Gene: AT2G21790 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT2G21790
Transcript Identifier
AT2G21790.1
Gene Type
Coding gene
Location
2 : 9293529-9297580 : positive

Family Information

Homologous gene family
HOM02SEM000621
(66 genes in 26 species)
specific family
Orthologous gene family
ORTHO02SEM000913
(52 genes in 26 species)
specific family

Descriptions

Curated Summary
encodes large subunit of ribonucleotide reductase involved in the production of deoxyribonucleoside triphosphates (dNTPs) for DNA replication and repair
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Identifiers

Type Value
uniprotQ9SJ20
aliasR1
aliasDPD2
aliasCRINKLY LEAVES 8
aliasdefective in pollen organelle DNA degradation 2
aliasribonucleotide reductase 1
aliasATRNR1
aliasRNR1
aliasCLS8
aliasRIBONUCLEOTIDE REDUCTASE 1
aliasRIBONUCLEOTIDE REDUCTASE LARGE SUBUNIT 1

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006260
IMP
ISS
Gene OntologyDNA replication1 2 3
GO:0006260
IEA
InterProDNA replication
GO:0055114
IEA
InterProoxidation-reduction process
GO:0009202
IMP
Gene Ontologydeoxyribonucleoside triphosphate biosynthetic process2 3
GO:0046686
IEP
Gene Ontologyresponse to cadmium ion4 5
GO:0050789
IEA
PLAZA Integrative Orthologyregulation of biological process FBgn0011703
GO:0012501
IEA
PLAZA Integrative Orthologyprogrammed cell death FBgn0011703
GO:0043065
IEA
PLAZA Integrative Orthologypositive regulation of apoptotic process FBgn0011703
GO:0006508
IEA
PLAZA Integrative Orthologyproteolysis FBgn0011703
GO:0010604
IEA
PLAZA Integrative Orthologypositive regulation of macromolecule metabolic process FBgn0011703
GO:0006235
IEA
PLAZA Integrative OrthologydTTP biosynthetic process SPAC1F7.05
GO:0042246
IEA
PLAZA Integrative Orthologytissue regeneration FBgn0011703
GO:0048589
IEA
PLAZA Integrative Orthologydevelopmental growth FBgn0011703
GO:0044267
IEA
PLAZA Integrative Orthologycellular protein metabolic process FBgn0011703
GO:0030162
IEA
PLAZA Integrative Orthologyregulation of proteolysis FBgn0011703
GO:0009186
IEA
PLAZA Integrative Orthologydeoxyribonucleoside diphosphate metabolic process SPAC1F7.05
GO:0009221
IEA
PLAZA Integrative Orthologypyrimidine deoxyribonucleotide biosynthetic process SPAC1F7.05
GO:0009189
IEA
PLAZA Integrative Orthologydeoxyribonucleoside diphosphate biosynthetic process SPAC1F7.05
GO:0009185
IEA
PLAZA Integrative Orthologyribonucleoside diphosphate metabolic process SPAC1F7.05
GO:0010950
IEA
PLAZA Integrative Orthologypositive regulation of endopeptidase activity FBgn0011703
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process FBgn0011703
GO:0016310
IEA
PLAZA Integrative Orthologyphosphorylation SPAC1F7.05
GO:0031099
IEA
PLAZA Integrative Orthologyregeneration FBgn0011703
GO:0010952
IEA
PLAZA Integrative Orthologypositive regulation of peptidase activity FBgn0011703
GO:0051345
IEA
PLAZA Integrative Orthologypositive regulation of hydrolase activity FBgn0011703
GO:0009218
IEA
PLAZA Integrative Orthologypyrimidine ribonucleotide metabolic process SPAC1F7.05
GO:0009219
IEA
PLAZA Integrative Orthologypyrimidine deoxyribonucleotide metabolic process SPAC1F7.05
GO:0045862
IEA
PLAZA Integrative Orthologypositive regulation of proteolysis FBgn0011703
GO:0009212
IEA
PLAZA Integrative Orthologypyrimidine deoxyribonucleoside triphosphate biosynthetic process SPAC1F7.05
GO:1901566
IEA
PLAZA Integrative Orthologyorganonitrogen compound biosynthetic process SPAC1F7.05
GO:0006221
IEA
PLAZA Integrative Orthologypyrimidine nucleotide biosynthetic process SPAC1F7.05
GO:0006220
IEA
PLAZA Integrative Orthologypyrimidine nucleotide metabolic process SPAC1F7.05
GO:1901564
IEA
PLAZA Integrative Orthologyorganonitrogen compound metabolic process SPAC1F7.05
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development FBgn0011703
GO:0009611
IEA
PLAZA Integrative Orthologyresponse to wounding FBgn0011703
GO:0009211
IEA
PLAZA Integrative Orthologypyrimidine deoxyribonucleoside triphosphate metabolic process SPAC1F7.05
GO:0019538
IEA
PLAZA Integrative Orthologyprotein metabolic process FBgn0011703
GO:0052547
IEA
PLAZA Integrative Orthologyregulation of peptidase activity FBgn0011703
GO:0051336
IEA
PLAZA Integrative Orthologyregulation of hydrolase activity FBgn0011703
GO:0052548
IEA
PLAZA Integrative Orthologyregulation of endopeptidase activity FBgn0011703
GO:0043281
IEA
PLAZA Integrative Orthologyregulation of cysteine-type endopeptidase activity involved in apoptotic process FBgn0011703
GO:0044093
IEA
PLAZA Integrative Orthologypositive regulation of molecular function FBgn0011703
GO:0043280
IEA
PLAZA Integrative Orthologypositive regulation of cysteine-type endopeptidase activity involved in apoptotic process FBgn0011703
GO:0009888
IEA
PLAZA Integrative Orthologytissue development FBgn0011703
GO:0046704
IEA
PLAZA Integrative OrthologyCDP metabolic process SPAC1F7.05
GO:0042981
IEA
PLAZA Integrative Orthologyregulation of apoptotic process FBgn0011703
GO:0006919
IEA
PLAZA Integrative Orthologyactivation of cysteine-type endopeptidase activity involved in apoptotic process FBgn0011703
GO:0006915
IEA
PLAZA Integrative Orthologyapoptotic process FBgn0011703
GO:0046385
IEA
PLAZA Integrative Orthologydeoxyribose phosphate biosynthetic process SPAC1F7.05
GO:0042060
IEA
PLAZA Integrative Orthologywound healing FBgn0011703
GO:0009117
IEA
PLAZA Integrative Orthologynucleotide metabolic process SPAC1F7.05
GO:0009119
IEA
PLAZA Integrative Orthologyribonucleoside metabolic process SPAC1F7.05
GO:0051171
IEA
PLAZA Integrative Orthologyregulation of nitrogen compound metabolic process FBgn0011703
GO:0051173
IEA
PLAZA Integrative Orthologypositive regulation of nitrogen compound metabolic process FBgn0011703
GO:0009116
IEA
PLAZA Integrative Orthologynucleoside metabolic process SPAC1F7.05
GO:0009197
IEA
PLAZA Integrative Orthologypyrimidine deoxyribonucleoside diphosphate biosynthetic process SPAC1F7.05
GO:0006240
IEA
PLAZA Integrative OrthologydCDP biosynthetic process SPAC1F7.05
GO:0009193
IEA
PLAZA Integrative Orthologypyrimidine ribonucleoside diphosphate metabolic process SPAC1F7.05
GO:0046939
IEA
PLAZA Integrative Orthologynucleotide phosphorylation SPAC1F7.05
GO:0009196
IEA
PLAZA Integrative Orthologypyrimidine deoxyribonucleoside diphosphate metabolic process SPAC1F7.05
GO:0031323
IEA
PLAZA Integrative Orthologyregulation of cellular metabolic process FBgn0011703
GO:0080090
IEA
PLAZA Integrative Orthologyregulation of primary metabolic process FBgn0011703
GO:0031325
IEA
PLAZA Integrative Orthologypositive regulation of cellular metabolic process FBgn0011703
GO:0019693
IEA
PLAZA Integrative Orthologyribose phosphate metabolic process SPAC1F7.05
GO:0019692
IEA
PLAZA Integrative Orthologydeoxyribose phosphate metabolic process SPAC1F7.05
GO:0046131
IEA
PLAZA Integrative Orthologypyrimidine ribonucleoside metabolic process SPAC1F7.05
GO:0006950
IEA
PLAZA Integrative Orthologyresponse to stress FBgn0011703
GO:1901657
IEA
PLAZA Integrative Orthologyglycosyl compound metabolic process SPAC1F7.05
GO:1901137
IEA
PLAZA Integrative Orthologycarbohydrate derivative biosynthetic process SPAC1F7.05
GO:0009147
IEA
PLAZA Integrative Orthologypyrimidine nucleoside triphosphate metabolic process SPAC1F7.05
GO:0009148
IEA
PLAZA Integrative Orthologypyrimidine nucleoside triphosphate biosynthetic process SPAC1F7.05
GO:1901135
IEA
PLAZA Integrative Orthologycarbohydrate derivative metabolic process SPAC1F7.05
GO:0009263
IEA
PLAZA Integrative Orthologydeoxyribonucleotide biosynthetic process SPAC1F7.05
GO:0009265
IEA
PLAZA Integrative Orthology2'-deoxyribonucleotide biosynthetic process SPAC1F7.05
GO:0060255
IEA
PLAZA Integrative Orthologyregulation of macromolecule metabolic process FBgn0011703
GO:0009262
IEA
PLAZA Integrative Orthologydeoxyribonucleotide metabolic process SPAC1F7.05
GO:0072527
IEA
PLAZA Integrative Orthologypyrimidine-containing compound metabolic process SPAC1F7.05
GO:0072528
IEA
PLAZA Integrative Orthologypyrimidine-containing compound biosynthetic process SPAC1F7.05
GO:0032268
IEA
PLAZA Integrative Orthologyregulation of cellular protein metabolic process FBgn0011703
GO:0019222
IEA
PLAZA Integrative Orthologyregulation of metabolic process FBgn0011703
GO:0009139
IEA
PLAZA Integrative Orthologypyrimidine nucleoside diphosphate biosynthetic process SPAC1F7.05
GO:0009259
IEA
PLAZA Integrative Orthologyribonucleotide metabolic process SPAC1F7.05
GO:0009138
IEA
PLAZA Integrative Orthologypyrimidine nucleoside diphosphate metabolic process SPAC1F7.05
GO:0009132
IEA
PLAZA Integrative Orthologynucleoside diphosphate metabolic process SPAC1F7.05
GO:0009133
IEA
PLAZA Integrative Orthologynucleoside diphosphate biosynthetic process SPAC1F7.05
GO:0009893
IEA
PLAZA Integrative Orthologypositive regulation of metabolic process FBgn0011703
GO:0032270
IEA
PLAZA Integrative Orthologypositive regulation of cellular protein metabolic process FBgn0011703
GO:2001056
IEA
PLAZA Integrative Orthologypositive regulation of cysteine-type endopeptidase activity FBgn0011703
GO:0010942
IEA
PLAZA Integrative Orthologypositive regulation of cell death FBgn0011703
GO:0010941
IEA
PLAZA Integrative Orthologyregulation of cell death FBgn0011703
GO:0043085
IEA
PLAZA Integrative Orthologypositive regulation of catalytic activity FBgn0011703
GO:0046075
IEA
PLAZA Integrative OrthologydTTP metabolic process SPAC1F7.05
GO:0040007
IEA
PLAZA Integrative Orthologygrowth FBgn0011703
GO:0065009
IEA
PLAZA Integrative Orthologyregulation of molecular function FBgn0011703
GO:0006213
IEA
PLAZA Integrative Orthologypyrimidine nucleoside metabolic process SPAC1F7.05
GO:0009165
IEA
PLAZA Integrative Orthologynucleotide biosynthetic process SPAC1F7.05
GO:0065007
IEA
PLAZA Integrative Orthologybiological regulation FBgn0011703
GO:2000116
IEA
PLAZA Integrative Orthologyregulation of cysteine-type endopeptidase activity FBgn0011703
GO:0050790
IEA
PLAZA Integrative Orthologyregulation of catalytic activity FBgn0011703
GO:0015949
IEA
PLAZA Integrative Orthologynucleobase-containing small molecule interconversion ENSG00000167325
GO:0048522
IEA
PLAZA Integrative Orthologypositive regulation of cellular process FBgn0011703
GO:0050794
IEA
PLAZA Integrative Orthologyregulation of cellular process FBgn0011703
GO:0008219
IEA
PLAZA Integrative Orthologycell death FBgn0011703
GO:0046062
IEA
PLAZA Integrative OrthologydCDP metabolic process SPAC1F7.05
GO:0051247
IEA
PLAZA Integrative Orthologypositive regulation of protein metabolic process FBgn0011703
GO:0051246
IEA
PLAZA Integrative Orthologyregulation of protein metabolic process FBgn0011703
GO:0048518
IEA
PLAZA Integrative Orthologypositive regulation of biological process FBgn0011703
GO:0006165
IEA
PLAZA Integrative Orthologynucleoside diphosphate phosphorylation SPAC1F7.05
GO:0043067
IEA
PLAZA Integrative Orthologyregulation of programmed cell death FBgn0011703
GO:0043068
IEA
PLAZA Integrative Orthologypositive regulation of programmed cell death FBgn0011703
GO:0009394
IEA
PLAZA Integrative Orthology2'-deoxyribonucleotide metabolic process SPAC1F7.05

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004748
ISS
Gene Ontologyribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor1
GO:0004748
IEA
InterProribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005524
IEA
InterProATP binding
GO:0016301
IEA
PLAZA Integrative Orthologykinase activity SPAC1F7.05
GO:0042802
IEA
PLAZA Integrative Orthologyidentical protein binding ENSG00000167325
GO:0051063
IEA
PLAZA Integrative OrthologyCDP reductase activity SPAC1F7.05
GO:0019205
IEA
PLAZA Integrative Orthologynucleobase-containing compound kinase activity SPAC1F7.05
GO:0016740
IEA
PLAZA Integrative Orthologytransferase activity SPAC1F7.05
GO:0005515
IEA
PLAZA Integrative Orthologyprotein binding SPAC1F7.05
GO:0004550
IEA
PLAZA Integrative Orthologynucleoside diphosphate kinase activity SPAC1F7.05
GO:0016776
IEA
PLAZA Integrative Orthologyphosphotransferase activity, phosphate group as acceptor SPAC1F7.05
GO:0016772
IEA
PLAZA Integrative Orthologytransferase activity, transferring phosphorus-containing groups SPAC1F7.05

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005971
ISS
Gene Ontologyribonucleoside-diphosphate reductase complex1
GO:0005737
ISM
Gene Ontologycytoplasm6
GO:0044421
IEA
PLAZA Integrative Orthologyextracellular region part ENSG00000167325
GO:1903561
IEA
PLAZA Integrative Orthologyextracellular vesicle ENSG00000167325
GO:0005739
IEA
PLAZA Integrative Orthologymitochondrion YIL066C
GO:0005615
IEA
PLAZA Integrative Orthologyextracellular space ENSG00000167325
GO:0070062
IEA
PLAZA Integrative Orthologyextracellular exosome ENSG00000167325
GO:0005576
IEA
PLAZA Integrative Orthologyextracellular region ENSG00000167325
GO:0031982
IEA
PLAZA Integrative Orthologyvesicle ENSG00000167325
GO:0005634
IEA
PLAZA Integrative Orthologynucleus YER070W
GO:0043230
IEA
PLAZA Integrative Orthologyextracellular organelle ENSG00000167325
GO:0043231
IEA
PLAZA Integrative Orthologyintracellular membrane-bounded organelle YER070W
GO:0043227
IEA
PLAZA Integrative Orthologymembrane-bounded organelle YER070W
GO:0043226
IEA
PLAZA Integrative Orthologyorganelle YER070W
GO:0043229
IEA
PLAZA Integrative Orthologyintracellular organelle YER070W

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000788Ribonucleotide reductase large subunit, C-terminal
IPR005144ATP-cone domain
IPR013509Ribonucleotide reductase large subunit, N-terminal
IPR008926Ribonucleotide reductase R1 subunit, N-terminal
IPR013346Ribonucleotide reductase, class I , alpha subunit

No MapMan annotations defined for this gene.
KeggID Description
K10807RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
No chloroplast target sequence found.