Gene: ENSG00000071794 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000071794
Transcript Identifier
ENST00000494055
Gene Type
Coding gene
Location
3 : 149032220-149086336 : negative

Family Information

Homologous gene family
HOM02SEM000010
(859 genes in 26 species)
specific family

Descriptions

gene_descr
helicase-like transcription factor

Identifiers

Type Value
pidENSP00000420429
HGNC11099
UniprotQ14527
EMBLAJ418064
EMBLBC044659
EMBLCH471052
EMBLL34673
EMBLS64671
EMBLZ46606

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0045944
IEA
Genome Projectpositive regulation of transcription by RNA polymerase II
GO:0016569
IEA
Genome Projectcovalent chromatin modification
GO:0016567
TAS
Genome Projectprotein ubiquitination
GO:0016567
TAS
Gene Ontologyprotein ubiquitination
GO:0006366
IEA
Genome Projecttranscription by RNA polymerase II
GO:0006355
TAS
Genome Projectregulation of transcription, DNA-templated
GO:0006355
TAS
Gene Ontologyregulation of transcription, DNA-templated1
GO:0006301
IEA
Genome Projectpostreplication repair
GO:0000209
IEA
Genome Projectprotein polyubiquitination
GO:0010605
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule metabolic process SPBC23E6.02
GO:0048869
IEA
PLAZA Integrative Orthologycellular developmental process YOR191W
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction YOR191W
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process AT1G61140
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process AT1G61140
GO:0033036
IEA
PLAZA Integrative Orthologymacromolecule localization YBR114W
GO:1990505
IEA
PLAZA Integrative Orthologymitotic DNA replication maintenance of fidelity SPBC23E6.02
GO:0044265
IEA
PLAZA Integrative Orthologycellular macromolecule catabolic process SPBC23E6.02
GO:0032505
IEA
PLAZA Integrative Orthologyreproduction of a single-celled organism YOR191W
GO:0009605
IEA
PLAZA Integrative Orthologyresponse to external stimulus SPBC23E6.02
GO:0044257
IEA
PLAZA Integrative Orthologycellular protein catabolic process SPBC23E6.02
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development AT1G61140
GO:0009056
IEA
PLAZA Integrative Orthologycatabolic process SPBC23E6.02
GO:0009057
IEA
PLAZA Integrative Orthologymacromolecule catabolic process SPBC23E6.02
GO:0009292
IEA
PLAZA Integrative Orthologygenetic transfer AT5G22750
GO:0009294
IEA
PLAZA Integrative OrthologyDNA mediated transformation AT5G22750
GO:0043161
IEA
PLAZA Integrative Orthologyproteasome-mediated ubiquitin-dependent protein catabolic process SPBC23E6.02
GO:0031668
IEA
PLAZA Integrative Orthologycellular response to extracellular stimulus SPBC23E6.02
GO:0010629
IEA
PLAZA Integrative Orthologynegative regulation of gene expression AT1G50410
GO:0044248
IEA
PLAZA Integrative Orthologycellular catabolic process SPBC23E6.02
GO:0042177
IEA
PLAZA Integrative Orthologynegative regulation of protein catabolic process SPBC23E6.02
GO:0042176
IEA
PLAZA Integrative Orthologyregulation of protein catabolic process SPBC23E6.02
GO:0022607
IEA
PLAZA Integrative Orthologycellular component assembly YLR032W
GO:0009991
IEA
PLAZA Integrative Orthologyresponse to extracellular stimulus SPBC23E6.02
GO:0061136
IEA
PLAZA Integrative Orthologyregulation of proteasomal protein catabolic process SPBC23E6.02
GO:0032259
IEA
PLAZA Integrative Orthologymethylation AT1G50410
GO:0031047
IEA
PLAZA Integrative Orthologygene silencing by RNA AT1G50410
GO:0045165
IEA
PLAZA Integrative Orthologycell fate commitment YOR191W
GO:0006306
IEA
PLAZA Integrative OrthologyDNA methylation AT1G50410
GO:0006305
IEA
PLAZA Integrative OrthologyDNA alkylation AT1G50410
GO:0043414
IEA
PLAZA Integrative Orthologymacromolecule methylation AT1G50410
GO:0006310
IEA
PLAZA Integrative OrthologyDNA recombination SPBC23E6.02
GO:0019725
IEA
PLAZA Integrative Orthologycellular homeostasis YLR032W
GO:0016458
IEA
PLAZA Integrative Orthologygene silencing AT1G50410
GO:0032269
IEA
PLAZA Integrative Orthologynegative regulation of cellular protein metabolic process SPBC23E6.02
GO:0019985
IEA
PLAZA Integrative Orthologytranslesion synthesis YLR032W
GO:0051704
IEA
PLAZA Integrative Orthologymulti-organism process AT5G22750
GO:0032268
IEA
PLAZA Integrative Orthologyregulation of cellular protein metabolic process SPBC23E6.02
GO:2000779
IEA
PLAZA Integrative Orthologyregulation of double-strand break repair YOR191W
GO:1902969
IEA
PLAZA Integrative Orthologymitotic DNA replication SPBC23E6.02
GO:0006302
IEA
PLAZA Integrative Orthologydouble-strand break repair SPBC23E6.02
GO:0006304
IEA
PLAZA Integrative OrthologyDNA modification AT1G50410
GO:0006303
IEA
PLAZA Integrative Orthologydouble-strand break repair via nonhomologous end joining YOR191W
GO:1902298
IEA
PLAZA Integrative Orthologycell cycle DNA replication maintenance of fidelity SPBC23E6.02
GO:2000780
IEA
PLAZA Integrative Orthologynegative regulation of double-strand break repair YOR191W
GO:0051258
IEA
PLAZA Integrative Orthologyprotein polymerization YLR032W
GO:0045934
IEA
PLAZA Integrative Orthologynegative regulation of nucleobase-containing compound metabolic process YOR191W
GO:0043632
IEA
PLAZA Integrative Orthologymodification-dependent macromolecule catabolic process SPBC23E6.02
GO:0048523
IEA
PLAZA Integrative Orthologynegative regulation of cellular process SPBC23E6.02
GO:0006333
IEA
PLAZA Integrative Orthologychromatin assembly or disassembly YOR191W
GO:0044728
IEA
PLAZA Integrative OrthologyDNA methylation or demethylation AT1G50410
GO:0010498
IEA
PLAZA Integrative Orthologyproteasomal protein catabolic process SPBC23E6.02
GO:0051248
IEA
PLAZA Integrative Orthologynegative regulation of protein metabolic process SPBC23E6.02
GO:0071897
IEA
PLAZA Integrative OrthologyDNA biosynthetic process YLR032W
GO:0051246
IEA
PLAZA Integrative Orthologyregulation of protein metabolic process SPBC23E6.02
GO:0007533
IEA
PLAZA Integrative Orthologymating type switching YOR191W
GO:0048519
IEA
PLAZA Integrative Orthologynegative regulation of biological process SPBC23E6.02
GO:0007530
IEA
PLAZA Integrative Orthologysex determination YOR191W
GO:0045003
IEA
PLAZA Integrative Orthologydouble-strand break repair via synthesis-dependent strand annealing AT5G22750
GO:0080135
IEA
PLAZA Integrative Orthologyregulation of cellular response to stress YOR191W
GO:0007531
IEA
PLAZA Integrative Orthologymating type determination YOR191W
GO:0080134
IEA
PLAZA Integrative Orthologyregulation of response to stress YOR191W
GO:0045005
IEA
PLAZA Integrative OrthologyDNA-dependent DNA replication maintenance of fidelity SPBC23E6.02
GO:1903363
IEA
PLAZA Integrative Orthologynegative regulation of cellular protein catabolic process SPBC23E6.02
GO:0033260
IEA
PLAZA Integrative Orthologynuclear DNA replication SPBC23E6.02
GO:1903362
IEA
PLAZA Integrative Orthologyregulation of cellular protein catabolic process SPBC23E6.02
GO:0030154
IEA
PLAZA Integrative Orthologycell differentiation YOR191W
GO:0006508
IEA
PLAZA Integrative Orthologyproteolysis SPBC23E6.02
GO:0006511
IEA
PLAZA Integrative Orthologyubiquitin-dependent protein catabolic process SPBC23E6.02
GO:0007049
IEA
PLAZA Integrative Orthologycell cycle SPBC23E6.02
GO:0044786
IEA
PLAZA Integrative Orthologycell cycle DNA replication SPBC23E6.02
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process YOR191W
GO:1901575
IEA
PLAZA Integrative Orthologyorganic substance catabolic process SPBC23E6.02
GO:0022413
IEA
PLAZA Integrative Orthologyreproductive process in single-celled organism YOR191W
GO:0048229
IEA
PLAZA Integrative Orthologygametophyte development AT1G61140
GO:0030162
IEA
PLAZA Integrative Orthologyregulation of proteolysis SPBC23E6.02
GO:0030163
IEA
PLAZA Integrative Orthologyprotein catabolic process SPBC23E6.02
GO:2000059
IEA
PLAZA Integrative Orthologynegative regulation of ubiquitin-dependent protein catabolic process SPBC23E6.02
GO:0019941
IEA
PLAZA Integrative Orthologymodification-dependent protein catabolic process SPBC23E6.02
GO:2000058
IEA
PLAZA Integrative Orthologyregulation of ubiquitin-dependent protein catabolic process SPBC23E6.02
GO:0048585
IEA
PLAZA Integrative Orthologynegative regulation of response to stimulus YOR191W
GO:0048583
IEA
PLAZA Integrative Orthologyregulation of response to stimulus YOR191W
GO:0045861
IEA
PLAZA Integrative Orthologynegative regulation of proteolysis SPBC23E6.02
GO:1901565
IEA
PLAZA Integrative Orthologyorganonitrogen compound catabolic process SPBC23E6.02
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development AT1G61140
GO:0007154
IEA
PLAZA Integrative Orthologycell communication SPBC23E6.02
GO:2001033
IEA
PLAZA Integrative Orthologynegative regulation of double-strand break repair via nonhomologous end joining YOR191W
GO:2001032
IEA
PLAZA Integrative Orthologyregulation of double-strand break repair via nonhomologous end joining YOR191W
GO:1903051
IEA
PLAZA Integrative Orthologynegative regulation of proteolysis involved in cellular protein catabolic process SPBC23E6.02
GO:1903050
IEA
PLAZA Integrative Orthologyregulation of proteolysis involved in cellular protein catabolic process SPBC23E6.02
GO:0051053
IEA
PLAZA Integrative Orthologynegative regulation of DNA metabolic process YOR191W
GO:0042592
IEA
PLAZA Integrative Orthologyhomeostatic process YLR032W
GO:0051179
IEA
PLAZA Integrative Orthologylocalization YBR114W
GO:1901799
IEA
PLAZA Integrative Orthologynegative regulation of proteasomal protein catabolic process SPBC23E6.02
GO:0044764
IEA
PLAZA Integrative Orthologymulti-organism cellular process AT5G22750
GO:0080188
IEA
PLAZA Integrative OrthologyRNA-directed DNA methylation AT1G50410
GO:0045738
IEA
PLAZA Integrative Orthologynegative regulation of DNA repair YOR191W
GO:2001021
IEA
PLAZA Integrative Orthologynegative regulation of response to DNA damage stimulus YOR191W
GO:2001020
IEA
PLAZA Integrative Orthologyregulation of response to DNA damage stimulus YOR191W
GO:0051603
IEA
PLAZA Integrative Orthologyproteolysis involved in cellular protein catabolic process SPBC23E6.02
GO:0044085
IEA
PLAZA Integrative Orthologycellular component biogenesis YLR032W
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction YOR191W
GO:0051052
IEA
PLAZA Integrative Orthologyregulation of DNA metabolic process YOR191W
GO:0051172
IEA
PLAZA Integrative Orthologynegative regulation of nitrogen compound metabolic process SPBC23E6.02
GO:0036297
IEA
PLAZA Integrative Orthologyinterstrand cross-link repair AT5G22750
GO:1903047
IEA
PLAZA Integrative Orthologymitotic cell cycle process SPBC23E6.02
GO:0031324
IEA
PLAZA Integrative Orthologynegative regulation of cellular metabolic process SPBC23E6.02
GO:0031329
IEA
PLAZA Integrative Orthologyregulation of cellular catabolic process SPBC23E6.02
GO:0000720
IEA
PLAZA Integrative Orthologypyrimidine dimer repair by nucleotide-excision repair SPCC330.01c
GO:0000724
IEA
PLAZA Integrative Orthologydouble-strand break repair via homologous recombination SPBC23E6.02
GO:0000725
IEA
PLAZA Integrative Orthologyrecombinational repair SPBC23E6.02
GO:0000726
IEA
PLAZA Integrative Orthologynon-recombinational repair YOR191W
GO:0043933
IEA
PLAZA Integrative Orthologyprotein-containing complex subunit organization YLR032W
GO:0070987
IEA
PLAZA Integrative Orthologyerror-free translesion synthesis YLR032W
GO:0010994
IEA
PLAZA Integrative Orthologyfree ubiquitin chain polymerization YLR032W
GO:0010992
IEA
PLAZA Integrative Orthologyubiquitin recycling YLR032W
GO:0031330
IEA
PLAZA Integrative Orthologynegative regulation of cellular catabolic process SPBC23E6.02
GO:0000278
IEA
PLAZA Integrative Orthologymitotic cell cycle SPBC23E6.02
GO:0009894
IEA
PLAZA Integrative Orthologyregulation of catabolic process SPBC23E6.02
GO:0009895
IEA
PLAZA Integrative Orthologynegative regulation of catabolic process SPBC23E6.02
GO:0042276
IEA
PLAZA Integrative Orthologyerror-prone translesion synthesis YLR032W
GO:0042275
IEA
PLAZA Integrative Orthologyerror-free postreplication DNA repair YLR032W
GO:0006261
IEA
PLAZA Integrative OrthologyDNA-dependent DNA replication SPBC23E6.02
GO:0000715
IEA
PLAZA Integrative Orthologynucleotide-excision repair, DNA damage recognition YBR114W
GO:0006260
IEA
PLAZA Integrative OrthologyDNA replication SPBC23E6.02
GO:0009892
IEA
PLAZA Integrative Orthologynegative regulation of metabolic process SPBC23E6.02
GO:0032435
IEA
PLAZA Integrative Orthologynegative regulation of proteasomal ubiquitin-dependent protein catabolic process SPBC23E6.02
GO:0034613
IEA
PLAZA Integrative Orthologycellular protein localization YBR114W
GO:0032434
IEA
PLAZA Integrative Orthologyregulation of proteasomal ubiquitin-dependent protein catabolic process SPBC23E6.02
GO:0065003
IEA
PLAZA Integrative Orthologyprotein-containing complex assembly YLR032W
GO:0006290
IEA
PLAZA Integrative Orthologypyrimidine dimer repair SPCC330.01c
GO:0065008
IEA
PLAZA Integrative Orthologyregulation of biological quality YLR032W
GO:0034622
IEA
PLAZA Integrative Orthologycellular protein-containing complex assembly YLR032W
GO:0071496
IEA
PLAZA Integrative Orthologycellular response to external stimulus SPBC23E6.02
GO:0042262
IEA
PLAZA Integrative OrthologyDNA protection SPBC23E6.02
GO:0051641
IEA
PLAZA Integrative Orthologycellular localization YBR114W
GO:0000731
IEA
PLAZA Integrative OrthologyDNA synthesis involved in DNA repair YLR032W
GO:0009553
IEA
PLAZA Integrative Orthologyembryo sac development AT1G61140
GO:0006289
IEA
PLAZA Integrative Orthologynucleotide-excision repair SPCC330.01c
GO:0008104
IEA
PLAZA Integrative Orthologyprotein localization YBR114W
GO:0022402
IEA
PLAZA Integrative Orthologycell cycle process SPBC23E6.02
GO:0006282
IEA
PLAZA Integrative Orthologyregulation of DNA repair YOR191W
GO:0070727
IEA
PLAZA Integrative Orthologycellular macromolecule localization YBR114W

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0061630
EXP
Genome Projectubiquitin protein ligase activity
GO:0061630
EXP
Gene Ontologyubiquitin protein ligase activity2 3 4 5 6
GO:0031625
IDA
Genome Projectubiquitin protein ligase binding
GO:0031625
IDA
Gene Ontologyubiquitin protein ligase binding7
GO:0016887
IEA
Genome ProjectATPase activity
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding2 3 8 9
GO:0004386
IEA
Genome Projecthelicase activity
GO:0003723
IDA
Genome ProjectRNA binding
GO:0003723
Gene OntologyRNA binding10
GO:0003677
TAS
Genome ProjectDNA binding
GO:0003677
TAS
Gene OntologyDNA binding1
GO:0000978
IEA
Genome ProjectRNA polymerase II proximal promoter sequence-specific DNA binding
GO:0008094
IEA
PLAZA Integrative OrthologyDNA-dependent ATPase activity YBR114W
GO:0032183
IEA
PLAZA Integrative OrthologySUMO binding YOR191W
GO:0032182
IEA
PLAZA Integrative Orthologyubiquitin-like protein binding YOR191W
GO:0042623
IEA
PLAZA Integrative OrthologyATPase activity, coupled SPBC23E6.02
GO:0140097
IEA
PLAZA Integrative Orthologycatalytic activity, acting on DNA YLR032W
GO:0009378
IEA
PLAZA Integrative Orthologyfour-way junction helicase activity YLR032W
GO:0000217
IEA
PLAZA Integrative OrthologyDNA secondary structure binding YLR032W
GO:0140083
IEA
PLAZA Integrative Orthologyprotein-DNA unloading ATPase activity SPBC23E6.02
GO:0000400
IEA
PLAZA Integrative Orthologyfour-way junction DNA binding YLR032W
GO:0000403
IEA
PLAZA Integrative OrthologyY-form DNA binding YLR032W
GO:0003678
IEA
PLAZA Integrative OrthologyDNA helicase activity YLR032W
GO:0003684
IEA
PLAZA Integrative Orthologydamaged DNA binding YBR114W

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016020
IDA
Genome Projectmembrane
GO:0016020
Gene Ontologymembrane11
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005730
IEA
Genome Projectnucleolus
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005654
IDA
TAS
Gene Ontologynucleoplasm
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus
GO:0000113
IEA
PLAZA Integrative Orthologynucleotide-excision repair factor 4 complex YBR114W
GO:1902494
IEA
PLAZA Integrative Orthologycatalytic complex YBR114W
GO:0032991
IEA
PLAZA Integrative Orthologyprotein-containing complex SPCC330.01c
GO:0000151
IEA
PLAZA Integrative Orthologyubiquitin ligase complex YBR114W
GO:0009526
IEA
PLAZA Integrative Orthologyplastid envelope AT5G43530
GO:0005829
IEA
PLAZA Integrative Orthologycytosol SPAC17A2.12
GO:0009507
IEA
PLAZA Integrative Orthologychloroplast AT5G43530
GO:0098687
IEA
PLAZA Integrative Orthologychromosomal region YLR032W
GO:0031967
IEA
PLAZA Integrative Orthologyorganelle envelope AT5G43530
GO:0009941
IEA
PLAZA Integrative Orthologychloroplast envelope AT5G43530
GO:0031975
IEA
PLAZA Integrative Orthologyenvelope AT5G43530
GO:0000794
IEA
PLAZA Integrative Orthologycondensed nuclear chromosome YOR191W
GO:0005694
IEA
PLAZA Integrative Orthologychromosome SPAC17A2.12
GO:1990391
IEA
PLAZA Integrative OrthologyDNA repair complex SPCC330.01c
GO:0000228
IEA
PLAZA Integrative Orthologynuclear chromosome YLR032W
GO:0000109
IEA
PLAZA Integrative Orthologynucleotide-excision repair complex SPCC330.01c
GO:0090734
IEA
PLAZA Integrative Orthologysite of DNA damage SPAC17A2.12
GO:1990234
IEA
PLAZA Integrative Orthologytransferase complex YBR114W
GO:0044427
IEA
PLAZA Integrative Orthologychromosomal part SPAC17A2.12
GO:0035861
IEA
PLAZA Integrative Orthologysite of double-strand break SPAC17A2.12
GO:0000790
IEA
PLAZA Integrative Orthologynuclear chromatin YLR032W
GO:0000793
IEA
PLAZA Integrative Orthologycondensed chromosome YOR191W
GO:0000785
IEA
PLAZA Integrative Orthologychromatin YLR032W
GO:0000780
IEA
PLAZA Integrative Orthologycondensed nuclear chromosome, centromeric region YOR191W
GO:0000781
IEA
PLAZA Integrative Orthologychromosome, telomeric region YLR032W
GO:0000775
IEA
PLAZA Integrative Orthologychromosome, centromeric region YOR191W
GO:0000776
IEA
PLAZA Integrative Orthologykinetochore YOR191W
GO:0000777
IEA
PLAZA Integrative Orthologycondensed chromosome kinetochore YOR191W
GO:0000778
IEA
PLAZA Integrative Orthologycondensed nuclear chromosome kinetochore YOR191W
GO:0000779
IEA
PLAZA Integrative Orthologycondensed chromosome, centromeric region YOR191W
GO:0005739
IEA
PLAZA Integrative Orthologymitochondrion YOR191W
GO:0009536
IEA
PLAZA Integrative Orthologyplastid AT5G43530
GO:0044454
IEA
PLAZA Integrative Orthologynuclear chromosome part YLR032W
GO:0031461
IEA
PLAZA Integrative Orthologycullin-RING ubiquitin ligase complex YBR114W
GO:0031463
IEA
PLAZA Integrative OrthologyCul3-RING ubiquitin ligase complex YBR114W
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part SPAC17A2.12
GO:0044435
IEA
PLAZA Integrative Orthologyplastid part AT5G43530
GO:0044434
IEA
PLAZA Integrative Orthologychloroplast part AT5G43530

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000330SNF2-related, N-terminal domain
IPR001650Helicase, C-terminal
IPR001841Zinc finger, RING-type
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR014001Helicase superfamily 1/2, ATP-binding domain
IPR014905HIRAN domain
IPR017907Zinc finger, RING-type, conserved site
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.
KeggID Description
K15711SMARCA3, HLTF; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:3.6.4.- 2.3.2.27]
No chloroplast target sequence found.