Gene: AT5G44280 (Arabidopsis thaliana)

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Gene Identifier
AT5G44280
Transcript Identifier
AT5G44280.2
Gene Type
Coding gene
Location
5 : 17836115-17839114 : negative

Family Information

Homologous gene family
HOM02SEM022037
(4 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

Curated Summary
Encodes a nuclear localized protein with similarity to animal polycomb repressive core complex1 (PRC1) core component RING.Appears to function redundantly with ATRING1b, a close paralog. Both interact physically with CLF and LHP1 and appear to function together to repress class I KNOX gene expression.
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Identifiers

Type Value
uniprotQ9FKW0
aliasARABIDOPSIS THALIANA RING 1A
aliasRING 1A
aliasRING1A
aliasATRING1A

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0045892
IGI
Gene Ontologynegative regulation of transcription, DNA-templated1 2
GO:0045814
IGI
Gene Ontologynegative regulation of gene expression, epigenetic1 2
GO:0010492
IMP
Gene Ontologymaintenance of shoot apical meristem identity1 2
GO:0010077
IMP
Gene Ontologymaintenance of inflorescence meristem identity1 2
GO:0010076
IMP
Gene Ontologymaintenance of floral meristem identity1 2
GO:0001709
IMP
Gene Ontologycell fate determination1 2
GO:0010564
IEA
PLAZA Integrative Orthologyregulation of cell cycle process ENSG00000121481
GO:0051276
IEA
PLAZA Integrative Orthologychromosome organization ENSG00000121481
GO:0007049
IEA
PLAZA Integrative Orthologycell cycle ENSG00000121481
GO:0006513
IEA
PLAZA Integrative Orthologyprotein monoubiquitination ENSG00000121481
GO:0043412
IEA
PLAZA Integrative Orthologymacromolecule modification ENSG00000121481
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization ENSG00000121481
GO:0044267
IEA
PLAZA Integrative Orthologycellular protein metabolic process ENSG00000121481
GO:1901564
IEA
PLAZA Integrative Orthologyorganonitrogen compound metabolic process ENSG00000121481
GO:0006464
IEA
PLAZA Integrative Orthologycellular protein modification process ENSG00000121481
GO:0045786
IEA
PLAZA Integrative Orthologynegative regulation of cell cycle ENSG00000121481
GO:0019538
IEA
PLAZA Integrative Orthologyprotein metabolic process ENSG00000121481
GO:0016567
IEA
PLAZA Integrative Orthologyprotein ubiquitination ENSG00000121481
GO:0070316
IEA
PLAZA Integrative Orthologyregulation of G0 to G1 transition ENSG00000121481
GO:0044092
IEA
PLAZA Integrative Orthologynegative regulation of molecular function ENSG00000121481
GO:0070317
IEA
PLAZA Integrative Orthologynegative regulation of G0 to G1 transition ENSG00000121481
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis ENSG00000121481
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization ENSG00000121481
GO:0033522
IEA
PLAZA Integrative Orthologyhistone H2A ubiquitination ENSG00000121481
GO:0045023
IEA
PLAZA Integrative OrthologyG0 to G1 transition ENSG00000121481
GO:0010948
IEA
PLAZA Integrative Orthologynegative regulation of cell cycle process ENSG00000121481
GO:0065009
IEA
PLAZA Integrative Orthologyregulation of molecular function ENSG00000121481
GO:0043433
IEA
PLAZA Integrative Orthologynegative regulation of DNA-binding transcription factor activity ENSG00000121481
GO:0010390
IEA
PLAZA Integrative Orthologyhistone monoubiquitination ENSG00000121481
GO:0032446
IEA
PLAZA Integrative Orthologyprotein modification by small protein conjugation ENSG00000121481
GO:0070647
IEA
PLAZA Integrative Orthologyprotein modification by small protein conjugation or removal ENSG00000121481
GO:0051726
IEA
PLAZA Integrative Orthologyregulation of cell cycle ENSG00000121481
GO:0016574
IEA
PLAZA Integrative Orthologyhistone ubiquitination ENSG00000121481
GO:0016570
IEA
PLAZA Integrative Orthologyhistone modification ENSG00000121481
GO:0035518
IEA
PLAZA Integrative Orthologyhistone H2A monoubiquitination ENSG00000121481
GO:0051090
IEA
PLAZA Integrative Orthologyregulation of DNA-binding transcription factor activity ENSG00000121481
GO:0006325
IEA
PLAZA Integrative Orthologychromatin organization ENSG00000121481
GO:0022402
IEA
PLAZA Integrative Orthologycell cycle process ENSG00000121481
GO:0036211
IEA
PLAZA Integrative Orthologyprotein modification process ENSG00000121481
GO:0016569
IEA
PLAZA Integrative Orthologycovalent chromatin modification ENSG00000121481

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Gene Ontologyprotein binding1 2
GO:0008270
ISS
Gene Ontologyzinc ion binding3
GO:0016740
IEA
PLAZA Integrative Orthologytransferase activity ENSG00000121481
GO:0004842
IEA
PLAZA Integrative Orthologyubiquitin-protein transferase activity ENSG00000121481
GO:0003682
IEA
PLAZA Integrative Orthologychromatin binding ENSG00000121481
GO:0140096
IEA
PLAZA Integrative Orthologycatalytic activity, acting on a protein ENSG00000121481
GO:0019787
IEA
PLAZA Integrative Orthologyubiquitin-like protein transferase activity ENSG00000121481
GO:0003824
IEA
PLAZA Integrative Orthologycatalytic activity ENSG00000121481
GO:0019904
IEA
PLAZA Integrative Orthologyprotein domain specific binding ENSG00000121481
GO:0071535
IEA
PLAZA Integrative OrthologyRING-like zinc finger domain binding ENSG00000121481

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0035102
IPI
Gene OntologyPRC1 complex1 2
GO:0005634
IDA
ISM
Gene Ontologynucleus1 2 4
GO:0005737
ISM
Gene Ontologycytoplasm4
GO:0070013
IEA
PLAZA Integrative Orthologyintracellular organelle lumen ENSG00000121481
GO:0044665
IEA
PLAZA Integrative OrthologyMLL1/2 complex ENSG00000121481
GO:0035097
IEA
PLAZA Integrative Orthologyhistone methyltransferase complex ENSG00000121481
GO:0031974
IEA
PLAZA Integrative Orthologymembrane-enclosed lumen ENSG00000121481
GO:0005654
IEA
PLAZA Integrative Orthologynucleoplasm ENSG00000121481
GO:0031981
IEA
PLAZA Integrative Orthologynuclear lumen ENSG00000121481
GO:0044451
IEA
PLAZA Integrative Orthologynucleoplasm part ENSG00000121481
GO:0043233
IEA
PLAZA Integrative Orthologyorganelle lumen ENSG00000121481
GO:0071339
IEA
PLAZA Integrative OrthologyMLL1 complex ENSG00000121481
GO:0034708
IEA
PLAZA Integrative Orthologymethyltransferase complex ENSG00000121481
GO:0016604
IEA
PLAZA Integrative Orthologynuclear body ENSG00000121481

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001841Zinc finger, RING-type
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR017907Zinc finger, RING-type, conserved site

No MapMan annotations defined for this gene.
KeggID Description
K10695RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
No chloroplast target sequence found.