Gene: ENSG00000004975 (Homo sapiens)

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Gene Identifier
ENSG00000004975
Transcript Identifier
ENST00000005340
Gene Type
Coding gene
Location
17 : 7225865-7234262 : negative

Family Information

Homologous gene family
HOM02SEM011119
(8 genes in 3 species)
specific family
Orthologous gene family
ORTHO02SEM011896
(5 genes in 3 species)
specific family

Descriptions

gene_descr
dishevelled segment polarity protein 2

Identifiers

Type Value
pidENSP00000005340
HGNC3086
UniprotO14641
RefSeq_mRNANM_004422.2
EMBLCHEMBL1255125
EMBLAF006012
EMBLBC014844
EMBLBT009822
EMBLCH471108

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1904886
TAS
Genome Projectbeta-catenin destruction complex disassembly
GO:1904886
TAS
Gene Ontologybeta-catenin destruction complex disassembly
GO:0090263
IEA
Genome Projectpositive regulation of canonical Wnt signaling pathway
GO:0090179
IBA
Genome Projectplanar cell polarity pathway involved in neural tube closure
GO:0090103
IEA
Genome Projectcochlea morphogenesis
GO:0090090
TAS
Genome Projectnegative regulation of canonical Wnt signaling pathway
GO:0090090
TAS
Gene Ontologynegative regulation of canonical Wnt signaling pathway
GO:0061098
IEA
Genome Projectpositive regulation of protein tyrosine kinase activity
GO:0061024
TAS
Genome Projectmembrane organization
GO:0061024
TAS
Gene Ontologymembrane organization
GO:0060071
IDA
TAS, NAS
Genome ProjectWnt signaling pathway, planar cell polarity pathway
GO:0060071
IDA
TAS, NAS
Gene OntologyWnt signaling pathway, planar cell polarity pathway1 2
GO:0060070
IDA
Genome Projectcanonical Wnt signaling pathway
GO:0060070
IDA
TAS
Gene Ontologycanonical Wnt signaling pathway3 4
GO:0051259
IEA
Genome Projectprotein complex oligomerization
GO:0051091
IDA
Genome Projectpositive regulation of DNA-binding transcription factor activity
GO:0051091
IDA
Gene Ontologypositive regulation of DNA-binding transcription factor activity3
GO:0045893
IDA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045893
IDA
Gene Ontologypositive regulation of transcription, DNA-templated1 3
GO:0044340
IDA
Genome Projectcanonical Wnt signaling pathway involved in regulation of cell proliferation
GO:0044340
IDA
Gene Ontologycanonical Wnt signaling pathway involved in regulation of cell proliferation5
GO:0043547
IEA
Genome Projectpositive regulation of GTPase activity
GO:0043507
IDA, IMP
Genome Projectpositive regulation of JUN kinase activity
GO:0043507
IDA, IMP
Gene Ontologypositive regulation of JUN kinase activity3 6
GO:0035567
IMP
Genome Projectnon-canonical Wnt signaling pathway
GO:0035567
IMP
TAS
Gene Ontologynon-canonical Wnt signaling pathway4 6
GO:0035329
TAS
Genome Projecthippo signaling
GO:0035329
TAS
Gene Ontologyhippo signaling
GO:0034613
IEA
Genome Projectcellular protein localization
GO:0022007
IEA
Genome Projectconvergent extension involved in neural plate elongation
GO:0016055
IGI
Genome ProjectWnt signaling pathway
GO:0007507
ISS
Genome Projectheart development
GO:0007507
ISS
Gene Ontologyheart development
GO:0007379
ISS
Genome Projectsegment specification
GO:0007379
ISS
Gene Ontologysegment specification
GO:0006366
IDA
Genome Projecttranscription by RNA polymerase II
GO:0006366
IDA
Gene Ontologytranscription by RNA polymerase II7
GO:0003151
ISS
Genome Projectoutflow tract morphogenesis
GO:0003151
ISS
Gene Ontologyoutflow tract morphogenesis
GO:0001934
IMP
Genome Projectpositive regulation of protein phosphorylation
GO:0001934
IMP
Gene Ontologypositive regulation of protein phosphorylation8
GO:0001843
ISS
Genome Projectneural tube closure
GO:0001843
ISS
Gene Ontologyneural tube closure
GO:0048072
IEA
PLAZA Integrative Orthologycompound eye pigmentation FBgn0000499
GO:0048073
IEA
PLAZA Integrative Orthologyregulation of eye pigmentation FBgn0000499
GO:0031400
IEA
PLAZA Integrative Orthologynegative regulation of protein modification process ENSG00000107404
GO:0032970
IEA
PLAZA Integrative Orthologyregulation of actin filament-based process FBgn0000499
GO:0050821
IEA
PLAZA Integrative Orthologyprotein stabilization ENSG00000107404
GO:0048070
IEA
PLAZA Integrative Orthologyregulation of developmental pigmentation FBgn0000499
GO:0097435
IEA
PLAZA Integrative Orthologysupramolecular fiber organization FBgn0000499
GO:0010605
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule metabolic process ENSG00000107404
GO:0008406
IEA
PLAZA Integrative Orthologygonad development FBgn0000499
GO:0031647
IEA
PLAZA Integrative Orthologyregulation of protein stability ENSG00000107404
GO:0051234
IEA
PLAZA Integrative Orthologyestablishment of localization WBGene00001101
GO:0048076
IEA
PLAZA Integrative Orthologyregulation of compound eye pigmentation FBgn0000499
GO:0008407
IEA
PLAZA Integrative Orthologychaeta morphogenesis FBgn0000499
GO:0048870
IEA
PLAZA Integrative Orthologycell motility FBgn0000499
GO:0000132
IEA
PLAZA Integrative Orthologyestablishment of mitotic spindle orientation FBgn0000499
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction FBgn0000499
GO:0048749
IEA
PLAZA Integrative Orthologycompound eye development FBgn0000499
GO:0007560
IEA
PLAZA Integrative Orthologyimaginal disc morphogenesis FBgn0000499
GO:0007444
IEA
PLAZA Integrative Orthologyimaginal disc development FBgn0000499
GO:0061387
IEA
PLAZA Integrative Orthologyregulation of extent of cell growth FBgn0000499
GO:0044703
IEA
PLAZA Integrative Orthologymulti-organism reproductive process FBgn0000499
GO:0051348
IEA
PLAZA Integrative Orthologynegative regulation of transferase activity ENSG00000107404
GO:0035218
IEA
PLAZA Integrative Orthologyleg disc development FBgn0000499
GO:0048069
IEA
PLAZA Integrative Orthologyeye pigmentation FBgn0000499
GO:0045596
IEA
PLAZA Integrative Orthologynegative regulation of cell differentiation FBgn0000499
GO:0044265
IEA
PLAZA Integrative Orthologycellular macromolecule catabolic process ENSG00000107404
GO:0051100
IEA
PLAZA Integrative Orthologynegative regulation of binding ENSG00000107404
GO:0048863
IEA
PLAZA Integrative Orthologystem cell differentiation FBgn0000499
GO:0007548
IEA
PLAZA Integrative Orthologysex differentiation FBgn0000499
GO:0009605
IEA
PLAZA Integrative Orthologyresponse to external stimulus FBgn0000499
GO:0032504
IEA
PLAZA Integrative Orthologymulticellular organism reproduction FBgn0000499
GO:0048066
IEA
PLAZA Integrative Orthologydevelopmental pigmentation FBgn0000499
GO:0007435
IEA
PLAZA Integrative Orthologysalivary gland morphogenesis FBgn0000499
GO:0048736
IEA
PLAZA Integrative Orthologyappendage development FBgn0000499
GO:0099054
IEA
PLAZA Integrative Orthologypresynapse assembly ENSG00000107404
GO:0048737
IEA
PLAZA Integrative Orthologyimaginal disc-derived appendage development FBgn0000499
GO:0006469
IEA
PLAZA Integrative Orthologynegative regulation of protein kinase activity ENSG00000107404
GO:0048732
IEA
PLAZA Integrative Orthologygland development FBgn0000499
GO:0007552
IEA
PLAZA Integrative Orthologymetamorphosis FBgn0000499
GO:0007431
IEA
PLAZA Integrative Orthologysalivary gland development FBgn0000499
GO:0044257
IEA
PLAZA Integrative Orthologycellular protein catabolic process ENSG00000107404
GO:0099172
IEA
PLAZA Integrative Orthologypresynapse organization ENSG00000107404
GO:0033043
IEA
PLAZA Integrative Orthologyregulation of organelle organization WBGene00001101
GO:0009056
IEA
PLAZA Integrative Orthologycatabolic process ENSG00000107404
GO:0060069
IEA
PLAZA Integrative OrthologyWnt signaling pathway, regulating spindle positioning WBGene00001101
GO:0009057
IEA
PLAZA Integrative Orthologymacromolecule catabolic process ENSG00000107404
GO:0035220
IEA
PLAZA Integrative Orthologywing disc development FBgn0000499
GO:0016049
IEA
PLAZA Integrative Orthologycell growth FBgn0000499
GO:0050921
IEA
PLAZA Integrative Orthologypositive regulation of chemotaxis FBgn0000499
GO:0120031
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection assembly FBgn0000499
GO:0050920
IEA
PLAZA Integrative Orthologyregulation of chemotaxis FBgn0000499
GO:0035107
IEA
PLAZA Integrative Orthologyappendage morphogenesis FBgn0000499
GO:0006928
IEA
PLAZA Integrative Orthologymovement of cell or subcellular component FBgn0000499
GO:0048730
IEA
PLAZA Integrative Orthologyepidermis morphogenesis FBgn0000499
GO:0007219
IEA
PLAZA Integrative OrthologyNotch signaling pathway FBgn0000499
GO:0032879
IEA
PLAZA Integrative Orthologyregulation of localization ENSG00000107404
GO:0097581
IEA
PLAZA Integrative Orthologylamellipodium organization FBgn0000499
GO:0043161
IEA
PLAZA Integrative Orthologyproteasome-mediated ubiquitin-dependent protein catabolic process ENSG00000107404
GO:0007346
IEA
PLAZA Integrative Orthologyregulation of mitotic cell cycle WBGene00001101
GO:0090381
IEA
PLAZA Integrative Orthologyregulation of heart induction FBgn0000499
GO:0042067
IEA
PLAZA Integrative Orthologyestablishment of ommatidial planar polarity FBgn0000499
GO:0044248
IEA
PLAZA Integrative Orthologycellular catabolic process ENSG00000107404
GO:0046545
IEA
PLAZA Integrative Orthologydevelopment of primary female sexual characteristics FBgn0000499
GO:0009886
IEA
PLAZA Integrative Orthologypost-embryonic animal morphogenesis FBgn0000499
GO:0050808
IEA
PLAZA Integrative Orthologysynapse organization ENSG00000107404
GO:0009880
IEA
PLAZA Integrative Orthologyembryonic pattern specification FBgn0000499
GO:0032880
IEA
PLAZA Integrative Orthologyregulation of protein localization ENSG00000107404
GO:0048608
IEA
PLAZA Integrative Orthologyreproductive structure development FBgn0000499
GO:0048609
IEA
PLAZA Integrative Orthologymulticellular organismal reproductive process FBgn0000499
GO:0061245
IEA
PLAZA Integrative Orthologyestablishment or maintenance of bipolar cell polarity FBgn0000499
GO:0035114
IEA
PLAZA Integrative Orthologyimaginal disc-derived appendage morphogenesis FBgn0000499
GO:0032886
IEA
PLAZA Integrative Orthologyregulation of microtubule-based process WBGene00001101
GO:0046660
IEA
PLAZA Integrative Orthologyfemale sex differentiation FBgn0000499
GO:1902903
IEA
PLAZA Integrative Orthologyregulation of supramolecular fiber organization FBgn0000499
GO:0043393
IEA
PLAZA Integrative Orthologyregulation of protein binding ENSG00000107404
GO:0009997
IEA
PLAZA Integrative Orthologynegative regulation of cardioblast cell fate specification FBgn0000499
GO:0032091
IEA
PLAZA Integrative Orthologynegative regulation of protein binding ENSG00000107404
GO:0090130
IEA
PLAZA Integrative Orthologytissue migration FBgn0000499
GO:0110110
IEA
PLAZA Integrative Orthologypositive regulation of animal organ morphogenesis FBgn0000499
GO:0090132
IEA
PLAZA Integrative Orthologyepithelium migration FBgn0000499
GO:0008544
IEA
PLAZA Integrative Orthologyepidermis development FBgn0000499
GO:0042176
IEA
PLAZA Integrative Orthologyregulation of protein catabolic process ENSG00000107404
GO:0009996
IEA
PLAZA Integrative Orthologynegative regulation of cell fate specification FBgn0000499
GO:1902474
IEA
PLAZA Integrative Orthologypositive regulation of protein localization to synapse ENSG00000107404
GO:0035120
IEA
PLAZA Integrative Orthologypost-embryonic appendage morphogenesis FBgn0000499
GO:1902473
IEA
PLAZA Integrative Orthologyregulation of protein localization to synapse ENSG00000107404
GO:0050919
IEA
PLAZA Integrative Orthologynegative chemotaxis FBgn0000499
GO:0061136
IEA
PLAZA Integrative Orthologyregulation of proteasomal protein catabolic process ENSG00000107404
GO:0045165
IEA
PLAZA Integrative Orthologycell fate commitment FBgn0000499
GO:0010002
IEA
PLAZA Integrative Orthologycardioblast differentiation FBgn0000499
GO:0048675
IEA
PLAZA Integrative Orthologyaxon extension FBgn0000499
GO:0001654
IEA
PLAZA Integrative Orthologyeye development FBgn0000499
GO:0030516
IEA
PLAZA Integrative Orthologyregulation of axon extension FBgn0000499
GO:1903827
IEA
PLAZA Integrative Orthologyregulation of cellular protein localization ENSG00000107404
GO:0042326
IEA
PLAZA Integrative Orthologynegative regulation of phosphorylation ENSG00000107404
GO:0042686
IEA
PLAZA Integrative Orthologyregulation of cardioblast cell fate specification FBgn0000499
GO:0042685
IEA
PLAZA Integrative Orthologycardioblast cell fate specification FBgn0000499
GO:0090163
IEA
PLAZA Integrative Orthologyestablishment of epithelial cell planar polarity FBgn0000499
GO:0048667
IEA
PLAZA Integrative Orthologycell morphogenesis involved in neuron differentiation FBgn0000499
GO:0090162
IEA
PLAZA Integrative Orthologyestablishment of epithelial cell polarity FBgn0000499
GO:0031290
IEA
PLAZA Integrative Orthologyretinal ganglion cell axon guidance FBgn0000499
GO:0042684
IEA
PLAZA Integrative Orthologycardioblast cell fate commitment FBgn0000499
GO:0032269
IEA
PLAZA Integrative Orthologynegative regulation of cellular protein metabolic process ENSG00000107404
GO:0016477
IEA
PLAZA Integrative Orthologycell migration FBgn0000499
GO:0016476
IEA
PLAZA Integrative Orthologyregulation of embryonic cell shape FBgn0000499
GO:0051704
IEA
PLAZA Integrative Orthologymulti-organism process FBgn0000499
GO:0035418
IEA
PLAZA Integrative Orthologyprotein localization to synapse ENSG00000107404
GO:0040017
IEA
PLAZA Integrative Orthologypositive regulation of locomotion FBgn0000499
GO:0003156
IEA
PLAZA Integrative Orthologyregulation of animal organ formation FBgn0000499
GO:0002066
IEA
PLAZA Integrative Orthologycolumnar/cuboidal epithelial cell development FBgn0000499
GO:0051270
IEA
PLAZA Integrative Orthologyregulation of cellular component movement FBgn0000499
GO:0002065
IEA
PLAZA Integrative Orthologycolumnar/cuboidal epithelial cell differentiation FBgn0000499
GO:0002064
IEA
PLAZA Integrative Orthologyepithelial cell development FBgn0000499
GO:0051272
IEA
PLAZA Integrative Orthologypositive regulation of cellular component movement FBgn0000499
GO:1905207
IEA
PLAZA Integrative Orthologyregulation of cardiocyte differentiation FBgn0000499
GO:1905208
IEA
PLAZA Integrative Orthologynegative regulation of cardiocyte differentiation FBgn0000499
GO:0040011
IEA
PLAZA Integrative Orthologylocomotion FBgn0000499
GO:1902850
IEA
PLAZA Integrative Orthologymicrotubule cytoskeleton organization involved in mitosis WBGene00001101
GO:0008045
IEA
PLAZA Integrative Orthologymotor neuron axon guidance FBgn0000499
GO:0040012
IEA
PLAZA Integrative Orthologyregulation of locomotion FBgn0000499
GO:0060541
IEA
PLAZA Integrative Orthologyrespiratory system development FBgn0000499
GO:0016348
IEA
PLAZA Integrative Orthologyimaginal disc-derived leg joint morphogenesis FBgn0000499
GO:0051017
IEA
PLAZA Integrative Orthologyactin filament bundle assembly FBgn0000499
GO:0033365
IEA
PLAZA Integrative Orthologyprotein localization to organelle ENSG00000107404
GO:0051493
IEA
PLAZA Integrative Orthologyregulation of cytoskeleton organization WBGene00001101
GO:0001558
IEA
PLAZA Integrative Orthologyregulation of cell growth FBgn0000499
GO:0035309
IEA
PLAZA Integrative Orthologywing and notum subfield formation FBgn0000499
GO:1990138
IEA
PLAZA Integrative Orthologyneuron projection extension FBgn0000499
GO:0032956
IEA
PLAZA Integrative Orthologyregulation of actin cytoskeleton organization FBgn0000499
GO:0043086
IEA
PLAZA Integrative Orthologynegative regulation of catalytic activity ENSG00000107404
GO:0007416
IEA
PLAZA Integrative Orthologysynapse assembly ENSG00000107404
GO:0040007
IEA
PLAZA Integrative Orthologygrowth FBgn0000499
GO:0007424
IEA
PLAZA Integrative Orthologyopen tracheal system development FBgn0000499
GO:0040008
IEA
PLAZA Integrative Orthologyregulation of growth FBgn0000499
GO:0043632
IEA
PLAZA Integrative Orthologymodification-dependent macromolecule catabolic process ENSG00000107404
GO:0000226
IEA
PLAZA Integrative Orthologymicrotubule cytoskeleton organization WBGene00001101
GO:0048645
IEA
PLAZA Integrative Orthologyanimal organ formation FBgn0000499
GO:0090066
IEA
PLAZA Integrative Orthologyregulation of anatomical structure size FBgn0000499
GO:0045137
IEA
PLAZA Integrative Orthologydevelopment of primary sexual characteristics FBgn0000499
GO:0061162
IEA
PLAZA Integrative Orthologyestablishment of monopolar cell polarity FBgn0000499
GO:0000904
IEA
PLAZA Integrative Orthologycell morphogenesis involved in differentiation FBgn0000499
GO:0040001
IEA
PLAZA Integrative Orthologyestablishment of mitotic spindle localization WBGene00001101
GO:0045936
IEA
PLAZA Integrative Orthologynegative regulation of phosphate metabolic process ENSG00000107404
GO:0035315
IEA
PLAZA Integrative Orthologyhair cell differentiation FBgn0000499
GO:0010498
IEA
PLAZA Integrative Orthologyproteasomal protein catabolic process ENSG00000107404
GO:0051248
IEA
PLAZA Integrative Orthologynegative regulation of protein metabolic process ENSG00000107404
GO:0035317
IEA
PLAZA Integrative Orthologyimaginal disc-derived wing hair organization FBgn0000499
GO:0035316
IEA
PLAZA Integrative Orthologynon-sensory hair organization FBgn0000499
GO:0051241
IEA
PLAZA Integrative Orthologynegative regulation of multicellular organismal process FBgn0000499
GO:0007409
IEA
PLAZA Integrative Orthologyaxonogenesis FBgn0000499
GO:0001667
IEA
PLAZA Integrative Orthologyameboidal-type cell migration FBgn0000499
GO:0009826
IEA
PLAZA Integrative Orthologyunidimensional cell growth FBgn0000499
GO:0030307
IEA
PLAZA Integrative Orthologypositive regulation of cell growth FBgn0000499
GO:0048880
IEA
PLAZA Integrative Orthologysensory system development FBgn0000499
GO:0097485
IEA
PLAZA Integrative Orthologyneuron projection guidance FBgn0000499
GO:0048638
IEA
PLAZA Integrative Orthologyregulation of developmental growth FBgn0000499
GO:0048639
IEA
PLAZA Integrative Orthologypositive regulation of developmental growth FBgn0000499
GO:0007411
IEA
PLAZA Integrative Orthologyaxon guidance FBgn0000499
GO:1903364
IEA
PLAZA Integrative Orthologypositive regulation of cellular protein catabolic process ENSG00000107404
GO:0042659
IEA
PLAZA Integrative Orthologyregulation of cell fate specification FBgn0000499
GO:0045927
IEA
PLAZA Integrative Orthologypositive regulation of growth FBgn0000499
GO:1903362
IEA
PLAZA Integrative Orthologyregulation of cellular protein catabolic process ENSG00000107404
GO:0010564
IEA
PLAZA Integrative Orthologyregulation of cell cycle process WBGene00001101
GO:0030036
IEA
PLAZA Integrative Orthologyactin cytoskeleton organization FBgn0000499
GO:0010563
IEA
PLAZA Integrative Orthologynegative regulation of phosphorus metabolic process ENSG00000107404
GO:0031128
IEA
PLAZA Integrative Orthologydevelopmental induction FBgn0000499
GO:0030032
IEA
PLAZA Integrative Orthologylamellipodium assembly FBgn0000499
GO:0001737
IEA
PLAZA Integrative Orthologyestablishment of imaginal disc-derived wing hair orientation FBgn0000499
GO:0048477
IEA
PLAZA Integrative Orthologyoogenesis FBgn0000499
GO:0006508
IEA
PLAZA Integrative Orthologyproteolysis ENSG00000107404
GO:0048592
IEA
PLAZA Integrative Orthologyeye morphogenesis FBgn0000499
GO:0022412
IEA
PLAZA Integrative Orthologycellular process involved in reproduction in multicellular organism FBgn0000499
GO:0006511
IEA
PLAZA Integrative Orthologyubiquitin-dependent protein catabolic process ENSG00000107404
GO:1902669
IEA
PLAZA Integrative Orthologypositive regulation of axon guidance FBgn0000499
GO:0007049
IEA
PLAZA Integrative Orthologycell cycle WBGene00001101
GO:0046847
IEA
PLAZA Integrative Orthologyfilopodium assembly FBgn0000499
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization WBGene00001101
GO:0022416
IEA
PLAZA Integrative Orthologychaeta development FBgn0000499
GO:0048589
IEA
PLAZA Integrative Orthologydevelopmental growth FBgn0000499
GO:0048106
IEA
PLAZA Integrative Orthologyestablishment of thoracic bristle planar orientation FBgn0000499
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process FBgn0000499
GO:1902667
IEA
PLAZA Integrative Orthologyregulation of axon guidance FBgn0000499
GO:0007163
IEA
PLAZA Integrative Orthologyestablishment or maintenance of cell polarity FBgn0000499
GO:1901575
IEA
PLAZA Integrative Orthologyorganic substance catabolic process ENSG00000107404
GO:0030162
IEA
PLAZA Integrative Orthologyregulation of proteolysis ENSG00000107404
GO:0030163
IEA
PLAZA Integrative Orthologyprotein catabolic process ENSG00000107404
GO:0007281
IEA
PLAZA Integrative Orthologygerm cell development FBgn0000499
GO:0035051
IEA
PLAZA Integrative Orthologycardiocyte differentiation FBgn0000499
GO:0019941
IEA
PLAZA Integrative Orthologymodification-dependent protein catabolic process ENSG00000107404
GO:0033673
IEA
PLAZA Integrative Orthologynegative regulation of kinase activity ENSG00000107404
GO:0032101
IEA
PLAZA Integrative Orthologyregulation of response to external stimulus FBgn0000499
GO:0032103
IEA
PLAZA Integrative Orthologypositive regulation of response to external stimulus FBgn0000499
GO:2000058
IEA
PLAZA Integrative Orthologyregulation of ubiquitin-dependent protein catabolic process ENSG00000107404
GO:2000737
IEA
PLAZA Integrative Orthologynegative regulation of stem cell differentiation FBgn0000499
GO:0045198
IEA
PLAZA Integrative Orthologyestablishment of epithelial cell apical/basal polarity FBgn0000499
GO:2000736
IEA
PLAZA Integrative Orthologyregulation of stem cell differentiation FBgn0000499
GO:0045197
IEA
PLAZA Integrative Orthologyestablishment or maintenance of epithelial cell apical/basal polarity FBgn0000499
GO:0050770
IEA
PLAZA Integrative Orthologyregulation of axonogenesis FBgn0000499
GO:0048588
IEA
PLAZA Integrative Orthologydevelopmental cell growth FBgn0000499
GO:0048104
IEA
PLAZA Integrative Orthologyestablishment of body hair or bristle planar orientation FBgn0000499
GO:0050772
IEA
PLAZA Integrative Orthologypositive regulation of axonogenesis FBgn0000499
GO:0061316
IEA
PLAZA Integrative Orthologycanonical Wnt signaling pathway involved in heart development FBgn0000499
GO:0045746
IEA
PLAZA Integrative Orthologynegative regulation of Notch signaling pathway FBgn0000499
GO:0045862
IEA
PLAZA Integrative Orthologypositive regulation of proteolysis ENSG00000107404
GO:0007276
IEA
PLAZA Integrative Orthologygamete generation FBgn0000499
GO:1901565
IEA
PLAZA Integrative Orthologyorganonitrogen compound catabolic process ENSG00000107404
GO:0008361
IEA
PLAZA Integrative Orthologyregulation of cell size FBgn0000499
GO:0007394
IEA
PLAZA Integrative Orthologydorsal closure, elongation of leading edge cells FBgn0000499
GO:0032231
IEA
PLAZA Integrative Orthologyregulation of actin filament bundle assembly FBgn0000499
GO:1901320
IEA
PLAZA Integrative Orthologynegative regulation of heart induction FBgn0000499
GO:0007392
IEA
PLAZA Integrative Orthologyinitiation of dorsal closure FBgn0000499
GO:0061311
IEA
PLAZA Integrative Orthologycell surface receptor signaling pathway involved in heart development FBgn0000499
GO:2000060
IEA
PLAZA Integrative Orthologypositive regulation of ubiquitin-dependent protein catabolic process ENSG00000107404
GO:0008360
IEA
PLAZA Integrative Orthologyregulation of cell shape FBgn0000499
GO:0007391
IEA
PLAZA Integrative Orthologydorsal closure FBgn0000499
GO:0060341
IEA
PLAZA Integrative Orthologyregulation of cellular localization ENSG00000107404
GO:0044092
IEA
PLAZA Integrative Orthologynegative regulation of molecular function ENSG00000107404
GO:0016201
IEA
PLAZA Integrative Orthologysynaptic target inhibition FBgn0000499
GO:0019953
IEA
PLAZA Integrative Orthologysexual reproduction FBgn0000499
GO:1903050
IEA
PLAZA Integrative Orthologyregulation of proteolysis involved in cellular protein catabolic process ENSG00000107404
GO:2000044
IEA
PLAZA Integrative Orthologynegative regulation of cardiac cell fate specification FBgn0000499
GO:0001759
IEA
PLAZA Integrative Orthologyorgan induction FBgn0000499
GO:0030859
IEA
PLAZA Integrative Orthologypolarized epithelial cell differentiation FBgn0000499
GO:0001754
IEA
PLAZA Integrative Orthologyeye photoreceptor cell differentiation FBgn0000499
GO:0009913
IEA
PLAZA Integrative Orthologyepidermal cell differentiation FBgn0000499
GO:0001751
IEA
PLAZA Integrative Orthologycompound eye photoreceptor cell differentiation FBgn0000499
GO:0030855
IEA
PLAZA Integrative Orthologyepithelial cell differentiation FBgn0000499
GO:0008039
IEA
PLAZA Integrative Orthologysynaptic target recognition FBgn0000499
GO:0008037
IEA
PLAZA Integrative Orthologycell recognition FBgn0000499
GO:0042221
IEA
PLAZA Integrative Orthologyresponse to chemical FBgn0000499
GO:0045732
IEA
PLAZA Integrative Orthologypositive regulation of protein catabolic process ENSG00000107404
GO:0048569
IEA
PLAZA Integrative Orthologypost-embryonic animal organ development FBgn0000499
GO:0008038
IEA
PLAZA Integrative Orthologyneuron recognition FBgn0000499
GO:0019827
IEA
PLAZA Integrative Orthologystem cell population maintenance FBgn0000499
GO:1903052
IEA
PLAZA Integrative Orthologypositive regulation of proteolysis involved in cellular protein catabolic process ENSG00000107404
GO:0010454
IEA
PLAZA Integrative Orthologynegative regulation of cell fate commitment FBgn0000499
GO:0051603
IEA
PLAZA Integrative Orthologyproteolysis involved in cellular protein catabolic process ENSG00000107404
GO:0010453
IEA
PLAZA Integrative Orthologyregulation of cell fate commitment FBgn0000499
GO:0051726
IEA
PLAZA Integrative Orthologyregulation of cell cycle WBGene00001101
GO:0048563
IEA
PLAZA Integrative Orthologypost-embryonic animal organ morphogenesis FBgn0000499
GO:0044087
IEA
PLAZA Integrative Orthologyregulation of cellular component biogenesis FBgn0000499
GO:0001745
IEA
PLAZA Integrative Orthologycompound eye morphogenesis FBgn0000499
GO:0003129
IEA
PLAZA Integrative Orthologyheart induction FBgn0000499
GO:0003128
IEA
PLAZA Integrative Orthologyheart field specification FBgn0000499
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction FBgn0000499
GO:0003136
IEA
PLAZA Integrative Orthologynegative regulation of heart induction by canonical Wnt signaling pathway FBgn0000499
GO:0002165
IEA
PLAZA Integrative Orthologyinstar larval or pupal development FBgn0000499
GO:0007298
IEA
PLAZA Integrative Orthologyborder follicle cell migration FBgn0000499
GO:0051294
IEA
PLAZA Integrative Orthologyestablishment of spindle orientation FBgn0000499
GO:0042330
IEA
PLAZA Integrative Orthologytaxis FBgn0000499
GO:0051172
IEA
PLAZA Integrative Orthologynegative regulation of nitrogen compound metabolic process ENSG00000107404
GO:0051293
IEA
PLAZA Integrative Orthologyestablishment of spindle localization WBGene00001101
GO:0060560
IEA
PLAZA Integrative Orthologydevelopmental growth involved in morphogenesis FBgn0000499
GO:0007297
IEA
PLAZA Integrative Orthologyovarian follicle cell migration FBgn0000499
GO:1903047
IEA
PLAZA Integrative Orthologymitotic cell cycle process WBGene00001101
GO:2000043
IEA
PLAZA Integrative Orthologyregulation of cardiac cell fate specification FBgn0000499
GO:0035089
IEA
PLAZA Integrative Orthologyestablishment of apical/basal cell polarity FBgn0000499
GO:0007292
IEA
PLAZA Integrative Orthologyfemale gamete generation FBgn0000499
GO:0031324
IEA
PLAZA Integrative Orthologynegative regulation of cellular metabolic process ENSG00000107404
GO:0035088
IEA
PLAZA Integrative Orthologyestablishment or maintenance of apical/basal cell polarity FBgn0000499
GO:0032535
IEA
PLAZA Integrative Orthologyregulation of cellular component size FBgn0000499
GO:0001933
IEA
PLAZA Integrative Orthologynegative regulation of protein phosphorylation ENSG00000107404
GO:0098727
IEA
PLAZA Integrative Orthologymaintenance of cell number FBgn0000499
GO:0046530
IEA
PLAZA Integrative Orthologyphotoreceptor cell differentiation FBgn0000499
GO:0010769
IEA
PLAZA Integrative Orthologyregulation of cell morphogenesis involved in differentiation FBgn0000499
GO:0051674
IEA
PLAZA Integrative Orthologylocalization of cell FBgn0000499
GO:2000826
IEA
PLAZA Integrative Orthologyregulation of heart morphogenesis FBgn0000499
GO:0031329
IEA
PLAZA Integrative Orthologyregulation of cellular catabolic process ENSG00000107404
GO:0007367
IEA
PLAZA Integrative Orthologysegment polarity determination FBgn0000499
GO:0007365
IEA
PLAZA Integrative Orthologyperiodic partitioning FBgn0000499
GO:0022612
IEA
PLAZA Integrative Orthologygland morphogenesis FBgn0000499
GO:0010092
IEA
PLAZA Integrative Orthologyspecification of animal organ identity FBgn0000499
GO:0048707
IEA
PLAZA Integrative Orthologyinstar larval or pupal morphogenesis FBgn0000499
GO:0010770
IEA
PLAZA Integrative Orthologypositive regulation of cell morphogenesis involved in differentiation FBgn0000499
GO:0010631
IEA
PLAZA Integrative Orthologyepithelial cell migration FBgn0000499
GO:0007480
IEA
PLAZA Integrative Orthologyimaginal disc-derived leg morphogenesis FBgn0000499
GO:0031331
IEA
PLAZA Integrative Orthologypositive regulation of cellular catabolic process ENSG00000107404
GO:0100012
IEA
PLAZA Integrative Orthologyregulation of heart induction by canonical Wnt signaling pathway FBgn0000499
GO:0035019
IEA
PLAZA Integrative Orthologysomatic stem cell population maintenance FBgn0000499
GO:0003306
IEA
PLAZA Integrative OrthologyWnt signaling pathway involved in heart development FBgn0000499
GO:0006935
IEA
PLAZA Integrative Orthologychemotaxis FBgn0000499
GO:0110053
IEA
PLAZA Integrative Orthologyregulation of actin filament organization FBgn0000499
GO:0007478
IEA
PLAZA Integrative Orthologyleg disc morphogenesis FBgn0000499
GO:0000278
IEA
PLAZA Integrative Orthologymitotic cell cycle WBGene00001101
GO:1901800
IEA
PLAZA Integrative Orthologypositive regulation of proteasomal protein catabolic process ENSG00000107404
GO:0009894
IEA
PLAZA Integrative Orthologyregulation of catabolic process ENSG00000107404
GO:0009896
IEA
PLAZA Integrative Orthologypositive regulation of catabolic process ENSG00000107404
GO:0007476
IEA
PLAZA Integrative Orthologyimaginal disc-derived wing morphogenesis FBgn0000499
GO:0007350
IEA
PLAZA Integrative Orthologyblastoderm segmentation FBgn0000499
GO:0009892
IEA
PLAZA Integrative Orthologynegative regulation of metabolic process ENSG00000107404
GO:0007472
IEA
PLAZA Integrative Orthologywing disc morphogenesis FBgn0000499
GO:0070507
IEA
PLAZA Integrative Orthologyregulation of microtubule cytoskeleton organization WBGene00001101
GO:0051656
IEA
PLAZA Integrative Orthologyestablishment of organelle localization WBGene00001101
GO:0032434
IEA
PLAZA Integrative Orthologyregulation of proteasomal ubiquitin-dependent protein catabolic process ENSG00000107404
GO:0032436
IEA
PLAZA Integrative Orthologypositive regulation of proteasomal ubiquitin-dependent protein catabolic process ENSG00000107404
GO:0030010
IEA
PLAZA Integrative Orthologyestablishment of cell polarity FBgn0000499
GO:0051890
IEA
PLAZA Integrative Orthologyregulation of cardioblast differentiation FBgn0000499
GO:0051098
IEA
PLAZA Integrative Orthologyregulation of binding ENSG00000107404
GO:0150063
IEA
PLAZA Integrative Orthologyvisual system development FBgn0000499
GO:0051892
IEA
PLAZA Integrative Orthologynegative regulation of cardioblast differentiation FBgn0000499
GO:0060914
IEA
PLAZA Integrative Orthologyheart formation FBgn0000499
GO:0051653
IEA
PLAZA Integrative Orthologyspindle localization WBGene00001101
GO:0045773
IEA
PLAZA Integrative Orthologypositive regulation of axon extension FBgn0000499
GO:0060912
IEA
PLAZA Integrative Orthologycardiac cell fate specification FBgn0000499
GO:0060911
IEA
PLAZA Integrative Orthologycardiac cell fate commitment FBgn0000499
GO:0008593
IEA
PLAZA Integrative Orthologyregulation of Notch signaling pathway FBgn0000499
GO:0035152
IEA
PLAZA Integrative Orthologyregulation of tube architecture, open tracheal system FBgn0000499
GO:0035272
IEA
PLAZA Integrative Orthologyexocrine system development FBgn0000499
GO:0035151
IEA
PLAZA Integrative Orthologyregulation of tube size, open tracheal system FBgn0000499
GO:0035150
IEA
PLAZA Integrative Orthologyregulation of tube size FBgn0000499
GO:0061564
IEA
PLAZA Integrative Orthologyaxon development FBgn0000499
GO:0065008
IEA
PLAZA Integrative Orthologyregulation of biological quality ENSG00000107404
GO:0035159
IEA
PLAZA Integrative Orthologyregulation of tube length, open tracheal system FBgn0000499
GO:0034504
IEA
PLAZA Integrative Orthologyprotein localization to nucleus ENSG00000107404
GO:0001708
IEA
PLAZA Integrative Orthologycell fate specification FBgn0000499
GO:1905383
IEA
PLAZA Integrative Orthologyprotein localization to presynapse ENSG00000107404
GO:0051649
IEA
PLAZA Integrative Orthologyestablishment of localization in cell WBGene00001101
GO:0043473
IEA
PLAZA Integrative Orthologypigmentation FBgn0000499
GO:0030707
IEA
PLAZA Integrative Orthologyovarian follicle cell development FBgn0000499
GO:0001700
IEA
PLAZA Integrative Orthologyembryonic development via the syncytial blastoderm FBgn0000499
GO:0051640
IEA
PLAZA Integrative Orthologyorganelle localization WBGene00001101
GO:0030029
IEA
PLAZA Integrative Orthologyactin filament-based process FBgn0000499
GO:0007017
IEA
PLAZA Integrative Orthologymicrotubule-based process WBGene00001101
GO:0061458
IEA
PLAZA Integrative Orthologyreproductive system development FBgn0000499
GO:0008585
IEA
PLAZA Integrative Orthologyfemale gonad development FBgn0000499
GO:0051093
IEA
PLAZA Integrative Orthologynegative regulation of developmental process FBgn0000499
GO:0007015
IEA
PLAZA Integrative Orthologyactin filament organization FBgn0000499
GO:0008587
IEA
PLAZA Integrative Orthologyimaginal disc-derived wing margin morphogenesis FBgn0000499
GO:0061339
IEA
PLAZA Integrative Orthologyestablishment or maintenance of monopolar cell polarity FBgn0000499
GO:0022402
IEA
PLAZA Integrative Orthologycell cycle process WBGene00001101
GO:0061572
IEA
PLAZA Integrative Orthologyactin filament bundle organization FBgn0000499
GO:0009791
IEA
PLAZA Integrative Orthologypost-embryonic development FBgn0000499
GO:0036011
IEA
PLAZA Integrative Orthologyimaginal disc-derived leg segmentation FBgn0000499
GO:0035285
IEA
PLAZA Integrative Orthologyappendage segmentation FBgn0000499
GO:0030031
IEA
PLAZA Integrative Orthologycell projection assembly FBgn0000499
GO:0007010
IEA
PLAZA Integrative Orthologycytoskeleton organization WBGene00001101
GO:1905384
IEA
PLAZA Integrative Orthologyregulation of protein localization to presynapse ENSG00000107404
GO:1905386
IEA
PLAZA Integrative Orthologypositive regulation of protein localization to presynapse ENSG00000107404
GO:0150012
ISS
Gene Ontologypositive regulation of neuron projection arborization

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0048365
IEA
Genome ProjectRac GTPase binding
GO:0043621
IEA
Genome Projectprotein self-association
GO:0042802
IPI
Genome Projectidentical protein binding
GO:0042802
IPI
Gene Ontologyidentical protein binding9 10
GO:0030674
IEA
Genome Projectprotein binding, bridging
GO:0019904
IEA
Genome Projectprotein domain specific binding
GO:0019901
IEA
Genome Projectprotein kinase binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding7 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28
GO:0005109
IPI
Genome Projectfrizzled binding
GO:0005109
IPI
TAS
Gene Ontologyfrizzled binding4 29
GO:0070300
IEA
PLAZA Integrative Orthologyphosphatidic acid binding FBgn0000499
GO:0043168
IEA
PLAZA Integrative Orthologyanion binding FBgn0000499
GO:0043167
IEA
PLAZA Integrative Orthologyion binding FBgn0000499
GO:0032947
IEA
PLAZA Integrative Orthologyprotein-containing complex scaffold activity FBgn0000499
GO:0008289
IEA
PLAZA Integrative Orthologylipid binding FBgn0000499
GO:0005112
IEA
PLAZA Integrative OrthologyNotch binding FBgn0000499
GO:0030159
IEA
PLAZA Integrative Orthologyreceptor signaling complex scaffold activity FBgn0000499
GO:0005543
IEA
PLAZA Integrative Orthologyphospholipid binding FBgn0000499
GO:0008013
IEA
PLAZA Integrative Orthologybeta-catenin binding ENSG00000161202
GO:0002020
IEA
PLAZA Integrative Orthologyprotease binding ENSG00000161202
GO:0030971
IEA
PLAZA Integrative Orthologyreceptor tyrosine kinase binding WBGene00001101
GO:1990782
IEA
PLAZA Integrative Orthologyprotein tyrosine kinase binding WBGene00001101
GO:0046983
IEA
PLAZA Integrative Orthologyprotein dimerization activity ENSG00000161202
GO:0046982
IEA
PLAZA Integrative Orthologyprotein heterodimerization activity ENSG00000161202
GO:0005198
IEA
PLAZA Integrative Orthologystructural molecule activity FBgn0000499

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0045334
TAS
Genome Projectclathrin-coated endocytic vesicle
GO:0045334
TAS
Gene Ontologyclathrin-coated endocytic vesicle
GO:0045177
IEA
Genome Projectapical part of cell
GO:0031410
IDA
Genome Projectcytoplasmic vesicle
GO:0031410
IDA
Gene Ontologycytoplasmic vesicle30
GO:0016604
IDA
Genome Projectnuclear body
GO:0016604
IDA
Gene Ontologynuclear body
GO:0016328
IEA
Genome Projectlateral plasma membrane
GO:0016235
IDA
Genome Projectaggresome
GO:0016235
IDA
Gene Ontologyaggresome
GO:0005829
IBA
TAS
Genome Projectcytosol
GO:0005829
TAS
Gene Ontologycytosol
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005737
IDA
Gene Ontologycytoplasm30 31
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005654
IDA
Gene Ontologynucleoplasm
GO:0005634
ISS
Genome Projectnucleus
GO:0005634
ISS
Gene Ontologynucleus
GO:0033267
IEA
PLAZA Integrative Orthologyaxon part ENSG00000107404
GO:0099738
IEA
PLAZA Integrative Orthologycell cortex region FBgn0000499
GO:0005938
IEA
PLAZA Integrative Orthologycell cortex FBgn0000499
GO:0042995
IEA
PLAZA Integrative Orthologycell projection ENSG00000107404
GO:0097458
IEA
PLAZA Integrative Orthologyneuron part ENSG00000107404
GO:0120025
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection ENSG00000107404
GO:0120038
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection part ENSG00000107404
GO:0005694
IEA
PLAZA Integrative Orthologychromosome ENSG00000161202
GO:0005912
IEA
PLAZA Integrative Orthologyadherens junction FBgn0000499
GO:0000228
IEA
PLAZA Integrative Orthologynuclear chromosome ENSG00000161202
GO:0030427
IEA
PLAZA Integrative Orthologysite of polarized growth ENSG00000107404
GO:0030426
IEA
PLAZA Integrative Orthologygrowth cone ENSG00000107404
GO:0044427
IEA
PLAZA Integrative Orthologychromosomal part ENSG00000161202
GO:0099568
IEA
PLAZA Integrative Orthologycytoplasmic region FBgn0000499
GO:0030054
IEA
PLAZA Integrative Orthologycell junction FBgn0000499
GO:0000790
IEA
PLAZA Integrative Orthologynuclear chromatin ENSG00000161202
GO:0000785
IEA
PLAZA Integrative Orthologychromatin ENSG00000161202
GO:0045179
IEA
PLAZA Integrative Orthologyapical cortex FBgn0000499
GO:0150034
IEA
PLAZA Integrative Orthologydistal axon ENSG00000107404
GO:0044463
IEA
PLAZA Integrative Orthologycell projection part ENSG00000107404
GO:0043005
IEA
PLAZA Integrative Orthologyneuron projection ENSG00000107404
GO:0044454
IEA
PLAZA Integrative Orthologynuclear chromosome part ENSG00000161202
GO:0044448
IEA
PLAZA Integrative Orthologycell cortex part FBgn0000499
GO:0043232
IEA
PLAZA Integrative Orthologyintracellular non-membrane-bounded organelle ENSG00000161202
GO:0070161
IEA
PLAZA Integrative Orthologyanchoring junction FBgn0000499
GO:0043228
IEA
PLAZA Integrative Orthologynon-membrane-bounded organelle ENSG00000161202

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000591DEP domain
IPR001158DIX domain
IPR001478PDZ domain
IPR003351Dishevelled protein domain
IPR008339Dishevelled family
IPR008341Dishevelled-2
IPR011991ArsR-like helix-turn-helix domain
IPR015506Dishevelled-related protein
IPR024580Dishevelled C-terminal
IPR029071Ubiquitin-like domain superfamily

No MapMan annotations defined for this gene.
KeggID Description
K02353DVL; segment polarity protein dishevelled
No chloroplast target sequence found.