Gene: AT1G78870 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G78870
Transcript Identifier
AT1G78870.1
Gene Type
Coding gene
Location
1 : 29650589-29652203 : positive

Family Information

Homologous gene family
HOM02SEM000029
(475 genes in 26 species)
specific family
Orthologous gene family
ORTHO02SEM000122
(172 genes in 26 species)
specific family
Duplication type
Block duplicate

Descriptions

Description
ubiquitin-conjugating enzyme 35
Curated Summary
UBC35/UBC13A encodes a protein that may play a role in DNA damage responses and error-free post-replicative DNA repair by participating in lysine-63-based polyubiquitination reactions. UBC35/UBC13A can form diubiquitin and triubiquitin chains in combination with MMZ1,2,3,4/(UEV1A,B,C,D) in vitro. It can also functionally complement an mms2 ubc13 mutation in budding yeast by increasing the double mutant's viability in the presence of the DNA damaging agent MMS, when it is co-expressed with MMZ / UEV1 genes. A wild type phenotype is restored with MMZ3/UEV1C and MMZ4/UEV1D, but only partial complementation is achieved with MMZ1/UEV1A or MMZ2/UEV1B.
Show more...

Identifiers

Type Value
uniprotQ94A97
aliasUBC35
aliasUBC13A
aliasUBIQUITIN CONJUGATING ENZYME 13A

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0010053
IGI
Gene Ontologyroot epidermal cell differentiation1 2
GO:0010039
IMP
Gene Ontologyresponse to iron ion1 2
GO:0006301
IGI
Gene Ontologypostreplication repair3 4
GO:0046686
IEP
Gene Ontologyresponse to cadmium ion5 6
GO:0006511
IDA
Gene Ontologyubiquitin-dependent protein catabolic process7 8
GO:0031401
IEA
PLAZA Integrative Orthologypositive regulation of protein modification process FBgn0000173
GO:0051239
IEA
PLAZA Integrative Orthologyregulation of multicellular organismal process FBgn0000173
GO:0070534
IEA
PLAZA Integrative Orthologyprotein K63-linked ubiquitination SPAC11E3.04c
GO:0046330
IEA
PLAZA Integrative Orthologypositive regulation of JNK cascade FBgn0000173
GO:0010604
IEA
PLAZA Integrative Orthologypositive regulation of macromolecule metabolic process FBgn0000173
GO:0009617
IEA
PLAZA Integrative Orthologyresponse to bacterium FBgn0000173
GO:0046328
IEA
PLAZA Integrative Orthologyregulation of JNK cascade FBgn0000173
GO:0031098
IEA
PLAZA Integrative Orthologystress-activated protein kinase signaling cascade FBgn0000173
GO:0070304
IEA
PLAZA Integrative Orthologypositive regulation of stress-activated protein kinase signaling cascade FBgn0000173
GO:0033036
IEA
PLAZA Integrative Orthologymacromolecule localization SPAC11E3.04c
GO:0070302
IEA
PLAZA Integrative Orthologyregulation of stress-activated protein kinase signaling cascade FBgn0000173
GO:0032989
IEA
PLAZA Integrative Orthologycellular component morphogenesis FBgn0000173
GO:0009605
IEA
PLAZA Integrative Orthologyresponse to external stimulus FBgn0000173
GO:0009607
IEA
PLAZA Integrative Orthologyresponse to biotic stimulus FBgn0000173
GO:0048858
IEA
PLAZA Integrative Orthologycell projection morphogenesis FBgn0000173
GO:0006468
IEA
PLAZA Integrative Orthologyprotein phosphorylation FBgn0000173
GO:0006464
IEA
PLAZA Integrative Orthologycellular protein modification process SPAC11E3.04c
GO:0032990
IEA
PLAZA Integrative Orthologycell part morphogenesis FBgn0000173
GO:0032874
IEA
PLAZA Integrative Orthologypositive regulation of stress-activated MAPK cascade FBgn0000173
GO:0104004
IEA
PLAZA Integrative Orthologycellular response to environmental stimulus SPAC11E3.04c
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis YDR092W
GO:0032872
IEA
PLAZA Integrative Orthologyregulation of stress-activated MAPK cascade FBgn0000173
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization YDR092W
GO:0032879
IEA
PLAZA Integrative Orthologyregulation of localization WBGene00006708
GO:1902914
IEA
PLAZA Integrative Orthologyregulation of protein polyubiquitination FBgn0000173
GO:1902916
IEA
PLAZA Integrative Orthologypositive regulation of protein polyubiquitination FBgn0000173
GO:0098542
IEA
PLAZA Integrative Orthologydefense response to other organism FBgn0000173
GO:0007346
IEA
PLAZA Integrative Orthologyregulation of mitotic cell cycle FBgn0000173
GO:0042742
IEA
PLAZA Integrative Orthologydefense response to bacterium FBgn0000173
GO:0050808
IEA
PLAZA Integrative Orthologysynapse organization FBgn0000173
GO:0032880
IEA
PLAZA Integrative Orthologyregulation of protein localization WBGene00006708
GO:0070647
IEA
PLAZA Integrative Orthologyprotein modification by small protein conjugation or removal SPAC11E3.04c
GO:0009628
IEA
PLAZA Integrative Orthologyresponse to abiotic stimulus SPAC11E3.04c
GO:0045448
IEA
PLAZA Integrative Orthologymitotic cell cycle, embryonic FBgn0000173
GO:0023014
IEA
PLAZA Integrative Orthologysignal transduction by protein phosphorylation FBgn0000173
GO:0022607
IEA
PLAZA Integrative Orthologycellular component assembly YDR092W
GO:1903320
IEA
PLAZA Integrative Orthologyregulation of protein modification by small protein conjugation or removal FBgn0000173
GO:0120039
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection morphogenesis FBgn0000173
GO:1903322
IEA
PLAZA Integrative Orthologypositive regulation of protein modification by small protein conjugation or removal FBgn0000173
GO:0120036
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection organization FBgn0000173
GO:0036211
IEA
PLAZA Integrative Orthologyprotein modification process SPAC11E3.04c
GO:0034394
IEA
PLAZA Integrative Orthologyprotein localization to cell surface WBGene00006708
GO:1903827
IEA
PLAZA Integrative Orthologyregulation of cellular protein localization WBGene00006708
GO:0042325
IEA
PLAZA Integrative Orthologyregulation of phosphorylation FBgn0000173
GO:0006796
IEA
PLAZA Integrative Orthologyphosphate-containing compound metabolic process FBgn0000173
GO:0043412
IEA
PLAZA Integrative Orthologymacromolecule modification SPAC11E3.04c
GO:0043410
IEA
PLAZA Integrative Orthologypositive regulation of MAPK cascade FBgn0000173
GO:0006793
IEA
PLAZA Integrative Orthologyphosphorus metabolic process FBgn0000173
GO:0048666
IEA
PLAZA Integrative Orthologyneuron development FBgn0000173
GO:0048667
IEA
PLAZA Integrative Orthologycell morphogenesis involved in neuron differentiation FBgn0000173
GO:0000209
IEA
PLAZA Integrative Orthologyprotein polyubiquitination SPAC11E3.04c
GO:0031175
IEA
PLAZA Integrative Orthologyneuron projection development FBgn0000173
GO:0019725
IEA
PLAZA Integrative Orthologycellular homeostasis YDR092W
GO:0042327
IEA
PLAZA Integrative Orthologypositive regulation of phosphorylation FBgn0000173
GO:0051704
IEA
PLAZA Integrative Orthologymulti-organism process FBgn0000173
GO:0032268
IEA
PLAZA Integrative Orthologyregulation of cellular protein metabolic process FBgn0000173
GO:0007629
IEA
PLAZA Integrative Orthologyflight behavior FBgn0000173
GO:0007626
IEA
PLAZA Integrative Orthologylocomotory behavior FBgn0000173
GO:0007625
IEA
PLAZA Integrative Orthologygrooming behavior FBgn0000173
GO:0040019
IEA
PLAZA Integrative Orthologypositive regulation of embryonic development FBgn0000173
GO:0007630
IEA
PLAZA Integrative Orthologyjump response FBgn0000173
GO:0051707
IEA
PLAZA Integrative Orthologyresponse to other organism FBgn0000173
GO:0043408
IEA
PLAZA Integrative Orthologyregulation of MAPK cascade FBgn0000173
GO:0032270
IEA
PLAZA Integrative Orthologypositive regulation of cellular protein metabolic process FBgn0000173
GO:0030534
IEA
PLAZA Integrative Orthologyadult behavior FBgn0000173
GO:0010942
IEA
PLAZA Integrative Orthologypositive regulation of cell death FBgn0000173
GO:0033365
IEA
PLAZA Integrative Orthologyprotein localization to organelle SPAC11E3.04c
GO:0010941
IEA
PLAZA Integrative Orthologyregulation of cell death FBgn0000173
GO:0007416
IEA
PLAZA Integrative Orthologysynapse assembly FBgn0000173
GO:0051258
IEA
PLAZA Integrative Orthologyprotein polymerization YDR092W
GO:0045931
IEA
PLAZA Integrative Orthologypositive regulation of mitotic cell cycle FBgn0000173
GO:0040007
IEA
PLAZA Integrative Orthologygrowth FBgn0000173
GO:0009966
IEA
PLAZA Integrative Orthologyregulation of signal transduction FBgn0000173
GO:0009967
IEA
PLAZA Integrative Orthologypositive regulation of signal transduction FBgn0000173
GO:0021700
IEA
PLAZA Integrative Orthologydevelopmental maturation FBgn0000173
GO:0000902
IEA
PLAZA Integrative Orthologycell morphogenesis FBgn0000173
GO:0060074
IEA
PLAZA Integrative Orthologysynapse maturation FBgn0000173
GO:0000904
IEA
PLAZA Integrative Orthologycell morphogenesis involved in differentiation FBgn0000173
GO:0045937
IEA
PLAZA Integrative Orthologypositive regulation of phosphate metabolic process FBgn0000173
GO:0035556
IEA
PLAZA Integrative Orthologyintracellular signal transduction FBgn0000173
GO:0051240
IEA
PLAZA Integrative Orthologypositive regulation of multicellular organismal process FBgn0000173
GO:0007409
IEA
PLAZA Integrative Orthologyaxonogenesis FBgn0000173
GO:0048522
IEA
PLAZA Integrative Orthologypositive regulation of cellular process FBgn0000173
GO:0051124
IEA
PLAZA Integrative Orthologysynaptic growth at neuromuscular junction FBgn0000173
GO:0051247
IEA
PLAZA Integrative Orthologypositive regulation of protein metabolic process FBgn0000173
GO:0051246
IEA
PLAZA Integrative Orthologyregulation of protein metabolic process FBgn0000173
GO:0007528
IEA
PLAZA Integrative Orthologyneuromuscular junction development FBgn0000173
GO:0007412
IEA
PLAZA Integrative Orthologyaxon target recognition FBgn0000173
GO:0048518
IEA
PLAZA Integrative Orthologypositive regulation of biological process FBgn0000173
GO:0022008
IEA
PLAZA Integrative Orthologyneurogenesis FBgn0000173
GO:0080135
IEA
PLAZA Integrative Orthologyregulation of cellular response to stress FBgn0000173
GO:0080134
IEA
PLAZA Integrative Orthologyregulation of response to stress FBgn0000173
GO:0120113
IEA
PLAZA Integrative Orthologyprotein localization by the NVT pathway SPAC11E3.04c
GO:0061057
IEA
PLAZA Integrative Orthologypeptidoglycan recognition protein signaling pathway FBgn0000173
GO:0010562
IEA
PLAZA Integrative Orthologypositive regulation of phosphorus metabolic process FBgn0000173
GO:0050789
IEA
PLAZA Integrative Orthologyregulation of biological process WBGene00006708
GO:0042493
IEA
PLAZA Integrative Orthologyresponse to drug FBgn0000173
GO:0007049
IEA
PLAZA Integrative Orthologycell cycle FBgn0000173
GO:0006513
IEA
PLAZA Integrative Orthologyprotein monoubiquitination YDR092W
GO:0048589
IEA
PLAZA Integrative Orthologydevelopmental growth FBgn0000173
GO:0048468
IEA
PLAZA Integrative Orthologycell development FBgn0000173
GO:0007166
IEA
PLAZA Integrative Orthologycell surface receptor signaling pathway FBgn0000173
GO:0045995
IEA
PLAZA Integrative Orthologyregulation of embryonic development FBgn0000173
GO:0007165
IEA
PLAZA Integrative Orthologysignal transduction FBgn0000173
GO:0016310
IEA
PLAZA Integrative Orthologyphosphorylation FBgn0000173
GO:0071478
IEA
PLAZA Integrative Orthologycellular response to radiation SPAC11E3.04c
GO:0034644
IEA
PLAZA Integrative Orthologycellular response to UV SPAC11E3.04c
GO:0048583
IEA
PLAZA Integrative Orthologyregulation of response to stimulus FBgn0000173
GO:0006979
IEA
PLAZA Integrative Orthologyresponse to oxidative stress FBgn0000173
GO:0048584
IEA
PLAZA Integrative Orthologypositive regulation of response to stimulus FBgn0000173
GO:1902533
IEA
PLAZA Integrative Orthologypositive regulation of intracellular signal transduction FBgn0000173
GO:0048699
IEA
PLAZA Integrative Orthologygeneration of neurons FBgn0000173
GO:0007399
IEA
PLAZA Integrative Orthologynervous system development FBgn0000173
GO:1902531
IEA
PLAZA Integrative Orthologyregulation of intracellular signal transduction FBgn0000173
GO:0007154
IEA
PLAZA Integrative Orthologycell communication FBgn0000173
GO:0043207
IEA
PLAZA Integrative Orthologyresponse to external biotic stimulus FBgn0000173
GO:0060341
IEA
PLAZA Integrative Orthologyregulation of cellular localization WBGene00006708
GO:0016567
IEA
PLAZA Integrative Orthologyprotein ubiquitination SPAC11E3.04c
GO:0051174
IEA
PLAZA Integrative Orthologyregulation of phosphorus metabolic process FBgn0000173
GO:0042592
IEA
PLAZA Integrative Orthologyhomeostatic process YDR092W
GO:0051179
IEA
PLAZA Integrative Orthologylocalization SPAC11E3.04c
GO:0045977
IEA
PLAZA Integrative Orthologypositive regulation of mitotic cell cycle, embryonic FBgn0000173
GO:0030182
IEA
PLAZA Integrative Orthologyneuron differentiation FBgn0000173
GO:0070914
IEA
PLAZA Integrative OrthologyUV-damage excision repair SPAC11E3.04c
GO:0051726
IEA
PLAZA Integrative Orthologyregulation of cell cycle FBgn0000173
GO:0071214
IEA
PLAZA Integrative Orthologycellular response to abiotic stimulus SPAC11E3.04c
GO:0072665
IEA
PLAZA Integrative Orthologyprotein localization to vacuole SPAC11E3.04c
GO:0031396
IEA
PLAZA Integrative Orthologyregulation of protein ubiquitination FBgn0000173
GO:0031399
IEA
PLAZA Integrative Orthologyregulation of protein modification process FBgn0000173
GO:0031398
IEA
PLAZA Integrative Orthologypositive regulation of protein ubiquitination FBgn0000173
GO:0042461
IEA
PLAZA Integrative Orthologyphotoreceptor cell development FBgn0000173
GO:0044085
IEA
PLAZA Integrative Orthologycellular component biogenesis YDR092W
GO:0007610
IEA
PLAZA Integrative Orthologybehavior FBgn0000173
GO:0051171
IEA
PLAZA Integrative Orthologyregulation of nitrogen compound metabolic process FBgn0000173
GO:0051173
IEA
PLAZA Integrative Orthologypositive regulation of nitrogen compound metabolic process FBgn0000173
GO:2000026
IEA
PLAZA Integrative Orthologyregulation of multicellular organismal development FBgn0000173
GO:0031323
IEA
PLAZA Integrative Orthologyregulation of cellular metabolic process FBgn0000173
GO:0080090
IEA
PLAZA Integrative Orthologyregulation of primary metabolic process FBgn0000173
GO:0031325
IEA
PLAZA Integrative Orthologypositive regulation of cellular metabolic process FBgn0000173
GO:0010646
IEA
PLAZA Integrative Orthologyregulation of cell communication FBgn0000173
GO:0001934
IEA
PLAZA Integrative Orthologypositive regulation of protein phosphorylation FBgn0000173
GO:0010647
IEA
PLAZA Integrative Orthologypositive regulation of cell communication FBgn0000173
GO:0001932
IEA
PLAZA Integrative Orthologyregulation of protein phosphorylation FBgn0000173
GO:0046530
IEA
PLAZA Integrative Orthologyphotoreceptor cell differentiation FBgn0000173
GO:0006952
IEA
PLAZA Integrative Orthologydefense response FBgn0000173
GO:0060255
IEA
PLAZA Integrative Orthologyregulation of macromolecule metabolic process FBgn0000173
GO:0043933
IEA
PLAZA Integrative Orthologyprotein-containing complex subunit organization YDR092W
GO:0010994
IEA
PLAZA Integrative Orthologyfree ubiquitin chain polymerization YDR092W
GO:0010992
IEA
PLAZA Integrative Orthologyubiquitin recycling YDR092W
GO:0019222
IEA
PLAZA Integrative Orthologyregulation of metabolic process FBgn0000173
GO:0019220
IEA
PLAZA Integrative Orthologyregulation of phosphate metabolic process FBgn0000173
GO:0000165
IEA
PLAZA Integrative OrthologyMAPK cascade FBgn0000173
GO:0000278
IEA
PLAZA Integrative Orthologymitotic cell cycle FBgn0000173
GO:0009416
IEA
PLAZA Integrative Orthologyresponse to light stimulus SPAC11E3.04c
GO:0009411
IEA
PLAZA Integrative Orthologyresponse to UV SPAC11E3.04c
GO:0045787
IEA
PLAZA Integrative Orthologypositive regulation of cell cycle FBgn0000173
GO:0048812
IEA
PLAZA Integrative Orthologyneuron projection morphogenesis FBgn0000173
GO:0009893
IEA
PLAZA Integrative Orthologypositive regulation of metabolic process FBgn0000173
GO:0034613
IEA
PLAZA Integrative Orthologycellular protein localization SPAC11E3.04c
GO:0023052
IEA
PLAZA Integrative Orthologysignaling FBgn0000173
GO:0023051
IEA
PLAZA Integrative Orthologyregulation of signaling FBgn0000173
GO:0023056
IEA
PLAZA Integrative Orthologypositive regulation of signaling FBgn0000173
GO:2000008
IEA
PLAZA Integrative Orthologyregulation of protein localization to cell surface WBGene00006708
GO:0071482
IEA
PLAZA Integrative Orthologycellular response to light stimulus SPAC11E3.04c
GO:0008594
IEA
PLAZA Integrative Orthologyphotoreceptor cell morphogenesis FBgn0000173
GO:0065003
IEA
PLAZA Integrative Orthologyprotein-containing complex assembly YDR092W
GO:0061564
IEA
PLAZA Integrative Orthologyaxon development FBgn0000173
GO:0065008
IEA
PLAZA Integrative Orthologyregulation of biological quality YDR092W
GO:0065007
IEA
PLAZA Integrative Orthologybiological regulation YDR092W
GO:0051403
IEA
PLAZA Integrative Orthologystress-activated MAPK cascade FBgn0000173
GO:0032446
IEA
PLAZA Integrative Orthologyprotein modification by small protein conjugation SPAC11E3.04c
GO:0072347
IEA
PLAZA Integrative Orthologyresponse to anesthetic FBgn0000173
GO:0034622
IEA
PLAZA Integrative Orthologycellular protein-containing complex assembly YDR092W
GO:0008219
IEA
PLAZA Integrative Orthologycell death FBgn0000173
GO:0050794
IEA
PLAZA Integrative Orthologyregulation of cellular process FBgn0000173
GO:0051641
IEA
PLAZA Integrative Orthologycellular localization SPAC11E3.04c
GO:0050793
IEA
PLAZA Integrative Orthologyregulation of developmental process FBgn0000173
GO:0051094
IEA
PLAZA Integrative Orthologypositive regulation of developmental process FBgn0000173
GO:0007254
IEA
PLAZA Integrative OrthologyJNK cascade FBgn0000173
GO:0008344
IEA
PLAZA Integrative Orthologyadult locomotory behavior FBgn0000173
GO:0009314
IEA
PLAZA Integrative Orthologyresponse to radiation SPAC11E3.04c
GO:0008104
IEA
PLAZA Integrative Orthologyprotein localization SPAC11E3.04c
GO:0030030
IEA
PLAZA Integrative Orthologycell projection organization FBgn0000173
GO:0009794
IEA
PLAZA Integrative Orthologyregulation of mitotic cell cycle, embryonic FBgn0000173
GO:0070727
IEA
PLAZA Integrative Orthologycellular macromolecule localization SPAC11E3.04c
GO:0009790
IEA
PLAZA Integrative Orthologyembryo development FBgn0000173

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Gene Ontologyprotein binding3 4 9 10 11 12
GO:0004842
IDA
ISS
Gene Ontologyubiquitin-protein transferase activity7 8 13
GO:0019899
IEA
PLAZA Integrative Orthologyenzyme binding FBgn0000173
GO:0044390
IEA
PLAZA Integrative Orthologyubiquitin-like protein conjugating enzyme binding FBgn0000173
GO:0044389
IEA
PLAZA Integrative Orthologyubiquitin-like protein ligase binding FBgn0000173
GO:0061631
IEA
PLAZA Integrative Orthologyubiquitin conjugating enzyme activity SPAC11E3.04c
GO:0061630
IEA
PLAZA Integrative Orthologyubiquitin protein ligase activity SPAC11E3.04c
GO:0031625
IEA
PLAZA Integrative Orthologyubiquitin protein ligase binding FBgn0000173
GO:0031624
IEA
PLAZA Integrative Orthologyubiquitin conjugating enzyme binding FBgn0000173
GO:0061659
IEA
PLAZA Integrative Orthologyubiquitin-like protein ligase activity SPAC11E3.04c
GO:0061650
IEA
PLAZA Integrative Orthologyubiquitin-like protein conjugating enzyme activity SPAC11E3.04c

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0031372
IPI
Gene OntologyUBC13-MMS2 complex3 4
GO:0009507
ISM
Gene Ontologychloroplast14
GO:0005634
ISM
Gene Ontologynucleus14
GO:0016020
IEA
PLAZA Integrative Orthologymembrane AT1G16890
GO:0005829
IEA
PLAZA Integrative Orthologycytosol SPAC11E3.04c
GO:0048471
IEA
PLAZA Integrative Orthologyperinuclear region of cytoplasm FBgn0000173
GO:0071944
IEA
PLAZA Integrative Orthologycell periphery AT1G16890
GO:0035370
IEA
PLAZA Integrative OrthologyUBC13-UEV1A complex FBgn0000173
GO:0005886
IEA
PLAZA Integrative Orthologyplasma membrane AT1G16890

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR016135Ubiquitin-conjugating enzyme/RWD-like
IPR000608Ubiquitin-conjugating enzyme E2
IPR023313Ubiquitin-conjugating enzyme, active site

No MapMan annotations defined for this gene.
KeggID Description
K10580UBE2N, BLU, UBC13; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
No chloroplast target sequence found.