Gene: AT1G67500 (Arabidopsis thaliana)

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Gene Identifier
AT1G67500
Transcript Identifier
AT1G67500.2
Gene Type
Coding gene
Location
1 : 25287707-25296714 : negative

Family Information

Homologous gene family
HOM02SEM000498
(77 genes in 26 species)
specific family
Orthologous gene family
ORTHO02SEM000595
(67 genes in 26 species)
specific family

Descriptions

Curated Summary
Encodes the catalytic subunit of DNA polymerase zeta.Mutants are sensitive to UV-B radiation. Gene is involved in damage-tolerance mechanisms through translesion synthesis(TLS).
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Identifiers

Type Value
aliasREV3
aliasrecovery protein 3
aliasATREV3

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006281
IDA
Gene OntologyDNA repair1 2
GO:0006281
IEA
InterProDNA repair
GO:0019985
IEA
InterProtranslesion synthesis
GO:0071494
IMP
Gene Ontologycellular response to UV-C3 4
GO:0006974
IMP
Gene Ontologycellular response to DNA damage stimulus3 4
GO:0010224
IMP
Gene Ontologyresponse to UV-B1 2
GO:0009411
IMP
Gene Ontologyresponse to UV1 2
GO:1904161
IEA
PLAZA Integrative OrthologyDNA synthesis involved in UV-damage excision repair SPBC336.04
GO:0030154
IEA
PLAZA Integrative Orthologycell differentiation FBgn0263600
GO:0044270
IEA
PLAZA Integrative Orthologycellular nitrogen compound catabolic process YDL102W
GO:0000002
IEA
PLAZA Integrative Orthologymitochondrial genome maintenance SPAC688.10
GO:0048869
IEA
PLAZA Integrative Orthologycellular developmental process FBgn0263600
GO:0007049
IEA
PLAZA Integrative Orthologycell cycle SPBC336.04
GO:0043137
IEA
PLAZA Integrative OrthologyDNA replication, removal of RNA primer YDL102W
GO:0007005
IEA
PLAZA Integrative Orthologymitochondrion organization SPAC688.10
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization SPAC688.10
GO:1902983
IEA
PLAZA Integrative OrthologyDNA strand elongation involved in mitotic DNA replication SPBC336.04
GO:0044786
IEA
PLAZA Integrative Orthologycell cycle DNA replication SPBC336.04
GO:1901575
IEA
PLAZA Integrative Orthologyorganic substance catabolic process YDL102W
GO:0006310
IEA
PLAZA Integrative OrthologyDNA recombination FBgn0002891
GO:0006278
IEA
PLAZA Integrative OrthologyRNA-dependent DNA biosynthetic process YDL102W
GO:0000724
IEA
PLAZA Integrative Orthologydouble-strand break repair via homologous recombination FBgn0002891
GO:0000725
IEA
PLAZA Integrative Orthologyrecombinational repair FBgn0002891
GO:0022616
IEA
PLAZA Integrative OrthologyDNA strand elongation SPBC336.04
GO:0006271
IEA
PLAZA Integrative OrthologyDNA strand elongation involved in DNA replication SPBC336.04
GO:0006273
IEA
PLAZA Integrative Orthologylagging strand elongation SPBC336.04
GO:0070987
IEA
PLAZA Integrative Orthologyerror-free translesion synthesis SPAC688.10
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process FBgn0263600
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process FBgn0263600
GO:0044265
IEA
PLAZA Integrative Orthologycellular macromolecule catabolic process YDL102W
GO:1902969
IEA
PLAZA Integrative Orthologymitotic DNA replication SPBC336.04
GO:0006302
IEA
PLAZA Integrative Orthologydouble-strand break repair FBgn0002891
GO:0016070
IEA
PLAZA Integrative OrthologyRNA metabolic process SPBC336.04
GO:0000278
IEA
PLAZA Integrative Orthologymitotic cell cycle SPBC336.04
GO:0042276
IEA
PLAZA Integrative Orthologyerror-prone translesion synthesis SPAC688.10
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development FBgn0263600
GO:0007399
IEA
PLAZA Integrative Orthologynervous system development FBgn0263600
GO:0006261
IEA
PLAZA Integrative OrthologyDNA-dependent DNA replication SPBC336.04
GO:0006260
IEA
PLAZA Integrative OrthologyDNA replication SPBC336.04
GO:0009056
IEA
PLAZA Integrative Orthologycatabolic process YDL102W
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development FBgn0263600
GO:0009057
IEA
PLAZA Integrative Orthologymacromolecule catabolic process YDL102W
GO:1901361
IEA
PLAZA Integrative Orthologyorganic cyclic compound catabolic process YDL102W
GO:1902296
IEA
PLAZA Integrative OrthologyDNA strand elongation involved in cell cycle DNA replication SPBC336.04
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis SPAC688.10
GO:0034655
IEA
PLAZA Integrative Orthologynucleobase-containing compound catabolic process YDL102W
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization SPAC688.10
GO:0048731
IEA
PLAZA Integrative Orthologysystem development FBgn0263600
GO:0044248
IEA
PLAZA Integrative Orthologycellular catabolic process YDL102W
GO:0046700
IEA
PLAZA Integrative Orthologyheterocycle catabolic process YDL102W
GO:1903459
IEA
PLAZA Integrative Orthologymitotic DNA replication lagging strand elongation SPBC336.04
GO:0032042
IEA
PLAZA Integrative Orthologymitochondrial DNA metabolic process SPAC688.10
GO:0070914
IEA
PLAZA Integrative OrthologyUV-damage excision repair SPBC336.04
GO:0006401
IEA
PLAZA Integrative OrthologyRNA catabolic process YDL102W
GO:1902319
IEA
PLAZA Integrative OrthologyDNA strand elongation involved in nuclear cell cycle DNA replication SPBC336.04
GO:0045005
IEA
PLAZA Integrative OrthologyDNA-dependent DNA replication maintenance of fidelity YDL102W
GO:0022008
IEA
PLAZA Integrative Orthologyneurogenesis FBgn0263600
GO:0022402
IEA
PLAZA Integrative Orthologycell cycle process SPBC336.04
GO:1903047
IEA
PLAZA Integrative Orthologymitotic cell cycle process SPBC336.04
GO:0019439
IEA
PLAZA Integrative Orthologyaromatic compound catabolic process YDL102W
GO:0033260
IEA
PLAZA Integrative Orthologynuclear DNA replication SPBC336.04
GO:0043504
IEA
PLAZA Integrative Orthologymitochondrial DNA repair SPAC688.10

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003676
IEA
InterPronucleic acid binding
GO:0000166
IEA
InterPronucleotide binding
GO:0003677
ISS
Gene OntologyDNA binding5
GO:0003677
IEA
InterProDNA binding
GO:0008408
IEA
InterPro3'-5' exonuclease activity
GO:0003887
ISS
Gene OntologyDNA-directed DNA polymerase activity1 2
GO:0003887
IEA
InterProDNA-directed DNA polymerase activity
GO:0004529
IEA
PLAZA Integrative Orthologyexodeoxyribonuclease activity YDL102W
GO:0008296
IEA
PLAZA Integrative Orthology3'-5'-exodeoxyribonuclease activity YDL102W
GO:0016796
IEA
PLAZA Integrative Orthologyexonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters YDL102W
GO:0005515
IEA
PLAZA Integrative Orthologyprotein binding SPBC336.04
GO:0016895
IEA
PLAZA Integrative Orthologyexodeoxyribonuclease activity, producing 5'-phosphomonoesters YDL102W
GO:0004536
IEA
PLAZA Integrative Orthologydeoxyribonuclease activity YDL102W

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016035
ISS
Gene Ontologyzeta DNA polymerase complex1 2
GO:0016035
IEA
InterProzeta DNA polymerase complex
GO:0005634
ISM
Gene Ontologynucleus6
GO:0005739
IEA
PLAZA Integrative Orthologymitochondrion YPL167C
GO:0044430
IEA
PLAZA Integrative Orthologycytoskeletal part FBgn0263600
GO:0098687
IEA
PLAZA Integrative Orthologychromosomal region SPBC336.04
GO:0005737
IEA
PLAZA Integrative Orthologycytoplasm SPAC688.10
GO:0070013
IEA
PLAZA Integrative Orthologyintracellular organelle lumen SPAC688.10
GO:0005856
IEA
PLAZA Integrative Orthologycytoskeleton FBgn0263600
GO:0005657
IEA
PLAZA Integrative Orthologyreplication fork SPAC688.10
GO:0044427
IEA
PLAZA Integrative Orthologychromosomal part SPAC688.10
GO:0044428
IEA
PLAZA Integrative Orthologynuclear part SPAC688.10
GO:0031974
IEA
PLAZA Integrative Orthologymembrane-enclosed lumen SPAC688.10
GO:0043601
IEA
PLAZA Integrative Orthologynuclear replisome SPBC336.04
GO:0005654
IEA
PLAZA Integrative Orthologynucleoplasm ENSG00000009413
GO:0005694
IEA
PLAZA Integrative Orthologychromosome SPAC688.10
GO:0044454
IEA
PLAZA Integrative Orthologynuclear chromosome part SPAC688.10
GO:0030894
IEA
PLAZA Integrative Orthologyreplisome SPBC336.04
GO:0032993
IEA
PLAZA Integrative Orthologyprotein-DNA complex SPBC336.04
GO:0031981
IEA
PLAZA Integrative Orthologynuclear lumen SPAC688.10
GO:0000790
IEA
PLAZA Integrative Orthologynuclear chromatin YPL167C
GO:0000784
IEA
PLAZA Integrative Orthologynuclear chromosome, telomeric region SPBC336.04
GO:0000785
IEA
PLAZA Integrative Orthologychromatin YPL167C
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part SPAC688.10
GO:0043232
IEA
PLAZA Integrative Orthologyintracellular non-membrane-bounded organelle SPAC688.10
GO:0043233
IEA
PLAZA Integrative Orthologyorganelle lumen SPAC688.10
GO:0000228
IEA
PLAZA Integrative Orthologynuclear chromosome SPAC688.10
GO:0043596
IEA
PLAZA Integrative Orthologynuclear replication fork SPAC688.10
GO:0005829
IEA
PLAZA Integrative Orthologycytosol SPAC688.10
GO:0000781
IEA
PLAZA Integrative Orthologychromosome, telomeric region SPBC336.04
GO:0005875
IEA
PLAZA Integrative Orthologymicrotubule associated complex FBgn0263600
GO:0043228
IEA
PLAZA Integrative Orthologynon-membrane-bounded organelle SPAC688.10
GO:0015630
IEA
PLAZA Integrative Orthologymicrotubule cytoskeleton FBgn0263600
GO:0043625
IEA
PLAZA Integrative Orthologydelta DNA polymerase complex SPBC336.04

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR012337Ribonuclease H-like superfamily
IPR023211DNA polymerase, palm domain superfamily
IPR030559DNA polymerase zeta catalytic subunit
IPR006134DNA-directed DNA polymerase, family B, multifunctional domain
IPR025687C4-type zinc-finger of DNA polymerase delta
IPR006133DNA-directed DNA polymerase, family B, exonuclease domain
IPR006172DNA-directed DNA polymerase, family B
IPR017964DNA-directed DNA polymerase, family B, conserved site

No MapMan annotations defined for this gene.
KeggID Description
K02350REV3L, POLZ; DNA polymerase zeta [EC:2.7.7.7]
No chloroplast target sequence found.