Gene: AT1G12480 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G12480
Transcript Identifier
AT1G12480.1
Gene Type
Coding gene
Location
1 : 4257427-4259249 : negative

Family Information

Homologous gene family
HOM02SEM006406
(13 genes in 5 species)
specific family
Orthologous gene family
ORTHO02SEM006110
(13 genes in 5 species)
specific family

Descriptions

Description
C4-dicarboxylate transporter/malic acid transport protein
Curated Summary
Encodes a membrane protein with 10 predicted transmembrane helices. SLAC1 is a multispanning membrane protein expressed predominantly in guard cells that plays a role in regulating cellular ion homeostasis and S-type anion currents. SLAC1 is important for normal stomatal closure in response to a variety of signals including elevated CO2, ozone, ABA, darkness, and humidity. SLAC1:GFP localizes to the plasma membrane.
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Identifiers

Type Value
uniprotQ9LD83
aliasOZS1
aliasCDI3
aliasSLAC1
aliasRADICAL-INDUCED CELL DEATH 3
aliasSLOW ANION CHANNEL-ASSOCIATED 1
aliasRCD3
aliasOZONE-SENSITIVE 1
aliasCARBON DIOXIDE INSENSITIVE 3

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0055085
IEA
InterProtransmembrane transport
GO:1902456
IMP
Gene Ontologyregulation of stomatal opening1 2
GO:0090332
IMP
Gene Ontologystomatal closure3 4
GO:0050891
IMP
Gene Ontologymulticellular organismal water homeostasis5 6
GO:0010193
IMP
Gene Ontologyresponse to ozone5 6
GO:0010118
IMP
Gene Ontologystomatal movement5 6
GO:0010037
IMP
Gene Ontologyresponse to carbon dioxide5 6
GO:0009737
IMP
Gene Ontologyresponse to abscisic acid5 6
GO:0009270
IMP
Gene Ontologyresponse to humidity5 6
GO:0006820
IMP
Gene Ontologyanion transport5 6
GO:0006873
IMP
Gene Ontologycellular ion homeostasis7 8
GO:0044070
IEA
PLAZA Integrative Orthologyregulation of anion transport AT1G62280
GO:0032412
IEA
PLAZA Integrative Orthologyregulation of ion transmembrane transporter activity AT1G62280
GO:0032414
IEA
PLAZA Integrative Orthologypositive regulation of ion transmembrane transporter activity AT1G62280
GO:0032411
IEA
PLAZA Integrative Orthologypositive regulation of transporter activity AT1G62280
GO:0032879
IEA
PLAZA Integrative Orthologyregulation of localization AT1G62280
GO:0044093
IEA
PLAZA Integrative Orthologypositive regulation of molecular function AT1G62280
GO:1901529
IEA
PLAZA Integrative Orthologypositive regulation of anion channel activity AT1G62280
GO:0065009
IEA
PLAZA Integrative Orthologyregulation of molecular function AT1G62280
GO:0022898
IEA
PLAZA Integrative Orthologyregulation of transmembrane transporter activity AT1G62280
GO:0006970
IEA
PLAZA Integrative Orthologyresponse to osmotic stress AT1G62280
GO:1903793
IEA
PLAZA Integrative Orthologypositive regulation of anion transport AT1G62280
GO:0034220
IEA
PLAZA Integrative Orthologyion transmembrane transport AT1G62280
GO:0034767
IEA
PLAZA Integrative Orthologypositive regulation of ion transmembrane transport AT1G62280
GO:0034762
IEA
PLAZA Integrative Orthologyregulation of transmembrane transport AT1G62280
GO:0010359
IEA
PLAZA Integrative Orthologyregulation of anion channel activity AT1G62280
GO:0034764
IEA
PLAZA Integrative Orthologypositive regulation of transmembrane transport AT1G62280
GO:0034765
IEA
PLAZA Integrative Orthologyregulation of ion transmembrane transport AT1G62280
GO:0032409
IEA
PLAZA Integrative Orthologyregulation of transporter activity AT1G62280
GO:0098656
IEA
PLAZA Integrative Orthologyanion transmembrane transport AT1G62280
GO:0043270
IEA
PLAZA Integrative Orthologypositive regulation of ion transport AT1G62280
GO:1903959
IEA
PLAZA Integrative Orthologyregulation of anion transmembrane transport AT1G62280
GO:0051049
IEA
PLAZA Integrative Orthologyregulation of transport AT1G62280
GO:0009414
IEA
PLAZA Integrative Orthologyresponse to water deprivation AT1G62280
GO:0006821
IEA
PLAZA Integrative Orthologychloride transport AT1G62280
GO:0048518
IEA
PLAZA Integrative Orthologypositive regulation of biological process AT1G62280
GO:0043269
IEA
PLAZA Integrative Orthologyregulation of ion transport AT1G62280
GO:0051050
IEA
PLAZA Integrative Orthologypositive regulation of transport AT1G62280
GO:1903961
IEA
PLAZA Integrative Orthologypositive regulation of anion transmembrane transport AT1G62280
GO:0009651
IEA
PLAZA Integrative Orthologyresponse to salt stress AT1G62280
GO:0015698
IEA
PLAZA Integrative Orthologyinorganic anion transport AT1G62280

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0019901
IPI
Gene Ontologyprotein kinase binding9 10
GO:0008308
IDA
Gene Ontologyvoltage-gated anion channel activity9 10
GO:0005515
IPI
Gene Ontologyprotein binding9 10 11 12 13 14
GO:0008509
IDA
Gene Ontologyanion transmembrane transporter activity5 6
GO:0005215
ISS
Gene Ontologytransporter activity15

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016021
ISS
Gene Ontologyintegral component of membrane15
GO:0016021
IEA
InterProintegral component of membrane
GO:0005886
IDA
Gene Ontologyplasma membrane7 8
GO:0005634
ISM
Gene Ontologynucleus16

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR004695Voltage-dependent anion channel
IPR030183S-type anion channel

No MapMan annotations defined for this gene.
No Kegg annotations defined for this gene.
No chloroplast target sequence found.