Gene: AT1G71750 (Arabidopsis thaliana)

Overview

Gene Identifier
AT1G71750
Transcript Identifier
AT1G71750.2
Gene Type
Coding gene
Location
1 : 26987954-26989144 : negative

Family

Gene family
HOM03D007652
(16 genes in 7 species)
specific family

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Descriptions

Description
Hypoxanthine-guanine phosphoribosyltransferase
Curated Summary
Encodes a protein with hypoxanthine-guanine-phosphoribosyltransferase activity. Unlike some related enzymes, it does not appear to act on xanthine in vitro. The enzyme catalyzes reactions occurring in both directions, but appears to prefer acting on guanine, followed by hypoxanthine, in vitro. The enzyme is likely to function in purine salvage pathways and appears to be important for seed germination.
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Identifiers

Identifier Name
aliasHypoxanthine-guanine phosphoribosyltransferase
aliasHGPT

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006166IBA, IEAGene Ontologypurine ribonucleoside salvage
GO:0006168IBAGene Ontologyadenine salvage
GO:0006178IBAGene Ontologyguanine salvage
GO:0009116ISS, IEAGene Ontologynucleoside metabolic process
GO:0032263IBAGene OntologyGMP salvage
GO:0032264IBAGene OntologyIMP salvage
GO:0009845IMPGene Ontologyseed germination1
GO:0046098IDAGene Ontologyguanine metabolic process1
GO:0046100IDAGene Ontologyhypoxanthine metabolic process1
GO:0043174IEAPLAZA Homologynucleoside salvageHOM03D005949

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0000287IBAGene Ontologymagnesium ion binding
GO:0016740ISSGene Ontologytransferase activity
GO:0004422IDA, IEAGene Ontologyhypoxanthine phosphoribosyltransferase activity1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737ISM, IEAGene Ontologycytoplasm
GO:0005829IBA, IDAGene Ontologycytosol1

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Computational Reviewed Evidence
Electronic Evidence
Experimental Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR005904Hypoxanthine phosphoribosyl transferase
IPR000836Phosphoribosyltransferase domain
Mapman id Description
23.3.1.2nucleotide metabolism.salvage.phosphoribosyltransferases.hgprt
No SignalP domains detected for this gene.