Gene: AT4G18010 (Arabidopsis thaliana)

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Gene Identifier
AT4G18010
Transcript Identifier
AT4G18010.1
Gene Type
Coding gene
Location
4 : 9991194-9994099 : negative

Family Information

Homologous gene family
HOM02SEM000271
(112 genes in 26 species)
specific family

Descriptions

Curated Summary
Encodes an inositol polyphosphate 5-phosphatase that appears to have Type I activity. It can dephosphorylate IP3(inositol(1,4,5)P3) and IP4 (inositol(1,3,4,5)P4), but it does not appear to be active against phosphatidylinositol 4,5 bisphosphate. Overexpression of this gene renders plants insensitive to ABA in germination and growth assays.
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Identifiers

Type Value
uniprotQ9FUR2
aliasmyo-inositol polyphosphate 5-phosphatase 2
aliasAT5PTASE2
aliasIP5PII
aliasINOSITOL(1,4,5)P3 5-PHOSPHATASE II
alias5PTASE2

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0046856
IDA
Gene Ontologyphosphatidylinositol dephosphorylation1 2
GO:0046856
IEA
InterProphosphatidylinositol dephosphorylation
GO:0090351
IMP
Gene Ontologyseedling development3 4
GO:0046855
IDA, IMP
Gene Ontologyinositol phosphate dephosphorylation3 4 5 6
GO:0032957
IMP
Gene Ontologyinositol trisphosphate metabolic process3 4 5 6
GO:0009845
IMP
Gene Ontologyseed germination3 4
GO:0009737
IMP
Gene Ontologyresponse to abscisic acid5 6
GO:0032970
IEA
PLAZA Integrative Orthologyregulation of actin filament-based process FBgn0023508
GO:0097435
IEA
PLAZA Integrative Orthologysupramolecular fiber organization ENSG00000165458
GO:0002429
IEA
PLAZA Integrative Orthologyimmune response-activating cell surface receptor signaling pathway ENSG00000168918
GO:0051234
IEA
PLAZA Integrative Orthologyestablishment of localization ENSG00000165458
GO:0048870
IEA
PLAZA Integrative Orthologycell motility ENSG00000168918
GO:0110020
IEA
PLAZA Integrative Orthologyregulation of actomyosin structure organization FBgn0023508
GO:0008654
IEA
PLAZA Integrative Orthologyphospholipid biosynthetic process ENSG00000168918
GO:0032187
IEA
PLAZA Integrative Orthologyactomyosin contractile ring localization FBgn0023508
GO:0061024
IEA
PLAZA Integrative Orthologymembrane organization ENSG00000122126
GO:0032506
IEA
PLAZA Integrative Orthologycytokinetic process FBgn0023508
GO:0009058
IEA
PLAZA Integrative Orthologybiosynthetic process ENSG00000168918
GO:0000910
IEA
PLAZA Integrative Orthologycytokinesis FBgn0023508
GO:0000912
IEA
PLAZA Integrative Orthologyassembly of actomyosin apparatus involved in cytokinesis FBgn0023508
GO:0033043
IEA
PLAZA Integrative Orthologyregulation of organelle organization FBgn0023508
GO:0000915
IEA
PLAZA Integrative Orthologyactomyosin contractile ring assembly FBgn0023508
GO:0051336
IEA
PLAZA Integrative Orthologyregulation of hydrolase activity ENSG00000122126
GO:0120031
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection assembly ENSG00000122126
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis ENSG00000165458
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization ENSG00000165458
GO:0006928
IEA
PLAZA Integrative Orthologymovement of cell or subcellular component ENSG00000168918
GO:0048731
IEA
PLAZA Integrative Orthologysystem development ENSG00000165458
GO:0009887
IEA
PLAZA Integrative Orthologyanimal organ morphogenesis ENSG00000165458
GO:0006810
IEA
PLAZA Integrative Orthologytransport ENSG00000165458
GO:0044249
IEA
PLAZA Integrative Orthologycellular biosynthetic process ENSG00000168918
GO:0060271
IEA
PLAZA Integrative Orthologycilium assembly ENSG00000122126
GO:0070887
IEA
PLAZA Integrative Orthologycellular response to chemical stimulus ENSG00000168918
GO:2000431
IEA
PLAZA Integrative Orthologyregulation of cytokinesis, actomyosin contractile ring assembly FBgn0023508
GO:0098657
IEA
PLAZA Integrative Orthologyimport into cell ENSG00000165458
GO:0002684
IEA
PLAZA Integrative Orthologypositive regulation of immune system process ENSG00000168918
GO:0002682
IEA
PLAZA Integrative Orthologyregulation of immune system process ENSG00000168918
GO:0022607
IEA
PLAZA Integrative Orthologycellular component assembly ENSG00000122126
GO:0120036
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection organization ENSG00000122126
GO:0051716
IEA
PLAZA Integrative Orthologycellular response to stimulus SPBC577.13
GO:0008610
IEA
PLAZA Integrative Orthologylipid biosynthetic process ENSG00000168918
GO:0050852
IEA
PLAZA Integrative OrthologyT cell receptor signaling pathway ENSG00000168918
GO:0016477
IEA
PLAZA Integrative Orthologycell migration ENSG00000168918
GO:0071310
IEA
PLAZA Integrative Orthologycellular response to organic substance ENSG00000168918
GO:0050851
IEA
PLAZA Integrative Orthologyantigen receptor-mediated signaling pathway ENSG00000168918
GO:0006661
IEA
PLAZA Integrative Orthologyphosphatidylinositol biosynthetic process ENSG00000168918
GO:0036075
IEA
PLAZA Integrative Orthologyreplacement ossification ENSG00000165458
GO:0040011
IEA
PLAZA Integrative Orthologylocomotion ENSG00000168918
GO:0032954
IEA
PLAZA Integrative Orthologyregulation of cytokinetic process FBgn0023508
GO:0043087
IEA
PLAZA Integrative Orthologyregulation of GTPase activity ENSG00000122126
GO:0046474
IEA
PLAZA Integrative Orthologyglycerophospholipid biosynthetic process ENSG00000168918
GO:0051493
IEA
PLAZA Integrative Orthologyregulation of cytoskeleton organization FBgn0023508
GO:0002768
IEA
PLAZA Integrative Orthologyimmune response-regulating cell surface receptor signaling pathway ENSG00000168918
GO:0032956
IEA
PLAZA Integrative Orthologyregulation of actin cytoskeleton organization FBgn0023508
GO:0002764
IEA
PLAZA Integrative Orthologyimmune response-regulating signaling pathway ENSG00000168918
GO:0009966
IEA
PLAZA Integrative Orthologyregulation of signal transduction ENSG00000122126
GO:0045017
IEA
PLAZA Integrative Orthologyglycerolipid biosynthetic process ENSG00000168918
GO:0051128
IEA
PLAZA Integrative Orthologyregulation of cellular component organization FBgn0023508
GO:0035556
IEA
PLAZA Integrative Orthologyintracellular signal transduction SPBC577.13
GO:0002757
IEA
PLAZA Integrative Orthologyimmune response-activating signal transduction ENSG00000168918
GO:0048518
IEA
PLAZA Integrative Orthologypositive regulation of biological process ENSG00000168918
GO:0048513
IEA
PLAZA Integrative Orthologyanimal organ development ENSG00000165458
GO:0044837
IEA
PLAZA Integrative Orthologyactomyosin contractile ring organization FBgn0023508
GO:0010564
IEA
PLAZA Integrative Orthologyregulation of cell cycle process FBgn0023508
GO:0030036
IEA
PLAZA Integrative Orthologyactin cytoskeleton organization ENSG00000165458
GO:0050789
IEA
PLAZA Integrative Orthologyregulation of biological process SPBC577.13
GO:0090407
IEA
PLAZA Integrative Orthologyorganophosphate biosynthetic process ENSG00000168918
GO:0071345
IEA
PLAZA Integrative Orthologycellular response to cytokine stimulus ENSG00000168918
GO:0007049
IEA
PLAZA Integrative Orthologycell cycle FBgn0023508
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization ENSG00000165458
GO:0007166
IEA
PLAZA Integrative Orthologycell surface receptor signaling pathway ENSG00000168918
GO:1901576
IEA
PLAZA Integrative Orthologyorganic substance biosynthetic process ENSG00000168918
GO:0007165
IEA
PLAZA Integrative Orthologysignal transduction SPBC577.13
GO:0050776
IEA
PLAZA Integrative Orthologyregulation of immune response ENSG00000168918
GO:0050778
IEA
PLAZA Integrative Orthologypositive regulation of immune response ENSG00000168918
GO:0032465
IEA
PLAZA Integrative Orthologyregulation of cytokinesis FBgn0023508
GO:0044782
IEA
PLAZA Integrative Orthologycilium organization ENSG00000122126
GO:0048583
IEA
PLAZA Integrative Orthologyregulation of response to stimulus ENSG00000168918
GO:0048584
IEA
PLAZA Integrative Orthologypositive regulation of response to stimulus ENSG00000168918
GO:0060348
IEA
PLAZA Integrative Orthologybone development ENSG00000165458
GO:0007155
IEA
PLAZA Integrative Orthologycell adhesion ENSG00000165458
GO:0060349
IEA
PLAZA Integrative Orthologybone morphogenesis ENSG00000165458
GO:1902531
IEA
PLAZA Integrative Orthologyregulation of intracellular signal transduction ENSG00000122126
GO:0007154
IEA
PLAZA Integrative Orthologycell communication SPBC577.13
GO:0034097
IEA
PLAZA Integrative Orthologyresponse to cytokine ENSG00000168918
GO:0051056
IEA
PLAZA Integrative Orthologyregulation of small GTPase mediated signal transduction ENSG00000122126
GO:0051179
IEA
PLAZA Integrative Orthologylocalization ENSG00000168918
GO:0006897
IEA
PLAZA Integrative Orthologyendocytosis ENSG00000165458
GO:0031032
IEA
PLAZA Integrative Orthologyactomyosin structure organization FBgn0023508
GO:0061640
IEA
PLAZA Integrative Orthologycytoskeleton-dependent cytokinesis FBgn0023508
GO:0051726
IEA
PLAZA Integrative Orthologyregulation of cell cycle FBgn0023508
GO:0001503
IEA
PLAZA Integrative Orthologyossification ENSG00000165458
GO:0044087
IEA
PLAZA Integrative Orthologyregulation of cellular component biogenesis FBgn0023508
GO:0001501
IEA
PLAZA Integrative Orthologyskeletal system development ENSG00000165458
GO:0044085
IEA
PLAZA Integrative Orthologycellular component biogenesis ENSG00000122126
GO:0030865
IEA
PLAZA Integrative Orthologycortical cytoskeleton organization FBgn0023508
GO:0030866
IEA
PLAZA Integrative Orthologycortical actin cytoskeleton organization FBgn0023508
GO:1903047
IEA
PLAZA Integrative Orthologymitotic cell cycle process FBgn0023508
GO:0070925
IEA
PLAZA Integrative Orthologyorganelle assembly ENSG00000122126
GO:0036214
IEA
PLAZA Integrative Orthologycontractile ring localization FBgn0023508
GO:0010646
IEA
PLAZA Integrative Orthologyregulation of cell communication ENSG00000122126
GO:0050900
IEA
PLAZA Integrative Orthologyleukocyte migration ENSG00000168918
GO:0051674
IEA
PLAZA Integrative Orthologylocalization of cell ENSG00000168918
GO:0022610
IEA
PLAZA Integrative Orthologybiological adhesion ENSG00000165458
GO:0048705
IEA
PLAZA Integrative Orthologyskeletal system morphogenesis ENSG00000165458
GO:0000281
IEA
PLAZA Integrative Orthologymitotic cytokinesis FBgn0023508
GO:0019221
IEA
PLAZA Integrative Orthologycytokine-mediated signaling pathway ENSG00000168918
GO:0016192
IEA
PLAZA Integrative Orthologyvesicle-mediated transport ENSG00000165458
GO:0051302
IEA
PLAZA Integrative Orthologyregulation of cell division FBgn0023508
GO:0051301
IEA
PLAZA Integrative Orthologycell division FBgn0023508
GO:0000278
IEA
PLAZA Integrative Orthologymitotic cell cycle FBgn0023508
GO:0048017
IEA
PLAZA Integrative Orthologyinositol lipid-mediated signaling SPBC577.13
GO:0009653
IEA
PLAZA Integrative Orthologyanatomical structure morphogenesis ENSG00000165458
GO:0001958
IEA
PLAZA Integrative Orthologyendochondral ossification ENSG00000165458
GO:0023052
IEA
PLAZA Integrative Orthologysignaling SPBC577.13
GO:0023051
IEA
PLAZA Integrative Orthologyregulation of signaling ENSG00000122126
GO:0065009
IEA
PLAZA Integrative Orthologyregulation of molecular function ENSG00000122126
GO:0002376
IEA
PLAZA Integrative Orthologyimmune system process ENSG00000168918
GO:0002253
IEA
PLAZA Integrative Orthologyactivation of immune response ENSG00000168918
GO:0060350
IEA
PLAZA Integrative Orthologyendochondral bone morphogenesis ENSG00000165458
GO:0007264
IEA
PLAZA Integrative Orthologysmall GTPase mediated signal transduction ENSG00000122126
GO:0065007
IEA
PLAZA Integrative Orthologybiological regulation SPBC577.13
GO:0050790
IEA
PLAZA Integrative Orthologyregulation of catalytic activity ENSG00000122126
GO:0006955
IEA
PLAZA Integrative Orthologyimmune response ENSG00000168918
GO:0050794
IEA
PLAZA Integrative Orthologyregulation of cellular process SPBC577.13
GO:0030029
IEA
PLAZA Integrative Orthologyactin filament-based process ENSG00000165458
GO:0007015
IEA
PLAZA Integrative Orthologyactin filament organization ENSG00000165458
GO:0022402
IEA
PLAZA Integrative Orthologycell cycle process FBgn0023508
GO:0030030
IEA
PLAZA Integrative Orthologycell projection organization ENSG00000122126
GO:0030031
IEA
PLAZA Integrative Orthologycell projection assembly ENSG00000122126
GO:0007010
IEA
PLAZA Integrative Orthologycytoskeleton organization ENSG00000165458

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0034485
IDA
Gene Ontologyphosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity1 2
GO:0004439
IDA
Gene Ontologyphosphatidylinositol-4,5-bisphosphate 5-phosphatase activity1 2
GO:0004445
IDA
ISS
Gene Ontologyinositol-polyphosphate 5-phosphatase activity5 6 7
GO:0019899
IEA
PLAZA Integrative Orthologyenzyme binding ENSG00000122126
GO:0017016
IEA
PLAZA Integrative OrthologyRas GTPase binding ENSG00000122126
GO:0030695
IEA
PLAZA Integrative OrthologyGTPase regulator activity ENSG00000122126
GO:0052659
IEA
PLAZA Integrative Orthologyinositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity ENSG00000168918
GO:0052658
IEA
PLAZA Integrative Orthologyinositol-1,4,5-trisphosphate 5-phosphatase activity ENSG00000122126
GO:0098772
IEA
PLAZA Integrative Orthologymolecular function regulator ENSG00000122126
GO:0051020
IEA
PLAZA Integrative OrthologyGTPase binding ENSG00000122126
GO:0008047
IEA
PLAZA Integrative Orthologyenzyme activator activity ENSG00000122126
GO:0005488
IEA
PLAZA Integrative Orthologybinding ENSG00000168918
GO:0034596
IEA
PLAZA Integrative Orthologyphosphatidylinositol phosphate 4-phosphatase activity ENSG00000122126
GO:0016314
IEA
PLAZA Integrative Orthologyphosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity ENSG00000168918
GO:0060589
IEA
PLAZA Integrative Orthologynucleoside-triphosphatase regulator activity ENSG00000122126
GO:0005096
IEA
PLAZA Integrative OrthologyGTPase activator activity ENSG00000122126
GO:0031267
IEA
PLAZA Integrative Orthologysmall GTPase binding ENSG00000122126
GO:0106018
IEA
PLAZA Integrative Orthologyphosphatidylinositol-3,5-bisphosphate phosphatase activity ENSG00000122126
GO:0030234
IEA
PLAZA Integrative Orthologyenzyme regulator activity ENSG00000122126
GO:0042169
IEA
PLAZA Integrative OrthologySH2 domain binding ENSG00000165458
GO:0043813
IEA
PLAZA Integrative Orthologyphosphatidylinositol-3,5-bisphosphate 5-phosphatase activity ENSG00000122126
GO:0017048
IEA
PLAZA Integrative OrthologyRho GTPase binding ENSG00000122126
GO:0005515
IEA
PLAZA Integrative Orthologyprotein binding ENSG00000168918
GO:0052743
IEA
PLAZA Integrative Orthologyinositol tetrakisphosphate phosphatase activity ENSG00000168918
GO:0019904
IEA
PLAZA Integrative Orthologyprotein domain specific binding ENSG00000165458
GO:0048365
IEA
PLAZA Integrative OrthologyRac GTPase binding ENSG00000122126

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
ISM
Gene Ontologycytoplasm8
GO:0055037
IEA
PLAZA Integrative Orthologyrecycling endosome FBgn0023508
GO:0016020
IEA
PLAZA Integrative Orthologymembrane ENSG00000122126
GO:0031410
IEA
PLAZA Integrative Orthologycytoplasmic vesicle ENSG00000122126
GO:0005929
IEA
PLAZA Integrative Orthologycilium ENSG00000122126
GO:0005802
IEA
PLAZA Integrative Orthologytrans-Golgi network ENSG00000122126
GO:0042995
IEA
PLAZA Integrative Orthologycell projection ENSG00000122126
GO:0097458
IEA
PLAZA Integrative Orthologyneuron part ENSG00000122126
GO:0098791
IEA
PLAZA Integrative OrthologyGolgi subcompartment ENSG00000122126
GO:0120025
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection ENSG00000122126
GO:0005829
IEA
PLAZA Integrative Orthologycytosol SPAC9G1.10c
GO:0120038
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection part ENSG00000122126
GO:1903561
IEA
PLAZA Integrative Orthologyextracellular vesicle ENSG00000122126
GO:0005576
IEA
PLAZA Integrative Orthologyextracellular region ENSG00000122126
GO:0032153
IEA
PLAZA Integrative Orthologycell division site SPAC9G1.10c
GO:0031984
IEA
PLAZA Integrative Orthologyorganelle subcompartment ENSG00000122126
GO:0031982
IEA
PLAZA Integrative Orthologyvesicle ENSG00000122126
GO:0012505
IEA
PLAZA Integrative Orthologyendomembrane system ENSG00000165458
GO:0044422
IEA
PLAZA Integrative Orthologyorganelle part ENSG00000122126
GO:0044421
IEA
PLAZA Integrative Orthologyextracellular region part ENSG00000122126
GO:0097708
IEA
PLAZA Integrative Orthologyintracellular vesicle ENSG00000122126
GO:0005768
IEA
PLAZA Integrative Orthologyendosome ENSG00000122126
GO:0005769
IEA
PLAZA Integrative Orthologyearly endosome ENSG00000122126
GO:0005770
IEA
PLAZA Integrative Orthologylate endosome FBgn0023508
GO:0097733
IEA
PLAZA Integrative Orthologyphotoreceptor cell cilium ENSG00000122126
GO:0097730
IEA
PLAZA Integrative Orthologynon-motile cilium ENSG00000122126
GO:0097731
IEA
PLAZA Integrative Orthology9+0 non-motile cilium ENSG00000122126
GO:0051286
IEA
PLAZA Integrative Orthologycell tip SPAC9G1.10c
GO:0001750
IEA
PLAZA Integrative Orthologyphotoreceptor outer segment ENSG00000122126
GO:0005798
IEA
PLAZA Integrative OrthologyGolgi-associated vesicle ENSG00000122126
GO:0005795
IEA
PLAZA Integrative OrthologyGolgi stack ENSG00000122126
GO:0005794
IEA
PLAZA Integrative OrthologyGolgi apparatus ENSG00000165458
GO:0071944
IEA
PLAZA Integrative Orthologycell periphery ENSG00000122126
GO:0005615
IEA
PLAZA Integrative Orthologyextracellular space ENSG00000122126
GO:0044463
IEA
PLAZA Integrative Orthologycell projection part ENSG00000122126
GO:0070062
IEA
PLAZA Integrative Orthologyextracellular exosome ENSG00000122126
GO:0043005
IEA
PLAZA Integrative Orthologyneuron projection ENSG00000122126
GO:0030135
IEA
PLAZA Integrative Orthologycoated vesicle ENSG00000122126
GO:0030136
IEA
PLAZA Integrative Orthologyclathrin-coated vesicle ENSG00000122126
GO:0005634
IEA
PLAZA Integrative Orthologynucleus ENSG00000122126
GO:0005886
IEA
PLAZA Integrative Orthologyplasma membrane ENSG00000122126
GO:0044446
IEA
PLAZA Integrative Orthologyintracellular organelle part ENSG00000122126
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part SPAC9G1.10c
GO:0043230
IEA
PLAZA Integrative Orthologyextracellular organelle ENSG00000122126
GO:0044441
IEA
PLAZA Integrative Orthologyciliary part ENSG00000122126
GO:0043231
IEA
PLAZA Integrative Orthologyintracellular membrane-bounded organelle ENSG00000165458
GO:0043227
IEA
PLAZA Integrative Orthologymembrane-bounded organelle ENSG00000165458
GO:0043226
IEA
PLAZA Integrative Orthologyorganelle ENSG00000165458
GO:0044431
IEA
PLAZA Integrative OrthologyGolgi apparatus part ENSG00000122126
GO:0043229
IEA
PLAZA Integrative Orthologyintracellular organelle ENSG00000165458

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR005135Endonuclease/exonuclease/phosphatase
IPR000300Inositol polyphosphate-related phosphatase

No MapMan annotations defined for this gene.
No Kegg annotations defined for this gene.
No chloroplast target sequence found.