
TAS
Gene OntologyDNA ligase activity
GO:0003684
IEA
Genome Projectdamaged DNA binding
GO:0032356
IMP
Gene Ontologyoxidized DNA binding1
GO:0003690
IEA
PLAZA Integrative Orthologydouble-stranded DNA binding AT1G80420
GO:0010385
IEA
PLAZA Integrative Orthologydouble-stranded methylated DNA binding AT1G80420

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0070522
IEA
Genome ProjectERCC4-ERCC1 complex
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005654
TAS
Gene Ontologynucleoplasm
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus
GO:0000784
IEA
Genome Projectnuclear chromosome, telomeric region
GO:0005730
IDA
Gene Ontologynucleolus1
GO:0000790
IDA
Gene Ontologynuclear chromatin1

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001357BRCT domain
IPR002706DNA-repair protein Xrcc1, N-terminal
IPR008979Galactose-binding-like domain superfamily

No MapMan annotations defined for this gene.
KeggID Description
K10803XRCC1; DNA-repair protein XRCC1
No chloroplast target sequence found.