Gene: ENSG00000025039 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000025039
Transcript Identifier
ENST00000369415
Gene Type
Coding gene
Location
6 : 89368056-89411993 : negative

Family Information

Homologous gene family
HOM02SEM002468
(28 genes in 22 species)
specific family
Orthologous gene family
ORTHO02SEM002764
(27 genes in 22 species)
specific family

Descriptions

gene_descr
Ras-related GTP binding D

Identifiers

Type Value
pidENSP00000358423
HGNC19903
UniprotQ9NQL2
RefSeq_mRNANM_021244.4
EMBLAF272036
EMBLAK289799
EMBLAL137502
EMBLAL138717
EMBLBC003088
EMBLCH471051

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1990253
IMP
Genome Projectcellular response to leucine starvation
GO:1990253
IMP
Gene Ontologycellular response to leucine starvation1
GO:1904263
IMP
Genome Projectpositive regulation of TORC1 signaling
GO:1904263
IMP
Gene Ontologypositive regulation of TORC1 signaling1
GO:0071233
IMP
Genome Projectcellular response to leucine
GO:0071233
IMP
Gene Ontologycellular response to leucine1
GO:0071230
ISS
Genome Projectcellular response to amino acid stimulus
GO:0071230
ISS
Gene Ontologycellular response to amino acid stimulus
GO:0034613
ISS
Genome Projectcellular protein localization
GO:0034613
ISS
Gene Ontologycellular protein localization
GO:0032008
NAS
Genome Projectpositive regulation of TOR signaling
GO:0032008
NAS
Gene Ontologypositive regulation of TOR signaling2
GO:0016241
TAS
Genome Projectregulation of macroautophagy
GO:0016241
TAS
Gene Ontologyregulation of macroautophagy
GO:0007050
TAS
Genome Projectcell cycle arrest
GO:0007050
TAS
Gene Ontologycell cycle arrest
GO:0010604
IEA
PLAZA Integrative Orthologypositive regulation of macromolecule metabolic process YGR163W
GO:0044271
IEA
PLAZA Integrative Orthologycellular nitrogen compound biosynthetic process YGR163W
GO:1903508
IEA
PLAZA Integrative Orthologypositive regulation of nucleic acid-templated transcription YGR163W
GO:0006357
IEA
PLAZA Integrative Orthologyregulation of transcription by RNA polymerase II YGR163W
GO:0006995
IEA
PLAZA Integrative Orthologycellular response to nitrogen starvation SPCC777.05
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization WBGene00012497
GO:0007568
IEA
PLAZA Integrative Orthologyaging WBGene00012497
GO:0006355
IEA
PLAZA Integrative Orthologyregulation of transcription, DNA-templated YGR163W
GO:1901576
IEA
PLAZA Integrative Orthologyorganic substance biosynthetic process YGR163W
GO:0006351
IEA
PLAZA Integrative Orthologytranscription, DNA-templated YGR163W
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process WBGene00012497
GO:0034645
IEA
PLAZA Integrative Orthologycellular macromolecule biosynthetic process YGR163W
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process WBGene00012497
GO:0034641
IEA
PLAZA Integrative Orthologycellular nitrogen compound metabolic process YGR163W
GO:0010557
IEA
PLAZA Integrative Orthologypositive regulation of macromolecule biosynthetic process YGR163W
GO:0010556
IEA
PLAZA Integrative Orthologyregulation of macromolecule biosynthetic process YGR163W
GO:0048585
IEA
PLAZA Integrative Orthologynegative regulation of response to stimulus SPCC777.05
GO:0044260
IEA
PLAZA Integrative Orthologycellular macromolecule metabolic process YGR163W
GO:0009968
IEA
PLAZA Integrative Orthologynegative regulation of signal transduction SPCC777.05
GO:0051345
IEA
PLAZA Integrative Orthologypositive regulation of hydrolase activity YGR163W
GO:0043170
IEA
PLAZA Integrative Orthologymacromolecule metabolic process YGR163W
GO:1903506
IEA
PLAZA Integrative Orthologyregulation of nucleic acid-templated transcription YGR163W
GO:0009058
IEA
PLAZA Integrative Orthologybiosynthetic process YGR163W
GO:0009059
IEA
PLAZA Integrative Orthologymacromolecule biosynthetic process YGR163W
GO:1902532
IEA
PLAZA Integrative Orthologynegative regulation of intracellular signal transduction SPCC777.05
GO:0043562
IEA
PLAZA Integrative Orthologycellular response to nitrogen levels SPCC777.05
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development WBGene00012497
GO:0033043
IEA
PLAZA Integrative Orthologyregulation of organelle organization WBGene00012497
GO:0007033
IEA
PLAZA Integrative Orthologyvacuole organization WBGene00012497
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development WBGene00012497
GO:0051336
IEA
PLAZA Integrative Orthologyregulation of hydrolase activity YGR163W
GO:0019438
IEA
PLAZA Integrative Orthologyaromatic compound biosynthetic process YGR163W
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis WBGene00012497
GO:0034654
IEA
PLAZA Integrative Orthologynucleobase-containing compound biosynthetic process YGR163W
GO:0010467
IEA
PLAZA Integrative Orthologygene expression YGR163W
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization WBGene00012497
GO:0072657
IEA
PLAZA Integrative Orthologyprotein localization to membrane YGR163W
GO:0010468
IEA
PLAZA Integrative Orthologyregulation of gene expression YGR163W
GO:0010507
IEA
PLAZA Integrative Orthologynegative regulation of autophagy YGR163W
GO:0010628
IEA
PLAZA Integrative Orthologypositive regulation of gene expression YGR163W
GO:0006807
IEA
PLAZA Integrative Orthologynitrogen compound metabolic process YGR163W
GO:0044093
IEA
PLAZA Integrative Orthologypositive regulation of molecular function YGR163W
GO:0009889
IEA
PLAZA Integrative Orthologyregulation of biosynthetic process YGR163W
GO:0006139
IEA
PLAZA Integrative Orthologynucleobase-containing compound metabolic process YGR163W
GO:0044249
IEA
PLAZA Integrative Orthologycellular biosynthetic process YGR163W
GO:1904262
IEA
PLAZA Integrative Orthologynegative regulation of TORC1 signaling SPCC777.05
GO:2001141
IEA
PLAZA Integrative Orthologyregulation of RNA biosynthetic process YGR163W
GO:0090304
IEA
PLAZA Integrative Orthologynucleic acid metabolic process YGR163W
GO:0032007
IEA
PLAZA Integrative Orthologynegative regulation of TOR signaling SPCC777.05
GO:0072665
IEA
PLAZA Integrative Orthologyprotein localization to vacuole YGR163W
GO:0044088
IEA
PLAZA Integrative Orthologyregulation of vacuole organization WBGene00012497
GO:0044087
IEA
PLAZA Integrative Orthologyregulation of cellular component biogenesis WBGene00012497
GO:0044085
IEA
PLAZA Integrative Orthologycellular component biogenesis WBGene00012497
GO:0043547
IEA
PLAZA Integrative Orthologypositive regulation of GTPase activity YGR163W
GO:0044238
IEA
PLAZA Integrative Orthologyprimary metabolic process YGR163W
GO:1902115
IEA
PLAZA Integrative Orthologyregulation of organelle assembly WBGene00012497
GO:0051171
IEA
PLAZA Integrative Orthologyregulation of nitrogen compound metabolic process YGR163W
GO:0006366
IEA
PLAZA Integrative Orthologytranscription by RNA polymerase II YGR163W
GO:0051173
IEA
PLAZA Integrative Orthologypositive regulation of nitrogen compound metabolic process YGR163W
GO:0022607
IEA
PLAZA Integrative Orthologycellular component assembly WBGene00012497
GO:0070925
IEA
PLAZA Integrative Orthologyorganelle assembly WBGene00012497
GO:0031324
IEA
PLAZA Integrative Orthologynegative regulation of cellular metabolic process YGR163W
GO:0080090
IEA
PLAZA Integrative Orthologyregulation of primary metabolic process YGR163W
GO:0071704
IEA
PLAZA Integrative Orthologyorganic substance metabolic process YGR163W
GO:0031326
IEA
PLAZA Integrative Orthologyregulation of cellular biosynthetic process YGR163W
GO:0031325
IEA
PLAZA Integrative Orthologypositive regulation of cellular metabolic process YGR163W
GO:0032774
IEA
PLAZA Integrative OrthologyRNA biosynthetic process YGR163W
GO:2000785
IEA
PLAZA Integrative Orthologyregulation of autophagosome assembly WBGene00012497
GO:0010648
IEA
PLAZA Integrative Orthologynegative regulation of cell communication SPCC777.05
GO:0031328
IEA
PLAZA Integrative Orthologypositive regulation of cellular biosynthetic process YGR163W
GO:0060255
IEA
PLAZA Integrative Orthologyregulation of macromolecule metabolic process YGR163W
GO:0016237
IEA
PLAZA Integrative Orthologylysosomal microautophagy YGR163W
GO:0031330
IEA
PLAZA Integrative Orthologynegative regulation of cellular catabolic process YGR163W
GO:0018130
IEA
PLAZA Integrative Orthologyheterocycle biosynthetic process YGR163W
GO:0016070
IEA
PLAZA Integrative OrthologyRNA metabolic process YGR163W
GO:0046483
IEA
PLAZA Integrative Orthologyheterocycle metabolic process YGR163W
GO:0000045
IEA
PLAZA Integrative Orthologyautophagosome assembly WBGene00012497
GO:0045944
IEA
PLAZA Integrative Orthologypositive regulation of transcription by RNA polymerase II YGR163W
GO:0009895
IEA
PLAZA Integrative Orthologynegative regulation of catabolic process YGR163W
GO:0009891
IEA
PLAZA Integrative Orthologypositive regulation of biosynthetic process YGR163W
GO:0009892
IEA
PLAZA Integrative Orthologynegative regulation of metabolic process YGR163W
GO:1901362
IEA
PLAZA Integrative Orthologyorganic cyclic compound biosynthetic process YGR163W
GO:0009893
IEA
PLAZA Integrative Orthologypositive regulation of metabolic process YGR163W
GO:1901360
IEA
PLAZA Integrative Orthologyorganic cyclic compound metabolic process YGR163W
GO:0019219
IEA
PLAZA Integrative Orthologyregulation of nucleobase-containing compound metabolic process YGR163W
GO:0033365
IEA
PLAZA Integrative Orthologyprotein localization to organelle YGR163W
GO:0097659
IEA
PLAZA Integrative Orthologynucleic acid-templated transcription YGR163W
GO:0043087
IEA
PLAZA Integrative Orthologyregulation of GTPase activity YGR163W
GO:0051252
IEA
PLAZA Integrative Orthologyregulation of RNA metabolic process YGR163W
GO:0043085
IEA
PLAZA Integrative Orthologypositive regulation of catalytic activity YGR163W
GO:0051254
IEA
PLAZA Integrative Orthologypositive regulation of RNA metabolic process YGR163W
GO:0023057
IEA
PLAZA Integrative Orthologynegative regulation of signaling SPCC777.05
GO:0006725
IEA
PLAZA Integrative Orthologycellular aromatic compound metabolic process YGR163W
GO:0065009
IEA
PLAZA Integrative Orthologyregulation of molecular function YGR163W
GO:1903778
IEA
PLAZA Integrative Orthologyprotein localization to vacuolar membrane YGR163W
GO:1905037
IEA
PLAZA Integrative Orthologyautophagosome organization WBGene00012497
GO:0007264
IEA
PLAZA Integrative Orthologysmall GTPase mediated signal transduction ENSG00000116954
GO:0045935
IEA
PLAZA Integrative Orthologypositive regulation of nucleobase-containing compound metabolic process YGR163W
GO:1902680
IEA
PLAZA Integrative Orthologypositive regulation of RNA biosynthetic process YGR163W
GO:0051128
IEA
PLAZA Integrative Orthologyregulation of cellular component organization WBGene00012497
GO:2000112
IEA
PLAZA Integrative Orthologyregulation of cellular macromolecule biosynthetic process YGR163W
GO:0010259
IEA
PLAZA Integrative Orthologymulticellular organism aging WBGene00012497
GO:0050790
IEA
PLAZA Integrative Orthologyregulation of catalytic activity YGR163W
GO:0045893
IEA
PLAZA Integrative Orthologypositive regulation of transcription, DNA-templated YGR163W
GO:0008340
IEA
PLAZA Integrative Orthologydetermination of adult lifespan WBGene00012497

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0051020
IPI
Genome ProjectGTPase binding
GO:0051020
IPI
Gene OntologyGTPase binding1
GO:0046982
IPI, IMP
Genome Projectprotein heterodimerization activity
GO:0046982
IPI, IMP
Gene Ontologyprotein heterodimerization activity1 3
GO:0019003
IMP
Genome ProjectGDP binding
GO:0019003
IMP
Gene OntologyGDP binding1
GO:0005525
IMP
Genome ProjectGTP binding
GO:0005525
IMP
Gene OntologyGTP binding1
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 2 3 4 5 6 7
GO:0003924
IMP
Genome ProjectGTPase activity
GO:0003924
IMP
Gene OntologyGTPase activity1

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005829
TAS
Genome Projectcytosol
GO:0005829
TAS
Gene Ontologycytosol
GO:0005813
IDA
Genome Projectcentrosome
GO:0005813
IDA
Gene Ontologycentrosome
GO:0005764
IDA
Genome Projectlysosome
GO:0005764
IDA
Gene Ontologylysosome2
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005737
IDA
Gene Ontologycytoplasm3
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005654
IDA
Gene Ontologynucleoplasm
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus3
GO:0098805
IEA
PLAZA Integrative Orthologywhole membrane SPCC777.05
GO:0012505
IEA
PLAZA Integrative Orthologyendomembrane system YGR163W
GO:0016020
IEA
PLAZA Integrative Orthologymembrane SPCC777.05
GO:0044427
IEA
PLAZA Integrative Orthologychromosomal part YGR163W
GO:0031090
IEA
PLAZA Integrative Orthologyorganelle membrane SPCC777.05
GO:0044425
IEA
PLAZA Integrative Orthologymembrane part YGR163W
GO:0097708
IEA
PLAZA Integrative Orthologyintracellular vesicle YGR163W
GO:0031410
IEA
PLAZA Integrative Orthologycytoplasmic vesicle YGR163W
GO:0005768
IEA
PLAZA Integrative Orthologyendosome YGR163W
GO:0005774
IEA
PLAZA Integrative Orthologyvacuolar membrane SPCC777.05
GO:0005770
IEA
PLAZA Integrative Orthologylate endosome YGR163W
GO:0032991
IEA
PLAZA Integrative Orthologyprotein-containing complex SPCC777.05
GO:0000790
IEA
PLAZA Integrative Orthologynuclear chromatin YGR163W
GO:0000785
IEA
PLAZA Integrative Orthologychromatin YGR163W
GO:0010008
IEA
PLAZA Integrative Orthologyendosome membrane YGR163W
GO:0000322
IEA
PLAZA Integrative Orthologystorage vacuole SPCC777.05
GO:0000324
IEA
PLAZA Integrative Orthologyfungal-type vacuole SPCC777.05
GO:0000329
IEA
PLAZA Integrative Orthologyfungal-type vacuole membrane SPCC777.05
GO:0034448
IEA
PLAZA Integrative OrthologyEGO complex YGR163W
GO:0098796
IEA
PLAZA Integrative Orthologymembrane protein complex YGR163W
GO:0005694
IEA
PLAZA Integrative Orthologychromosome YGR163W
GO:0044454
IEA
PLAZA Integrative Orthologynuclear chromosome part YGR163W
GO:0031982
IEA
PLAZA Integrative Orthologyvesicle YGR163W
GO:0098588
IEA
PLAZA Integrative Orthologybounding membrane of organelle SPCC777.05
GO:0031902
IEA
PLAZA Integrative Orthologylate endosome membrane YGR163W
GO:0000228
IEA
PLAZA Integrative Orthologynuclear chromosome YGR163W
GO:0044440
IEA
PLAZA Integrative Orthologyendosomal part YGR163W
GO:0098852
IEA
PLAZA Integrative Orthologylytic vacuole membrane SPCC777.05
GO:0044437
IEA
PLAZA Integrative Orthologyvacuolar part SPCC777.05
GO:1990131
IEA
PLAZA Integrative OrthologyGtr1-Gtr2 GTPase complex SPCC777.05
GO:0044433
IEA
PLAZA Integrative Orthologycytoplasmic vesicle part YGR163W

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR006762Gtr1/RagA G protein
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.
KeggID Description
K16186RRAGC_D; Ras-related GTP-binding protein C/D
No chloroplast target sequence found.