Gene: AT5G22110 (Arabidopsis thaliana)

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Gene Identifier
AT5G22110
Transcript Identifier
AT5G22110.1
Gene Type
Coding gene
Location
5 : 7331071-7334178 : negative

Family Information

Homologous gene family
HOM02SEM003076
(25 genes in 22 species)
specific family

Descriptions

Description
DNA polymerase epsilon subunit B2
Curated Summary
Encodes a protein with similarity to DNA polymerase epsilon subunit B an essential gene that is required for DNA replication. Homozygous mutants are embryo lethal. Expressed in meristematic , rapidly dividing regions.
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Identifiers

Type Value
aliasATDPB2
aliasCYL2
aliasCYCLOPS 2
aliasDPB2

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006260
IEA
InterProDNA replication
GO:0006261
IEA
InterProDNA-dependent DNA replication
GO:0051781
IMP
Gene Ontologypositive regulation of cell division1 2
GO:0009793
IMP
Gene Ontologyembryo development ending in seed dormancy1 2
GO:0010564
IEA
PLAZA Integrative Orthologyregulation of cell cycle process FBgn0035644
GO:2000105
IEA
PLAZA Integrative Orthologypositive regulation of DNA-dependent DNA replication FBgn0035644
GO:0010605
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule metabolic process YPR175W
GO:0010604
IEA
PLAZA Integrative Orthologypositive regulation of macromolecule metabolic process FBgn0035644
GO:0044271
IEA
PLAZA Integrative Orthologycellular nitrogen compound biosynthetic process YPR175W
GO:0007049
IEA
PLAZA Integrative Orthologycell cycle SPBP8B7.14c
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization YPR175W
GO:0044786
IEA
PLAZA Integrative Orthologycell cycle DNA replication SPBP8B7.14c
GO:0006355
IEA
PLAZA Integrative Orthologyregulation of transcription, DNA-templated YPR175W
GO:0006351
IEA
PLAZA Integrative Orthologytranscription, DNA-templated YPR175W
GO:0050896
IEA
PLAZA Integrative Orthologyresponse to stimulus YPR175W
GO:0010557
IEA
PLAZA Integrative Orthologypositive regulation of macromolecule biosynthetic process FBgn0035644
GO:0097549
IEA
PLAZA Integrative Orthologychromatin organization involved in negative regulation of transcription YPR175W
GO:0010558
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule biosynthetic process YPR175W
GO:0034401
IEA
PLAZA Integrative Orthologychromatin organization involved in regulation of transcription YPR175W
GO:0033554
IEA
PLAZA Integrative Orthologycellular response to stress YPR175W
GO:0010556
IEA
PLAZA Integrative Orthologyregulation of macromolecule biosynthetic process YPR175W
GO:0000082
IEA
PLAZA Integrative OrthologyG1/S transition of mitotic cell cycle ENSG00000100479
GO:1903507
IEA
PLAZA Integrative Orthologynegative regulation of nucleic acid-templated transcription YPR175W
GO:1903506
IEA
PLAZA Integrative Orthologyregulation of nucleic acid-templated transcription YPR175W
GO:0006342
IEA
PLAZA Integrative Orthologychromatin silencing YPR175W
GO:0045740
IEA
PLAZA Integrative Orthologypositive regulation of DNA replication FBgn0035644
GO:0044772
IEA
PLAZA Integrative Orthologymitotic cell cycle phase transition ENSG00000100479
GO:0070828
IEA
PLAZA Integrative Orthologyheterochromatin organization YPR175W
GO:0032875
IEA
PLAZA Integrative Orthologyregulation of DNA endoreduplication FBgn0035644
GO:0019438
IEA
PLAZA Integrative Orthologyaromatic compound biosynthetic process YPR175W
GO:0032877
IEA
PLAZA Integrative Orthologypositive regulation of DNA endoreduplication FBgn0035644
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis YPR175W
GO:0010467
IEA
PLAZA Integrative Orthologygene expression YPR175W
GO:0034654
IEA
PLAZA Integrative Orthologynucleobase-containing compound biosynthetic process YPR175W
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization YPR175W
GO:0010468
IEA
PLAZA Integrative Orthologyregulation of gene expression YPR175W
GO:0051054
IEA
PLAZA Integrative Orthologypositive regulation of DNA metabolic process FBgn0035644
GO:0044770
IEA
PLAZA Integrative Orthologycell cycle phase transition ENSG00000100479
GO:0042592
IEA
PLAZA Integrative Orthologyhomeostatic process ENSG00000100479
GO:0010629
IEA
PLAZA Integrative Orthologynegative regulation of gene expression YPR175W
GO:0009889
IEA
PLAZA Integrative Orthologyregulation of biosynthetic process YPR175W
GO:2001141
IEA
PLAZA Integrative Orthologyregulation of RNA biosynthetic process YPR175W
GO:0051726
IEA
PLAZA Integrative Orthologyregulation of cell cycle FBgn0035644
GO:0051171
IEA
PLAZA Integrative Orthologyregulation of nitrogen compound metabolic process YPR175W
GO:0051173
IEA
PLAZA Integrative Orthologypositive regulation of nitrogen compound metabolic process FBgn0035644
GO:0051052
IEA
PLAZA Integrative Orthologyregulation of DNA metabolic process FBgn0035644
GO:0051172
IEA
PLAZA Integrative Orthologynegative regulation of nitrogen compound metabolic process YPR175W
GO:1903047
IEA
PLAZA Integrative Orthologymitotic cell cycle process SPBP8B7.14c
GO:0090329
IEA
PLAZA Integrative Orthologyregulation of DNA-dependent DNA replication FBgn0035644
GO:0031324
IEA
PLAZA Integrative Orthologynegative regulation of cellular metabolic process YPR175W
GO:0031323
IEA
PLAZA Integrative Orthologyregulation of cellular metabolic process YPR175W
GO:0080090
IEA
PLAZA Integrative Orthologyregulation of primary metabolic process YPR175W
GO:0031326
IEA
PLAZA Integrative Orthologyregulation of cellular biosynthetic process YPR175W
GO:0031325
IEA
PLAZA Integrative Orthologypositive regulation of cellular metabolic process FBgn0035644
GO:0032774
IEA
PLAZA Integrative OrthologyRNA biosynthetic process YPR175W
GO:0051716
IEA
PLAZA Integrative Orthologycellular response to stimulus YPR175W
GO:0051276
IEA
PLAZA Integrative Orthologychromosome organization YPR175W
GO:0031328
IEA
PLAZA Integrative Orthologypositive regulation of cellular biosynthetic process FBgn0035644
GO:0031327
IEA
PLAZA Integrative Orthologynegative regulation of cellular biosynthetic process YPR175W
GO:0006312
IEA
PLAZA Integrative Orthologymitotic recombination ENSG00000100479
GO:0040029
IEA
PLAZA Integrative Orthologyregulation of gene expression, epigenetic YPR175W
GO:0006950
IEA
PLAZA Integrative Orthologyresponse to stress YPR175W
GO:0006275
IEA
PLAZA Integrative Orthologyregulation of DNA replication FBgn0035644
GO:0000722
IEA
PLAZA Integrative Orthologytelomere maintenance via recombination ENSG00000100479
GO:0000723
IEA
PLAZA Integrative Orthologytelomere maintenance ENSG00000100479
GO:0006310
IEA
PLAZA Integrative OrthologyDNA recombination ENSG00000100479
GO:0060255
IEA
PLAZA Integrative Orthologyregulation of macromolecule metabolic process YPR175W
GO:0006270
IEA
PLAZA Integrative OrthologyDNA replication initiation SPBP8B7.14c
GO:0016458
IEA
PLAZA Integrative Orthologygene silencing YPR175W
GO:0070868
IEA
PLAZA Integrative Orthologyheterochromatin organization involved in chromatin silencing YPR175W
GO:0019985
IEA
PLAZA Integrative Orthologytranslesion synthesis YPR175W
GO:1902292
IEA
PLAZA Integrative Orthologycell cycle DNA replication initiation SPBP8B7.14c
GO:0019222
IEA
PLAZA Integrative Orthologyregulation of metabolic process YPR175W
GO:0018130
IEA
PLAZA Integrative Orthologyheterocycle biosynthetic process YPR175W
GO:0016070
IEA
PLAZA Integrative OrthologyRNA metabolic process YPR175W
GO:1902969
IEA
PLAZA Integrative Orthologymitotic DNA replication SPBP8B7.14c
GO:0006301
IEA
PLAZA Integrative Orthologypostreplication repair YPR175W
GO:0000278
IEA
PLAZA Integrative Orthologymitotic cell cycle SPBP8B7.14c
GO:0045787
IEA
PLAZA Integrative Orthologypositive regulation of cell cycle FBgn0035644
GO:0042276
IEA
PLAZA Integrative Orthologyerror-prone translesion synthesis YPR175W
GO:1902975
IEA
PLAZA Integrative Orthologymitotic DNA replication initiation SPBP8B7.14c
GO:0009890
IEA
PLAZA Integrative Orthologynegative regulation of biosynthetic process YPR175W
GO:0009891
IEA
PLAZA Integrative Orthologypositive regulation of biosynthetic process FBgn0035644
GO:0009892
IEA
PLAZA Integrative Orthologynegative regulation of metabolic process YPR175W
GO:1901362
IEA
PLAZA Integrative Orthologyorganic cyclic compound biosynthetic process YPR175W
GO:0009893
IEA
PLAZA Integrative Orthologypositive regulation of metabolic process FBgn0035644
GO:0019219
IEA
PLAZA Integrative Orthologyregulation of nucleobase-containing compound metabolic process YPR175W
GO:0097659
IEA
PLAZA Integrative Orthologynucleic acid-templated transcription YPR175W
GO:0051252
IEA
PLAZA Integrative Orthologyregulation of RNA metabolic process YPR175W
GO:0051253
IEA
PLAZA Integrative Orthologynegative regulation of RNA metabolic process YPR175W
GO:0045934
IEA
PLAZA Integrative Orthologynegative regulation of nucleobase-containing compound metabolic process YPR175W
GO:0044843
IEA
PLAZA Integrative Orthologycell cycle G1/S phase transition ENSG00000100479
GO:0006974
IEA
PLAZA Integrative Orthologycellular response to DNA damage stimulus YPR175W
GO:0048523
IEA
PLAZA Integrative Orthologynegative regulation of cellular process YPR175W
GO:0042023
IEA
PLAZA Integrative OrthologyDNA endoreduplication FBgn0035644
GO:0090068
IEA
PLAZA Integrative Orthologypositive regulation of cell cycle process FBgn0035644
GO:0045935
IEA
PLAZA Integrative Orthologypositive regulation of nucleobase-containing compound metabolic process FBgn0035644
GO:0045814
IEA
PLAZA Integrative Orthologynegative regulation of gene expression, epigenetic YPR175W
GO:0065008
IEA
PLAZA Integrative Orthologyregulation of biological quality ENSG00000100479
GO:0032200
IEA
PLAZA Integrative Orthologytelomere organization ENSG00000100479
GO:2000112
IEA
PLAZA Integrative Orthologyregulation of cellular macromolecule biosynthetic process YPR175W
GO:2000113
IEA
PLAZA Integrative Orthologynegative regulation of cellular macromolecule biosynthetic process YPR175W
GO:0071897
IEA
PLAZA Integrative OrthologyDNA biosynthetic process YPR175W
GO:0045892
IEA
PLAZA Integrative Orthologynegative regulation of transcription, DNA-templated YPR175W
GO:0060249
IEA
PLAZA Integrative Orthologyanatomical structure homeostasis ENSG00000100479
GO:1902679
IEA
PLAZA Integrative Orthologynegative regulation of RNA biosynthetic process YPR175W
GO:0048519
IEA
PLAZA Integrative Orthologynegative regulation of biological process YPR175W
GO:0006325
IEA
PLAZA Integrative Orthologychromatin organization YPR175W
GO:0000731
IEA
PLAZA Integrative OrthologyDNA synthesis involved in DNA repair YPR175W
GO:1902315
IEA
PLAZA Integrative Orthologynuclear cell cycle DNA replication initiation SPBP8B7.14c
GO:0045005
IEA
PLAZA Integrative OrthologyDNA-dependent DNA replication maintenance of fidelity YPR175W
GO:0022402
IEA
PLAZA Integrative Orthologycell cycle process SPBP8B7.14c
GO:0006281
IEA
PLAZA Integrative OrthologyDNA repair YPR175W
GO:0033260
IEA
PLAZA Integrative Orthologynuclear DNA replication SPBP8B7.14c

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
IEA
InterProDNA binding
GO:0003887
ISS
Gene OntologyDNA-directed DNA polymerase activity3
GO:0003887
IEA
InterProDNA-directed DNA polymerase activity
GO:0070182
IPI
Gene OntologyDNA polymerase binding1 2
GO:0030337
IEA
PLAZA Integrative OrthologyDNA polymerase processivity factor activity YPR175W
GO:0098772
IEA
PLAZA Integrative Orthologymolecular function regulator YPR175W
GO:0030234
IEA
PLAZA Integrative Orthologyenzyme regulator activity YPR175W
GO:0003697
IEA
PLAZA Integrative Orthologysingle-stranded DNA binding YPR175W
GO:0003690
IEA
PLAZA Integrative Orthologydouble-stranded DNA binding YPR175W

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISS, ISM
Gene Ontologynucleus3 4
GO:0005634
IEA
InterPronucleus
GO:0008622
IPI
Gene Ontologyepsilon DNA polymerase complex1 2
GO:0005654
IEA
PLAZA Integrative Orthologynucleoplasm SPBP8B7.14c
GO:0031261
IEA
PLAZA Integrative OrthologyDNA replication preinitiation complex SPBP8B7.14c
GO:0032993
IEA
PLAZA Integrative Orthologyprotein-DNA complex SPBP8B7.14c
GO:0000790
IEA
PLAZA Integrative Orthologynuclear chromatin SPBP8B7.14c
GO:0000785
IEA
PLAZA Integrative Orthologychromatin SPBP8B7.14c
GO:0005829
IEA
PLAZA Integrative Orthologycytosol SPBP8B7.14c
GO:0016604
IEA
PLAZA Integrative Orthologynuclear body ENSG00000100479
GO:0005737
IEA
PLAZA Integrative Orthologycytoplasm SPBP8B7.14c
GO:0044451
IEA
PLAZA Integrative Orthologynucleoplasm part SPBP8B7.14c
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part SPBP8B7.14c

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR007185DNA polymerase alpha/epsilon, subunit B
IPR016266DNA polymerase epsilon, subunit B

No MapMan annotations defined for this gene.
KeggID Description
K02325POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
No chloroplast target sequence found.