Gene: ENSG00000047249 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000047249
Transcript Identifier
ENST00000396774
Gene Type
Coding gene
Location
8 : 53715964-53841690 : negative

Family Information

Homologous gene family
HOM02SEM000864
(53 genes in 25 species)
specific family
Orthologous gene family
ORTHO02SEM000929
(52 genes in 25 species)
specific family

Descriptions

gene_descr
ATPase, H transporting, lysosomal 50/57kDa, V1 subunit H

Identifiers

Type Value
pidENSP00000379995
HGNC18303
UniprotQ9UI12
UniprotA0A024R7U9
RefSeq_mRNANM_213620.2
EMBLCH471068

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0090383
TAS
Genome Projectphagosome acidification
GO:0050790
IEA
Genome Projectregulation of catalytic activity
GO:0050690
TAS
Genome Projectregulation of defense response to virus by virus
GO:0050690
TAS
Gene Ontologyregulation of defense response to virus by virus
GO:0034220
TAS
Genome Projection transmembrane transport
GO:0034220
TAS
Gene Ontologyion transmembrane transport
GO:0033572
TAS
Genome Projecttransferrin transport
GO:0033572
TAS
Gene Ontologytransferrin transport
GO:0016241
NAS
Genome Projectregulation of macroautophagy
GO:0016241
NAS
Gene Ontologyregulation of macroautophagy1
GO:0016032
IEA
Genome Projectviral process
GO:0015991
NAS
Genome ProjectATP hydrolysis coupled proton transport
GO:0015991
NAS
Gene OntologyATP hydrolysis coupled proton transport2
GO:0008286
TAS
Genome Projectinsulin receptor signaling pathway
GO:0008286
TAS
Gene Ontologyinsulin receptor signaling pathway
GO:0007035
IBA
NAS
Genome Projectvacuolar acidification
GO:0007035
NAS
Gene Ontologyvacuolar acidification2
GO:0006897
IDA
Genome Projectendocytosis
GO:0006897
IDA
Gene Ontologyendocytosis3
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process FBgn0027779
GO:0015931
IEA
PLAZA Integrative Orthologynucleobase-containing compound transport FBgn0027779
GO:0033227
IEA
PLAZA Integrative OrthologydsRNA transport FBgn0027779
GO:0050657
IEA
PLAZA Integrative Orthologynucleic acid transport FBgn0027779
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process FBgn0027779
GO:0050658
IEA
PLAZA Integrative OrthologyRNA transport FBgn0027779
GO:0010259
IEA
PLAZA Integrative Orthologymulticellular organism aging FBgn0027779
GO:0051236
IEA
PLAZA Integrative Orthologyestablishment of RNA localization FBgn0027779
GO:0006403
IEA
PLAZA Integrative OrthologyRNA localization FBgn0027779
GO:0007568
IEA
PLAZA Integrative Orthologyaging FBgn0027779
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development FBgn0027779
GO:0008340
IEA
PLAZA Integrative Orthologydetermination of adult lifespan FBgn0027779
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development FBgn0027779

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016887
NAS
Genome ProjectATPase activity
GO:0016887
NAS
Gene OntologyATPase activity2
GO:0046961
IBA
Genome Projectproton-transporting ATPase activity, rotational mechanism
GO:0030234
NAS
Genome Projectenzyme regulator activity
GO:0030234
NAS
Gene Ontologyenzyme regulator activity2
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding3 4 5 6

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0070062
Gene Ontologyextracellular exosome7 8
GO:0005886
TAS
Genome Projectplasma membrane
GO:0005886
TAS
Gene Ontologyplasma membrane
GO:0005829
TAS
Genome Projectcytosol
GO:0005829
TAS
Gene Ontologycytosol
GO:0005765
IDA
Genome Projectlysosomal membrane
GO:0005765
Gene Ontologylysosomal membrane9
GO:0000221
IBA
NAS
Genome Projectvacuolar proton-transporting V-type ATPase, V1 domain
GO:0000221
NAS
Gene Ontologyvacuolar proton-transporting V-type ATPase, V1 domain2
GO:0012505
IEA
PLAZA Integrative Orthologyendomembrane system AT3G42050
GO:0098797
IEA
PLAZA Integrative Orthologyplasma membrane protein complex FBgn0027779
GO:0009507
IEA
PLAZA Integrative Orthologychloroplast AT3G42050
GO:0044459
IEA
PLAZA Integrative Orthologyplasma membrane part FBgn0027779
GO:0000322
IEA
PLAZA Integrative Orthologystorage vacuole YPR036W
GO:0009536
IEA
PLAZA Integrative Orthologyplastid AT3G42050
GO:0000324
IEA
PLAZA Integrative Orthologyfungal-type vacuole YPR036W
GO:0000325
IEA
PLAZA Integrative Orthologyplant-type vacuole AT3G42050
GO:0005794
IEA
PLAZA Integrative OrthologyGolgi apparatus AT3G42050
GO:0000329
IEA
PLAZA Integrative Orthologyfungal-type vacuole membrane YPR036W
GO:0033181
IEA
PLAZA Integrative Orthologyplasma membrane proton-transporting V-type ATPase complex FBgn0027779

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR004908ATPase, V1 complex, subunit H
IPR011987ATPase, V1 complex, subunit H, C-terminal
IPR011989Armadillo-like helical
IPR016024Armadillo-type fold

No MapMan annotations defined for this gene.
KeggID Description
K02144ATPeV1H; V-type H+-transporting ATPase subunit H
No chloroplast target sequence found.