Gene: AT5G18650 (Arabidopsis thaliana)

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Gene Identifier
AT5G18650
Transcript Identifier
AT5G18650.1
Gene Type
Coding gene
Location
5 : 6218260-6220374 : positive

Family Information

Homologous gene family
HOM02SEM000952
(50 genes in 18 species)
specific family

Descriptions

Description
CHY-type/CTCHY-type/RING-type Zinc finger protein
Curated Summary
Encodes a RING-type E3 ubiquitin ligase that interacts with and ubiquitinates MYB30, leads to MYB30 proteasomal degradation and downregulation of its transcriptional activity. Since MYB30 is a positive regulator of Arabidopsis HR and defence responses, MIEL1 is involved in the negative regulation of these processes.
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Identifiers

Type Value
aliasMIEL1
aliasMYB30-Interacting E3 Ligase 1

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016567
IDA
Gene Ontologyprotein ubiquitination1 2
GO:0016567
IEA
InterProprotein ubiquitination
GO:1901485
IDA
Gene Ontologypositive regulation of transcription factor catabolic process1 2
GO:1900425
IMP
Gene Ontologynegative regulation of defense response to bacterium1 2
GO:0031401
IEA
PLAZA Integrative Orthologypositive regulation of protein modification process ENSG00000163743
GO:0051716
IEA
PLAZA Integrative Orthologycellular response to stimulus ENSG00000163743
GO:0044271
IEA
PLAZA Integrative Orthologycellular nitrogen compound biosynthetic process ENSG00000163743
GO:1901576
IEA
PLAZA Integrative Orthologyorganic substance biosynthetic process ENSG00000163743
GO:0034645
IEA
PLAZA Integrative Orthologycellular macromolecule biosynthetic process ENSG00000163743
GO:0070987
IEA
PLAZA Integrative Orthologyerror-free translesion synthesis ENSG00000163743
GO:0019985
IEA
PLAZA Integrative Orthologytranslesion synthesis ENSG00000163743
GO:0034641
IEA
PLAZA Integrative Orthologycellular nitrogen compound metabolic process ENSG00000163743
GO:0033554
IEA
PLAZA Integrative Orthologycellular response to stress ENSG00000163743
GO:0018130
IEA
PLAZA Integrative Orthologyheterocycle biosynthetic process ENSG00000163743
GO:0046483
IEA
PLAZA Integrative Orthologyheterocycle metabolic process ENSG00000163743
GO:0006301
IEA
PLAZA Integrative Orthologypostreplication repair ENSG00000163743
GO:0009058
IEA
PLAZA Integrative Orthologybiosynthetic process ENSG00000163743
GO:0009059
IEA
PLAZA Integrative Orthologymacromolecule biosynthetic process ENSG00000163743
GO:1901362
IEA
PLAZA Integrative Orthologyorganic cyclic compound biosynthetic process ENSG00000163743
GO:1901360
IEA
PLAZA Integrative Orthologyorganic cyclic compound metabolic process ENSG00000163743
GO:0019438
IEA
PLAZA Integrative Orthologyaromatic compound biosynthetic process ENSG00000163743
GO:0034654
IEA
PLAZA Integrative Orthologynucleobase-containing compound biosynthetic process ENSG00000163743
GO:0006725
IEA
PLAZA Integrative Orthologycellular aromatic compound metabolic process ENSG00000163743
GO:0006139
IEA
PLAZA Integrative Orthologynucleobase-containing compound metabolic process ENSG00000163743
GO:0044249
IEA
PLAZA Integrative Orthologycellular biosynthetic process ENSG00000163743
GO:0006259
IEA
PLAZA Integrative OrthologyDNA metabolic process ENSG00000163743
GO:0006974
IEA
PLAZA Integrative Orthologycellular response to DNA damage stimulus ENSG00000163743
GO:0090304
IEA
PLAZA Integrative Orthologynucleic acid metabolic process ENSG00000163743
GO:0031396
IEA
PLAZA Integrative Orthologyregulation of protein ubiquitination ENSG00000163743
GO:0031399
IEA
PLAZA Integrative Orthologyregulation of protein modification process ENSG00000163743
GO:0031398
IEA
PLAZA Integrative Orthologypositive regulation of protein ubiquitination ENSG00000163743
GO:0071897
IEA
PLAZA Integrative OrthologyDNA biosynthetic process ENSG00000163743
GO:0000731
IEA
PLAZA Integrative OrthologyDNA synthesis involved in DNA repair ENSG00000163743
GO:1903320
IEA
PLAZA Integrative Orthologyregulation of protein modification by small protein conjugation or removal ENSG00000163743
GO:1903322
IEA
PLAZA Integrative Orthologypositive regulation of protein modification by small protein conjugation or removal ENSG00000163743
GO:0006281
IEA
PLAZA Integrative OrthologyDNA repair ENSG00000163743

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008270
ISS
Gene Ontologyzinc ion binding3
GO:0008270
IEA
InterProzinc ion binding
GO:0046872
IEA
InterPrometal ion binding
GO:0005515
IEA
InterProprotein binding
GO:0008134
IPI
Gene Ontologytranscription factor binding1 2
GO:0004842
IDA
Gene Ontologyubiquitin-protein transferase activity1 2
GO:0042803
IEA
PLAZA Integrative Orthologyprotein homodimerization activity ENSG00000163743
GO:0042802
IEA
PLAZA Integrative Orthologyidentical protein binding ENSG00000163743
GO:0046983
IEA
PLAZA Integrative Orthologyprotein dimerization activity ENSG00000163743
GO:0002039
IEA
PLAZA Integrative Orthologyp53 binding ENSG00000163743

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
Gene Ontologycytoplasm1 2
GO:0005634
IDA
ISM
Gene Ontologynucleus1 2 4
GO:0070013
IEA
PLAZA Integrative Orthologyintracellular organelle lumen ENSG00000163743
GO:1990234
IEA
PLAZA Integrative Orthologytransferase complex ENSG00000163743
GO:0044422
IEA
PLAZA Integrative Orthologyorganelle part ENSG00000163743
GO:0044428
IEA
PLAZA Integrative Orthologynuclear part ENSG00000163743
GO:0031974
IEA
PLAZA Integrative Orthologymembrane-enclosed lumen ENSG00000163743
GO:0005654
IEA
PLAZA Integrative Orthologynucleoplasm ENSG00000163743
GO:1902494
IEA
PLAZA Integrative Orthologycatalytic complex ENSG00000163743
GO:0032991
IEA
PLAZA Integrative Orthologyprotein-containing complex ENSG00000163743
GO:0031981
IEA
PLAZA Integrative Orthologynuclear lumen ENSG00000163743
GO:0000151
IEA
PLAZA Integrative Orthologyubiquitin ligase complex ENSG00000163743
GO:0044446
IEA
PLAZA Integrative Orthologyintracellular organelle part ENSG00000163743
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part ENSG00000163743
GO:0043233
IEA
PLAZA Integrative Orthologyorganelle lumen ENSG00000163743
GO:0005829
IEA
PLAZA Integrative Orthologycytosol ENSG00000163743

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR031109Ring finger and CHY zinc finger domain-containing protein, plant
IPR008913Zinc finger, CHY-type
IPR018957Zinc finger, C3HC4 RING-type
IPR017921Zinc finger, CTCHY-type
IPR001841Zinc finger, RING-type

No MapMan annotations defined for this gene.
KeggID Description
K10144RCHY1, PIRH2; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
No chloroplast target sequence found.