Gene: AT3G12990 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT3G12990
Transcript Identifier
AT3G12990.1
Gene Type
Coding gene
Location
3 : 4156345-4157842 : positive

Family Information

Homologous gene family
HOM02SEM001416
(40 genes in 25 species)
specific family

Descriptions

Description
ribonuclease PH45A
Curated Summary
Encodes a 3'-5' exoribonuclease, partially redundant with CER7. Involved in epicuticular wax biosynthesis.
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Identifiers

Type Value
uniprotQ9LDM2
aliasRRP45a

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006396
ISS
Gene OntologyRNA processing1
GO:0006396
IEA
InterProRNA processing
GO:0010025
IGI
Gene Ontologywax biosynthetic process2 3
GO:0031126
IEA
PLAZA Integrative OrthologysnoRNA 3'-end processing YDR280W
GO:0031125
IEA
PLAZA Integrative OrthologyrRNA 3'-end processing YDR280W
GO:0050789
IEA
PLAZA Integrative Orthologyregulation of biological process SPCC757.08
GO:0034476
IEA
PLAZA Integrative OrthologyU5 snRNA 3'-end processing YDR280W
GO:0031123
IEA
PLAZA Integrative OrthologyRNA 3'-end processing YDR280W
GO:0010605
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule metabolic process SPCC757.08
GO:0070651
IEA
PLAZA Integrative Orthologynonfunctional rRNA decay YDR280W
GO:0010608
IEA
PLAZA Integrative Orthologyposttranscriptional regulation of gene expression ENSG00000123737
GO:0044270
IEA
PLAZA Integrative Orthologycellular nitrogen compound catabolic process SPCC757.08
GO:1901575
IEA
PLAZA Integrative Orthologyorganic substance catabolic process SPCC757.08
GO:0044265
IEA
PLAZA Integrative Orthologycellular macromolecule catabolic process SPCC757.08
GO:0044260
IEA
PLAZA Integrative Orthologycellular macromolecule metabolic process SPCC757.08
GO:0009056
IEA
PLAZA Integrative Orthologycatabolic process SPCC757.08
GO:0009057
IEA
PLAZA Integrative Orthologymacromolecule catabolic process SPCC757.08
GO:0016049
IEA
PLAZA Integrative Orthologycell growth ENSG00000123737
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis YDR280W
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization ENSG00000123737
GO:0070478
IEA
PLAZA Integrative Orthologynuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay YDR280W
GO:0010468
IEA
PLAZA Integrative Orthologyregulation of gene expression SPCC757.08
GO:0034655
IEA
PLAZA Integrative Orthologynucleobase-containing compound catabolic process SPCC757.08
GO:0071047
IEA
PLAZA Integrative Orthologypolyadenylation-dependent mRNA catabolic process YDR280W
GO:0071046
IEA
PLAZA Integrative Orthologynuclear polyadenylation-dependent ncRNA catabolic process YDR280W
GO:0010629
IEA
PLAZA Integrative Orthologynegative regulation of gene expression SPCC757.08
GO:0071042
IEA
PLAZA Integrative Orthologynuclear polyadenylation-dependent mRNA catabolic process YDR280W
GO:0044248
IEA
PLAZA Integrative Orthologycellular catabolic process SPCC757.08
GO:0046700
IEA
PLAZA Integrative Orthologyheterocycle catabolic process SPCC757.08
GO:0034660
IEA
PLAZA Integrative OrthologyncRNA metabolic process YDR280W
GO:0034661
IEA
PLAZA Integrative OrthologyncRNA catabolic process YDR280W
GO:0090305
IEA
PLAZA Integrative Orthologynucleic acid phosphodiester bond hydrolysis YDR280W
GO:0034427
IEA
PLAZA Integrative Orthologynuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' YDR280W
GO:0071051
IEA
PLAZA Integrative Orthologypolyadenylation-dependent snoRNA 3'-end processing YDR280W
GO:0044085
IEA
PLAZA Integrative Orthologycellular component biogenesis YDR280W
GO:0070481
IEA
PLAZA Integrative Orthologynuclear-transcribed mRNA catabolic process, non-stop decay YDR280W
GO:0006401
IEA
PLAZA Integrative OrthologyRNA catabolic process SPCC757.08
GO:0006402
IEA
PLAZA Integrative OrthologymRNA catabolic process SPCC757.08
GO:0051171
IEA
PLAZA Integrative Orthologyregulation of nitrogen compound metabolic process ENSG00000123737
GO:0006364
IEA
PLAZA Integrative OrthologyrRNA processing YDR280W
GO:0043144
IEA
PLAZA Integrative OrthologysnoRNA processing YDR280W
GO:0061013
IEA
PLAZA Integrative Orthologyregulation of mRNA catabolic process ENSG00000123737
GO:0019439
IEA
PLAZA Integrative Orthologyaromatic compound catabolic process SPCC757.08
GO:0031323
IEA
PLAZA Integrative Orthologyregulation of cellular metabolic process ENSG00000123737
GO:0080090
IEA
PLAZA Integrative Orthologyregulation of primary metabolic process ENSG00000123737
GO:0071027
IEA
PLAZA Integrative Orthologynuclear RNA surveillance SPCC757.08
GO:0071029
IEA
PLAZA Integrative Orthologynuclear ncRNA surveillance YDR280W
GO:0071028
IEA
PLAZA Integrative Orthologynuclear mRNA surveillance SPCC757.08
GO:0000291
IEA
PLAZA Integrative Orthologynuclear-transcribed mRNA catabolic process, exonucleolytic YDR280W
GO:0071025
IEA
PLAZA Integrative OrthologyRNA surveillance SPCC757.08
GO:0016180
IEA
PLAZA Integrative OrthologysnRNA processing YDR280W
GO:0031329
IEA
PLAZA Integrative Orthologyregulation of cellular catabolic process ENSG00000123737
GO:0000288
IEA
PLAZA Integrative Orthologynuclear-transcribed mRNA catabolic process, deadenylation-dependent decay YDR280W
GO:0022613
IEA
PLAZA Integrative Orthologyribonucleoprotein complex biogenesis YDR280W
GO:0006399
IEA
PLAZA Integrative OrthologytRNA metabolic process YDR280W
GO:1903311
IEA
PLAZA Integrative Orthologyregulation of mRNA metabolic process ENSG00000123737
GO:0060255
IEA
PLAZA Integrative Orthologyregulation of macromolecule metabolic process SPCC757.08
GO:0071038
IEA
PLAZA Integrative Orthologynuclear polyadenylation-dependent tRNA catabolic process YDR280W
GO:0016078
IEA
PLAZA Integrative OrthologytRNA catabolic process YDR280W
GO:0019222
IEA
PLAZA Integrative Orthologyregulation of metabolic process SPCC757.08
GO:0016075
IEA
PLAZA Integrative OrthologyrRNA catabolic process YDR280W
GO:0016074
IEA
PLAZA Integrative OrthologysnoRNA metabolic process YDR280W
GO:0016073
IEA
PLAZA Integrative OrthologysnRNA metabolic process YDR280W
GO:0071035
IEA
PLAZA Integrative Orthologynuclear polyadenylation-dependent rRNA catabolic process YDR280W
GO:0016072
IEA
PLAZA Integrative OrthologyrRNA metabolic process YDR280W
GO:0016071
IEA
PLAZA Integrative OrthologymRNA metabolic process SPCC757.08
GO:0043487
IEA
PLAZA Integrative Orthologyregulation of RNA stability ENSG00000123737
GO:0009894
IEA
PLAZA Integrative Orthologyregulation of catabolic process ENSG00000123737
GO:0043488
IEA
PLAZA Integrative Orthologyregulation of mRNA stability ENSG00000123737
GO:0043928
IEA
PLAZA Integrative Orthologyexonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay YDR280W
GO:0000956
IEA
PLAZA Integrative Orthologynuclear-transcribed mRNA catabolic process SPCC757.08
GO:0009892
IEA
PLAZA Integrative Orthologynegative regulation of metabolic process SPCC757.08
GO:1901361
IEA
PLAZA Integrative Orthologyorganic cyclic compound catabolic process SPCC757.08
GO:0019219
IEA
PLAZA Integrative Orthologyregulation of nucleobase-containing compound metabolic process ENSG00000123737
GO:0051252
IEA
PLAZA Integrative Orthologyregulation of RNA metabolic process ENSG00000123737
GO:0001558
IEA
PLAZA Integrative Orthologyregulation of cell growth ENSG00000123737
GO:0043634
IEA
PLAZA Integrative Orthologypolyadenylation-dependent ncRNA catabolic process YDR280W
GO:0040007
IEA
PLAZA Integrative Orthologygrowth ENSG00000123737
GO:0040008
IEA
PLAZA Integrative Orthologyregulation of growth ENSG00000123737
GO:0043632
IEA
PLAZA Integrative Orthologymodification-dependent macromolecule catabolic process YDR280W
GO:0000466
IEA
PLAZA Integrative Orthologymaturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) YDR280W
GO:0043633
IEA
PLAZA Integrative Orthologypolyadenylation-dependent RNA catabolic process YDR280W
GO:0000467
IEA
PLAZA Integrative Orthologyexonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) YDR280W
GO:0000469
IEA
PLAZA Integrative Orthologycleavage involved in rRNA processing YDR280W
GO:0090501
IEA
PLAZA Integrative OrthologyRNA phosphodiester bond hydrolysis YDR280W
GO:0065008
IEA
PLAZA Integrative Orthologyregulation of biological quality ENSG00000123737
GO:0090503
IEA
PLAZA Integrative OrthologyRNA phosphodiester bond hydrolysis, exonucleolytic YDR280W
GO:0065007
IEA
PLAZA Integrative Orthologybiological regulation SPCC757.08
GO:0051128
IEA
PLAZA Integrative Orthologyregulation of cellular component organization ENSG00000123737
GO:0048522
IEA
PLAZA Integrative Orthologypositive regulation of cellular process ENSG00000123737
GO:0000184
IEA
PLAZA Integrative Orthologynuclear-transcribed mRNA catabolic process, nonsense-mediated decay YDR280W
GO:0050794
IEA
PLAZA Integrative Orthologyregulation of cellular process ENSG00000123737
GO:0000460
IEA
PLAZA Integrative Orthologymaturation of 5.8S rRNA YDR280W
GO:0030307
IEA
PLAZA Integrative Orthologypositive regulation of cell growth ENSG00000123737
GO:0048518
IEA
PLAZA Integrative Orthologypositive regulation of biological process ENSG00000123737
GO:0048519
IEA
PLAZA Integrative Orthologynegative regulation of biological process SPCC757.08
GO:0000459
IEA
PLAZA Integrative Orthologyexonucleolytic trimming involved in rRNA processing YDR280W
GO:0042254
IEA
PLAZA Integrative Orthologyribosome biogenesis YDR280W
GO:0034472
IEA
PLAZA Integrative OrthologysnRNA 3'-end processing YDR280W
GO:0034473
IEA
PLAZA Integrative OrthologyU1 snRNA 3'-end processing YDR280W
GO:0034475
IEA
PLAZA Integrative OrthologyU4 snRNA 3'-end processing YDR280W
GO:0043628
IEA
PLAZA Integrative OrthologyncRNA 3'-end processing YDR280W
GO:0045927
IEA
PLAZA Integrative Orthologypositive regulation of growth ENSG00000123737
GO:0034470
IEA
PLAZA Integrative OrthologyncRNA processing YDR280W

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000175
IGI
ISS
Gene Ontology3'-5'-exoribonuclease activity1 2 3
GO:0003723
ISS
Gene OntologyRNA binding1
GO:0017091
IEA
PLAZA Integrative OrthologyAU-rich element binding ENSG00000123737
GO:0005515
IEA
PLAZA Integrative Orthologyprotein binding ENSG00000123737

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000178
IEA
InterProexosome (RNase complex)
GO:0005737
IDA
ISM
Gene Ontologycytoplasm2 3 4
GO:0005634
IDA
Gene Ontologynucleus2 3
GO:0070013
IEA
PLAZA Integrative Orthologyintracellular organelle lumen YDR280W
GO:0044422
IEA
PLAZA Integrative Orthologyorganelle part YDR280W
GO:0044421
IEA
PLAZA Integrative Orthologyextracellular region part ENSG00000123737
GO:0044428
IEA
PLAZA Integrative Orthologynuclear part YDR280W
GO:0005654
IEA
PLAZA Integrative Orthologynucleoplasm ENSG00000123737
GO:0005829
IEA
PLAZA Integrative Orthologycytosol SPCC757.08
GO:1903561
IEA
PLAZA Integrative Orthologyextracellular vesicle ENSG00000123737
GO:0005615
IEA
PLAZA Integrative Orthologyextracellular space ENSG00000123737
GO:0000176
IEA
PLAZA Integrative Orthologynuclear exosome (RNase complex) YDR280W
GO:0000177
IEA
PLAZA Integrative Orthologycytoplasmic exosome (RNase complex) YDR280W
GO:0031974
IEA
PLAZA Integrative Orthologymembrane-enclosed lumen YDR280W
GO:0070062
IEA
PLAZA Integrative Orthologyextracellular exosome ENSG00000123737
GO:0005576
IEA
PLAZA Integrative Orthologyextracellular region ENSG00000123737
GO:0005730
IEA
PLAZA Integrative Orthologynucleolus YDR280W
GO:0005694
IEA
PLAZA Integrative Orthologychromosome ENSG00000123737
GO:0031982
IEA
PLAZA Integrative Orthologyvesicle ENSG00000123737
GO:0031981
IEA
PLAZA Integrative Orthologynuclear lumen YDR280W
GO:0044446
IEA
PLAZA Integrative Orthologyintracellular organelle part YDR280W
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part SPCC757.08
GO:0000228
IEA
PLAZA Integrative Orthologynuclear chromosome ENSG00000123737
GO:0043232
IEA
PLAZA Integrative Orthologyintracellular non-membrane-bounded organelle YDR280W
GO:0043233
IEA
PLAZA Integrative Orthologyorganelle lumen YDR280W
GO:0043230
IEA
PLAZA Integrative Orthologyextracellular organelle ENSG00000123737
GO:0043228
IEA
PLAZA Integrative Orthologynon-membrane-bounded organelle YDR280W

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR033100Exosome complex component RRP45
IPR027408PNPase/RNase PH domain superfamily
IPR015847Exoribonuclease, phosphorolytic domain 2
IPR001247Exoribonuclease, phosphorolytic domain 1
IPR020568Ribosomal protein S5 domain 2-type fold

No MapMan annotations defined for this gene.
KeggID Description
K12586RRP43, EXOSC8, OIP2; exosome complex component RRP43
K03678RRP45, EXOSC9; exosome complex component RRP45
K10397KIF6_9; kinesin family member 6/9
K12589RRP42, EXOSC7; exosome complex component RRP42
K12842SR140; U2-associated protein SR140
No chloroplast target sequence found.