Gene: AT2G37560 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT2G37560
Transcript Identifier
AT2G37560.1
Gene Type
Coding gene
Location
2 : 15759568-15761116 : positive

Family Information

Homologous gene family
HOM02SEM002644
(27 genes in 24 species)
specific family

Descriptions

Curated Summary
Origin Recognition Complex subunit 2. Involved in the initiation of DNA replication. Regulated transcriptionally during cell cycle, peaking at G1/S-phase. Target of E2F/DF family of transcription factors. Interacts strongly with all ORC subunits.
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Identifiers

Type Value
uniprotQ38899
aliasATORC2
aliasORIGIN RECOGNITION COMPLEX SECOND LARGEST SUBUNIT 2
aliasorigin recognition complex second largest subunit 2
aliasORC2

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006260
ISS
Gene OntologyDNA replication1 2
GO:0006260
IEA
InterProDNA replication
GO:0007010
IEA
PLAZA Integrative Orthologycytoskeleton organization FBgn0015270
GO:0022402
IEA
PLAZA Integrative Orthologycell cycle process SPBC685.09
GO:1902315
IEA
PLAZA Integrative Orthologynuclear cell cycle DNA replication initiation SPBC685.09
GO:1902679
IEA
PLAZA Integrative Orthologynegative regulation of RNA biosynthetic process YBR060C
GO:0007017
IEA
PLAZA Integrative Orthologymicrotubule-based process FBgn0015270
GO:0030703
IEA
PLAZA Integrative Orthologyeggshell formation FBgn0015270
GO:0050794
IEA
PLAZA Integrative Orthologyregulation of cellular process YBR060C
GO:0045892
IEA
PLAZA Integrative Orthologynegative regulation of transcription, DNA-templated YBR060C
GO:0030707
IEA
PLAZA Integrative Orthologyovarian follicle cell development FBgn0015270
GO:0034622
IEA
PLAZA Integrative Orthologycellular protein-containing complex assembly YBR060C
GO:2000113
IEA
PLAZA Integrative Orthologynegative regulation of cellular macromolecule biosynthetic process YBR060C
GO:2000112
IEA
PLAZA Integrative Orthologyregulation of cellular macromolecule biosynthetic process YBR060C
GO:0065007
IEA
PLAZA Integrative Orthologybiological regulation YBR060C
GO:0065003
IEA
PLAZA Integrative Orthologyprotein-containing complex assembly YBR060C
GO:0065004
IEA
PLAZA Integrative Orthologyprotein-DNA complex assembly YBR060C
GO:0030261
IEA
PLAZA Integrative Orthologychromosome condensation FBgn0015270
GO:0018022
IEA
PLAZA Integrative Orthologypeptidyl-lysine methylation YBR060C
GO:0000070
IEA
PLAZA Integrative Orthologymitotic sister chromatid segregation FBgn0015270
GO:0097659
IEA
PLAZA Integrative Orthologynucleic acid-templated transcription YBR060C
GO:0019219
IEA
PLAZA Integrative Orthologyregulation of nucleobase-containing compound metabolic process YBR060C
GO:0009892
IEA
PLAZA Integrative Orthologynegative regulation of metabolic process YBR060C
GO:1901362
IEA
PLAZA Integrative Orthologyorganic cyclic compound biosynthetic process YBR060C
GO:0006261
IEA
PLAZA Integrative OrthologyDNA-dependent DNA replication SPBC685.09
GO:0009890
IEA
PLAZA Integrative Orthologynegative regulation of biosynthetic process YBR060C
GO:0006267
IEA
PLAZA Integrative Orthologypre-replicative complex assembly involved in nuclear cell cycle DNA replication YBR060C
GO:0009653
IEA
PLAZA Integrative Orthologyanatomical structure morphogenesis FBgn0015270
GO:0000278
IEA
PLAZA Integrative Orthologymitotic cell cycle SPBC685.09
GO:0016070
IEA
PLAZA Integrative OrthologyRNA metabolic process YBR060C
GO:0034968
IEA
PLAZA Integrative Orthologyhistone lysine methylation YBR060C
GO:0018130
IEA
PLAZA Integrative Orthologyheterocycle biosynthetic process YBR060C
GO:0000280
IEA
PLAZA Integrative Orthologynuclear division FBgn0015270
GO:0140014
IEA
PLAZA Integrative Orthologymitotic nuclear division FBgn0015270
GO:0019222
IEA
PLAZA Integrative Orthologyregulation of metabolic process YBR060C
GO:0006270
IEA
PLAZA Integrative OrthologyDNA replication initiation SPBC685.09
GO:0043933
IEA
PLAZA Integrative Orthologyprotein-containing complex subunit organization YBR060C
GO:0060255
IEA
PLAZA Integrative Orthologyregulation of macromolecule metabolic process YBR060C
GO:0006277
IEA
PLAZA Integrative OrthologyDNA amplification FBgn0015270
GO:0008213
IEA
PLAZA Integrative Orthologyprotein alkylation YBR060C
GO:0031327
IEA
PLAZA Integrative Orthologynegative regulation of cellular biosynthetic process YBR060C
GO:0032774
IEA
PLAZA Integrative OrthologyRNA biosynthetic process YBR060C
GO:0071824
IEA
PLAZA Integrative Orthologyprotein-DNA complex subunit organization YBR060C
GO:0031326
IEA
PLAZA Integrative Orthologyregulation of cellular biosynthetic process YBR060C
GO:0080090
IEA
PLAZA Integrative Orthologyregulation of primary metabolic process YBR060C
GO:0031323
IEA
PLAZA Integrative Orthologyregulation of cellular metabolic process YBR060C
GO:0031324
IEA
PLAZA Integrative Orthologynegative regulation of cellular metabolic process YBR060C
GO:0007292
IEA
PLAZA Integrative Orthologyfemale gamete generation FBgn0015270
GO:0016569
IEA
PLAZA Integrative Orthologycovalent chromatin modification YBR060C
GO:0007051
IEA
PLAZA Integrative Orthologyspindle organization FBgn0015270
GO:1903047
IEA
PLAZA Integrative Orthologymitotic cell cycle process SPBC685.09
GO:0007052
IEA
PLAZA Integrative Orthologymitotic spindle organization FBgn0015270
GO:0051172
IEA
PLAZA Integrative Orthologynegative regulation of nitrogen compound metabolic process YBR060C
GO:0007059
IEA
PLAZA Integrative Orthologychromosome segregation FBgn0015270
GO:0051171
IEA
PLAZA Integrative Orthologyregulation of nitrogen compound metabolic process YBR060C
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction FBgn0015270
GO:0044085
IEA
PLAZA Integrative Orthologycellular component biogenesis YBR060C
GO:0018193
IEA
PLAZA Integrative Orthologypeptidyl-amino acid modification YBR060C
GO:0016570
IEA
PLAZA Integrative Orthologyhistone modification YBR060C
GO:0016571
IEA
PLAZA Integrative Orthologyhistone methylation YBR060C
GO:0098813
IEA
PLAZA Integrative Orthologynuclear chromosome segregation FBgn0015270
GO:2001141
IEA
PLAZA Integrative Orthologyregulation of RNA biosynthetic process YBR060C
GO:0030855
IEA
PLAZA Integrative Orthologyepithelial cell differentiation FBgn0015270
GO:0044770
IEA
PLAZA Integrative Orthologycell cycle phase transition ENSG00000115942
GO:0010468
IEA
PLAZA Integrative Orthologyregulation of gene expression YBR060C
GO:0010467
IEA
PLAZA Integrative Orthologygene expression YBR060C
GO:0034654
IEA
PLAZA Integrative Orthologynucleobase-containing compound biosynthetic process YBR060C
GO:0019953
IEA
PLAZA Integrative Orthologysexual reproduction FBgn0015270
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development FBgn0015270
GO:0007399
IEA
PLAZA Integrative Orthologynervous system development FBgn0015270
GO:1901564
IEA
PLAZA Integrative Orthologyorganonitrogen compound metabolic process YBR060C
GO:0044772
IEA
PLAZA Integrative Orthologymitotic cell cycle phase transition ENSG00000115942
GO:0007276
IEA
PLAZA Integrative Orthologygamete generation FBgn0015270
GO:1903506
IEA
PLAZA Integrative Orthologyregulation of nucleic acid-templated transcription YBR060C
GO:1903507
IEA
PLAZA Integrative Orthologynegative regulation of nucleic acid-templated transcription YBR060C
GO:0000082
IEA
PLAZA Integrative OrthologyG1/S transition of mitotic cell cycle ENSG00000115942
GO:0010556
IEA
PLAZA Integrative Orthologyregulation of macromolecule biosynthetic process YBR060C
GO:0034401
IEA
PLAZA Integrative Orthologychromatin organization involved in regulation of transcription YBR060C
GO:0010558
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule biosynthetic process YBR060C
GO:0007281
IEA
PLAZA Integrative Orthologygerm cell development FBgn0015270
GO:0036388
IEA
PLAZA Integrative Orthologypre-replicative complex assembly YBR060C
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process FBgn0015270
GO:0044786
IEA
PLAZA Integrative Orthologycell cycle DNA replication SPBC685.09
GO:0048468
IEA
PLAZA Integrative Orthologycell development FBgn0015270
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization YBR060C
GO:0007049
IEA
PLAZA Integrative Orthologycell cycle SPBC685.09
GO:0022412
IEA
PLAZA Integrative Orthologycellular process involved in reproduction in multicellular organism FBgn0015270
GO:0048477
IEA
PLAZA Integrative Orthologyoogenesis FBgn0015270
GO:0030154
IEA
PLAZA Integrative Orthologycell differentiation FBgn0015270
GO:0071103
IEA
PLAZA Integrative OrthologyDNA conformation change FBgn0015270
GO:0050789
IEA
PLAZA Integrative Orthologyregulation of biological process YBR060C
GO:0033260
IEA
PLAZA Integrative Orthologynuclear DNA replication SPBC685.09
GO:0022008
IEA
PLAZA Integrative Orthologyneurogenesis FBgn0015270
GO:0006325
IEA
PLAZA Integrative Orthologychromatin organization YBR060C
GO:0048519
IEA
PLAZA Integrative Orthologynegative regulation of biological process YBR060C
GO:0006323
IEA
PLAZA Integrative OrthologyDNA packaging FBgn0015270
GO:0071897
IEA
PLAZA Integrative OrthologyDNA biosynthetic process FBgn0015270
GO:0045814
IEA
PLAZA Integrative Orthologynegative regulation of gene expression, epigenetic YBR060C
GO:0048646
IEA
PLAZA Integrative Orthologyanatomical structure formation involved in morphogenesis FBgn0015270
GO:0048523
IEA
PLAZA Integrative Orthologynegative regulation of cellular process YBR060C
GO:0000226
IEA
PLAZA Integrative Orthologymicrotubule cytoskeleton organization FBgn0015270
GO:0044843
IEA
PLAZA Integrative Orthologycell cycle G1/S phase transition ENSG00000115942
GO:0007304
IEA
PLAZA Integrative Orthologychorion-containing eggshell formation FBgn0015270
GO:0045934
IEA
PLAZA Integrative Orthologynegative regulation of nucleobase-containing compound metabolic process YBR060C
GO:0051253
IEA
PLAZA Integrative Orthologynegative regulation of RNA metabolic process YBR060C
GO:0051252
IEA
PLAZA Integrative Orthologyregulation of RNA metabolic process YBR060C
GO:0008283
IEA
PLAZA Integrative Orthologycell proliferation FBgn0015270
GO:1902299
IEA
PLAZA Integrative Orthologypre-replicative complex assembly involved in cell cycle DNA replication YBR060C
GO:0007076
IEA
PLAZA Integrative Orthologymitotic chromosome condensation FBgn0015270
GO:1902850
IEA
PLAZA Integrative Orthologymicrotubule cytoskeleton organization involved in mitosis FBgn0015270
GO:1902975
IEA
PLAZA Integrative Orthologymitotic DNA replication initiation SPBC685.09
GO:0002064
IEA
PLAZA Integrative Orthologyepithelial cell development FBgn0015270
GO:0002065
IEA
PLAZA Integrative Orthologycolumnar/cuboidal epithelial cell differentiation FBgn0015270
GO:0060429
IEA
PLAZA Integrative Orthologyepithelium development FBgn0015270
GO:0002066
IEA
PLAZA Integrative Orthologycolumnar/cuboidal epithelial cell development FBgn0015270
GO:1902969
IEA
PLAZA Integrative Orthologymitotic DNA replication SPBC685.09
GO:0051704
IEA
PLAZA Integrative Orthologymulti-organism process FBgn0015270
GO:1902292
IEA
PLAZA Integrative Orthologycell cycle DNA replication initiation SPBC685.09
GO:0016458
IEA
PLAZA Integrative Orthologygene silencing YBR060C
GO:0043412
IEA
PLAZA Integrative Orthologymacromolecule modification YBR060C
GO:0040029
IEA
PLAZA Integrative Orthologyregulation of gene expression, epigenetic YBR060C
GO:0043414
IEA
PLAZA Integrative Orthologymacromolecule methylation YBR060C
GO:0010927
IEA
PLAZA Integrative Orthologycellular component assembly involved in morphogenesis FBgn0015270
GO:0051276
IEA
PLAZA Integrative Orthologychromosome organization YBR060C
GO:0032259
IEA
PLAZA Integrative Orthologymethylation YBR060C
GO:0036211
IEA
PLAZA Integrative Orthologyprotein modification process YBR060C
GO:0000819
IEA
PLAZA Integrative Orthologysister chromatid segregation FBgn0015270
GO:0022607
IEA
PLAZA Integrative Orthologycellular component assembly YBR060C
GO:0006366
IEA
PLAZA Integrative Orthologytranscription by RNA polymerase II ENSG00000115942
GO:0048285
IEA
PLAZA Integrative Orthologyorganelle fission FBgn0015270
GO:0030466
IEA
PLAZA Integrative Orthologychromatin silencing at silent mating-type cassette YBR060C
GO:0051568
IEA
PLAZA Integrative Orthologyhistone H3-K4 methylation YBR060C
GO:0048609
IEA
PLAZA Integrative Orthologymulticellular organismal reproductive process FBgn0015270
GO:0009889
IEA
PLAZA Integrative Orthologyregulation of biosynthetic process YBR060C
GO:0009888
IEA
PLAZA Integrative Orthologytissue development FBgn0015270
GO:0010629
IEA
PLAZA Integrative Orthologynegative regulation of gene expression YBR060C
GO:0048731
IEA
PLAZA Integrative Orthologysystem development FBgn0015270
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization YBR060C
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis YBR060C
GO:0019438
IEA
PLAZA Integrative Orthologyaromatic compound biosynthetic process YBR060C
GO:0019538
IEA
PLAZA Integrative Orthologyprotein metabolic process YBR060C
GO:0006464
IEA
PLAZA Integrative Orthologycellular protein modification process YBR060C
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development FBgn0015270
GO:0006342
IEA
PLAZA Integrative Orthologychromatin silencing YBR060C
GO:0006348
IEA
PLAZA Integrative Orthologychromatin silencing at telomere YBR060C
GO:0000122
IEA
PLAZA Integrative Orthologynegative regulation of transcription by RNA polymerase II ENSG00000115942
GO:0007306
IEA
PLAZA Integrative Orthologyeggshell chorion assembly FBgn0015270
GO:0032504
IEA
PLAZA Integrative Orthologymulticellular organism reproduction FBgn0015270
GO:0007307
IEA
PLAZA Integrative Orthologyeggshell chorion gene amplification FBgn0015270
GO:0032989
IEA
PLAZA Integrative Orthologycellular component morphogenesis FBgn0015270
GO:0097549
IEA
PLAZA Integrative Orthologychromatin organization involved in negative regulation of transcription YBR060C
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process FBgn0015270
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process FBgn0015270
GO:0044703
IEA
PLAZA Integrative Orthologymulti-organism reproductive process FBgn0015270
GO:0006351
IEA
PLAZA Integrative Orthologytranscription, DNA-templated YBR060C
GO:0044267
IEA
PLAZA Integrative Orthologycellular protein metabolic process YBR060C
GO:0006355
IEA
PLAZA Integrative Orthologyregulation of transcription, DNA-templated YBR060C
GO:0006479
IEA
PLAZA Integrative Orthologyprotein methylation YBR060C
GO:0048869
IEA
PLAZA Integrative Orthologycellular developmental process FBgn0015270
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction FBgn0015270
GO:0006357
IEA
PLAZA Integrative Orthologyregulation of transcription by RNA polymerase II ENSG00000115942
GO:0044271
IEA
PLAZA Integrative Orthologycellular nitrogen compound biosynthetic process YBR060C
GO:0010605
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule metabolic process YBR060C
GO:0018205
IEA
PLAZA Integrative Orthologypeptidyl-lysine modification YBR060C

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Gene Ontologyprotein binding3 4
GO:0003688
ISS
Gene OntologyDNA replication origin binding3 4
GO:0003682
IEA
PLAZA Integrative Orthologychromatin binding YBR060C

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000808
ISS
Gene Ontologyorigin recognition complex3 4
GO:0000808
IEA
InterProorigin recognition complex
GO:0005634
ISM
Gene Ontologynucleus5
GO:0005634
IEA
InterPronucleus
GO:0043233
IEA
PLAZA Integrative Orthologyorganelle lumen SPBC685.09
GO:0043596
IEA
PLAZA Integrative Orthologynuclear replication fork SPBC685.09
GO:0044451
IEA
PLAZA Integrative Orthologynucleoplasm part SPBC685.09
GO:0044454
IEA
PLAZA Integrative Orthologynuclear chromosome part SPBC685.09
GO:0005723
IEA
PLAZA Integrative Orthologyalpha-heterochromatin FBgn0015270
GO:0005856
IEA
PLAZA Integrative Orthologycytoskeleton ENSG00000115942
GO:0000775
IEA
PLAZA Integrative Orthologychromosome, centromeric region FBgn0015270
GO:0000781
IEA
PLAZA Integrative Orthologychromosome, telomeric region ENSG00000115942
GO:0000785
IEA
PLAZA Integrative Orthologychromatin SPBC685.09
GO:0000784
IEA
PLAZA Integrative Orthologynuclear chromosome, telomeric region ENSG00000115942
GO:0000792
IEA
PLAZA Integrative Orthologyheterochromatin ENSG00000115942
GO:0000790
IEA
PLAZA Integrative Orthologynuclear chromatin SPBC685.09
GO:0031261
IEA
PLAZA Integrative OrthologyDNA replication preinitiation complex SPBC685.09
GO:0005654
IEA
PLAZA Integrative Orthologynucleoplasm SPBC685.09
GO:0036387
IEA
PLAZA Integrative Orthologypre-replicative complex SPBC685.09
GO:0044428
IEA
PLAZA Integrative Orthologynuclear part SPBC685.09
GO:0005664
IEA
PLAZA Integrative Orthologynuclear origin of replication recognition complex SPBC685.09
GO:0005657
IEA
PLAZA Integrative Orthologyreplication fork SPBC685.09
GO:0005656
IEA
PLAZA Integrative Orthologynuclear pre-replicative complex SPBC685.09
GO:0070013
IEA
PLAZA Integrative Orthologyintracellular organelle lumen SPBC685.09
GO:0044430
IEA
PLAZA Integrative Orthologycytoskeletal part ENSG00000115942
GO:0000228
IEA
PLAZA Integrative Orthologynuclear chromosome SPBC685.09
GO:0031981
IEA
PLAZA Integrative Orthologynuclear lumen SPBC685.09
GO:0031974
IEA
PLAZA Integrative Orthologymembrane-enclosed lumen SPBC685.09
GO:0098687
IEA
PLAZA Integrative Orthologychromosomal region ENSG00000115942
GO:0010369
IEA
PLAZA Integrative Orthologychromocenter FBgn0015270
GO:0015630
IEA
PLAZA Integrative Orthologymicrotubule cytoskeleton ENSG00000115942
GO:0005701
IEA
PLAZA Integrative Orthologypolytene chromosome chromocenter FBgn0015270
GO:0005700
IEA
PLAZA Integrative Orthologypolytene chromosome FBgn0015270
GO:0005721
IEA
PLAZA Integrative Orthologypericentric heterochromatin FBgn0015270
GO:0032993
IEA
PLAZA Integrative Orthologyprotein-DNA complex SPBC685.09
GO:0005813
IEA
PLAZA Integrative Orthologycentrosome ENSG00000115942
GO:0005815
IEA
PLAZA Integrative Orthologymicrotubule organizing center ENSG00000115942
GO:0016020
IEA
PLAZA Integrative Orthologymembrane ENSG00000115942

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR007220Origin recognition complex, subunit 2

No MapMan annotations defined for this gene.
KeggID Description
K02604ORC2; origin recognition complex subunit 2
No chloroplast target sequence found.