Gene: AT5G02100 (Arabidopsis thaliana)

Overview

Gene Identifier
AT5G02100
Transcript Identifier
AT5G02100.1
Gene Type
Coding gene
Location
5 : 413639-416016 : positive

Family

Gene family
HOM03D003745
(33 genes in 16 species)
specific family

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Descriptions

Description
Oxysterol-binding family protein
Curated Summary
Encodes a protein that binds to beta-sitosterol and localizes to the ER. The WFDE motif in ORP3a appears to be important for a direct interaction with PVA12 [Plant VAMP-Associated protein 12]. Mutation of this motif causes ORP3a to relocalize to the Golgi and cytosol. The interaction between PVA12 and ORP3a does not appear to be sterol-dependent.
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Identifiers

Identifier Name
aliasUNE18
aliasOSBP(OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 3A
aliasORP3A
aliasUNFERTILIZED EMBRYO SAC 18
uniprotQ9LZM1

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0008202ISSGene Ontologysteroid metabolic process
GO:0009567IMPUniProtdouble fertilization forming a zygote and endosperm1 2 3 4 5 6
GO:0006888RCAGene OntologyER to Golgi vesicle-mediated transport1
GO:0006869IEAUniProtlipid transport1 2 3 4 5
GO:0007338IEAUniProtsingle fertilization1 2 3 4 5

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0008142ISSGene Ontologyoxysterol binding
GO:0005515IPIGene Ontologyprotein binding1
GO:0032934IDAUniProtsterol binding1 2 3 4 5 6
GO:0005543IEAPLAZA Homologyphospholipid bindingHOM03D000549

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634ISMGene Ontologynucleus
GO:0005783IDAUniProtendoplasmic reticulum1 2 3 4 5 6
GO:0005829RCAGene Ontologycytosol1
GO:0005794IEAUniProtGolgi apparatus1 2 3 4 5

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Computational Reviewed Evidence
Electronic Evidence
Experimental Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR018494Oxysterol-binding protein, conserved site
IPR000648Oxysterol-binding protein
Mapman id Description
31.4cell.vesicle transport
No SignalP domains detected for this gene.