Gene: AT2G01120 (Arabidopsis thaliana)

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Gene Identifier
AT2G01120
Transcript Identifier
AT2G01120.2
Gene Type
Coding gene
Location
2 : 85444-88027 : positive

Family Information

Homologous gene family
HOM02SEM006756
(13 genes in 12 species)
specific family

Descriptions

Curated Summary
Origin Recognition Complex subunit 4. Involved in the initiation of DNA replication. Regulated transcriptionally during cell cycle, peaking at G1/S-phase. Target of E2F/DF family of transcription factors. Interacts with all ORC subunits except ORC1b.
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Identifiers

Type Value
aliasorigin recognition complex subunit 4
aliasORC4
aliasORIGIN RECOGNITION COMPLEX SUBUNIT 4
aliasATORC4

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006260
ISS
Gene OntologyDNA replication1 2
GO:0006260
IEA
InterProDNA replication
GO:0050789
IEA
PLAZA Integrative Orthologyregulation of biological process YPR162C
GO:0071103
IEA
PLAZA Integrative OrthologyDNA conformation change SPBP23A10.13
GO:0010605
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule metabolic process YPR162C
GO:0044271
IEA
PLAZA Integrative Orthologycellular nitrogen compound biosynthetic process YPR162C
GO:0007049
IEA
PLAZA Integrative Orthologycell cycle SPBP23A10.13
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization SPBP23A10.13
GO:0044786
IEA
PLAZA Integrative Orthologycell cycle DNA replication SPBP23A10.13
GO:0006355
IEA
PLAZA Integrative Orthologyregulation of transcription, DNA-templated YPR162C
GO:0006351
IEA
PLAZA Integrative Orthologytranscription, DNA-templated YPR162C
GO:0036388
IEA
PLAZA Integrative Orthologypre-replicative complex assembly YPR162C
GO:0097549
IEA
PLAZA Integrative Orthologychromatin organization involved in negative regulation of transcription YPR162C
GO:0010558
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule biosynthetic process YPR162C
GO:0034401
IEA
PLAZA Integrative Orthologychromatin organization involved in regulation of transcription YPR162C
GO:0010556
IEA
PLAZA Integrative Orthologyregulation of macromolecule biosynthetic process YPR162C
GO:0000082
IEA
PLAZA Integrative OrthologyG1/S transition of mitotic cell cycle ENSG00000115947
GO:0051101
IEA
PLAZA Integrative Orthologyregulation of DNA binding SPBP23A10.13
GO:1903507
IEA
PLAZA Integrative Orthologynegative regulation of nucleic acid-templated transcription YPR162C
GO:1903506
IEA
PLAZA Integrative Orthologyregulation of nucleic acid-templated transcription YPR162C
GO:0006342
IEA
PLAZA Integrative Orthologychromatin silencing YPR162C
GO:0044772
IEA
PLAZA Integrative Orthologymitotic cell cycle phase transition ENSG00000115947
GO:0019438
IEA
PLAZA Integrative Orthologyaromatic compound biosynthetic process YPR162C
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis SPBP23A10.13
GO:0034654
IEA
PLAZA Integrative Orthologynucleobase-containing compound biosynthetic process YPR162C
GO:0010467
IEA
PLAZA Integrative Orthologygene expression YPR162C
GO:0010468
IEA
PLAZA Integrative Orthologyregulation of gene expression YPR162C
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization SPBP23A10.13
GO:0044770
IEA
PLAZA Integrative Orthologycell cycle phase transition ENSG00000115947
GO:0010629
IEA
PLAZA Integrative Orthologynegative regulation of gene expression YPR162C
GO:0044093
IEA
PLAZA Integrative Orthologypositive regulation of molecular function SPBP23A10.13
GO:0009889
IEA
PLAZA Integrative Orthologyregulation of biosynthetic process YPR162C
GO:2001141
IEA
PLAZA Integrative Orthologyregulation of RNA biosynthetic process YPR162C
GO:0030466
IEA
PLAZA Integrative Orthologychromatin silencing at silent mating-type cassette YPR162C
GO:0044085
IEA
PLAZA Integrative Orthologycellular component biogenesis YPR162C
GO:0051171
IEA
PLAZA Integrative Orthologyregulation of nitrogen compound metabolic process YPR162C
GO:0043388
IEA
PLAZA Integrative Orthologypositive regulation of DNA binding SPBP23A10.13
GO:0051172
IEA
PLAZA Integrative Orthologynegative regulation of nitrogen compound metabolic process YPR162C
GO:0022607
IEA
PLAZA Integrative Orthologycellular component assembly YPR162C
GO:1902595
IEA
PLAZA Integrative Orthologyregulation of DNA replication origin binding SPBP23A10.13
GO:1902597
IEA
PLAZA Integrative Orthologypositive regulation of DNA replication origin binding SPBP23A10.13
GO:1903047
IEA
PLAZA Integrative Orthologymitotic cell cycle process SPBP23A10.13
GO:0031324
IEA
PLAZA Integrative Orthologynegative regulation of cellular metabolic process YPR162C
GO:0031323
IEA
PLAZA Integrative Orthologyregulation of cellular metabolic process YPR162C
GO:0080090
IEA
PLAZA Integrative Orthologyregulation of primary metabolic process YPR162C
GO:0031326
IEA
PLAZA Integrative Orthologyregulation of cellular biosynthetic process YPR162C
GO:0071824
IEA
PLAZA Integrative Orthologyprotein-DNA complex subunit organization YPR162C
GO:0032774
IEA
PLAZA Integrative OrthologyRNA biosynthetic process YPR162C
GO:0051276
IEA
PLAZA Integrative Orthologychromosome organization SPBP23A10.13
GO:0031327
IEA
PLAZA Integrative Orthologynegative regulation of cellular biosynthetic process YPR162C
GO:0040029
IEA
PLAZA Integrative Orthologyregulation of gene expression, epigenetic YPR162C
GO:0060255
IEA
PLAZA Integrative Orthologyregulation of macromolecule metabolic process YPR162C
GO:0043933
IEA
PLAZA Integrative Orthologyprotein-containing complex subunit organization YPR162C
GO:0006270
IEA
PLAZA Integrative OrthologyDNA replication initiation SPBP23A10.13
GO:0016458
IEA
PLAZA Integrative Orthologygene silencing YPR162C
GO:1902292
IEA
PLAZA Integrative Orthologycell cycle DNA replication initiation SPBP23A10.13
GO:0019222
IEA
PLAZA Integrative Orthologyregulation of metabolic process YPR162C
GO:0018130
IEA
PLAZA Integrative Orthologyheterocycle biosynthetic process YPR162C
GO:0016070
IEA
PLAZA Integrative OrthologyRNA metabolic process YPR162C
GO:1902969
IEA
PLAZA Integrative Orthologymitotic DNA replication SPBP23A10.13
GO:0000278
IEA
PLAZA Integrative Orthologymitotic cell cycle SPBP23A10.13
GO:0006265
IEA
PLAZA Integrative OrthologyDNA topological change SPBP23A10.13
GO:0006267
IEA
PLAZA Integrative Orthologypre-replicative complex assembly involved in nuclear cell cycle DNA replication YPR162C
GO:1902975
IEA
PLAZA Integrative Orthologymitotic DNA replication initiation SPBP23A10.13
GO:0009890
IEA
PLAZA Integrative Orthologynegative regulation of biosynthetic process YPR162C
GO:0006261
IEA
PLAZA Integrative OrthologyDNA-dependent DNA replication SPBP23A10.13
GO:1901362
IEA
PLAZA Integrative Orthologyorganic cyclic compound biosynthetic process YPR162C
GO:0009892
IEA
PLAZA Integrative Orthologynegative regulation of metabolic process YPR162C
GO:1902299
IEA
PLAZA Integrative Orthologypre-replicative complex assembly involved in cell cycle DNA replication YPR162C
GO:0019219
IEA
PLAZA Integrative Orthologyregulation of nucleobase-containing compound metabolic process YPR162C
GO:0097659
IEA
PLAZA Integrative Orthologynucleic acid-templated transcription YPR162C
GO:0051252
IEA
PLAZA Integrative Orthologyregulation of RNA metabolic process YPR162C
GO:0051098
IEA
PLAZA Integrative Orthologyregulation of binding SPBP23A10.13
GO:0051253
IEA
PLAZA Integrative Orthologynegative regulation of RNA metabolic process YPR162C
GO:0051099
IEA
PLAZA Integrative Orthologypositive regulation of binding SPBP23A10.13
GO:0065009
IEA
PLAZA Integrative Orthologyregulation of molecular function SPBP23A10.13
GO:0045934
IEA
PLAZA Integrative Orthologynegative regulation of nucleobase-containing compound metabolic process YPR162C
GO:0044843
IEA
PLAZA Integrative Orthologycell cycle G1/S phase transition ENSG00000115947
GO:0048523
IEA
PLAZA Integrative Orthologynegative regulation of cellular process YPR162C
GO:0065004
IEA
PLAZA Integrative Orthologyprotein-DNA complex assembly YPR162C
GO:0065003
IEA
PLAZA Integrative Orthologyprotein-containing complex assembly YPR162C
GO:0045814
IEA
PLAZA Integrative Orthologynegative regulation of gene expression, epigenetic YPR162C
GO:0065007
IEA
PLAZA Integrative Orthologybiological regulation SPBP23A10.13
GO:2000112
IEA
PLAZA Integrative Orthologyregulation of cellular macromolecule biosynthetic process YPR162C
GO:2000113
IEA
PLAZA Integrative Orthologynegative regulation of cellular macromolecule biosynthetic process YPR162C
GO:0034622
IEA
PLAZA Integrative Orthologycellular protein-containing complex assembly YPR162C
GO:0045892
IEA
PLAZA Integrative Orthologynegative regulation of transcription, DNA-templated YPR162C
GO:0050794
IEA
PLAZA Integrative Orthologyregulation of cellular process YPR162C
GO:1902679
IEA
PLAZA Integrative Orthologynegative regulation of RNA biosynthetic process YPR162C
GO:0048519
IEA
PLAZA Integrative Orthologynegative regulation of biological process YPR162C
GO:0006325
IEA
PLAZA Integrative Orthologychromatin organization YPR162C
GO:1902315
IEA
PLAZA Integrative Orthologynuclear cell cycle DNA replication initiation SPBP23A10.13
GO:0022402
IEA
PLAZA Integrative Orthologycell cycle process SPBP23A10.13
GO:0033260
IEA
PLAZA Integrative Orthologynuclear DNA replication SPBP23A10.13

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
IEA
InterProDNA binding
GO:0005524
IEA
InterProATP binding
GO:0005515
IPI
Gene Ontologyprotein binding1 2
GO:0043565
IEA
PLAZA Integrative Orthologysequence-specific DNA binding SPBP23A10.13
GO:1990837
IEA
PLAZA Integrative Orthologysequence-specific double-stranded DNA binding SPBP23A10.13
GO:0003688
IEA
PLAZA Integrative OrthologyDNA replication origin binding SPBP23A10.13
GO:0003690
IEA
PLAZA Integrative Orthologydouble-stranded DNA binding SPBP23A10.13

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000808
ISS
Gene Ontologyorigin recognition complex1 2
GO:0000808
IEA
InterProorigin recognition complex
GO:0005634
ISM
Gene Ontologynucleus3
GO:0005634
IEA
InterPronucleus
GO:0070013
IEA
PLAZA Integrative Orthologyintracellular organelle lumen SPBP23A10.13
GO:0005656
IEA
PLAZA Integrative Orthologynuclear pre-replicative complex SPBP23A10.13
GO:0005657
IEA
PLAZA Integrative Orthologyreplication fork SPBP23A10.13
GO:0005664
IEA
PLAZA Integrative Orthologynuclear origin of replication recognition complex SPBP23A10.13
GO:0044428
IEA
PLAZA Integrative Orthologynuclear part SPBP23A10.13
GO:0036387
IEA
PLAZA Integrative Orthologypre-replicative complex SPBP23A10.13
GO:0005654
IEA
PLAZA Integrative Orthologynucleoplasm SPBP23A10.13
GO:0031261
IEA
PLAZA Integrative OrthologyDNA replication preinitiation complex SPBP23A10.13
GO:0032993
IEA
PLAZA Integrative Orthologyprotein-DNA complex SPBP23A10.13
GO:0000790
IEA
PLAZA Integrative Orthologynuclear chromatin SPBP23A10.13
GO:0000784
IEA
PLAZA Integrative Orthologynuclear chromosome, telomeric region ENSG00000115947
GO:0000785
IEA
PLAZA Integrative Orthologychromatin SPBP23A10.13
GO:0005829
IEA
PLAZA Integrative Orthologycytosol ENSG00000115947
GO:0000781
IEA
PLAZA Integrative Orthologychromosome, telomeric region ENSG00000115947
GO:0098687
IEA
PLAZA Integrative Orthologychromosomal region ENSG00000115947
GO:0005737
IEA
PLAZA Integrative Orthologycytoplasm ENSG00000115947
GO:0031974
IEA
PLAZA Integrative Orthologymembrane-enclosed lumen SPBP23A10.13
GO:0005730
IEA
PLAZA Integrative Orthologynucleolus ENSG00000115947
GO:0044454
IEA
PLAZA Integrative Orthologynuclear chromosome part SPBP23A10.13
GO:0031981
IEA
PLAZA Integrative Orthologynuclear lumen SPBP23A10.13
GO:0044451
IEA
PLAZA Integrative Orthologynucleoplasm part SPBP23A10.13
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part ENSG00000115947
GO:0000228
IEA
PLAZA Integrative Orthologynuclear chromosome SPBP23A10.13
GO:0043596
IEA
PLAZA Integrative Orthologynuclear replication fork SPBP23A10.13
GO:0043233
IEA
PLAZA Integrative Orthologyorganelle lumen SPBP23A10.13

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR027417P-loop containing nucleoside triphosphate hydrolase
IPR016527Origin recognition complex subunit 4
IPR032705Origin recognition complex subunit 4, C-terminal
IPR003959ATPase, AAA-type, core

No MapMan annotations defined for this gene.
KeggID Description
K02606ORC4; origin recognition complex subunit 4
No chloroplast target sequence found.