Gene: AT5G08335 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT5G08335
Transcript Identifier
AT5G08335.1
Gene Type
Coding gene
Location
5 : 2683012-2683605 : positive

Family Information

Homologous gene family
HOM02SEM002401
(29 genes in 21 species)
specific family
Orthologous gene family
ORTHO02SEM002773
(27 genes in 21 species)
specific family
Duplication type
Block duplicate

Descriptions

Description
Isoprenylcysteine carboxyl methyltransferase (ICMT) family
Curated Summary
Encodes an isoprenyl cysteine methylatransferase (ICMT) involved in the post-translational processing of proteins that have a C-terminal CaaX box. This protein appears to have higher catalytic activity and a higher transcript expression level than the other ICMT present in Arabidopsis (At5g23320). Analysis of ICMT RNAi lines suggests that this protein is involved in flower and stem development.
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Identifiers

Type Value
uniprotQ93W54
aliasARABIDOPSIS THALIANA ISOPRENYL CYSTEINE METHYLTRANSFERASE B
aliasICMTB
aliasATSTE14B
aliasATICMTB
aliasISOPRENYL CYSTEINE METHYLTRANSFERASE B

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006481
ISS
Gene OntologyC-terminal protein methylation1
GO:0006481
IEA
InterProC-terminal protein methylation
GO:0048367
IMP
Gene Ontologyshoot system development2 3
GO:0009908
IMP
Gene Ontologyflower development2 3
GO:0009788
NAS
Gene Ontologynegative regulation of abscisic acid-activated signaling pathway4 5
GO:0043900
IEA
PLAZA Integrative Orthologyregulation of multi-organism process SPAC10F6.12c
GO:0018229
IEA
PLAZA Integrative Orthologypeptidyl-L-cysteine methyl ester biosynthetic process from peptidyl-cysteine SPAC10F6.12c
GO:0043902
IEA
PLAZA Integrative Orthologypositive regulation of multi-organism process SPAC10F6.12c
GO:0070727
IEA
PLAZA Integrative Orthologycellular macromolecule localization SPAC10F6.12c
GO:2000241
IEA
PLAZA Integrative Orthologyregulation of reproductive process SPAC10F6.12c
GO:0015031
IEA
PLAZA Integrative Orthologyprotein transport ENSG00000116237
GO:0008104
IEA
PLAZA Integrative Orthologyprotein localization SPAC10F6.12c
GO:0006886
IEA
PLAZA Integrative Orthologyintracellular protein transport ENSG00000116237
GO:0048518
IEA
PLAZA Integrative Orthologypositive regulation of biological process SPAC10F6.12c
GO:0051641
IEA
PLAZA Integrative Orthologycellular localization SPAC10F6.12c
GO:0018193
IEA
PLAZA Integrative Orthologypeptidyl-amino acid modification SPAC10F6.12c
GO:0048522
IEA
PLAZA Integrative Orthologypositive regulation of cellular process SPAC10F6.12c
GO:0018350
IEA
PLAZA Integrative Orthologyprotein esterification SPAC10F6.12c
GO:0018198
IEA
PLAZA Integrative Orthologypeptidyl-cysteine modification SPAC10F6.12c
GO:0018351
IEA
PLAZA Integrative Orthologypeptidyl-cysteine esterification SPAC10F6.12c
GO:0051604
IEA
PLAZA Integrative Orthologyprotein maturation SPAC10F6.12c
GO:0051649
IEA
PLAZA Integrative Orthologyestablishment of localization in cell ENSG00000116237
GO:0000749
IEA
PLAZA Integrative Orthologyresponse to pheromone triggering conjugation with cellular fusion SPAC10F6.12c
GO:0046907
IEA
PLAZA Integrative Orthologyintracellular transport ENSG00000116237
GO:0000747
IEA
PLAZA Integrative Orthologyconjugation with cellular fusion SPAC10F6.12c
GO:0000746
IEA
PLAZA Integrative Orthologyconjugation SPAC10F6.12c
GO:0044764
IEA
PLAZA Integrative Orthologymulti-organism cellular process SPAC10F6.12c
GO:0006612
IEA
PLAZA Integrative Orthologyprotein targeting to membrane ENSG00000116237
GO:0006810
IEA
PLAZA Integrative Orthologytransport ENSG00000116237
GO:0045184
IEA
PLAZA Integrative Orthologyestablishment of protein localization ENSG00000116237
GO:0006605
IEA
PLAZA Integrative Orthologyprotein targeting ENSG00000116237
GO:0051179
IEA
PLAZA Integrative Orthologylocalization SPAC10F6.12c
GO:0072657
IEA
PLAZA Integrative Orthologyprotein localization to membrane ENSG00000116237
GO:0010467
IEA
PLAZA Integrative Orthologygene expression SPAC10F6.12c
GO:0019236
IEA
PLAZA Integrative Orthologyresponse to pheromone SPAC10F6.12c
GO:2000243
IEA
PLAZA Integrative Orthologypositive regulation of reproductive process SPAC10F6.12c
GO:0071444
IEA
PLAZA Integrative Orthologycellular response to pheromone SPAC10F6.12c
GO:0019953
IEA
PLAZA Integrative Orthologysexual reproduction SPAC10F6.12c
GO:0015833
IEA
PLAZA Integrative Orthologypeptide transport ENSG00000116237
GO:0034613
IEA
PLAZA Integrative Orthologycellular protein localization SPAC10F6.12c
GO:0090150
IEA
PLAZA Integrative Orthologyestablishment of protein localization to membrane ENSG00000116237
GO:0046999
IEA
PLAZA Integrative Orthologyregulation of conjugation SPAC10F6.12c
GO:0071432
IEA
PLAZA Integrative Orthologypeptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion SPAC10F6.12c
GO:0033036
IEA
PLAZA Integrative Orthologymacromolecule localization SPAC10F6.12c
GO:0051704
IEA
PLAZA Integrative Orthologymulti-organism process SPAC10F6.12c
GO:0140253
IEA
PLAZA Integrative Orthologycell-cell fusion SPAC10F6.12c
GO:0031139
IEA
PLAZA Integrative Orthologypositive regulation of conjugation with cellular fusion SPAC10F6.12c
GO:0031136
IEA
PLAZA Integrative Orthologypositive regulation of conjugation SPAC10F6.12c
GO:0031137
IEA
PLAZA Integrative Orthologyregulation of conjugation with cellular fusion SPAC10F6.12c
GO:0044703
IEA
PLAZA Integrative Orthologymulti-organism reproductive process SPAC10F6.12c
GO:0071705
IEA
PLAZA Integrative Orthologynitrogen compound transport ENSG00000116237
GO:0007323
IEA
PLAZA Integrative Orthologypeptide pheromone maturation SPAC10F6.12c
GO:0042886
IEA
PLAZA Integrative Orthologyamide transport ENSG00000116237
GO:0051234
IEA
PLAZA Integrative Orthologyestablishment of localization ENSG00000116237
GO:0018125
IEA
PLAZA Integrative Orthologypeptidyl-cysteine methylation SPAC10F6.12c
GO:0071702
IEA
PLAZA Integrative Orthologyorganic substance transport ENSG00000116237

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004671
IDA, IGI
ISS
Gene Ontologyprotein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity1 4 5
GO:0004671
IEA
InterProprotein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016021
IEA
InterProintegral component of membrane
GO:0005783
IDA
Gene Ontologyendoplasmic reticulum2 3
GO:0005783
IEA
InterProendoplasmic reticulum
GO:0044432
IEA
PLAZA Integrative Orthologyendoplasmic reticulum part YDR410C
GO:0005789
IEA
PLAZA Integrative Orthologyendoplasmic reticulum membrane YDR410C
GO:0044446
IEA
PLAZA Integrative Orthologyintracellular organelle part YDR410C
GO:0005635
IEA
PLAZA Integrative Orthologynuclear envelope YDR410C
GO:0005634
IEA
PLAZA Integrative Orthologynucleus YDR410C
GO:0005637
IEA
PLAZA Integrative Orthologynuclear inner membrane YDR410C
GO:0098827
IEA
PLAZA Integrative Orthologyendoplasmic reticulum subcompartment YDR410C
GO:0031984
IEA
PLAZA Integrative Orthologyorganelle subcompartment YDR410C
GO:0031975
IEA
PLAZA Integrative Orthologyenvelope YDR410C
GO:0019866
IEA
PLAZA Integrative Orthologyorganelle inner membrane YDR410C
GO:0044428
IEA
PLAZA Integrative Orthologynuclear part YDR410C
GO:0044422
IEA
PLAZA Integrative Orthologyorganelle part YDR410C
GO:0031090
IEA
PLAZA Integrative Orthologyorganelle membrane YDR410C
GO:0031967
IEA
PLAZA Integrative Orthologyorganelle envelope YDR410C
GO:0031965
IEA
PLAZA Integrative Orthologynuclear membrane YDR410C
GO:0042175
IEA
PLAZA Integrative Orthologynuclear outer membrane-endoplasmic reticulum membrane network YDR410C

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR007269Isoprenylcysteine carboxyl methyltransferase
IPR025770Protein-S-isoprenylcysteine O-methyltransferase

No MapMan annotations defined for this gene.
KeggID Description
K00587ICMT, STE14; protein-S-isoprenylcysteine O-methyltransferase [EC:2.1.1.100]
No chloroplast target sequence found.