Gene: ENSG00000071537 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000071537
Transcript Identifier
ENST00000336735
Gene Type
Coding gene
Location
14 : 81476972-81533744 : negative

Family Information

Homologous gene family
HOM02SEM003386
(23 genes in 15 species)
specific family

Descriptions

gene_descr
sel-1 suppressor of lin-12-like (C. elegans)

Identifiers

Type Value
pidENSP00000337053
HGNC10717
UniprotQ9UBV2
RefSeq_mRNANM_005065.5
EMBLAB020335
EMBLAB024763
EMBLAF052059
EMBLAF157516
EMBLAF198631
EMBLAF198632
EMBLAF198633
EMBLAF198634
EMBLAF198635
EMBLAF198636
EMBLAF198637
EMBLAF198638
EMBLAF198639
EMBLAF198640
EMBLAF198641
EMBLAF198642
EMBLAF198643
EMBLAF198644
EMBLAF198645
EMBLAF198646
EMBLAF198647
EMBLAY358651

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1904380
TAS
Genome Projectendoplasmic reticulum mannose trimming
GO:1904380
TAS
Gene Ontologyendoplasmic reticulum mannose trimming
GO:0055085
TAS
Genome Projecttransmembrane transport
GO:0055085
TAS
Gene Ontologytransmembrane transport
GO:0050821
TAS
Genome Projectprotein stabilization
GO:0050821
TAS
Gene Ontologyprotein stabilization1
GO:0036503
IMP
ISS
Genome ProjectERAD pathway
GO:0036503
IMP
ISS
Gene OntologyERAD pathway2 3
GO:0030970
IMP
Genome Projectretrograde protein transport, ER to cytosol
GO:0030970
IMP
Gene Ontologyretrograde protein transport, ER to cytosol4
GO:0030433
TAS
Genome Projectubiquitin-dependent ERAD pathway
GO:0030433
TAS
Gene Ontologyubiquitin-dependent ERAD pathway5
GO:0009306
ISS
Genome Projectprotein secretion
GO:0009306
ISS
Gene Ontologyprotein secretion
GO:0007219
IEA
Genome ProjectNotch signaling pathway
GO:0006641
ISS
Genome Projecttriglyceride metabolic process
GO:0006641
ISS
Gene Ontologytriglyceride metabolic process
GO:0010646
IEA
PLAZA Integrative Orthologyregulation of cell communication WBGene00004759
GO:0010648
IEA
PLAZA Integrative Orthologynegative regulation of cell communication WBGene00004759
GO:0023051
IEA
PLAZA Integrative Orthologyregulation of signaling WBGene00004759
GO:0023057
IEA
PLAZA Integrative Orthologynegative regulation of signaling WBGene00004759
GO:0006972
IEA
PLAZA Integrative Orthologyhyperosmotic response AT1G18260
GO:0009966
IEA
PLAZA Integrative Orthologyregulation of signal transduction WBGene00004759
GO:0048523
IEA
PLAZA Integrative Orthologynegative regulation of cellular process WBGene00004759
GO:0006970
IEA
PLAZA Integrative Orthologyresponse to osmotic stress AT1G18260
GO:0008593
IEA
PLAZA Integrative Orthologyregulation of Notch signaling pathway WBGene00004759
GO:0048585
IEA
PLAZA Integrative Orthologynegative regulation of response to stimulus WBGene00004759
GO:0009968
IEA
PLAZA Integrative Orthologynegative regulation of signal transduction WBGene00004759
GO:0009628
IEA
PLAZA Integrative Orthologyresponse to abiotic stimulus AT1G18260
GO:0048583
IEA
PLAZA Integrative Orthologyregulation of response to stimulus WBGene00004759
GO:0045746
IEA
PLAZA Integrative Orthologynegative regulation of Notch signaling pathway WBGene00004759
GO:0048519
IEA
PLAZA Integrative Orthologynegative regulation of biological process WBGene00004759
GO:0009651
IEA
PLAZA Integrative Orthologyresponse to salt stress AT1G18260
GO:0042538
IEA
PLAZA Integrative Orthologyhyperosmotic salinity response AT1G18260

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding3 6 7 8 9 10 11
GO:0016740
IEA
PLAZA Integrative Orthologytransferase activity YLR207W
GO:0004842
IEA
PLAZA Integrative Orthologyubiquitin-protein transferase activity YLR207W
GO:0140096
IEA
PLAZA Integrative Orthologycatalytic activity, acting on a protein YLR207W
GO:0019787
IEA
PLAZA Integrative Orthologyubiquitin-like protein transferase activity YLR207W
GO:0003824
IEA
PLAZA Integrative Orthologycatalytic activity YLR207W

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0044322
IEA
Genome Projectendoplasmic reticulum quality control compartment
GO:0036513
IDA
Genome ProjectDerlin-1 retrotranslocation complex
GO:0036513
IDA
Gene OntologyDerlin-1 retrotranslocation complex2
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0005789
TAS
Genome Projectendoplasmic reticulum membrane
GO:0005789
TAS
Gene Ontologyendoplasmic reticulum membrane
GO:0005783
IDA
Genome Projectendoplasmic reticulum
GO:0005783
IDA
Gene Ontologyendoplasmic reticulum3
GO:0000839
IMP
Genome ProjectHrd1p ubiquitin ligase ERAD-L complex
GO:0000839
IMP
Gene OntologyHrd1p ubiquitin ligase ERAD-L complex3
GO:0000836
TAS
Genome ProjectHrd1p ubiquitin ligase complex
GO:0000836
TAS
Gene OntologyHrd1p ubiquitin ligase complex1 2
GO:0031982
IEA
PLAZA Integrative Orthologyvesicle WBGene00004759
GO:0070013
IEA
PLAZA Integrative Orthologyintracellular organelle lumen YLR207W
GO:0043233
IEA
PLAZA Integrative Orthologyorganelle lumen YLR207W
GO:0097708
IEA
PLAZA Integrative Orthologyintracellular vesicle WBGene00004759
GO:0031974
IEA
PLAZA Integrative Orthologymembrane-enclosed lumen YLR207W
GO:0031410
IEA
PLAZA Integrative Orthologycytoplasmic vesicle WBGene00004759
GO:0005788
IEA
PLAZA Integrative Orthologyendoplasmic reticulum lumen YLR207W
GO:0034099
IEA
PLAZA Integrative Orthologyluminal surveillance complex YLR207W
GO:0000838
IEA
PLAZA Integrative OrthologyHrd1p ubiquitin ligase ERAD-M complex YLR207W

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000562Fibronectin type II domain
IPR006597Sel1-like repeat
IPR013806Kringle-like fold

No MapMan annotations defined for this gene.
KeggID Description
K14026SEL1, SEL1L; SEL1 protein
No chloroplast target sequence found.