Gene: ENSG00000014123 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000014123
Transcript Identifier
ENST00000369278
Gene Type
Coding gene
Location
6 : 96521874-96553503 : positive

Family Information

Homologous gene family
HOM02SEM009210
(10 genes in 10 species)
specific family

Descriptions

gene_descr
UFM1-specific ligase 1

Identifiers

Type Value
pidENSP00000358283
HGNC23039
UniprotO94874
RefSeq_mRNANM_015323.4
EMBLAB018319
EMBLAK295934
EMBLAL132776
EMBLAL590404
EMBLBC015377
EMBLBC028608
EMBLBC036379
EMBLCH471051

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1990592
IDA
Genome Projectprotein K69-linked ufmylation
GO:1990592
IDA
Gene Ontologyprotein K69-linked ufmylation1
GO:1902065
IEA
Genome Projectresponse to L-glutamate
GO:0071569
IDA, IMP
Genome Projectprotein ufmylation
GO:0071569
IDA, IMP
Gene Ontologyprotein ufmylation2 3
GO:0060252
IEA
Genome Projectpositive regulation of glial cell proliferation
GO:0043066
IEA
Genome Projectnegative regulation of apoptotic process
GO:0034976
IDA
Genome Projectresponse to endoplasmic reticulum stress
GO:0034976
IDA
Gene Ontologyresponse to endoplasmic reticulum stress3
GO:0033146
IDA
Genome Projectregulation of intracellular estrogen receptor signaling pathway
GO:0033146
IDA
Gene Ontologyregulation of intracellular estrogen receptor signaling pathway1
GO:0032880
IMP
Genome Projectregulation of protein localization
GO:0032880
IMP
Gene Ontologyregulation of protein localization4
GO:0032434
IMP
Genome Projectregulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032434
IMP
Gene Ontologyregulation of proteasomal ubiquitin-dependent protein catabolic process5
GO:0032088
IMP
Genome Projectnegative regulation of NF-kappaB transcription factor activity
GO:0032088
IMP
Gene Ontologynegative regulation of NF-kappaB transcription factor activity5 6
GO:0031397
IDA
Genome Projectnegative regulation of protein ubiquitination
GO:0031397
IDA
Gene Ontologynegative regulation of protein ubiquitination6
GO:0008284
IMP
Genome Projectpositive regulation of cell proliferation
GO:0008284
IMP
Gene Ontologypositive regulation of cell proliferation4
GO:0001649
IDA
Genome Projectosteoblast differentiation
GO:0001649
Gene Ontologyosteoblast differentiation7

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0071568
IDA
Genome ProjectUFM1 transferase activity
GO:0071568
IDA
Gene OntologyUFM1 transferase activity2
GO:0016874
IEA
Genome Projectligase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 2 5 6

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0043005
IEA
Genome Projectneuron projection
GO:0016020
IDA
Genome Projectmembrane
GO:0016020
Gene Ontologymembrane7
GO:0005829
IEA
Genome Projectcytosol
GO:0005789
IDA
Genome Projectendoplasmic reticulum membrane
GO:0005789
IDA
Gene Ontologyendoplasmic reticulum membrane4
GO:0005783
IDA
Genome Projectendoplasmic reticulum
GO:0005783
IDA
Gene Ontologyendoplasmic reticulum2 4
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005737
IDA
Gene Ontologycytoplasm6
GO:0032991
IDA
Gene Ontologyprotein-containing complex4

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR018611E3 UFM1-protein ligase 1

No MapMan annotations defined for this gene.
No Kegg annotations defined for this gene.
No chloroplast target sequence found.